3QXE


Conserved Protein Domain Family
NHase_beta

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pfam02211: NHase_beta 
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Nitrile hydratase beta subunit
Nitrile hydratases EC:4.2.1.84 are unusual metalloenzymes that catalyze the hydration of nitriles to their corresponding amides. They are used as biocatalysts in acrylamide production, one of the few commercial scale bioprocesses, as well as in environmental remediation for the removal of nitriles from waste streams. Nitrile hydratases are composed of two subunits, alpha and beta, and they contain one iron atom per alpha beta unit.
Statistics
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PSSM-Id: 426662
Aligned: 41 rows
Threshold Bit Score: 221.349
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3QXE_B                     1 MNGIHDTGGAHGYGPVYREp--------nEPVFRYDWEKTVMSLLP-ALLANGN---------------F-NLDEFRHSI 55  Pse...
goetting:GPOL_c06990       1 MDGVHDLAGKQGFGPVDHTineydhgkpvPETFHADWEHLPYSLFFlGVAELNK---------------F-SVDEVRHVV 64  Gor...
WP_013232962               1 MDGFHDLGGVQGFGRIPHTins----ldyKKVFKQDWEHLAYTLMFlGADHMKL---------------Y-SVDEVRHAV 60  Her...
Q6FBU7                     1 MDGFHDLGGVQGFGAIDHKins----ksyKPVFKKDWEHLAYTLMFlGAGHLNK---------------F-NIDQVRHAV 60  Aci...
zhongguo:AS9A_3707        42 MKTVHDVGGEPD-APMKYE-----------NKQYEVWEHNTYVICE-VLAWRGI---------------WlSEERRRMGN 93  Hoy...
jgi:Mvan_1505             42 lkpVHDVGGEPD-APMKYE-----------NKQYEQWEELTYVICE-VLAWRGI---------------WlSEERRRIGN 93  Myc...
WP_015191231               1 MKLQHYLGGLEGLGRINFE----------KRVFVQPWERRIFGIHV-AMMALSQhletakvtptkfksvW-TWANLRKLA 68  Glo...
BAF89796                   1 MKLQHYLGGLEGLGPVSTE----------TRVFVEPWEKRIFGIHT-AMMALSTqlslpat-pssfrtvW-TWADLRKGA 67  Azo...
jgi:Msil_3459              1 MKLQHTLGGLEGLGPVWTE----------TRVFVEEWEKGIFGIHT-AMMALSPqlplpkt-psvfrtiW-TWADLRKGA 67  Met...
PRJNA391730:Sp245p_24440   1 MKLQHYLGGLEGLGPITVE----------TRVFVEEWEKRIFGIHT-AMMALSPqlplpat-psafrtvW-TWAHLRTGA 67  Azo...
3QXE_B                    56 ERMGPAHYLEGTYYEHWLHVFENLLVEKGVLTATEVATGkaasgkt-------------------atpvltPAIVDGLLS 116 Pse...
goetting:GPOL_c06990      65 ERIAPVHYLVTPYYERYAIGVATLMVETGVLTKDELEKF--------------------------------AGGPFPLSL 112 Gor...
WP_013232962              61 ERIEFRQQANTQYYERYVIATASLLVELGVLTQQELDEA--------------------------------LGSHFQLAR 108 Her...
Q6FBU7                    61 ERIGLRQHVGTEYYERYVIATATLLTEAGVITQQELDEA--------------------------------LGSHFQLAT 108 Aci...
zhongguo:AS9A_3707        94 VDVGRAVYLGIPYYGRWLLAVARVLVEKHHIGLGELSERmaevaaryeggldgkaiaaqpkfegdgsqvkrNKHHLHAVG 173 Hoy...
jgi:Mvan_1505             94 VDVGRAEYLGLPYYGRWLLAVARVLVEKHHIALGELSERmaevqaryadglngrkleaqpksagdgsdvkrNAHHKRAVG 173 Myc...
WP_015191231              69 EGMNPFDYFKYRYYEKWLGGISSFFIESGYVSTTELDAKteifleksnt------------slphnskpeiDAQVIEYLR 136 Glo...
BAF89796                  68 ESLNPLDYFRFRYYEKWIGGISSYFISHGYITEAELDALtkeyyadfsk------------prpsagcavvDARIVQYLV 135 Azo...
jgi:Msil_3459             68 ESMNPFDYFKYRYYEKWLGGISGYFVANGYITQAELDAKteeyyadpdk------------plptggatqiDERVIQYLV 135 Met...
PRJNA391730:Sp245p_24440  68 EGLNPFDYFKYRYYEKWLGGISGYFIENGYITEEELEARtaeyladpdk------------plpqggapeiDQRVERYLA 135 Azo...
3QXE_B                   117 TGASAAREEGA-RARFAVGDKVRVLNKNPVGHTRMPRYTRGKVGTVVID-HGVFVTPDTAA-HGKGEh-PQHVYTVSFTS 192 Pse...
goetting:GPOL_c06990     113 PATSEGRPARSdTPVFNVGDTVRVRDEHFAGHIRMPGICRGKTGVIRHRtAEKWPFPDAIG-HGRTDggAEPTYHVEFTG 191 Gor...
WP_013232962             109 PAQSKGRPAITgRPPFEVGDRVLVRDERVTGHIRCPGYVRGKEGVVLHRtTEQWPFPDTIG-HGDKSaaMQPTYHVQFSN 187 Her...
Q6FBU7                   109 PNHSTGRSAIAdRPPFEVGDQVTVRDEYVSGHIRVPAYVRGKTGVVVHRtTEKWPFPDAAG-HGHTDalPQPTYHVEFNT 187 Aci...
zhongguo:AS9A_3707       174 KGDPQVYAGQAgEPKFQVGDPVVVRELPALLYTRTPEYVRGAKGEIASVaYESPAAEDETW--DRPDakAEWFYVVRFNM 251 Hoy...
jgi:Mvan_1505            174 KGDPQIYAGQAgEAKFKVGDRVLVRDLPVLFYTRTPEYVRGATGEIDVVaYESPAAEDETW--DRPDakPEWFYIVKFAM 251 Myc...
WP_015191231             137 VGDSPKCKADI-KPKFSVGNIVTIKNPLPTEHCKLPGYLRNKKGVVDVVyEGVYNYPLQTG-DGVGD--PMPIYSIKFDS 212 Glo...
BAF89796                 136 EGDSPKRGAAV-NHAFAVGDAVAVCDVPTVEHTRLPGYLRNRTGTVETVyEGTYTYLCNTGpDGIGA--AMPVYCVRFDP 212 Azo...
jgi:Msil_3459            136 DGDSPKRDVDP-KPLFAKGDVVRVGNPPTVEHTRLPGFLRNHTGVIEEVyPGAYVYLCDTGpDGVGE--AMACYCVRFDP 212 Met...
PRJNA391730:Sp245p_24440 136 EGDSPKRDVAI-LPDFQEGDTVQVRNVPTLEHTRLPGFLRNHSGVVETVyPGAYGYLTDTGtDGVGA--PMPVYCVRFEA 212 Azo...
3QXE_B                   193 VELWGQDAsSPkDTIRVDLWDDYLEP 218 Pseudomonas putida
goetting:GPOL_c06990     192 EELFGEDT-DA-ASVMVDLFGGYLEP 215 Gordonia polyisoprenivorans VH2
WP_013232962             188 RDVWGDAC-DD-GFVVVDLFEGYLDK 211 Herbaspirillum seropedicae
Q6FBU7                   188 QELWGDAA-DA-GYVVVDLFESYLDK 211 Acinetobacter baylyi
zhongguo:AS9A_3707       252 AELWHGYTgTTdDSLQTELPERWLKA 277 Hoyosella subflava DQS3-9A1
jgi:Mvan_1505            252 SDLWHGYTgTStDTLRTEIPERWLAa 277 Mycolicibacterium vanbaalenii PYR-1
WP_015191231             213 HEIWGNLT-EPkTWIYADIYEAYIEN 237 Gloeocapsa sp. PCC 7428
BAF89796                 213 VTIWPGNA-EPnFAIYADLYAHYIAa 237 Azorhizobium caulinodans ORS 571
jgi:Msil_3459            213 EELWPGNA-EKnFFIYADLYAAYLTa 237 Methylocella silvestris BL2
PRJNA391730:Sp245p_24440 213 KDLWPGNT-EPnVTLYADLYAAYVTK 237 Azospirillum brasilense Sp245
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