2WZ1,1AB8,3UVJ,6R3Q


Conserved Protein Domain Family
Guanylate_cyc

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pfam00211: Guanylate_cyc 
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Adenylate and Guanylate cyclase catalytic domain
Statistics
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PSSM-Id: 425528
Aligned: 23 rows
Threshold Bit Score: 182.442
Created: 16-Apr-2021
Updated: 29-Sep-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2WZ1_A              5 VPAKRYDNVTILFSGIVGFNAFCSKHAsgegAMKIVNLLNDLYTRFDTLTDSRKnpfVYKVETVGDKYMTVSGLP----- 79   human
mpitm:STAUR_3482  220 etSPELREVTLLFADIRDFTSLSERLR----PEQVVTLLNEYYGRMVEVVFRHG---GTLDKFIGDALMVYFGAP----- 287  Stigmatel...
P14605           1323 EVSPPKGCIAMVFTDIKNSTLLWERH-----PIAMRSAIKTHNTIMRRQLRATG---GYEVKTEGDAFMVCFQTV----- 1389 Schizosac...
P51830            385 FKMQQIEEVSILFADIVGFTKMSANKS----AHALVGLLNDLFGRFDRLCEQTK---CEKISTLGDCYYCVAGCP----- 452  house mouse
P19754            296 IYIQRHDNVSILFADIVGFTGLASQCT----AQELVKLLNELFGKFDELATENH---CRRIKILGDCYYCVSGLT----- 363  cattle
P21932            310 MYMYRHENVSILFADIVGFTQLSSACS----AQELVKLLNELFARFDKLAAKYH---QLRIKILGDCYYCICGLP----- 377  Norway rat
P19754            862 LYYQSYSQVGVMFASIPNFNDFYIELDgnnmGVECLRLLNEIIADFDELMDKDFykdLEKIKTIGSTYMAAVGLAptag- 940  cattle
P40145            973 LYSQSYDAVGVMFASIPGFADFYSQTEmnnqGVECLRLLNEIIADFDELLGEDRfqdIEKIKTIGSTYMAVSGLSpek-- 1050 human
P21932            914 LYSQSYDEIGVMFASLPNFADFYTEESinngGIECLRFLNEIISDFDSLLDNPKfrvITKIKTIGSTYMAASGVTpdvnt 993  Norway rat
6R3Q_A            385 FKMQQIEEVSILFADIVGFTKMSANKS----AHALVGLLNDLFGRFDRLCEETK---CEKISTLGDCYYCVAGCP----- 452  
2WZ1_A             80 -------------EPCIHHARSICHLALDMMEIA-GQVQVDG---------------ESVQITIGIHTGEVVTGVIG--Q 128  human
mpitm:STAUR_3482  288 -------------IADPAHARRGVQCALDMVQEL-ETVNALRsar----------gePCLRIGVGVHTGPAVLGNIGsaT 343  Stigmatel...
P14605           1390 ----------------PAALLWCFSVQLQLLSADwPNEIVESvqgrlvlgsknevlyRGLSVRIGVNYGVTVSELD---P 1450 Schizosac...
P51830            453 -------------EPRADHAYCCIEMGLGMIKAI-EQFCQEKk--------------EMVNMRVGVHTGTVLCGILG--M 502  house mouse
P19754            364 -------------QPKTDHAHCCVEMGLDMIDTI-TSVAEATe--------------VDLNMRVGLHTGRVLCGVLG--L 413  cattle
P21932            378 -------------DYREDHAVCSILMGLAMVEAI-SYVREKTk--------------TGVDMRVGVHTGTVLGGVLG--Q 427  Norway rat
P19754            941 ---------tkakKCISSHLSTLADFAIEMFDVL-DEINYQSy--------------NDFVLRVGINVGPVVAGVIG--A 994  cattle
P40145           1051 ----------qqcEDKWGHLCALADFSLALTESI-QEINKHSf--------------NNFELRIGISHGSVVAGVIG--A 1103 human
P21932            994 ngftssskeeksdKERWQHLADLADFALAMKDTL-TNINNQSf--------------NNFMLRIGMNKGGVLAGVIG--A 1056 Norway rat
6R3Q_A            453 -------------EPRADHAYCCIEMGLGMIRAI-EQFCQEKk--------------EMVNMRVGVHTGTVLCGILG--M 502  
2WZ1_A            129 RMPRYCLFGNTVNLTSRTETTGEKGKINV--SEYTYRCL-----MspensDPQFHLEHRGPVSMK-G----K-------- 188  human
mpitm:STAUR_3482  344 RRLEYTAIGDTVNLASRIESLTKTRDVPIlaSRATREQA-----G------DTFLWNEMAPASVP-G----K-------- 399  Stigmatel...
P14605           1451 ITRRMDYYGPVVNRTSRVVSVADGGQIAV--SAEVVSVL-----NqldseTMSSEKTNVNEMEVR-A------------- 1509 Schizosac...
P51830            503 RRFKFDVWSNDVNLANLMEQLGVAGKVHI--SEATAKYL-----D--------------DRYEMEdGrvieRlgqsvvad 561  house mouse
P19754            414 RKWQYDVWSNDVTLANVMEAAGLPGKVHI--TKTTLACL-----N--------------GDYEVEpGhgheRnsf----l 468  cattle
P21932            428 KRWQYDVWSTDVTVANKMEAGGIPGRVHI--SQSTMDCL-----K--------------GEFDVEpGdggsRcdy----l 482  Norway rat
P19754            995 RRPQYDIWGNTVNVASRMDSTGVQGRIQV--TEEVHRLL-----R-----RGSYRFVCRGKVSVK-G----K-------- 1049 cattle
P40145           1104 KKPQYDIWGKTVNLASRMDSTGVSGRIQV--PEETYLIL-----K-----DQGFAFDYRGEIYVK-GiseqE-------- 1162 human
P21932           1057 RKPHYDIWGNTVNVASRMESTGVMGNIQV--VEETQVIL-----R-----EYGFRFVRRGPIFVK-G----K-------- 1111 Norway rat
6R3Q_A            503 RRFKFDVWSNDVNLANLMEQLGVAGKVHI--SEATAKYLddryeM-----EDGKVTERLGQSVVA-D----Q-------- 562  
2WZ1_A            189 --KE-PMQVWFLS 198  human
mpitm:STAUR_3482  400 --SQ-PVAIFTpr 409  Stigmatella aurantiaca DW4/3-1
P14605           1510 --LK-QIGYIIHN 1519 Schizosaccharomyces pombe 972h-
P51830            562 qlKG-LKTYLISG 573  house mouse
P19754            469 ktHN-IETFFIVP 480  cattle
P21932            483 deKG-IETYLIIA 494  Norway rat
P19754           1050 --GE-MLTYFLEG 1059 cattle
P40145           1163 --GK-IKTYFLLG 1172 human
P21932           1112 --GE-LLTFFLKG 1121 Norway rat
6R3Q_A            563 --LKgLKTYLIAG 573  
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