6U7H_B        580 ANLSIPSNWTISVQVEYLQ----ITSTPIVVDC-----------STYVCNGNVRCVELLKQYT--SACKTIEDALRNSAR 642  Human coronav...
ADN95979      701 GYASTPIYSGYLTHTEVISkppfCTSFTSLPSC-----------AELICGSNSLCYTKLTEFGklNMCTALGDAISV--- 766  Fathead minno...
APG77354      430 NDYCFTDSFTPAVKLITVP----RIQPIESLSCqnlcrgqsstsSQTLCTTAELSSPLMQQCY--SIVAQIRKL--SGSK 501  Xinzhou toro-...
ASF90450      587 SFVELALDHVLVSESEYFQ----TEMPVFDIDC-----------EKYICDNSESCRMLLEQYA--GFCSKITSDVKGNSQ 649  Wencheng Sm s...
APU57645      580 QQIELPIDHYVSVKEQFIQ----TSTPKFDVDC-----------ERYICDVSSDCRELLVKYG--GYCSKILADIKSSSI 642  Lucheng Rn ra...
AQW43023      573 QIVSLPLDHVINVKEQFVQ----TSAPKFDVDC-----------ERYICDVSVQCKELLAKYG--GYCPKIVSDIKSSSL 635  Coronavirus A...
ABN10848      777 FTAAIPTNFSFSVTQEYIE----TSIQKVTVDC-----------KQYVCNGFTRCEKLLVEYG--QFCSKINQALHGANL 839  Bat coronavir...
AHY61337      745 FVVEIPTNFSFGVTQEYIQ----TTIQKVTVDC-----------KQYVCNGFAKCEQLLREYG--QFCAKINQALHGANL 807  BtVs-BetaCoV/...
YP_009072440  757 STLQIPINFTIGIEYETIP----VTMPKVTVDC-----------AQYVCGDNSECRTLLVQYG--TFCETINDALRGVAL 819  Bat Hp-betaco...
P59594        692 NTIAIPTNFSISITTEVMP----VSMAKTSVDC-----------NMYICGDSTECANLLLQYG--SFCTQLNRALSGIAA 754  Severe acute ...

6U7H_B        643 LESADVSEMLTFDKKAFTLANVSSFG-DY-----NLSSVIPS--LPTsgsrvaGRSAIEDILFSKIVTSGLGTVDAdYKN 714  Human coronav...
ADN95979      767 -----------------------------------------------------YNSVITDIVESQATLDAL------Y-- 785  Fathead minno...
APG77354      502 FKGNEFIPTSQIVNR-TTFRTIKDFDpKLfvsniKIQTFK-------------THNQISDRLR--------------IFQ 553  Xinzhou toro-...
ASF90450      650 LLNANTLAMYKNIVPSDSIKPIENFG-DF-----NMSMFIDK--S--------GRSVLEDLLFDKIVTTGPGFYED-YYK 712  Wencheng Sm s...
APU57645      643 QLDYQILGLYKTLAVDFKVP-------DIdfgdfNFSMYMSE--AN-------GRSFIEDLLFDKIVTTGPGFYQD-YYD 705  Lucheng Rn ra...
AQW43023      636 QLDYQVQGIYKTLNVDVKVPD-VDFGa------fNFSMFESE--PN-------GRSFIEDILFDKIVTTGPGFYQD-YYD 698  Coronavirus A...
ABN10848      840 RQDESVYSLYSNIKTTSTQTLEYGLNgDFnltllQVPQIGGS--SSS------YRSAIEDLLFDKVTIADPGYMQG-YDD 910  Bat coronavir...
AHY61337      808 RQDESIANLFANIKTEATQPLDAGLNgDFnltllQVPKVVTS--EYS------YRSAIEDLLFNKVTIADPGYMQG-YDE 878  BtVs-BetaCoV/...
YP_009072440  820 QQDVNQKDVFSSVRRLAKVSSPMNLGnln---gfNFSSILNQeaINGnn--fqARSAIEDLFFDKIETADVGFQKK-YDE 893  Bat Hp-betaco...
P59594        755 EQDRNTREVFAQVKQMYKTPTLKYFGg-F-----NFSQILPD--PLKp----tKRSFIEDLLFNKVTLADAGFMKQ-YGE 821  Severe acute ...

6U7H_B        715 CTK-G-LSIADLACAQYYNGIMVLPGVADAERMAMYTGSLIGGIALGGLT----SAVSIPFSLAIQARLNYVALQTDVLQ 788  Human coronav...
ADN95979      786 ------TEMLDVAMTKF--------GTVAQTRKKRFVEFIALGVASVALVe---ATVAIGLAVANANDIRELRGDVKNLR 848  Fathead minno...
APG77354      554 HM----FDVSDPSYGQY-----AVP-------VGDSWSNILGVFKEGMYNqdrdMSYMAAFPWLTAWRF---GRQINALS 614  Xinzhou toro-...
ASF90450      713 CRT---TTVKDLVCAQYYNGIMIIPPIQDAETIGMYGGIVAAGMTMGLFGg---QATMGTWQIAMSARLNAVGVTQGMIM 786  Wencheng Sm s...
APU57645      706 CKK---MNLQDLTCKQYYNGIMVIPPVMDDTLITFWSSAVAGSMTAGLFGg---QAGMVSWTVALAGRLNALGVMQDALV 779  Lucheng Rn ra...
AQW43023      699 CKK---MNLEDITCKQYYNGIMVIPPVMDDTLITFWSSAVAGSMTAGLFGg---QAGMVSWSIAVAGRLNALGVMQDALV 772  Coronavirus A...
ABN10848      911 CMKqGpQSARDLICAQYVSGYKVLPPLYDPNMEAAYTSSLLGSIAGAGWTaglsSFAAIPFAQSMFYRLNGVGITQQVLS 990  Bat coronavir...
AHY61337      879 CMKqGpPSARDLICAQFVAGYKVLPPLYDPNMEAAYTSSLVGSILGAGWTagasSFAAIPFAQSVFFRMNGIGITQQVLS 958  BtVs-BetaCoV/...
YP_009072440  894 CTG-G-SVVKDLGCAQSFNGLMVLPPQMTDAHVAAYTTSAALG-----------SFFSIPNTMQMAYRFNGIAVTQKVLV 960  Bat Hp-betaco...
P59594        822 CLG-D-INARDLICAQKFNGLTVLPPLLTDDMIAAYTAALVSGTATAGWTfgagAALQIPFAMQMAYRFNGIGVTQNVLY 899  Severe acute ...

6U7H_B        789 E----NQKILAASFNKAMTNIVdaftgvndaitqtsQALQTVATALNKIQDVVNQQGNSLNHLTSQLRQNFQAISSSIQA 864  Human coronav...
ADN95979      849 DesaaNFKAIEEKHNAFVKTTA--------------DGFAAQNEVNKGFNSNIDTLQNSLKDMAIVTSQKFKELDQAIQS 914  Fathead minno...
APG77354      615 Y----SISTLMQAYDGLVADLN--------------TNLMVLQNAIKQSADQVVLNSRYINQLADTLSVFSHNTHQNLVA 676  Xinzhou toro-...
ASF90450      787 E----DVQKLANGFNTLATSVS--------------KMASVTADALSRIQGVVNANALQVELLARATMDNFGAISSNFEI 848  Wencheng Sm s...
APU57645      780 E----DVNKLANGFNNLTQYVS--------------DGFKTTSQALSTIQAVVNNNAQQVSQLVQGLSENFGAISNNFAL 841  Lucheng Rn ra...
AQW43023      773 N----DVNKLANGFNNLTQYVA--------------DGFKTTSQALSAIQSVVNNNAQQISQLVQGLSENFGAISNNFLV 834  Coronavirus A...
ABN10848      991 E----NQKLIANKFNQALGAMQ--------------TGFTTSNLAFSKVQDAVNANAQALSKLASELSNTFGAISSSISD 1052 Bat coronavir...
AHY61337      959 E----NQKQIANKFNQALGAMQ--------------TGFTTTNLAFSKVQDAVNANAQALSKLASELSNTFGAISSSISD 1020 BtVs-BetaCoV/...
YP_009072440  961 D----NQKQIANKFNQAMMSVQ--------------TGFKATSSALEKLQKVVNDNAQALNNLVAQLTNNFGAISSAIND 1022 Bat Hp-betaco...
P59594        900 E----NQKQIANQFNKAISQIQ--------------ESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLND 961  Severe acute ...

6U7H_B        865 IYDRLDPPQADQQVDRLITGRLAALNVFVSHTLTKYTEVRASRQLAQQKVNECVKS-QSKRYGFCGN-GTHIFSIVNAAP 942  Human coronav...
ADN95979      915 LVSSINSLQLKLDTEIQLSANSDSALARVLTALSLGHRTNRNLDRHISQVRTCLASiQQNSLAGCVNqGSNSIPLGIRVF 994  Fathead minno...
APG77354      677 LNLHLSTVE-------YMSAKLSQFSIVLASLENALLDYKIQLQLLNQRTENCNRG-VESCMPFP---GIYLAHQRLDTP 745  Xinzhou toro-...
ASF90450      849 IEKRLKQVQAEQQMDRVINGKMNALLNFVSNYKLKVSELTSIQQLVKQKVQECVHA-QSLRNGFCGS-GLHVMSIPQLVP 926  Wencheng Sm s...
APU57645      842 IAERLERIEAAMQMDRLINGRMNILQNFVTNYKLSISELKSQQALAQSLINECVYA-QSSRNGFCGD-GLHLFSLMQRAP 919  Lucheng Rn ra...
AQW43023      835 IAERLERLEAQMQMDRLINGRMNILQNFVTNYKLSISELKSQQILAQSLVNECVYA-QSNRNGFCGD-GLHLFSLMQRAP 912  Coronavirus A...
ABN10848     1053 ILARLDTVEQDAQIDRLINGRLTSLNAFVSQQLVRSETAARSAQLASDKVNECVKS-QSKRNGFCGS-GTHIVSFVVNAP 1130 Bat coronavir...
AHY61337     1021 ILKRLDAVEQEAQIDRLINGRLTSLNAFVAQQLVRSETAARSAQLASDKVNECVKS-QSKRNGFCGS-GTHIVSFVINAP 1098 BtVs-BetaCoV/...
YP_009072440 1023 ITQRLDKLEADAQIDRLINGRLQVLQTFVTQQLIRASEIRASAKLAAQKMSECVQG-QSQRLDFCGR-GMHLMSFPQAAP 1100 Bat Hp-betaco...
P59594        962 ILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLG-QSKRVDFCGK-GYHLMSFPQAAP 1039 Severe acute ...

6U7H_B        943 EG-----LVFLHTVLLPTQYKDVEAWSGLCVDGT--NGYVLRQPNLALY-KEGn-----yYRITSRIMFEPRIPTMADF- 1008 Human coronav...
ADN95979      995 NEtgdlkIVFFYATRQRLGYLQFKATSAFCTNGT--LVTAAPGCIFTAN-GTQ----------IEHSKIGPLTPCGSSFv 1061 Fathead minno...
APG77354      746 SH-----HILLLSYMKPN-CEPSQIDMYYCQDNV--TYVAPYGCQFINR-ELE-------VIAPNATCDTPIKLLGCTY- 808  Xinzhou toro-...
ASF90450      927 NG-----VMFLHFSLVKNNSIIVKQTPGLCKEDKi-NCIVPKSGIFVSK-NDSn------WYITPRNKYVPKNITNSD-- 991  Wencheng Sm s...
APU57645      920 DG-----IMFFHYTLKPNNTIIVETTPGLCLSND--VCIAPKDGLFVRL-STArd---tdWHFTTRNRYSPEPITVNNT- 987  Lucheng Rn ra...
AQW43023      913 DG-----IMFFHYTLVPNNTIDVETTPGLCLGNN--VCIAPRDGLFVKT-NIRsd----vWHFTTRNLYNPQAITVNNS- 979  Coronavirus A...
ABN10848     1131 NG-----FYFFHVGYVPTNYTNVTAAYGLCNNNNppLCIAPIDGYFITNqTTTysv-dteWYYTGSSFYKPEPITQANS- 1203 Bat coronavir...
AHY61337     1099 NG-----LYFFHVGFVPTSFVNATAAYGLCNTENppRCIAPIDGYFVLN-STTtraadqeWYYTGSSFFSPEPITMANA- 1171 BtVs-BetaCoV/...
YP_009072440 1101 YG-----MVFLHVLYKPTDYINVTTVPAICSNDV---AYFPVDGVFVYY-NNS-------LMFTKRNYFEPEIITIDNI- 1163 Bat Hp-betaco...
P59594       1040 HG-----VVFLHVTYVPSQERNFTTAPAICHEGK---AYFPREGVFVFN-GTS-------WFITQRNFFSPQIITTDNT- 1102 Severe acute ...

6U7H_B       1009 -VQIENCNVTFVNISRSE-LQTI-VPE--YIDVNKTLQELSYKLpNYT---V-PDLV---VEQYNQTILNLTSEISTLen 1076 Human coronav...
ADN95979     1062 sLPIATCPTGSVDIEGVK--PSL-TPN--FEVPQLELKp--------------PKLE------VNLTNVNLSDYIRPItp 1116 Fathead minno...
APG77354      809 -NQTSLFMMSFVTRPFTK-LTPQeVPLh-IVNYTDQL----------------KPID---VEIFQANITTTLHEIKQI-- 864  Xinzhou toro-...
ASF90450      992 -IIFTTYSENFTVINNTIqFPGIeFPQ--DGDFDGQIKNVTLEL---------QSLK---DVVANMSYLDLSNHT----- 1051 Wencheng Sm s...
APU57645      988 -LTISG-GVNFTVVNSTI-DGIE-PPA--NPSFDEEFAELYKNV-TLEleqL-KNIS------FDPEMLNLTYYI----- 1048 Lucheng Rn ra...
AQW43023      980 -VIVNG-GVNFTSLNQTI-EGIE-PPT--IPSFDEEFEDLYKNI-TLEleqL-KNIT------FDPELLNLTYYI----- 1040 Coronavirus A...
ABN10848     1204 -RYVSS-DVKFDKLENNL-PPPL-LENstDVDFKDELEEFFKNV-TSH---G-PNFAe--ISKINTTLLDLSDEM----- 1267 Bat coronavir...
AHY61337     1172 -RYVSP-DTKYEQLDNKL-PPPL-LSNqtDQDFKEELEEFFKNV-SSQ---G-PNFQe--ISKINATLLDLSGEM----- 1235 BtVs-BetaCoV/...
YP_009072440 1164 -RSAGSCNVDVTYVNHTI-YNPE-MPE--LEDFKQELEEIRKNF-STGlpnR-PNFTlpgLEGINASMVDLSEEV----- 1231 Bat Hp-betaco...
P59594       1103 -FVSGNCDVVIGIINNTV-YDPL-QPE--LDSFKEELDKYFKNH-------TsPDVDlgdISGINASVVNIQKEI----- 1165 Severe acute ...

6U7H_B       1077 ksaelnytvQKLQTLIDNINSTLVDLKWLNRVET--YIK 1113 Human coronavirus 229E
ADN95979     1117 vd---lskiEDLQARFDKLNLTLTELSHISSSGS--GLP 1150 Fathead minnow nidovirus
APG77354      865 ---------QTLSEFVNNTDQAWLDN--VPEYGTpgWSI 892  Xinzhou toro-like virus
ASF90450     1052 ---------ALLKNISEEVKKMNITVSQFKQYVK--YVK 1079 Wencheng Sm shrew coronavirus
APU57645     1049 ---------DRLDELATNVSQLHVDVSEFNKFVQ--YIK 1076 Lucheng Rn rat coronavirus
AQW43023     1041 ---------DRLDELSTNVSQLHVDISEFNKYVQ--YIK 1068 Coronavirus AcCoV-JC34
ABN10848     1268 ---------AMLQEVVKQLNDSYIDLKELGNYTY--YNK 1295 Bat coronavirus HKU4-2
AHY61337     1236 ---------KILNEVVKQLNESYIDLKELGNYTY--YQK 1263 BtVs-BetaCoV/SC2013
YP_009072440 1232 ---------KILNDVVKELNASLINLQELGVNSQ--YIK 1259 Bat Hp-betacoronavirus/Zhejiang2013
P59594       1166 ---------DRLNEVAKNLNESLIDLQELGKYEQ--YIK 1193 Severe acute respiratory syndrome-related coronavirus