3EVS,2HLQ,2L5S


Conserved Protein Domain Family
Activin_recp
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pfam01064: Activin_recp 
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Activin types I and II receptor domain
This Pfam entry consists of both TGF-beta receptor types. This is an alignment of the hydrophilic cysteine-rich ligand-binding domains, Both receptor types, (type I and II) posses a 9 amino acid cysteine box, with the the consensus CCX{4-5}CN. The type I receptors also possess 7 extracellular residues preceding the cysteine box.
Links
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Statistics
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PSSM-Id: 426025
Aligned: 19 rows
Threshold Bit Score: 42.1416
Created: 16-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3EVS_C              23 LRCK-------CHHH------------------------CPEDSVNNICS-------------------------TD--G 44   house mouse
AAB22240            49 RECIyynanweLEKT--------------------------NQSGVESCEg-----------------------eKDkrL 79   African ...
Q24468              34 IECEhfd-ekmCNTT------------------------QQCETRIEHCKm-----------------------eADkfP 65   fruit fly
O35607              32 RLCAfkdpyqqd--------------------lgigesrISHENGTILCSk---------------------------gS 64   house mouse
O16623              77 VSCI-------CNSDkcnddsftipsdvvltippvikcfSQDLIEDNYCFghycty--------------eqeyiRNdfG 135  Caenorha...
Q7QJY6              30 YKCYsce-ppdCADT---------------------------AIHAHYCQn---------------------------aI 54   Anophele...
EKC41469             7 LKCY-------C-EE------------------------CTDR--NQTCE-------------------------TT--G 25   Pacific ...
FlyBase:CG8224-PA  127 IKCH-------CDT-------------------------CKES--NNICE-------------------------TD--G 145  fruit fly
Q8K1T6              28 LRCYtcsfakpCDPV------------------------PRECREDEVCGvsvgtsgrtlvrwpfsrwllsflpmAAaaT 83   house mouse
2HLQ_A              12 dlgI-------GESR------------------------ISHENGTILCSk---------------------------gS 33   sheep

3EVS_C              45 YCFTMIE--EDDSGMPVVTSGCLgl------egSDFQCRDtp---iPH---------QR---RS-IECCtERNECNKDL 99   house mouse
AAB22240            80 HCYASWR--NNSGFIELVKKGCWl---------DDFNCYDrqe-ciAK---------EEn-pQV-FFCCcEGNYCNKKF 135  African c...
Q24468              66 SCYVLWSvnETTGILRIKMKGCFt---------DMHECNQtecvtsAE---------PRq-gNI-HFCCcKGSRCNSNQ 124  fruit fly
O35607              65 TCYGLWE--KSKGDINLVKQGCWshigd-pqecHYEECVVtt---tPP---------SIq-nGTyRFCCcSTDLCNVNF 127  house mouse
O16623             136 DAYTSIN---------SPSRGCSdleya-edlnSPNMCRLl--------------------nGL-LECQcSTPYCNRDQ 183  Caenorhab...
Q7QJY6              55 QCWKSRT--RDPEGNENVQRGCTteh-----eqLPLYCSQnqkpntGDsggpkkrhvSSt-gMYnIECC-TGDYCNNGS 124  Anopheles...
EKC41469            26 LCLTLRA--YRKDGTIKIRYRCIekvdlgpldgDVFECLTs-----nP---------MAs-iSS-KLCCnDEDFCNKHL 86   Pacific o...
FlyBase:CG8224-PA  146 FCFTSVE--KNSDGSIIFSYSCMvvkyn-mqrsKPFECLTs-----nE---------RFd-tYR-IDCC-KSDFCNKNE 204  fruit fly
Q8K1T6              84 SAFLFCPt-EQKEEEVIERKGCL----------PRAQCPLlghatyWS---------RSy-sLR-HQCC-EQDLCNAAA 139  house mouse
2HLQ_A              34 TCYGLWE--KSKGDINLVKQGCWshigd-pqecHYEECVVtt---tPP---------SIqngTY-RFCCcSTDLCNVNF 96   sheep
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