8I1B,1ILR,3WO3


Conserved Protein Domain Family
IL1

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pfam00340: IL1 
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Interleukin-1 / 18
This family includes interleukin-1 and interleukin-18.
Statistics
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PSSM-Id: 395269
Aligned: 13 rows
Threshold Bit Score: 122.943
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
8I1B_A    31 LNGQNINQQVIFSMSFVQGEPSNDKIPVA--LGLKGKNL-YLSCVMKdGTPTLQLESVD-PKQYPKKKMEKRFVFNKIEV 106 house mouse
P41687   146 LNGQNMNQQVVFRMSFVHGEENSKKIPVV--LCIKKNNL-YLSCVMKdGKPTLQLEMLD-PKVYPKKKMEKRFVFNKTEI 221 domestic cat
P26889   145 LLTGDLKREVVFCMSFVQGDDSNNKIPVT--LGIKGKNL-YLSCVMKdNTPTLQLEDID-PKRYPKRDMEKRFVFYKTEI 220 pig
P09428   144 LLSQEMNREVVFCMSFVQGEERDNKIPVA--LGIKDKNL-YLSCVKKgDTPTLQLEEVD-PKVYPKRNMEKRFVFYKTEI 219 cattle
P25085    61 LQGPNIKLEEKIDMVPID--------LHSvfLGIHGGKL-CLSCAKSgDDIKLQLEEVNiTDLSKNKEEDKRFTFIRSEK 131 house mouse
1ILR_2    35 LQGPNVNLEEKIDVVPIE--------PHAlfLGIHGGKM-CLSCVKSgDETRLQLEAVNiTDLSENRKQDKRFAFIRSDS 105 human
P26890    60 LQGPNAKLEERIDVVPLE--------PQLlfLGIQRGKL-CLSCVKSgDKMKLHLEAVNiTDLGKNKEQDKRFTFIRSNS 130 rabbit
3WO3_C    36 sDCRDNAPRTIFIISMYK-DSQPRGMAVT--ISVKCEKIsTLSCENK----IISFKEMNpPDNIKDTKSDIIF-FQRSVP 107 human
AAT99559  38 sDCSDNAPQTIFIIYMYK-DSLTRGLAVT--ISVQCKKMsTLSCENK----IISFKEMNpPDNIDNEGSDIIF-FQRSVP 109
P08831   156 TTLNNLEEAVKFDMVAYVSE-EDSQLPVT--LRISKTQL-FVSAQNE-DEPVLLKEMPEtPKIIKD-ETNLLFFWEKHGS 229 cattle
P04822   156 APLQNLGDAVKFDMGVYMTS-EDSILPVT--LRISQTPL-FVSAQNE-DEPVLLKEMPEtPRIITDSESDILFFWETQGN 230 rabbit
P01582   158 TWLNDLQQEVKFDMYAYSSGGDDSKYPVT--LKISDSQL-FVSAQGE-DQPVLLKELPEtPKLITGSETDLIFFWKSINS 233 house mouse
EHH55841 155 aAIHNLDEAVKFDMGAYTSSKDDTKVPVI--LRISKTQL-YVSAQDE-DQPVLLKEMPEiPKTITGSETNFLFFWETHGT 230
8I1B_A   107 KSKVE--FESAEFPNWYISTSQAEHKPVFLGNN-SGQD-IIDFTM 147 house mouse
P41687   222 KGNVE--FESSQFPNWYISTSQAEEMPVFLGNTkGGQD-ITDFIM 263 domestic cat
P26889   221 KNRVE--FESALYPNWYISTSQAEQKPVFLGNSkGRQD-ITDFTM 262 pig
P09428   220 KNTVE--FESVLYPNWYISTSQIEERPVFLGHFrGGQD-ITDFRM 261 cattle
P25085   132 GPTTS--FESAACPGWFLCTTLEADRPVSLTNTpEEPLiVTKFYF 174 house mouse
1ILR_2   106 GPTTS--FESAACPGWFLCTAMEADQPVSLTNMpDEGVmVTKFYF 148 human
P26890   131 GPTTT--FESASCPGWFLCTALEADQPVSLTNTpDDSIvVTKFYF 173 rabbit
3WO3_C   108 GHDNKmqFESSSYEGYFLACEKERDLFKLILK---KEDeLGDRSi 149 human
AAT99559 110 GHDDKiqFESSLYKGYFLACKKENDLFKLILK---RQDdNRDKSV 151
P08831   230 MDY----FKSVAHPKLFIATKQEK-----LVHMaSGPPsITDFQI 265 cattle
P04822   231 KNY----FKSAANPQLFIATKPEH-----LVHMaRGLPsMTDFQI 266 rabbit
P01582   234 KNY----FTSAAYPELFIATKEQS-----RVHLaRGLPsMTDFQI 269 house mouse
EHH55841 231 KNY----FISVAHPNLFIATKHDN-----WVCLaKGLPsITDFQI 266
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