2LEM


Conserved Protein Domain Family
Apolipoprotein

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pfam01442: Apolipoprotein 
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Apolipoprotein A1/A4/E domain
These proteins contain several 22 residue repeats which form a pair of alpha helices. This family includes: Apolipoprotein A-I. Apolipoprotein A-IV. Apolipoprotein E.
Statistics
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PSSM-Id: 426264
Aligned: 92 rows
Threshold Bit Score: 50.3481
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2LEM_A         49 WDTLGSTVSQLQERLGPL--TR--D-FWDNLEKETDWVRQEM------NKDLEEVKQKVQPYLDEFQKKWKEDVELYRQK 117  house mouse
vbi:Avi_2239  946 IEQISDAASDADMRIELAlgNRmdT-IRAVYEESETRLSGTI------DAKLGALTETLGTADSRIEQAFGSKADQLRAV 1018 Agrobacterium...
5_pfamImport    1 --SLNAKGEEITNALSRG--RD--D-LIESLSNHGNDLVGRL------TQRGEAATADLAQASASVAQTLDQRLAEINAR 67  
AEB13456      312 tgtWTEKIESLEQDLKES--SE--N-FDSRLEDAVAGLDNSL------AEKTGALEDKINESAGTFENEFADKIKELSDI 380  Treponema suc...
7_pfamImport    5 TAEYEVKRAALEKQYDDAlvKRisElTKKTLEQEKKFQTALLsgqttiQEQINTVNQKIHDFIEQYRNEIQKTIENADEY 84  
Q92K98       1505 AAKVSETARQASDMLSTS--TRliEgKVDKLSDISSSTLSQIggivgrFEDHSKVLGQASDLLAAAQSNLVSTLEERQDA 1582 Sinorhizobium...
Q0W387       1006 ESELITKVSEVEASIAQQ--SR----EAKDLLKELEDTKETL------TSELENTRTSLMQELEETRSTVTREIQGTRTE 1073 uncultured me...
EGI62644     4933 EDRTVFIAIDTKDKLADI--AA--K-DIDKATHDLKAARDDV------VTKTKEVVDKVETSVADVGHDMKDIKDVAVIE 5001 Panamanian le...
8_pfamImport    6 TKKIGEKIEETSADVAQI--AK--D-TKDAVIKEIKDDTKLV------KGKLATSADAAAETADSAKEKMTKETKKAKEK 74  
9_pfamImport    6 TKKIGEKIEETSADVAHA--AK--D-IKDAVIKEVKDDTKLV------KGKLAAGADAATEAVDSAKEKVTKETKKAKEK 74  
2LEM_A        118 ASPQGAELQESARQKLQELQGRLSPVAEEFRDRMRTHVDSLRTQLAPHSEQMREs---LAQRLAELKSNPTLN--EYHSS 192  house mouse
vbi:Avi_2239 1019 YEEGQARLTQTLDSKVDQLSDVAAEADMRIEFALGSKVDSIRSVYEDSEARLAGt---IDAKLGQLIETVGFAdsRVQQA 1095 Agrobacterium...
5_pfamImport   68 LRDAQEALAADLGARGDSLSQRLAVVGAGIADTVSSRGDSLAARLEETSGRLHEv---VAVQGGALGDHLAEAgeRFSRM 144 
AEB13456      381 VENSTSRIEDECSGRISEIEEKLEQSSSGIQNKFSEKLSQIESYFNETSNSIEAg---YKERADSLQNELENKfsSLLET 457  Treponema suc...
7_pfamImport   85 LKTETDSYNERMNGQLDKIENDLNSKFENFREILLSKQESQSATIDAAVQEFTAwknsLKGKYEDASQQIEDQlkLLADT 164 
Q92K98       1583 LRTLSVGLVQR-SEEIERTMRALEGFVDGAFQRAEERSGQVAGNLRSGIQSSFSd---VGRLLSNTEQRATEAaeALRDT 1658 Sinorhizobium...
Q0W387       1074 VKHDIEETRSEVTREMEEVRTQVSAEVEDIRTTVKRELDDARSRTISDLDDIRNk---TITEIKDVSSSAVERveSVSAM 1150 uncultured me...
EGI62644     5002 AKEDANVIKEKLAAKAESISDSVEITKDKTTKEAKKAKEKASGFFSGIFKGSKHs---MDSAVDDVKEFLDETkkEAA-- 5076 Panamanian le...
8_pfamImport   75 TTSFFSGIFKGAKHAAEDVTDDVKEFLDETKKEAEMEEEHVKEKATASLKDLK-------------------------DK 129 
9_pfamImport   75 TTGFFSGIFKGAKHAVEDATDDVKEFLDETKKEAEIEEEHAKEKAA--------------ASLKDLKDKKDTAvsEVQET 140 
2LEM_A        193 AKSHLKSLGEKARPALEDLRHSLM 216  house mouse
vbi:Avi_2239 1096 LGSKADQIREAYEANHGRLAEMLD 1119 Agrobacterium vitis S4
5_pfamImport  145 IAERVSSARETLDQSGQSLVALFE 168 
AEB13456      458 FTKQAKIFEDKTSVFEDNVKQKSD 481  Treponema succinifaciens DSM 2489
7_pfamImport  165 NDQKINDLQKDFSVAANKATDVLD 188 
Q92K98       1659 LVKASDEAAASVEGVFSQAEERSR 1682 Sinorhizobium meliloti
Q0W387       1151 TIERIEDVSVKTTTQIENGRVEAV 1174 uncultured methanogenic archaeon
EGI62644     5077 --LEQTHVKEAAEAELKNLEHKTD 5098 Panamanian leafcutter ant
8_pfamImport  130 KDTAVSEVQETVDKAADRVKEAKD 153 
9_pfamImport  141 MDKAADRVKETKDKTAGKMKEAKD 164 
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