3QD7,2ZQE


Conserved Protein Domain Family
Smr

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pfam01713: Smr 
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Smr domain
This family includes the Smr (Small MutS Related) proteins, and the C-terminal region of the MutS2 protein. It has been suggested that this domain interacts with the MutS1 protein in the case of Smr proteins and with the N-terminal MutS related region of MutS2. This domain exhibits nicking endonuclease activity that might have a role in mismatch repair or genetic recombination. It shows no significant double strand cleavage or exonuclease activity. The full-length Swiss:Q86UW6 also has the polynucleotide kinase activity.
Statistics
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PSSM-Id: 460303
Aligned: 565 rows
Threshold Bit Score: 35.135
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3QD7_X          51 NLLRQPVEECRKMVFSFIQQALADGLRNVLIIHGKGRddkshaNIVRSYVARW---LTEF--DDVQAYCTALPHHGGSGA 125 Escherichia c...
jgi:Spith_1734  65 DLHGFTREEAEIRLKAFLGEAQGKGYRVLLIVHGKGLhse-rePILKKVVYRT---LESC--PFVGRIETAPRRWGGAGA 138
Q3A2X6         143 DLHGATREDARQKVRYFLEDGVYQGYKTVLIITGRGKgsq-qgPVLRDDMEKY---LSREarAWVAEWGRAPARYGGEGA 218 Pelobacter ca...
Q74EE8         151 DLHGLTREEAVASLERFITGAHRRGQKAVLVITGKGNnss-gePVLQGAVLSW---LRERgkSMVAEFAPAPRDMGGSGA 226 Geobacter sul...
ACH37400       145 DLHGLTREEALENLDRFVKGAYNRGQKGVLVITGKGNnsa-gePVLKSAVAGW---LREKgkGMVSEFIQAPNDMGGSGA 220
jgi:Ppro_3354  151 DLHGLTREEALEALPRFLASAAAHGEKAVLVITGKGNnsp-vePVLQQAVLGW---LRDAgrKLVVEFAPAPREMGGSGA 226
WP_012468594   155 DLHGLTREEAVASLGPFLQAARNAGEKGVLVITGKGNhsl-egPVLQQVVAAW---LRDQgrELITEYAPAPAEMGGSGA 230 Geobacter lov...
XP_002498372   100 DLHGLYVKEAQWILKKRIYATIQQGDPQIRVIVGKGLhsphgiAKLKPAVEELcdeARLK--NYI--------DPHNAGV 169
EMG50563       102 DLHGLYVKEAEWILERRIYHAVNTQQSHLNVIVGKGLhsangvAKIKPAVDELcdkVRLN--HYI--------DPKNAGV 171
XP_004199558    99 DLHGLFVKEAEFFLQTRIAAEVQRSSSHLKVIVGKGLhsqngiAKLKPAIDQMcteSRLK--HYI--------DKDNTGV 168
3QD7_X         126 CYVALR 131 Escherichia coli K-12
jgi:Spith_1734 139 VVAFLR 144
Q3A2X6         219 LVVFLR 224 Pelobacter carbinolicus DSM 2380
Q74EE8         227 VVVFLR 232 Geobacter sulfurreducens
ACH37400       221 VVVFLK 226
jgi:Ppro_3354  227 FVVFLR 232
WP_012468594   231 FVIFLR 236 Geobacter lovleyi
XP_002498372   170 LIIELK 175
EMG50563       172 LVIDLK 177
XP_004199558   169 LVIDLR 174
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