1C5A,6JV7


Conserved Protein Domain Family
ANATO

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pfam01821: ANATO 
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Anaphylotoxin-like domain
C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to a three-fold repeat in fibulins.
Statistics
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PSSM-Id: 426455
Aligned: 101 rows
Threshold Bit Score: 24.9227
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1C5A_A        21 CCYDGAYR-NDDETCEERAARIkI-GPKCVKAFKDCC 55   domestic pig
CAF96111       4 CCQDGRNRgNNGHDCTIIPAF--SsSYTCRIAQEQCC 38   spotted green pufferfish
XP_015208786  28 CCRNGRDWaTQKQDCSTLPLM--SeLPTCRIAQEQCC 62   spotted gar
XP_003221476  33 CCTHGYEWaSQKRDCSSLPLN--PdSKECSIAQEQCC 67   green anole
XP_005994038  32 CCTQGQEWaTRTRVCSSLPFV--SdVQECRFAQQQCC 66   coelacanth
AAC05388      33 CCDKGVEWaNKNRICTSLPLI--SeSRECSMTQVQCC 67   chicken
XP_018875987  15 CCAAGQQWaIDNDECLEIPESG-TeDNVCRTAQRHCC 50   western lowland gorilla
Q08879        36 CCTDGNQMaNQHRDCS-LPYT--SeSKECRMVQEQCC 69   house mouse
PNI48493      44 CCADGHRMaTHQKDCS-LPYA--TeSKECRMVQEQCC 77   chimpanzee
EHB13219     141 CCADGQQMaIQHRDCS-LPYA--SeSKECRMIQEQCC 174  naked mole-rat
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