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Chorismate pyruvate-lyase Rv2949c-like This domain is found in chorismate pyruvate-lyases (EC:4.1.3.40, also known as 4-HB synthase and p-hydroxybenzoic acid synthase) such as those found in Mycobacterium tuberculosis where it removes the pyruvyl group from chorismate to provide 4-hydroxybenzoate (4HB). The chorismate pyruvate-lyase encoded by sll1797 in cyanobacteria Synechocystis sp., has been shown to catalyze the initial and essential step in plastoquinone biosynthesis. In E. coli, the chorismate lyase (UbiC) catalyzes the conversion of chorismate to p-hydroxybenzoate and pyruvate in the biosynthesis of ubiquinone as well.
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Jiyao W et al.(2023). "The conserved domain database in 2023.",