5L9K,5CB5,3EJF,1HJZ,2DX6,1YD9,2XD7,5M3I,2X47


Conserved Protein Domain Family
Macro
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pfam01661: Macro 
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Macro domain
This domain is an ADP-ribose binding module. It is found in a number of otherwise unrelated proteins. It is found at the C-terminus of the macro-H2A histone protein. This domain is found in the non-structural proteins of several types of ssRNA viruses such as NSP3 from alphaviruses. This domain is also found on its own in a family of proteins from bacteria, archaebacteria and eukaryotes.
Links
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Statistics
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PSSM-Id: 426372
Aligned: 85 rows
Threshold Bit Score: 77.2178
Created: 19-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5L9K_B  49 VNAANGSLLGGGGVDGAIHHAAGPELLKAC-QEMr---NnelngeeLPTGEVIITSGFQLPs-rFIIHTv--gPIWNq-- 119 Oceanobacillus iheyen...
2DX6_A  20 VNAANNYLKLGAGVAGAILRKGGPSIQEEC-DRI----Gk------IRVGEAAVTGAGNLPv-rYVIHAav--------- 78  Thermus thermophilus HB8
Q9YBE9  27 VNPANSLMIMGGGAAGALKRAGGSVIEEEA-MRK----Ap------VPVGEAVITSGGSLPa-rFVIHA----PTMEe-- 88  Aeropyrum pernix K1
P9WK29 208 tNAANTRLRHAGGVAAAIARAGGPELQRES-TEK----Ap------IGLGEAVETTAGDMPa-rYVIHA----ATMEl-- 269 Mycobacterium tubercu...
O67112  19 VNPANSRGLMGGGVAVVIKRLGGEEIEREA-VEK----Ap------IPVGSAVLTTAGKLKf-kGVIHA----PTMEe-- 80  Aquifex aeolicus VF5
Q8TWT2  32 VNPANSRGVMGGGVAAAIKAKGGEEIEREA-MEK----Al------IPVGEAVETTAGDLDa-eYVIHA----PTMEr-- 93  Methanopyrus kandleri
Q8ZN14  44 VSAANSFGLMDGGVDAAITAYFGPQLQERVqQHIlreyLg-----eQPVGTAFVIETGNSKy-pWLVHA----PTMRvpl 113 Salmonella enterica s...
Q5KUT6  19 CNAANGIGPMGGGVAAAIHRAGGRVIEEEA-IRVcqaqDp-------QPGDLYVTGAGSLPf-rGVIHL----VTMKq-- 83  Geobacillus kaustophilus
Q5V4P3  19 VNAANTSLRMGSGVAGALKRAAGSGLNDEA-VAK----Gp------VDLGGVATTDAYDLDa-eYVIHAaampP------ 80  Haloarcula marismortui
Q5KV84  18 VNTVNCVGVMGKGIALQFKQAYPEMFSEYE-KACrr--------keVQPGKMHVVSTKSLLnpkYIINF----PTKRh-- 82  Geobacillus kaustophilus

5L9K_B 120 --TPDLQEELLANCYRNALEL-----VKVKKLSSISFPSISTGVYGYPIHEAAAIA 168 Oceanobacillus iheyensis HTE831
2DX6_A  79 lgDEPASLETVRKATKSALEK-----AVELGLKTVAFPLLGTGVGGLPVEAVARVx 129 Thermus thermophilus HB8
Q9YBE9  89 -pGMRIPLVNAFKASYAALRL-----ASEAGIESVAMPAMGAGVGGLSVAEVAREA 138 Aeropyrum pernix K1
P9WK29 270 --GGPTSGEIITAATAATLRK-----ADELGCRSLALVAFGTGVGGFPLDDAARLM 318 Mycobacterium tuberculosis H37Rv
O67112  81 -pAMPSSEEKVRKATRAALEL-----ADKECFKIVAIPGMGTGVGGVPKEVAARAM 130 Aquifex aeolicus VF5
Q8TWT2  94 -pAQRIGVENVREATEAALRK-----AEELGVESVAFPGMGTGVGGVPYEDAAETM 143 Methanopyrus kandleri
Q8ZN14 114 iiDGTDAVYNATRAALLAIFQhnksaGEDRKIKSVVFPAMGAGCGQVSPGSVARQM 169 Salmonella enterica subsp. enterica serovar T...
Q5KUT6  84 -pAGATSYEIVRSCLERLVAH-----CREHGIKKVALPALGTGVGRLDKARVARLF 133 Geobacillus kaustophilus
Q5V4P3  81 --GGQSTAESIRNATRNALAE-----ADALNCESVVFPAIGCGIAGFDFEEGIRII 129 Haloarcula marismortui
Q5KV84  83 -wKNKSRMEDIELGLADLIKV-----VKELNIKSIALPPLGCGNGGLRWDEVRPKI 132 Geobacillus kaustophilus
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