2GKS,3CR8,1V47


Conserved Protein Domain Family
ATP-sulfurylase

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pfam01747: ATP-sulfurylase 
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ATP-sulfurylase
This domain is the catalytic domain of ATP-sulfurylase or sulfate adenylyltransferase EC:2.7.7.4 some of which are part of a bifunctional polypeptide chain associated with adenosyl phosphosulphate (APS) kinase pfam01583. Both enzymes are required for PAPS (phosphoadenosine-phosphosulfate) synthesis from inorganic sulphate. ATP sulfurylase catalyzes the synthesis of adenosine-phosphosulfate APS from ATP and inorganic sulphate.
Statistics
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PSSM-Id: 426407
Aligned: 165 rows
Threshold Bit Score: 67.9486
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2GKS_B         145 PEYRKTPKQVREEIKSLGLD-K----IVAFQT-RNPMHRVHEELTKRAMEkvGGG--------LLLHPVVGLTKPGDVDV 210 Aquifex aeolicus
ACL03397       173 RRLRHTPQEIRTLFKKLGWR-S----VVAFHT-EKVLHRPDYEQTIRAMAhaRAN--------LLLHPVIGRIRPGDMDT 238 Desulfatibaci...
jgi:Dole_1013  172 RQLRKSPAEVRELYRKLSWH-R----VIGFHT-RQPVHRLQFEMTIRAMRtaRAN--------LLCLPSVGTIDPDDVDH 237 Desulfococcus...
WP_014956369   165 KQIRNTPAEVQKTFAKLGWK-R----IVGFQT-RQPIHRPQFEMTIQAMQkaRAN--------LLLLPIAGVTKPGDFDH 230 Desulfobacula...
WP_004071574   166 KQIRNTPSEVRQQFCKLGWK-R----IVGFQT-RQPIHRPQFELTIQAMKkaKAN--------LLMLPIAGIPRPGDFDH 231 Desulfobacter...
IGS:B005_2854  114 RELRVTPAEVR---AQRELDpTahqpLLAVVT-DRPLH--HRALHQIRAEadALGrdggraevLVVI---------DAPL 178 Nocardiopsis ...
WP_012081970   141 EDVKKAKEEIAKRKKELKAK-E----VSAIMLaAKPLHRAHERLIRSTLE--HSD--------LVVLFLLKPYVNDQFSY 205 Nitratiruptor...
jgi:Nitsa_1667 141 plIRDTVNRIRQMIRRTGAQ-K----ISAMMLaANPLNRAHERIIRQILT--RAD--------LVVLFLRKPFTDEGLRY 205 Nitratifracto...
Q7M820         141 eDVKEVKRKIKEAQEAIGAK-H----TAALMLsAKPLHRGHERIIRLTLD--ETD--------LLVLFLLKPYRTDIMDY 205 Wolinella suc...
WP_012857474   142 ddikqiKTNIQEAKKELDAK-N----VAAIMInANPFHRAHERVIRMTLE--KYD--------LLVIFLLKPYKQDILSY 206 Sulfurospiril...
2GKS_B         211 YTRMRIYKVLYEK-YYDKK-KTILAFLPLAMRM-AGP-------REALWHGIIRRNYGATHFIV---GRDHASPGKdskg 277 Aquifex aeolicus
ACL03397       239 YTRVRCYLAACQK-YSPGS-MITLSLLPYTMRY-AGP-------REALLHAIIRKNFGCTHFIV---APCHAGPEVdesc 305 Desulfatibaci...
jgi:Dole_1013  238 YTRVRCYKRVAER--YPPD-SFLLNLVPMAMRM-AGP-------REALLHLIVARNFGCSGFII---GPDHASPPHpdng 303 Desulfococcus...
WP_014956369   231 FTRMRCYQKVAAH--YPPD-TYVLNLLPLAMRM-AGP-------REAILHMIIGKNFGCTHFVI---GHDHASPGNdsgn 296 Desulfobacula...
WP_004071574   232 YTRMRCYQKVAAY--YPPD-TYMLNLLPLSTRL-AGP-------RDAVLHMIIGKNFGCTHFVI---GHNHATPGSdscg 297 Desulfobacter...
IGS:B005_2854  179 EDEGAASAVLAAEpLLPPRsVFVVATLPRSSRRgSGPfggewteRDAALAAHVAAAYGATHMLLeagGRGPE-------- 250 Nocardiopsis ...
WP_012081970   206 ELRYKTVDYFVKN-YLPKN-RVITVPLENTYIF-AGF-------NELILDAIVAQNFGCTRLVV---GKNHAGLGL---- 268 Nitratiruptor...
jgi:Nitsa_1667 206 DIRHNAVQLFIDN-FLPRN-KVLVVPFENTYIF-AGY-------NELVLDALLARNAGCNELVI---GKNHAGLGL---- 268 Nitratifracto...
Q7M820         206 SLRHKTLEYLVEN-YLPKS-RVLIVPLEDTYLF-AGG-------NEMILDAIVAQNLGCDKLVT---GANHAGLSM---- 268 Wolinella suc...
WP_012857474   207 DLRLKSLQYFVDN-YLPKN-RVVIVPFENTYLF-SSY-------KNAILDSICASNYGCNKLIL---GQHHSGIGA---- 269 Sulfurospiril...
2GKS_B         278 kpFYDPYEAQELFK-KYEDEIGIKMVPFEELVYVPELDqyveinEA-K-----KRNLKYINISGTEIRENfLKQGRKLPE 350 Aquifex aeolicus
ACL03397       306 taFYDPDAAFSLAA-SYAGELNLSVLQFEDLVYVEEDGayvpkkE--------ANGRKIRSMTEEEFIKR-IQDGKKAPE 375 Desulfatibaci...
jgi:Dole_1013  304 vaFYEKDRACRLLE-THAGELGMEVIVFNEIVYLPFEDefvpvdQV-------ADGTQYVSMPGSLIRRR-MRAGKTVPD 374 Desulfococcus...
WP_014956369   297 tpFYKYDEAIELTR-EITRELNVETVTFKEMVYLPFEDeykiagQV-------PKNTDTISFNGTDIQKR-IRNGKRVPD 367 Desulfobacula...
WP_004071574   298 npFYDTPQVRALAE-QAGEEIGIEPVFFEEMVYLPFEDefklasEV-------TDGQETLSFTNDHIRDR-VRKGKHIPE 368 Desulfobacter...
IGS:B005_2854  251 --------VERVMAlR----PPVTVLDPEPWRYDSGEElwkp-------ftsvDPGRARREPSDDEVENE-LAHGRELPS 310 Nocardiopsis ...
WP_012081970   269 --YYDKNSLKSVFD-NLKG-INIQIEMVNEFVYCDKCK------TLvStetcpHGSHHHISYHADSILEL-LKLGLLPPA 337 Nitratiruptor...
jgi:Nitsa_1667 269 --YYDQNRLNTIFD-TLSG-LDLEITTVDEYVYCDTCR------TLvStetcpHGQHHHIHYHSESIMTL-IQNGILPPP 337 Nitratifracto...
Q7M820         269 --YYDRNQMRSIFD-TLKG-IDIDIKIMSEFVYCNMCR------TLvStktcpHGHHHHITYHSDSIFEF-FRLGLLPPA 337 Wolinella suc...
WP_012857474   270 --YYDKNEMKSVVN-QYND-LDIEIEIIAEFVYCDECK------TLvStstcpHGAHHHIKYHAKSLLEI-LKLGMLPPA 338 Sulfurospiril...
2GKS_B         351 WFTRPEVAEILAE 363 Aquifex aeolicus
ACL03397       376 WFTFPEVAKEMER 388 Desulfatibacillum aliphaticivorans
jgi:Dole_1013  375 WATFPEVLEELER 387 Desulfococcus oleovorans Hxd3
WP_014956369   368 WATFPEVIQELQK 380 Desulfobacula toluolica
WP_004071574   369 WASFPDVIKELRR 381 Desulfobacter postgatei
IGS:B005_2854  311 WFTPARVGAELAR 323 Nocardiopsis alba ATCC BAA-2165
WP_012081970   338 VLVRKEISAILLS 350 Nitratiruptor sp. SB155-2
jgi:Nitsa_1667 338 ILVRKEISANILa 350 Nitratifractor salsuginis DSM 16511
Q7M820         338 VLVRKEISAIILS 350 Wolinella succinogenes
WP_012857474   339 IFMRKDISAMLLS 351 Sulfurospirillum deleyianum
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