2WE6


Conserved Protein Domain Family
Peptidase_C12

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pfam01088: Peptidase_C12 
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Ubiquitin carboxyl-terminal hydrolase, family 1
Statistics
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PSSM-Id: 460057
Aligned: 349 rows
Threshold Bit Score: 136.497
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2WE6_A                  8 TPLESNP-DSLYLYSCKLGQSKlkFVDIYGF-NNDL--LDMIpqpVQAVIFLYP-Vndniv------senntNDKHNLKE 76  malari...
XP_014567075            6 SLTESDP-SVFSAILWELGVKGveVEELYGLdAA-L--LEDLq--pQAFIFLFKyLgger---------apaRAGR--QD 68 
WGS:AAWC:PGTG_10272.3   6 CLTESDP-AIFTILLSELGVSGlqVEELWSLdNQ-S--LEQLk-pVHALIFLFKyVnsdqr-------dpskQAGE--QQ 71 
Q4QAT9                  9 CLIESDP-AVFREIIQTVGVKGvsVEDLIMLdSS-M--LEQYe-hVYALVLLFKwQsse----------qasPLGTVVKD 73  Leishm...
Q4D1R0                  5 CLIESDP-AVFTELIERFGARGvaVEEILGLePE-F--LRQYt-nVYGLILLFKwKsgk----------tptSDGVVVPD 69  Trypan...
CCA72744               23 GVVESDP-YVFTSMIQRLGALDlqTEELMSLdALETttSPP-----LGLILCFTwTed----------------syNWED 80 
EKM77238               21 AVIESDP-GVFSSLTRGLGVERveVVELYDIePWAVdhLDP-----YGLIFCFTwHkd-------------aHRPADFED 81 
EPT02264               13 AVIESDP-GVFTTLLQKFGVKGleVTEIYDIePWATdhLKP-----HGLIFCYMcNds------------dsMNASELED 74 
EPB88482               13 NLLEPDPvGTFTKLCTQIGAQSvqVEQIKLLdREAIrnLRp----IHGLIIIIKhKlesfiskddsttnannH------- 81 
XP_007400443           13 AVLESDP-GSFTILLRKLGLQHleVTEIYSIePWATahLEHE---IRALIFCYPcPadsqrd----ssasavNFEEELAD 84 
2WE6_A                 77 NFd-NV------WFIKQYIPNSCGTIALLHLYGNlrnkfeL-DKDSVLDDFFNKVNEMSAEKRGQELKNNKSIENLHHEF 148 malari...
XP_014567075           69 TNfr-------gYFAHQVIENACGTLAILNATMNl----nLtQLGPELSNLKDFSSQLDPQTKGEVLTNSEVLRQVHNSF 137
WGS:AAWC:PGTG_10272.3  72 PAppgT------WFAHQVITNACATLAILNAVMNipstssKiQLGQELSQLKEFSVDLDSQMTGELLTNSERIRAVHNSF 145
Q4QAT9                 74 AP---V------FFAKQVIHNACATLAIMNTLCNyp---dQvELGPKVQRYLSFCQELDPEMRGSLLDSFDELREAHNSF 141 Leishm...
Q4D1R0                 70 AP---V------YFARQTVNNACATLAMVNTLLNys---eSiQLGDELSNLLEFTREMNAYLRGTQVAESDVLREAHNSF 137 Trypan...
CCA72744               81 YDneDLdpsalpWFATQLSHNSCATLAILNVLLNcd-----tDLGPMLSQLKEFSGDMEPVMRGLCITSSKELRDIHNSF 155
EKM77238               82 PTaeRV------WFANQLSDDACATHAILNVLFNc----pDiQLGMELETFRNETQEFSPVMRGLAITNSPLLRRVHNSL 151
EPT02264               75 EDaeRV------WFANQLSDDACASHALLNVLLNc----pHaELGEELRELQAVTAEMSPVMRGLAVSSSQFIRDAHNSL 144
EPB88482               82 -----I------YFSNQVVHDAYAMHALLNVLLNnsd---tvDIGRELDHFKQFTNDFTSMLKGLTLTNSHVLRQAHNSL 147
XP_007400443           85 PDaeDV------WFAYQLSVDACASQTILNVCLNm----eDvSFSAQLRDFHNNTLKMDPLMRGLSFTDCSFIRDAHNSM 154
2WE6_A                149 C----------------------------------------GQVENRDD------ILDv-DTHFIVFVQIEGKIIELDGR 181 malari...
XP_014567075          138 Arsdpfqld-------------------------earpateD--------------DD--VYHFIVYLPIDGHLYELDGL 176
WGS:AAWC:PGTG_10272.3 146 Arpdpfqr--------------------------depkqmsT--------------ED--AYHFITYLPLQGKLYELDGL 183
Q4QAT9                142 Apqsaftk-----------------------------------------dgpspkdAD--VYHFVSFVYRHGHIWELDGL 178 Leishm...
Q4D1R0                138 Apteffvl-----------------------------------------hdetpdaSD--VYHFVSFVYKNGAVWELDGL 174 Trypan...
CCA72744              156 Srpadiraslvktv--------------eevldhhksqsitKRKGKKKKeryvveSPD--AYHFLSYVPHGTRVWEMDGL 219
EKM77238              152 Arsadirtslnsiatdtl-------nskkkdsqpsgrksrtAKSSRATKveegpeTEDapTYHFIGYVPALGKVWELDGL 224
EPT02264              145 Arpadlrgalqaiahstlea--dkarakaakgppakkrkttGSPSKAKKadsddqTQE--QYHFIGYVPAHGKVWELDGL 220
EPB88482              148 Sgr------------------------------------tsKSEESNNE-----------IYHSISYIQSDGYVWELDGL 180
XP_007400443          155 ArpvdiraaehalarttleyaktlkarpegypakrrklgtpKKSQTKQSasdsqeRED--TFHYIGYVPTHGHVWELDGL 232
2WE6_A                182 KD-HPTVHCFT--NG--DNFlYDT-GKIIQDKFI 209 malaria parasite P. falciparum
XP_014567075          177 Qp-WPLDHGAVdaSR----W-TDKaKEVIQARIA 204
WGS:AAWC:PGTG_10272.3 184 Ng-LPVFHGKIpeGQ---SW-TSLaREVIQNRIN 212
Q4QAT9                179 Qe-GPLQCREAt----dANY-REAlVEVVQRRID 206 Leishmania major
Q4D1R0                175 Qk-GPILAADAt----dGNY-KEKlVEVVQKRVi 202 Trypanosoma cruzi
CCA72744              220 Kr-APLECAEL--DNpgDLW-TLAvLPALRSRIE 249
EKM77238              225 Ks-GPLEVGELasDTnrNDW-MDVvRPALRIKMA 256
EPT02264              221 Qr-SAIEVGELdtQAgpGDW-MNVvRPALRMKMH 252
EPB88482              181 Kr-GPLKLGACn----dNNW-LDVaHLEIAKRCE 208
XP_007400443          233 RTnGPLDVGELpqASgrQGW-MDIvRPALQRKMH 265
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