Conserved Protein Domain Family
Enterotoxin_ST
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pfam02048: Enterotoxin_ST 
Heat-stable enterotoxin ST
This family consists of the heat stable enterotoxin ST from Escherichia coli. ST is a small peptide of 18 or 19 amino acid residues produced by enterotoxigenic E. coli and is one of the causes of acute diarrhoea in infants and travellers in developing countries. ST triggers a biological response by binding to a membrane-associated guanylyl cyclase C which is located on intestinal epithelial cell membranes.
Links
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Statistics
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PSSM-Id: 307942
Aligned: 6 rows
Threshold Bit Score: 44.9576
Created: 21-Mar-2022
Updated: 13-Oct-2022
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
O50319       20 QETASGQVGDVSSSTIATEVSEAECGTQSATtq----geNDWdwCCELCCNPACFGC 72  Yersinia enterocolitica
P31518       20 QETASRQFGDAFSTPIAAEVNKKACDTELPP--------SDW--CCEVCCNPACAGC 66  Yersinia kristensenii
P07593       20 QETVSGQFSDALSTPITAEVYKQACDPPLPPae----vsSDWd-CCDVCCNPACAGC 71  Yersinia enterocolitica
P74977       20 QETASMHLDDTLSAPIAAEINRKACDTQTPSpse---enDDW--CCEVCCNPACAGC 71  Yersinia enterocolitica
WP_014654027 20 QDAKP---AGSSKEKITLES--KKCNIVKKNnesspesmNSSnyCCELCCNPACTGC 71  Escherichia coli
WP_001353651 20 QSTES---LDSSKEKITLET--KKCDVVKNNsekksenmNNTfyCCELCCNPACAGC 71  Escherichia
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