2FP1,2GTV,3NVT,5GO2,6AL9,3HGW


Conserved Protein Domain Family
CM_2

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pfam01817: CM_2 
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Chorismate mutase type II
Chorismate mutase EC:5.4.99.5 catalyzes the conversion of chorismate to prephenate in the pathway of tyrosine and phenylalanine biosynthesis. This enzyme is negatively regulated by tyrosine, tryptophan and phenylalanine.
Statistics
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PSSM-Id: 460345
Aligned: 775 rows
Threshold Bit Score: 44.0211
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2FP1_B            3 TSQL----AELVDAAAERLEVADPVAAFK--WRAQlPIEDSGRVEQQLAKLGEDArsqhIDPDYVTRVFDDQIRATEAIE 76  Mycobacteriu...
WP_012234381     11 RRQLteldQEILRSIERRARIAHELAKLRtgTARFaPTADAAHVQALERAVTPp-----FPQRAVRPIFVAIDAASRAFE 85  Sorangium ce...
WP_013661758     15 sawaddvsSELIHSISERLSYMEDVALYK--AQKHvPIEDVAREKLVVDESKMSAkesgLDPESIEAFFRAQISVAKAIQ 92  Marinomonas ...
Q74NC4          244 RKQImvidKLILDLIKIRNDLAKQIKEIKe-LRNL-PIEDKKWEIEKRNILLEFAkereLNPLYTDQLIELLISWAKHIE 321 Nanoarchaeum...
jgi:Theth_0487  263 RYAIsvidEVILRLIEKRVEIAKKIAIKKm-ELQE-TIENTEVEEEKLAKIARkt---kLNSWEVEKIFRQIMDVTKAEE 337
jgi:Arcve_0433  270 RGYIravdSLILRLLERRTQAGRKIALHKr-DRNE-PIEIADLEEVKIKDLLLrt---sLNPIYVQDIFENIMGLTKEEE 344
jgi:Arcpr_1546  270 RGYIraldSLILRLIERRVETGKKVAEIKk-ERNE-PIEITDVEEIKIRDLIAnt---hLNPVLIYRIFDSLMTLTKEEE 344
CGB:Asulf_00975 280 RGYIrvvdSLILRLIERRVRAGKEIAMYKk-EKNL-PIEISEIEEVKLKELASst---tLNRMMLNRIFGEIFHLTKAEE 354
WP_012966713    270 RGYIktvdSLILRLIEKRVDAGRRIALEKm-KRNE-PIEVSEVEYFKLKELTSkt---sLDAGSVSSIFEEIMSLTKAEE 344 Ferroglobus ...
O30012          270 RGLIksidSLILRLIERRIDAARQIARIKm-ERGE-PIELKDVEEEKLWEVMSkt---tLNPVKLKEIFEGIMSLAKEEE 344 Archaeoglobu...
2FP1_B           77 Y 77  Mycobacterium tuberculosis
WP_012234381     86 v 86  Sorangium cellulosum
WP_013661758     93 Y 93  Marinomonas mediterranea
Q74NC4          322 N 322 Nanoarchaeum equitans
jgi:Theth_0487  338 Y 338
jgi:Arcve_0433  345 Y 345
jgi:Arcpr_1546  345 Y 345
CGB:Asulf_00975 355 Y 355
WP_012966713    345 Y 345 Ferroglobus placidus
O30012          345 Y 345 Archaeoglobus fulgidus
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