5FZ5


Conserved Protein Domain Family
TFIIE_beta

?
pfam02186: TFIIE_beta 
Click on image for an interactive view with Cn3D
TFIIE beta subunit core domain
General transcription factor TFIIE consists of two subunits, TFIIE alpha pfam02002 and TFIIE beta. TFIIE beta has been found to bind to the region where the promoter starts to open to be single-stranded upon transcription initiation by RNA polymerase II. The structure of the DNA binding core region has been solved and has a winged helix fold.
Statistics
?
PSSM-Id: 460479
Aligned: 66 rows
Threshold Bit Score: 54.0807
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
5FZ5_X              124 DSSKLLWATEYIQKKGK-PVLVNELLDYLSm----KKDD---KVIELLKKLDRIEFDPkk----gTFKYLSTYDV 186 baker's yeast
EMC98298             61 IFKVVVNTVEYLKGKNAaPVPFEEIIRYLSlp--vDLQRkqeTIKRALRTHNRVQQitid--gkeSFKYRPQHDV 131
EED17409             67 IMTNVLYAIQKMKEKNA-PLTFEDIVGYLSlqdrrHDQGyvhALRSILQVHDKVNYDPtgadgkgTFSFRPPHNI 140
CAP97518             77 IMTQVLFAIEHMKNKNI-PLKFSDIISYLSlqhraHDQGyvqALRSILQMHEKVEFDPsgangegTFRFRPPHNI 150
Q4WLL2               74 IMTQVLFAVEHLKSKGV-PLRYSDIVSYLSlqhrsSDEGylqALRRILTQHEKVLYDPsgangegTFAFRPPHNI 147 Aspergillus f...
GAD92966             82 IMTQVLFAIEHMKTKGV-PLKFSDIVSYLSlqhraNDQGylhALRSILQVHEKVQFDPkgangegTFSFRPPHNI 155
EEQ85029             83 IMTQVVFAIDHMKSKDY-ALKFADILSYLSlqqqgHDPGyiqALKRILQSHDKVEYDPsgangegTFRFKPPHNI 156
XP_001247900         76 IMTQVVFAIEHMKSKDV-PLTFSDIQSYLSlhrqgHDQAyihALRRILQSHDKVDYDPqgskgegTFRFRPPHNI 149
WGS:ACPH:TERG_01089  74 IMTQVIFAIEHMKGKDV-PLKFSDIESYLSlsrqgHDMGyihALRRILQSHDKVQYDPagangegTFQFRPPHNI 147
XP_007782193         50 IHTQVHYAITYLQNKDR-ALSFDDILNYLSlr--sADLQrrkALRHILTLNPRVEFDPkgnngagSFRYRPIHPV 121
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap