2EJA


Conserved Protein Domain Family
URO-D

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pfam01208: URO-D 
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Uroporphyrinogen decarboxylase (URO-D)
Statistics
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PSSM-Id: 426127
Aligned: 122 rows
Threshold Bit Score: 173.931
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2EJA_B         2 PKndlLLRSLRG-EPIGRFPVWLmrqAGRYMPEYRKIRNrVKNFLELCKNVDLATEISLLPLKILGVDAIIIF-----SD 75  Aquifex aeolicus
Q2NHN4         2 DLienLKAALNG-EEVEKVPAIS---ATAAAVEEAFPAA-NVSWPEAHKDAEQMARLGISLHEQAGLECARVP-----FD 71  Methanosphaera ...
Q2NHV3         4 NYtknLRDVLNG-KKTDIAPVVT---VTQSGILDAMERT-GTSWPQAHENPEQMATLGASLYELARLEDAKIP-----FC 73  Methanosphaera ...
Q8TII4         6 TSkerVFAMLNR-KPVDRVPVIT----GSVMVKEYIEKS-GSSWPDYHSNAEMMVNTVSLMHTDAGLDNIVMP-----FG 74  Methanosarcina ...
Q74AG9         2 TSferVMAAMGG-VETDRPPFTL------TLSLYGARLI-GASPEQYYTSPRLYAEGQDRVAELFGPDILFAP-----FA 68  Geobacter sulfu...
Q39S06         2 TAaerVMAVFTG-EKPDRPPFAL------TLSLYGARLI-NAPLASYYADPALYAQGQVRVAELVSPDIIFAP-----FA 68  Geobacter metal...
WP_011735339   2 TGmqrFQAIMAG-QLPDRVPVLC------NLLDQGAREL-GMSIKEYYRRGENVAEGQLHMRKKYGYDSLLGL-----FY 68  Pelobacter prop...
Q12XC7         8 TSmerVLTTLGQ-EEPDRVPYFL------FPNMHGAKEL-GMSIKEYFSTSENVVEGQLRLREKYGHDCYTPF-----CY 74  Methanococcoide...
Q2RG09         2 LNyheILATAMFrPINPHVPVVL-----WAIGQTYAPFA-KIPDNEYYADPAKMLEAQVKFYERF-PDVLTIPgiwpdLG 74  Moorella thermo...
Q2RLD3         4 SQwsiIKKCVNM-EELIQVPVGL-----IVDSPWIPGYV-GISTMDYFTIPEKWLEANIKIIKDF-PEIIFLPgfwveYG 75  Moorella thermo...
2EJA_B        76 ILVPLEPLGV-KVEFVEGEG-PKLSWsGK-----VSDLKKYDps--qN--AYVYEIIKRVKE----A-QDEVPVIGFAG- 138 Aquifex aeolicus
Q2NHN4        72 LTAEAEAFGC-EVDLGDMENtPTLRShDIvd--dVEDLEVPDdfvnnGrlPVILESIEILKNe-----YPEVPVIVGMA- 142 Methanosphaera ...
Q2NHV3        74 LAVEAESMGC-EVDLGYGGRtPEVVKsPFe---kPEDIEIPDnfetsGriPVICEAVEILHEr-----YDNLPVCVGIT- 143 Methanosphaera ...
Q8TII4        75 MFIESMALGL-EVKMGRIDIqPSVRSfFNk-----pEEVKYDnfledKyvQTTLDAIKLAKEk-----YPDAAVTAFLV- 142 Methanosarcina ...
Q74AG9        69 LAREAEAFGS-TVVYHRHGP-PNVVKpVVknaadFMRLADPDpd-ahPalLYLRESVRLLAD----GyKGRVPLAGILT- 140 Geobacter sulfu...
Q39S06        69 LALEAEAYGA-ELRYHPDGP-PMVRRhPFraprdAASLSPPAid-tcPglAYLCESVRRLAD----HfCGSVPLAGVLT- 140 Geobacter metal...
WP_011735339  69 VAMEAEMLGCrSIIYAEDGP-PNVGQlIIsepedIRRLQIPDdmeelPrfRELSACIRILKR----EaAGRFPVIGVVT- 142 Pelobacter prop...
Q12XC7        75 ASLEIEAWGG-STIFYEDGP-ANAGApFIkniedIESLEAPSvw-dsPqlLKVLKTTEMLKE----HaGEDVPIIGVVI- 146 Methanococcoide...
Q2RG09        75 LMAELGALGA-ELEFPDDAP-PQSRGgAFedireVENWEVPDpk-kaDytSQTLDYLKYFCKhlpeEpRKKWGFLDGHIf 151 Moorella thermo...
Q2RLD3        76 MATEPSGFGC-KINFYPDRT-PTINHiINsp-eeAEDIFVPNpq-tdGlmPFVLNIYRNIEPkv-kDlGRCIKVVAAR-- 148 Moorella thermo...
2EJA_B       139 --APFTLLSYLIeggaskDFKSTKLFMW------ENPKEYKR-LMDILTETVLAYLKEQIKAGAD--VVQIFD--SWVNN 205 Aquifex aeolicus
Q2NHN4       143 --GPFTLTGHLL------GVEDLVKMLK------TDSFVVED-AVEIALEAQTELVQAFNESGVD--VIAVADptSSPEL 205 Methanosphaera ...
Q2NHV3       144 --GPFTVAGHLI------GVEDILKMIN------LDLFAVED-AIEIAAEAVSAYIKQLNEVKPE--VICVADptSSGDL 206 Methanosphaera ...
Q8TII4       143 --APITLAGDLM------GAENLSMLSIkclqkeKQMQKMKD-WISIALEINKIYAEACVEAGAD--ILYYSDasASPNL 211 Methanosarcina ...
Q74AG9       141 --APVDLPAIIM------GIDAWLETLL------FEPELASA-VLEKTGRHFVAMASRLLGDGAD--FVAMPVmfFNTAL 203 Geobacter sulfu...
Q39S06       141 --APVDLPAMLM------GLDGWLETLL------FEPALAET-VLAAATEHFAAMAGALAAAGAA--CIAIPLmlANPTL 203 Geobacter metal...
WP_011735339 143 --ASFTLPAMLM------GISGWLNLFL------SGPTELRSlLLEKCSQFCRRQILALRQAGAD--LIVYTNsvGTATF 206 Pelobacter prop...
Q12XC7       147 --SPFSAPPMQL------GFSKYFDIMY------ENRELFDK-LMEVNTDFCIEWSNAQIEAGAT--IICYFDpiSSPLL 209 Methanococcoide...
Q2RG09       152 cgGPGEISGLLL------GYDKFSYAMY------DYPQLVHI-LLRKVTDFIKSYIDAQIEIVGEpkRVIIWD--HIPGM 216 Moorella thermo...
Q2RLD3       149 --GPLTIASHLM------GVTNFLIGLK------TDPANTHK-LLKKTTTLAKNWLEAQAEVLSEveGIMVLD--DIVGF 211 Moorella thermo...
2EJA_B       206 LSLEDYGEYVYPYVNYLISELKD-FSdtPVIYFFRGSS-S-FIDLAVD-YRADALSVDWSVDIp---ELFKiyDK----G 274 Aquifex aeolicus
Q2NHN4       206 LDPNDFSEFAQPALEDLSAEMET-----ESILHICGNSrP-ILEEMLD-CGFSGISVEEAVDMteaqQVRA--ETgaetV 276 Methanosphaera ...
Q2NHV3       207 LSPLDFAQLSVPALEDIQEVMKS-----QNVLHICGHTaG-ILKDMLS-CGYNGISIEEAVDMryaqKVKH--ELgdktQ 277 Methanosphaera ...
Q8TII4       212 VMPEFYYQVAVPAEKEIGDFVHHlGC--PWELHICGDTvP-IIEGMAS-TGADCLSVEQAVNMe---EATK--IAgd-vP 281 Methanosarcina ...
Q74AG9       204 VTSRIAAERIVPALAAAFAQVPG-----PLVFHHGGNRiApFLGELAElPGVAGFVIDPRDSFq---DARA--RVgdgrV 273 Geobacter sulfu...
Q39S06       204 VTPEVISRSIVPPLAQAFARTPI-----PIILHHGGNPaMpFLPLVKDlPNVAGFVIGPGDSFa---AARS--IVgeekL 273 Geobacter metal...
WP_011735339 207 VTSRQFHDLVLPSVLRDLEGIGTgD---LVYFNGGGQInP-QLKTLVEqTPLRAFYINPFDDIg---EAAG--MLngqaL 277 Pelobacter prop...
Q12XC7       210 VPKELYKETGYKIEKNVISNLNG-----PTAVHLASGTaLpIIDDIAD-AGAAVVCTSAMEDLa---EVKA--ACkgrmS 278 Methanococcoide...
Q2RG09       217 LSRELFDEFIHPYMKEVFTHVEKaT---LRIYHNENNYpH-LLDLMRD-IPANVCHIGPKHDLv---ESKR--VLk--kC 284 Moorella thermo...
Q2RLD3       212 LSQDDYLEFAHPYLKEIFDAFPQc----IKMYHNDSDNiV-CFSYLQD-LSINIFNFTHLQDIa---KVRQ--LVgnkiC 280 Moorella thermo...
2EJA_B       275 FQGNLEP-AVLY-ASEEVIEEKTLGLLRr-iPVKTRYVFNLGHG---LAPDMELEKVKYLVDLVKSF 335 Aquifex aeolicus
Q2NHN4       277 MVGNVSTsQTLFsKPVEEVKAEVTQALEkgvN-----VLAPSCG---IAPKSPLANLKAFVEARDEF 335 Methanosphaera stadtmanae DS...
Q2NHV3       278 VCGNISTsKTLFrGTPEEVRGEVLEALEkgvD-----VVAPSCG---IAASSPLENIQAMVNARNEF 336 Methanosphaera stadtmanae DS...
Q8TII4       282 VVGNVTPl-LMVeGTEAQIIEETRKGLDggaK-----ASMLGCG---TPPLSSSDKLKTWVKAAADW 339 Methanosarcina acetivorans
Q74AG9       274 LLGKLNGp-LLGlLTPDDACRVTAEILAdrrDDRHFIFASSAAD---VPWNTPPETISAVADTIRQW 336 Geobacter sulfurreducens
Q39S06       274 ILGNLNGp-VLNrLTPEQAGARAAAILAdrrDDPHFVLASSSAD---VPLDTPLETLLAVRAAVEGH 336 Geobacter metallireducens GS-15
WP_011735339 278 LVGTINDi-RLInGSKEEIDDQVKGIMEqgkR-----VTGFAFGtlmMPYVIPEENIRAMLESAYRY 338 Pelobacter propionicus
Q12XC7       279 VLGNLNGi-EMRnWTAETAENKVKEAIDkaaKGGGFILSDNHGE---IPYQVPDEVLIAISNAVRKY 341 Methanococcoides burtonii DS...
Q2RG09       285 VMGNVHPiQELLlGTNEEIEAKCKTIIEt-aGRGGGLWLSTGGG---MAPETPVEKMQVLIDCTKKY 347 Moorella thermoacetica ATCC ...
Q2RLD3       281 LLGNIPPlDVLTnGTPDMVAEAAVNCLNq-hGNKAGIILSAGGG---TSPGTPGRNIHALIKATANY 343 Moorella thermoacetica ATCC ...
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