2IBG


Conserved Protein Domain Family
HH_signal
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pfam01085: HH_signal 
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Hedgehog amino-terminal signalling domain
For the carboxyl Hint module, see pfam01079. Hedgehog is a family of secreted signal molecules required for embryonic cell differentiation.
Links
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Statistics
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PSSM-Id: 426037
Aligned: 15 rows
Threshold Bit Score: 235.725
Created: 26-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2IBG_G          1 LYPLVLKQTIPNLSEYTNSASGPLEGVIRRDSPKFK-DLVPNYNRDILFRDEEGTGADRLM-SKRCKEKLNVLAYSVMNE 78   fruit fly
1_pfamImport   17 LVPFLKGEYVPKMSEQTIGASGPSTGRITRTSPRFHhELVPNWNTDIEFRDEEESNEDRFYdAGTCKERLDNLAIRVANQ 96  
XP_025016100   39 TTPLVLEQHIPNVSENTLSASGPSEGKINETDSRFT-KLVPNYNPDIVFKDEEGTGIDRIM-TTRLKEKLDILASLVQNH 116  two-spotted s...
2_pfamImport   16 LRPLLRQQYVPHLSEGTVGASGPSEGRIYRNTPKYR-KLERNYNPDILFREDEEDGSARIM-TKRCKDKVDLLSTLVRNR 93  
NP_001027634  146 LVPFLKGEYVPKMSEQTIGASGPVTGRIRADTPRFRqELVPNWNTDIEFRDEEESNEDRFM-TPICRARLDYLAILVANQ 224  vase tunicate
XP_001605475   39 LTPLVFKQHVPNVSENTLPASGLGEGRVSRNDKRFR-DLVPNYNVDIIFKDEEGTGADRLM-TQRCKEKLNTLAISVMNQ 116  jewel wasp
EGW06030       39 LTPLAYKQFIPNVAEKTLGASGRYEGKITRNSERFK-ELTPNYNPDIIFKDEENTGADRLM-TQRCKDKLNALAISVMNQ 116  Chinese hamster
BAD91000       37 RTPLQYKQRVPNISEDTFGASGPPEGRINRNDERFN-TLSPNNNDDIVFKDEEGTGADRLM-TQRCKDKLNTLAISVMNE 114  Hemicentrotus...
ESN91655      226 MTPFVLKQHVPNLSETTLGASGQPEGKVSRGDPEFK-KLVTNKNPNIIFQNSEGTGADRVM-SKRCSDKLNNLASLTMEQ 303  Helobdella ro...
XP_001943707   53 MKPLVFQQHEPNVSEYSITASGPPEGRIQRNDSRFM-ELVPNYNADIEFKDDEGTGADRLM-TQRCKEKLNTLAISVMNL 130  pea aphid

2IBG_G         79 WPGIRLLVTESWDEDYHHGQESLHYEGRAVTIATSDRDQSKYGMLARLAVEAGFDWVSYVSRRhIYCS 146  fruit fly
1_pfamImport   97 WVRVKLKVLEAWDEGNDRLDDPLHYEGRAVDITTNDQDRRKYPMLARLAVEAGFDWVYYNDNI-VHCS 163 
XP_025016100  117 WPGIKLRVIEAWDDGSQFNPDSLHYEGRAADITTSDKDNSKYGVLARLAVIAGFDWVLYESRYhVHVS 184  two-spotted spider mite
2_pfamImport   94 WAGVSLQVISAWDGDGLHPRGSLHYEGRAVDIKTSDDDTTKYGLLARLAVEAGFDWVFYESKFhVHAS 161 
NP_001027634  225 WARVKLKVLEAWDDGNDKANDPLHYEGRAVDITTDDADRNKYPILARLAVVAGFDWVKYDGKV-VHCS 291  vase tunicate
XP_001605475  117 WPGVKLRVTEGWDEEGKHATDSLHYEGRAVDVTTSDRDRAKYGMLARLAVEAGFDWVYYESRShIHCS 184  jewel wasp
EGW06030      117 WPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAhIHCS 184  Chinese hamster
BAD91000      115 WPGIKLRVVEAWDED-QPNVEPLHAEGRAVDITTSDRDKNKYGALARLAVEAGFDWVNFESKAwVHCS 181  Hemicentrotus pulcherrimus
ESN91655      304 WPGVRLRVVEAWDEDETHPEDSLHYEGRAVDVTTSDKDKSKYGMLARLAVEAGFDWVHYEYRShIHCS 371  Helobdella robusta
XP_001943707  131 WPNVRLRVIDGWVD---RAGSSLHNEGRAVDITTSDRDKSKYGMLARLAVEAGFDWVNY-NRRyIHCS 194  pea aphid
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