1YBF,5B7Q,3BSF,4QEZ


Conserved Protein Domain Family
PNP_UDP_1

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pfam01048: PNP_UDP_1 
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Phosphorylase superfamily
Members of this family include: purine nucleoside phosphorylase (PNP) Uridine phosphorylase (UdRPase) 5'-methylthioadenosine phosphorylase (MTA phosphorylase)
Statistics
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PSSM-Id: 426013
Aligned: 107 rows
Threshold Bit Score: 84.7032
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1YBF_B         27 PYILLTNFSHYLHVFAEH----------YGVPi--VGEHTSXPNAs-----AEGVTLINFGXGSANAAtiXDLLWAIH-- 87  Bacteroides th...
Q6AVB5         53 YLGVVVPNGFEMEPLLRSpafspakklpYLDV---AGRRFRFGSIg-----EKKVIIVMTGLGMLNSG--VTTQLLLTlf 122 Japanese rice
jgi:Dole_1278   5 RILILTATPVEAAPLVDRi--------sGANA----AGNRVTGMLg-----GTPVRVLVPGPGPVNTA--MALTAVMEkt 65 
Q39Q81          3 SIIIAAATSLELSLLVRSiga-----reVRRKk--GFSDTYRGKVg-----GTTVLLAVTGIGKANTA--SALTALLEry 68  Geobacter meta...
Q6F7X8         48 RLAIIAAFGQEADLLIEStkd----kkeYIIN----GRKFVTGTLe-----GAEVVITLSGISMTNAA--MTTQMITDhf 112 Acinetobacter ...
jgi:Veis_4426  49 RIAVISAFAPELALLLAQlq------qpVSHRi--GGVEFSTGLLa-----GKPVVLFLSGISMTNAA--MNTQRVLDrf 113
Q94K59         47 YIGLVTVIATEENAFLRSvdfrpdpthpFLDL---SGRRFRIGKIh-----GKKVVYVRCGRGMVNGA--AATQQMIDvf 116 thale cress
Q836S7          2 KLGVIAAMDLELQKLLEYf--------pPQRKiqlAKNTFYIYEQk-----TSQVIMVCAGQGKTNAT--LYSQILIDsf 66  Enterococcus f...
P96122          2 TVGVFAALGEEVARVREClgg-----vgTERA----GLTFYVVSVg-----ALQVVYVCGGVGKVNAA--LCTQLLISef 65  Treponema pall...
BAF39056        3 AIAIIGAMDEEVANIATAlsn-----vtVTEE---AGVKVTRGTLetnkgtAVNVAATVGGMGTVNIA--ATTQHLIDad 72 
1YBF_B         88 -PKAVIFLGKCGGLk-LENALGDYLLPIA-----AIR---------GEGTSN---------------------------- 123 Bacteroides th...
Q6AVB5        123 dVEGIVHFGIAGNAd-PDLHIGDVTVPRYwahtgLWNw--------QRYGDGpekelalesngdytrkygalnfsdygva 193 Japanese rice
jgi:Dole_1278  66 lPALVLQTGCGGGFaqAGINKGDVVVATE-----MIDv--------QSGVEPatppdivda------------------- 113
Q39Q81         69 tPRLLIDTGCAGAYggGGLAVGDLAVAST-----EVYg-------dEGILTPsg-------------------------- 110 Geobacter meta...
Q6F7X8        113 nLKGIVFSGIAGSLn-PDLHVGDVVIAKS-----WLApnevyynntKDLPSAcgkpgdisclgikladnvpawknqflre 186 Acinetobacter ...
jgi:Veis_4426 114 dISHIMFSGIAGGVn-PGLHIGDVSVPAQ------WGqym---ewlMAREGPpgqysvpewmksellplp---------- 173
Q94K59        117 nVKGIVHFGIAGNMn-NSMSIGDVSIPKQ-----ITNag------lWDWLNPdkvkgvediayldvgnynvpkgd----- 179 thale cress
Q836S7         67 qIEQLINIGICGCLn-EKLQLFEMVLGEE-----YCH---------YDIRERqs-------------------------- 105 Enterococcus f...
P96122         66 gARVLINTGIAGALd-ERLCVFDVLVSVD-----AVQ---------HDVDVTafgyqkgriprmd--------------- 115 Treponema pall...
BAF39056       73 qPDAVIFSGIAGNLn-TNLHINDVVLGGTl---rYLD---------TDMRLVgqf------------------------- 114
1YBF_B        124 -------------------------DYLPEEVPSLPSFSVLRAISSa---------IQNKG------------------- 150 Bacteroides th...
Q6AVB5        194 gggggnllngvwyqpeevfpadgtpESRRHEFWVPVDGRYYQLAQK----------LEAMPlercvnrtgtatspatcla 263 Japanese rice
jgi:Dole_1278 114 -----------------lpfpvlktPAGEITNRYPADIRLADTACR----------AARNAp------------------ 148
Q39Q81        111 ------------------------wESLEIIGIPQLERGGRRFFNEfplallpaerAVQLGaa----------------- 149 Geobacter meta...
Q6F7X8        187 tnvmnssnyksvaltskfgdtdvpmAYGEMRVDFPVDSKMLNMIDKvqkptetklePICSGanc---------------- 250 Acinetobacter ...
jgi:Veis_4426 174 --------afgmmhprsvqvrsaasPQISQQFWFAADARMLALARS----------LQDIDlahch-------------- 221
Q94K59        180 ---gdnelgsigynyeqlysvtghiNAPQNVFWINTTQEWLHLAADlekmelsqcvNASLClp----------------- 239 thale cress
Q836S7        106 ------------------------iNKFPYQLYYKGDKGMLAELQHl--------------------------------- 128 Enterococcus f...
P96122        116 -------------svewtantalryLVREAFDLCTRDPEWTEGACA----------LSGSGdpp---------------- 156 Treponema pall...
BAF39056      115 ----------------------kpgTADRPIEEYHSDDRLLELADQa---------LNDLN------------------- 144
1YBF_B        151 -----KDYWTgtvYTTNRRVWEY--DEKFKd--YLRSTHASGV-DXETATLXTVGFANKIPXGALLLISDrpxfPEGVKT 220 Bacteroides th...
Q6AVB5        264 rapavARVER---GCSASVFVDN--AAYRQf--LRSRLGVTPI-DMESAAVALVAAQQGAPFIAIRSLSDla-gGGSAES 334 Japanese rice
jgi:Dole_1278 149 -----MATGCgaaMGPIGSVVTIt-ATDLRaqaLFDRFG-LCMeAMEGAAAAHVCLHYGVPFLEIRGASNiag------- 214
Q39Q81        150 ---lgVPVRRgrfVTVSTCSGTT--ARGNA---LARRFNAICE-NMEGAVAAHLALRYGIDCLELRGISNmve------- 213 Geobacter meta...
Q6F7X8        251 ---yhPKIVIgqrGISSGAFLAN---AEYReylHKNLLG-DCV-DMETAAVAQVAYSNNIPFIAFRSLSDlagaDHDPN- 321 Acinetobacter ...
jgi:Veis_4426 222 -agqcLQRRPrvvVGGNGVSGPAfvDNKAFreyTFNTFEAQVL-DMETAATAMVAHGNGVPFIAFRSLSDlaggGAGD-- 297
Q94K59        240 ---kkPKLVVglkAATAYIFVDN--AAYRNf--LYDTFGVSSS-DMESSAVAMTCASNGYPIIVIRGLSDlageGGD--- 308 thale cress
Q836S7        129 ----dEKIKCvrfGTGEGFVCDT--TEKRN---LIEQFSIDCV-DMESAAIAQCCFLNDCAFVSIRIICD----RADANA 194 Enterococcus f...
P96122        157 --srvSRLVEgrvASGDLFVSDA--QTRAR---IIREFGAHGV-EMEGAAFAHVASVNGVPFVIIRCISD----GAGAEQ 224 Treponema pall...
BAF39056      145 -----IHHIVgiiATGNYFVDDP--QKVEQ---VIRETGADAV-EMEGAAVAHVAARNDVPALVIRALSD----NADTDY 209
1YBF_B        221 e--ESDQLVTDNFAEEHLXLGIDALE 244 Bacteroides thetaiotaomicron VPI-5482
Q6AVB5        335 ---NEAGVFAALAAQNAVAVAVKFIS 357 Japanese rice
jgi:Dole_1278 215 -rrDRADWDIPLAATNAAISVCAFIA 239
Q39Q81        214 -drDLSGWNIPLAVERAQRFILKFLE 238 Geobacter metallireducens GS-15
Q6F7X8        322 ---VAAFFGSGIAQRNAAKLTMAFID 344 Acinetobacter baylyi
jgi:Veis_4426 298 ---NEMATFMQLAAANSAKVLLAFLA 320
Q94K59        309 ---NTVHKFGSLAATNTAKAVLEFIR 331 thale cress
Q836S7        195 v--KVTEDTQTQAMEKVFELVCAYIN 218 Enterococcus faecalis
P96122        225 dvsMSYKEFSTRAARRSALLTLRVLE 250 Treponema pallidum subsp. pallidum str. Nichols
BAF39056      210 e--DFKTFDISEYADTAAKLTVNIAK 233
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