O74559 33 SERACQFMEQAE-TFMAPFTPYMPLLGRFLIVATYFEDAIRIVTQWPEQVSYMRDYRRFRFGTAPLLLFVCVVLMLVGST 111 Schizosaccharomyces p... O18405 5 NEYIAKTEDVAE-QVIKRGKNVLPTVARLCLIATFFEDGLRMYIQWNEQREYMDMSWGCGKFLATVFVLVNLLGQLGGCG 83 fruit fly O15260 4 NDLMGTAEDFAD-QFLRVTKQYLPHVARLCLISTFLEDGIRMWFQWSEQRDYIDTTWNCGYLLASSFVFLNLLGQLTGCV 82 human Q18864 11 NEMLAKAEDAAE-DFFRKTRTYLPHIARLCLVSTFLEDGIRMYFQWDDQKQFMQESWSCGWFIATLFVIYNFFGQFIPVL 89 Caenorhabditis elegans O45731 4 NVVITRCEDYTE-TLARNTRKVLPTIGRLLLISTFVEDGLRLLFNTHDHVNHFSYNWGLNYHFSLFLTIVMIINLLFGSL 82 Caenorhabditis elegans P53337 48 EKFASRIEGLTDnAVVYKLKPYIPSLSRFFIVATFYEDSFRILSQWSDQIFYLNKWKHYPYFFVVVFLVVVTVSMLIGAS 127 Saccharomyces cerevis... O18405 5 NEYIAKTEDVAE-QVIKRGKNVLPTVARLCLIATFFEDGLRMYIQWNEQREYMDMSWGCGKFLATVFVLVNLLGQLGGCG 83 fruit fly O15260 4 NDLMGTAEDFAD-QFLRVTKQYLPHVARLCLISTFLEDGIRMWFQWSEQRDYIDTTWNCGYLLASSFVFLNLLGQLTGCV 82 human Q18864 11 NEMLAKAEDAAE-DFFRKTRTYLPHIARLCLVSTFLEDGIRMYFQWDDQKQFMQESWSCGWFIATLFVIYNFFGQFIPVL 89 Caenorhabditis elegans O45731 4 NVVITRCEDYTE-TLARNTRKVLPTIGRLLLISTFVEDGLRLLFNTHDHVNHFSYNWGLNYHFSLFLTIVMIINLLFGSL 82 Caenorhabditis elegans P53337 48 EKFASRIEGLTDnAVVYKLKPYIPSLSRFFIVATFYEDSFRILSQWSDQIFYLNKWKHYPYFFVVVFLVVVTVSMLIGAS 127 Saccharomyces cerevis...
O74559 112 LVVFKKRQAYAIGSLLFVTLLQAFAYGLITSGEMFFRNMSVIGGLCLVASDTFIHRRIn-RFAGLPAVSE--HNKRTYFQ 188 Schizosaccharomyces p... O18405 84 MVMARFKVDIAVGLLFFIVVLQTVAYSILWDFQFLLRNFALIGALLLVLAEARIEGRS--LFAGVPSMGE--NKPKNFMQ 159 fruit fly O15260 83 LVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRNLALGGGLLLLLAESRSEGKS--MFAGVPTMRE--SSPKQYMQ 158 human Q18864 90 MIMLRKKVLVACGILASIVILQTIAYHILWDLKFLARNIAVGGGLLLLLAETQEEKAS--LFAGVPTMGDs-NKPKSYML 166 Caenorhabditis elegans O45731 83 FVMMRYKVTESSAVLGFTIFAQVILYQLYTTYHLLTRNISIVAAIMLLVAENMLRKPKpaNYTQLPRDEHe-IEVTSVLL 161 Caenorhabditis elegans P53337 128 LLVLRKQTNYATGVLCACVISQALVYGLFTGSSFVLRNFSVIGGLLIAFSDSIVQNKT--TFGMLPELNSknDKAKGYLL 205 Saccharomyces cerevis... O18405 84 MVMARFKVDIAVGLLFFIVVLQTVAYSILWDFQFLLRNFALIGALLLVLAEARIEGRS--LFAGVPSMGE--NKPKNFMQ 159 fruit fly O15260 83 LVLSRNFVQYACFGLFGIIALQTIAYSILWDLKFLMRNLALGGGLLLLLAESRSEGKS--MFAGVPTMRE--SSPKQYMQ 158 human Q18864 90 MIMLRKKVLVACGILASIVILQTIAYHILWDLKFLARNIAVGGGLLLLLAETQEEKAS--LFAGVPTMGDs-NKPKSYML 166 Caenorhabditis elegans O45731 83 FVMMRYKVTESSAVLGFTIFAQVILYQLYTTYHLLTRNISIVAAIMLLVAENMLRKPKpaNYTQLPRDEHe-IEVTSVLL 161 Caenorhabditis elegans P53337 128 LLVLRKQTNYATGVLCACVISQALVYGLFTGSSFVLRNFSVIGGLLIAFSDSIVQNKT--TFGMLPELNSknDKAKGYLL 205 Saccharomyces cerevis...
O74559 189 LAGRVLLIFMFLGLLAKEgsgISWTRILVHILSVTACAMVVIGFKAKFFAAVLVLILSVANFIINSFWSVPRESPYRDFY 268 Schizosaccharomyces p... O18405 160 LAGRILLAFMFITLIRFE---LSVWQVIQDIIGSILMVLVVLGYKTKLSALILVALLTILNLYHNAWWTIPSYKPLRDFL 236 fruit fly O15260 159 LGGRVLLVLMFMTLLHFD---ASFFSIVQNIVGTALMILVAIGFKTKLAALTLVVWLFAINVYFNAFWTIPVYKPMHDFL 235 human Q18864 167 LAGRVLLIFMFMSLMHFE---MSFMQVLEIVVGFALITLVSIGYKTKLSAIVLVIWLFGLNLWLNAWWTIPSDRFYRDFM 243 Caenorhabditis elegans O45731 162 AACRVCLNLMLISMVHFD---MSYTRILLCIISYGMMIFVWLGFKTRMMSFMLATWLFAYNIVLNDFWN--KDAELH-II 235 Caenorhabditis elegans P53337 206 FAGRILIVLMFIAFTFSK----SWFTVVLTIIGT---ICFAIGYKTKFASIMLGLILTFYNITLNNYWFY--NNTKRDFL 276 Saccharomyces cerevis... O18405 160 LAGRILLAFMFITLIRFE---LSVWQVIQDIIGSILMVLVVLGYKTKLSALILVALLTILNLYHNAWWTIPSYKPLRDFL 236 fruit fly O15260 159 LGGRVLLVLMFMTLLHFD---ASFFSIVQNIVGTALMILVAIGFKTKLAALTLVVWLFAINVYFNAFWTIPVYKPMHDFL 235 human Q18864 167 LAGRVLLIFMFMSLMHFE---MSFMQVLEIVVGFALITLVSIGYKTKLSAIVLVIWLFGLNLWLNAWWTIPSDRFYRDFM 243 Caenorhabditis elegans O45731 162 AACRVCLNLMLISMVHFD---MSYTRILLCIISYGMMIFVWLGFKTRMMSFMLATWLFAYNIVLNDFWN--KDAELH-II 235 Caenorhabditis elegans P53337 206 FAGRILIVLMFIAFTFSK----SWFTVVLTIIGT---ICFAIGYKTKFASIMLGLILTFYNITLNNYWFY--NNTKRDFL 276 Saccharomyces cerevis...
O74559 269 RYDFFQTLSIVGGLLYLVNTGPGKFSVDEKKKIY 302 Schizosaccharomyces pombe 972h- O18405 237 KYDFFQTLSVIGGLLMIVSLGPGGVSMDEHKKKW 270 fruit fly O15260 236 KYDFFQTMSVIGGLLLVVALGPGGVSMDEKKKEW 269 human Q18864 244 KYDFFQTMSVIGGLLLVIAYGPGGVSVDDYKKRW 277 Caenorhabditis elegans O45731 236 RYDFFQTLSAIGGLLLLIHTGPGEFSFDELKKKW 269 Caenorhabditis elegans P53337 277 KYEFYQNLSIIGGLLLVTNTGAGELSVDEKKKIY 310 Saccharomyces cerevisiae S288C O18405 237 KYDFFQTLSVIGGLLMIVSLGPGGVSMDEHKKKW 270 fruit fly O15260 236 KYDFFQTMSVIGGLLLVVALGPGGVSMDEKKKEW 269 human Q18864 244 KYDFFQTMSVIGGLLLVIAYGPGGVSVDDYKKRW 277 Caenorhabditis elegans O45731 236 RYDFFQTLSAIGGLLLLIHTGPGEFSFDELKKKW 269 Caenorhabditis elegans P53337 277 KYEFYQNLSIIGGLLLVTNTGAGELSVDEKKKIY 310 Saccharomyces cerevisiae S288C
Lu S et al.(2020). "CDD/SPARCLE: the conserved domain database in 2020.",