Conserved Protein Domain Family
DUF63

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pfam01889: DUF63 
Membrane protein of unknown function DUF63
Proteins found in Archaebacteria of unknown function. These proteins are probably transmembrane proteins.
Statistics
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PSSM-Id: 426495
Aligned: 31 rows
Threshold Bit Score: 252.475
Created: 19-Apr-2021
Updated: 29-Sep-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Mboo_1961    2 ISDFLYKYYIDPVKYGEPYNIVETLTYAIILIIGVYLLYRWFSNSawlldhGIKLDSSFILATLPYVVLGGVLRVIQDTG 81  Methanoregula...
jgi:Arcve_0122   2 LWDFIKKYYIDSIVYKQGYNPVNTLTWALILVAAVILIYRTLKKY------DVKFDERFVAGNIPYVILGASVRVVEDAG 75  Archaeoglobus...
WP_015591141     3 IYEFIKKYYIDSLVYKQGYNIVNTLTFAIILILAVVAIYKYLSK-------RIKFDEKFVIANIPYILLGSSVRVVEDAE 75  Archaeoglobus...
Q57882          37 IKNFIYKYYIEPAEKGTGYNIVQEITYGIILALALYLFYKALRKL------NINIDEKFAIPGIVFTVLIALMRALVDCG 110 Methanocaldoc...
WP_011972741     7 ISGFINKYYINPIYNQSGYTIIQEITYGILLFVMVYIFYRACKSL------KIEIDSKFALTTVFYVILISLLRSMTDAG 80  Methanococcus...
WP_013181100     7 IDNFIYEHYIYPIEAGTGYNLVQEFTYGILLFVMVYLFYKIAQKF------QIEIDEKFAKVTIVYIILITLMRALVDAG 80  Methanococcus...
Q6M0E3           7 IREFIYRYYIYPIDTKQGYNLIQEITYGILLFVMVYTFYRMCLKL------KIAIDRRFAEVTVFYVILITLMRALVDAG 80  Methanococcus...
Q5JHD6           7 VIDFFYRYFWEPMFTRSGYNAVNTFVYALLFGLGVIYTYKWIIKPl-----KIPVDERLFWAVTPMVVFGATVRALVDGG 81  Thermococcus ...
Q5JH92           3 VGEFFYRYFVEPIKYNQGYNPVNTLVYAVILGIMVLLLYRILKRM------GIRIDDRFFLSLMPYIVLGPLMRAITDEG 76  Thermococcus ...
Q8TZI0           2 IREFFQKYFIDPIKYNTGYNPVNTLVYAIILGIATLLVYKVLKRL------KIEINNAFFRALIPYMIFGAFTRALTDAG 75  Pyrococcus fu...
jgi:Mboo_1961   82 MVGGDWQYLIVTPPIYFVLFFFTLAMIFIGGTLkkngLIKDFLSFYAFIGCMSVFVVSLILLswgMAHAHVDLFILAIIL 161 Methanoregula...
jgi:Arcve_0122  76 FLNPPVSYFFMTPLIYVVIFCIAFPTLVLSIRL----RGERYWIHYGMLGLVLSCGVLVLLF---SNLEVVNAWILPSTI 148 Archaeoglobus...
WP_015591141    76 FLKPPISYFFMTPFIYIVIFLIAFPTLVISLR-----KKEDYWKYYAAVGVFLSAAVLAMLF---SSLEVIHGWLIPVTL 147 Archaeoglobus...
Q57882         111 YI--ERSFLTITPGIVFLIGGFFILTILTTGLV----FKEKYYKASAVIGLILLLYFLFVFL-----QHITHLEAILYVG 179 Methanocaldoc...
WP_011972741    81 VL--PHTFYTVTPGIVVVLGIYYIFSIILTGYF----FKEKYYKYSIIMAVLPMLYFGAIFL-----TNIVYFGTLLQIL 149 Methanococcus...
WP_013181100    81 VI--ERLFFTVTPGIVILIGAYYLLSLIISGAL----LKKKYYIGSIVMAVIPILYFLYEFV-----QRIVHIEALTLVA 149 Methanococcus...
Q6M0E3          81 LF--PRLYYTVTPGIVVAVGIYYMLSIIISGIL----LKKRYYLLSIAMAVVPILYMLFEFS-----SRITHPEAIVYVS 149 Methanococcus...
Q5JHD6          82 VL--PQHPLILTPGIFFTAFFLILPAIYADSKL------GMYPKITVAWGTILALWANYLLV-----THAKNWEPYELTL 148 Thermococcus ...
Q5JH92          77 LL--PRTYLTVSPGGYFVIAAFAIASLFAVWRHl--gPDERLYPIYRDFGWVLVGGLVFIIIi-nWGKLSVRWEYFKYFI 151 Thermococcus ...
Q8TZI0          76 VF--PRTYLTVSPGIYFLVFVIAFSALLVSHKF-----AKDWRGVFLWFGWGLVMVDLAAMSa-nISKINFDFAVLKYFI 147 Pyrococcus fu...
jgi:Mboo_1961  162 LMALAATVLVWGFMRYILs--WEYVQDPLYIALIFGQMLDASATSYGLTFhpaVHYIEQHVVGSNLIAMTGTAFVMYPLK 239 Methanoregula...
jgi:Arcve_0122 149 ILASLFCSAYRLLTSKFY----SPMSNLLSYMVFFSHMVDGWATFFGIQF---LGYWELHVLPRFLISTFG-PWIMIPAK 220 Archaeoglobus...
WP_015591141   148 TAAFLFAAAYHFLTRKFY----PKMHNGLSDLVFFSHMVDGFATFLGIQF---LGYWELHVLPRFLIDTFG-AWVMVPSK 219 Archaeoglobus...
Q57882         180 ILVGIFYYLVKFLDKTLK---LNIIQSKIDDYVVIGQLIDASATTIGIGV---YGYWEQHPIPRFLMETFG-VYAFIPFK 252 Methanocaldoc...
WP_011972741   150 LIIAIIYGIISYLLNNVEyikNKLKFDKIDKYAILGQLTDASATAVGIAS---HGYWEQHPIPRFFMDTFG-AYSMIPLK 225 Methanococcus...
WP_013181100   150 LILAISYILAIFILTKIK----KSKIEKLDKYTIFSQLVDASATSVGIAI---YGYWEQHPVPRFFMDLMG-PYVMIPLK 221 Methanococcus...
Q6M0E3         150 GILVLSYYLLIYIVEKLK----KAKIERIDKYAIFSQLVDASATSVGIGV---FGYWEQHPVPRFFMDYFG-PYSIIPLK 221 Methanococcus...
Q5JHD6         149 IHTAVSFAAVFIFYRWRP-------FDRLYLYPVLAHYFDVASTVVAIHF---YGYREVHWIENHLVNWFG-AYIYYPWI 217 Thermococcus ...
Q5JH92         152 PSLAVSEAFIWALAKKFK-------LIVDNKVLFYTHFYDATTTFVGIQF---FGFWEQHVLARTLIDLTGTPAVMYLEK 221 Thermococcus ...
Q8TZI0         148 PFLILAELVVFLLSKKVS-------LVRENSYLFYAHFYDATTTFVGVDF---MGYWEQHVLPRLLIGLTGTAAVMYVLK 217 Pyrococcus fu...
jgi:Mboo_1961  240 LVILFPAIYIMQLYRKEANAt-FWHLVLLAMIVVGLAPGIRDMIRMVLYV 288 Methanoregula boonei 6A8
jgi:Arcve_0122 221 VIVFAAILYVLDSSRDEEDTe-LINFVKFVLIVLGLAPGLRDALRMTFQV 269 Archaeoglobus veneficus SNP6
WP_015591141   220 IIVFLAVLYILDTSEDDIH---FVNFIKFVLVVLGLAPGMRDALRMCFAt 266 Archaeoglobus sulfaticallidus
Q57882         253 LLIILLALYILNKEVEDEN---IKNIIKLCIMALGLAPGLRDLFRTVMGV 299 Methanocaldococcus jannaschii DSM 2661
WP_011972741   226 LALVFSVLYVLNHEVDNKN---LRNIIKITIMALGFAPGLRNLFRIVMGV 272 Methanococcus aeolicus
WP_013181100   222 LIVVVLVLELFNREVENKN---LRNILKIAVLSLGLAPGLRNLFRTIMGV 268 Methanococcus voltae
Q6M0E3         222 MLVVLLVLDIFNKEVKDDN---LRNILKITVMALGLAPGLRNLFRTVMGV 268 Methanococcus maripaludis
Q5JHD6         218 TLILVVVYYALKELVTDEE---ERRFWYLAIYILGLGPAIRDPAQMILQl 264 Thermococcus kodakarensis KOD1
Q5JH92         222 LLVLIPVVYILDRMMEDEDPe-LINFVKLAIFVLGFGPGTRNLLIALLg- 269 Thermococcus kodakarensis KOD1
Q8TZI0         218 FIILFAAVWLLKELEKEGEEkeLLDFIKMVIFILGFAPGTRNLLRMLMGV 267 Pyrococcus furiosus
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