7AP4,4DPG,1N9W


Conserved Protein Domain Family
tRNA-synt_2

?
pfam00152: tRNA-synt_2 
Click on image for an interactive view with Cn3D
tRNA synthetases class II (D, K and N)
Statistics
?
PSSM-Id: 425487
Aligned: 88 rows
Threshold Bit Score: 202.796
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
7AP4_B   124 SEELRLKYRYLDL-RRRRMQENLRLRHRVIKAIWDFLDREGFVQVETPFLTKS------TPEGARDFLVPYRHEp----G 192 Thermus thermophilu...
EKC34078  83 SHEHLRQFLHLRP-KTALTSAVLRIRNTATMAVHKYFQENGYIFIHTPILSSNd-----CEGAGQLFTVKVSEKndddeK 156
Q7NBK8    31 yMYEDFRKNFIKTiKNERYSNLLKLFSVINKLTYIWMENNNVEIVNLPITTQSvtspmgLGSDSKPYKVISKSNln---- 106 Mycoplasma gallisep...
Q6C700   128 KQEFLRTLPALRW-RTSVNSSTLRYRSFCMAQMTNFFAENDFVQTNPPLLTSSd-----CEGAGEVFKVAGGGKg----- 196 Yarrowia lipolytica
Q8BGV0   135 PLEYLRQYPHLRC-RTNALGSILRVRSEATAAIHSYFKDNGFVHIHTPVLTSNd-----CEGAGELFQVEPSSKikgpkE 208 house mouse
Q8U4D3   114 sPELLLDYRHLHI-RTPKASAIMKVKETLIMAAREWLLKDGWHEVFPPILVTGa-----VEGGATLFKL----------- 176 Pyrococcus furiosus...
Q8SQK8   124 SVNAILTNGHLGL-RTKKRQLFLKARGHLLKIIRDFYFEGEYTEVTPPTMVQTq-----VEGGSTLFKL----------- 186 Encephalitozoon cun...
1N9W_B   104 nPDTLLEYRYVTL-RGEKARAPLKVQAALVRGFRRYLDRQDFTEIFTPKVVRAg-----AEGGSGLFGV----------- 166 Thermus thermophilus
Q97DB5   160 NIDTLIENRILSM-RNSRVNSVFKIETEIAHGFSEFLVKNGFTEIYTPKIVSEg-----AEGGTELFKL----------- 222 Clostridium acetobu...
Q7SFD2   259 TMLTHLDNIIMHK-RAPVQQAIADIRMEVKDLFRSYLKSHGFKEFEPPCLIGAa-----SEGGANVFRM----------- 321 Neurospora crassa
7AP4_B   193 ----LFY-----ALPQSPQLFKQMLMVAg-LDRYFQIARCFRDEDLRADRQP-DFTQLDLEM--SFVEVED-VLELNERL 258 Thermus thermophilu...
EKC34078 157 klipEFFts-pvFLTVSGQLHLEAVASG--ISKVYTFSPAFRAERSQTSNHLaEFYMIEAEL--SFTECLEdIMQVMEGL 231
Q7NBK8   107 ---yEFY------LADSMQFHLELMLRAkdISSVGYITNTFRGEQVD-NRHLhQFNHFEIEMlgNLNNCKEkIIDYIKFI 176 Mycoplasma gallisep...
Q6C700   197 ---dKFFgdkpaYLTVSTQLHLEVLAAA--VGRVWTFTPAFRAENSDTNRHLsEFWMAEAEI--SFIDDLEpLMDLAEGM 269 Yarrowia lipolytica
Q8BGV0   209 ----SFFdv-paFLTVSGQLHLEVMSGA--FTQVFTFGPTFRAENSQSRRHLaEFYMVEAEI--SFVESLQdLMQVMEEL 279 house mouse
Q8U4D3   177 ----KYFdk-yaYLSQSAQLYLEAAIFG--LEKVWSLTPSFRAEKSRTRRHLtEFWHLELEA--AWMDLWD-IMKVEEEL 246 Pyrococcus furiosus...
Q8SQK8   187 ----DYYge-daYLTQSSQLYLETVVPA--SHRAYCIMPSYRAEKSRTRRHLsEYTHVEAEM--ADIDLDG-LISSIEAL 256 Encephalitozoon cun...
1N9W_B   167 ----DYFek-raYLAQSPQLYKQIMVGV--FERVYEVAPVWRMEEHHTSRHLnEYLSLDVEM--GFIADEEdLMRLEEAL 237 Thermus thermophilus
Q97DB5   223 ----KYFdk-eaYLAQSPQFYKQMMVAAg-YERVFEIGHVYRAESHDTKRHLnEYISMDLEM--GFINDEMdLIRFEIEL 294 Clostridium acetobu...
Q7SFD2   322 ----PYFdk-eaFLAQSPQFYKQFEIAGg-RKRVFSIGPVFRAENSNTPRHMtEFTGLDLEM--EIKKDYReVLLMLEGV 393 Neurospora crassa
7AP4_B   259 MAHVFREA-LGV----------------------------ELPLp-FP-------------RLSYEEAMER--------- 286 Thermus thermophilu...
EKC34078 232 VKSLTREVmETSaddirfvhrrn------sassdlltaidDMINkeFI-------------RLPYVEALNIvnkicespe 292
Q7NBK8   177 VNELIKKHknlidffntnnsnrlkkwlsnevidlkhdhviS-----LL-------------KLEYPVGIEKiylnk---- 234 Mycoplasma gallisep...
Q6C700   270 VKSCLAPLmEEGnkarndlldarr----saeqkeelldrwDMANcdFP-------------RLTYKQAIKIlnlqhlkep 332 Yarrowia lipolytica
Q8BGV0   280 FKATTEMVlSHCpedvelchqf--------iaagqkgrleHMLKnnFL-------------IISYTEAIEIlkqasqnf- 337 house mouse
Q8U4D3   247 VSYMVQRTlELRkkeiemf--------------rddlttlKNTEppFP-------------RISYDEAIDIlqskgi--- 296 Pyrococcus furiosus...
Q8SQK8   257 VSYSMRRFyEEMksdilsv--------------fpefefhKVPRtpFK-------------RIKYSEAIELlkskgykke 309 Encephalitozoon cun...
1N9W_B   238 LAEMLEEAlNTAgdeirl----------------lgatwpSFPQd-IP-------------RLTHAEAKRIlkeel---- 283 Thermus thermophilus
Q97DB5   295 LKYIFQNVrQKCsksiellk-------------veiptiqE-----VP-------------IMPLNEAITIlrevyn--- 340 Clostridium acetobu...
Q7SFD2   394 LLHIFRGIkERCaa------------------------eiELVRsvYPaeefllpepgkevRLTFAEGQKLlreegpee- 448 Neurospora crassa
7AP4_B       --------------------------------------------------------------------------------     Thermus thermophilu...
EKC34078 293 lkvmlteknpyiwdpasdslttpmvsltlrddldqklnvtsltnpvdvyisnfnpviqkseenftlsvqdfdsfnatqtt 372
Q7NBK8       --------------------------------------------------------------------------------     Mycoplasma gallisep...
Q6C700       --------------------------------------------------------------------------------     Yarrowia lipolytica
Q8BGV0       --------------------------------------------------------------------------------     house mouse
Q8U4D3       --------------------------------------------------------------------------------     Pyrococcus furiosus...
Q8SQK8       --------------------------------------------------------------------------------     Encephalitozoon cun...
1N9W_B       --------------------------------------------------------------------------------     Thermus thermophilus
Q97DB5       --------------------------------------------------------------------------------     Clostridium acetobu...
Q7SFD2       --------------------------------------------------------------------------------     Neurospora crassa
7AP4_B       --------------------------------------------------------------------------------     Thermus thermophilu...
EKC34078 373 elcrimtfnstegrstvftvrpltfnltvnvievqnrtnmshlnvraagvslsklnnfthifssfptgevslafcidqtv 452
Q7NBK8       --------------------------------------------------------------------------------     Mycoplasma gallisep...
Q6C700       --------------------------------------------------------------------------------     Yarrowia lipolytica
Q8BGV0       --------------------------------------------------------------------------------     house mouse
Q8U4D3       --------------------------------------------------------------------------------     Pyrococcus furiosus...
Q8SQK8       --------------------------------------------------------------------------------     Encephalitozoon cun...
1N9W_B       --------------------------------------------------------------------------------     Thermus thermophilus
Q97DB5       --------------------------------------------------------------------------------     Clostridium acetobu...
Q7SFD2       --------------------------------------------------------------------------------     Neurospora crassa
7AP4_B       --------------------------------------------------------------------------------     Thermus thermophilu...
EKC34078 453 enylelsrqcltltscgltletqlyfavcmywnvtedkwsssgcqvgqqttpasmhcqcthltafsgsflvapnfvdpfa 532
Q7NBK8       --------------------------------------------------------------------------------     Mycoplasma gallisep...
Q6C700       --------------------------------------------------------------------------------     Yarrowia lipolytica
Q8BGV0       --------------------------------------------------------------------------------     house mouse
Q8U4D3       --------------------------------------------------------------------------------     Pyrococcus furiosus...
Q8SQK8       --------------------------------------------------------------------------------     Encephalitozoon cun...
1N9W_B       --------------------------------------------------------------------------------     Thermus thermophilus
Q97DB5       --------------------------------------------------------------------------------     Clostridium acetobu...
Q7SFD2       --------------------------------------------------------------------------------     Neurospora crassa
7AP4_B       --------------------------------------------------------------------------------     Thermus thermophilu...
EKC34078 533 daalfltffsnpvvvscviliwliyftlltwakkqdrldkvwdvenlinlrtqyrggviiahennpdhkyaylvcvitgw 612
Q7NBK8       --------------------------------------------------------------------------------     Mycoplasma gallisep...
Q6C700       --------------------------------------------------------------------------------     Yarrowia lipolytica
Q8BGV0       --------------------------------------------------------------------------------     house mouse
Q8U4D3       --------------------------------------------------------------------------------     Pyrococcus furiosus...
Q8SQK8       --------------------------------------------------------------------------------     Encephalitozoon cun...
1N9W_B       --------------------------------------------------------------------------------     Thermus thermophilus
Q97DB5       --------------------------------------------------------------------------------     Clostridium acetobu...
Q7SFD2       --------------------------------------------------------------------------------     Neurospora crassa
7AP4_B   287 ------------------------------------------------------------------------------YG 288 Thermus thermophilu...
EKC34078 613 wknagttssvslsfagteghsgrhclsesvpgrqcflsgyedwflvttshslgdlrslsvwhdssgksphwsvscewgDD 692
Q7NBK8   235 --------------------------------------------------------------------------ndfiES 240 Mycoplasma gallisep...
Q6C700   333 ----------------------------------------------------------------------fahrpdyeVG 342 Yarrowia lipolytica
Q8BGV0   338 -----------------------------------------------------------------------aftpkwgVD 346 house mouse
Q8U4D3   297 -------------------------------------------------------------------------nvqwgDD 303 Pyrococcus furiosus...
Q8SQK8   310 ----------------------------------------------------------------------dntdfelgDD 319 Encephalitozoon cun...
1N9W_B   284 -------------------------------------------------------------------------gypvgQD 290 Thermus thermophilus
Q97DB5   341 -------------------------------------------------------------------------kkeltTD 347 Clostridium acetobu...
Q7SFD2   449 -----------------------------------------------------------------------frnvtddED 457 Neurospora crassa
7AP4_B   289 SDKPDLRFGLElkevgplfrqsgfrvfqeaesvkalalpkalsrkevaeleevakrhkaqglawarveeggfsggvakfl 368 Thermus thermophilu...
EKC34078 693 LQRAHEKALVK--------------------------------------------------------------------- 703
Q7NBK8   241 VNSKGEQYLIN--------------------------------------------------------------------- 251 Mycoplasma gallisep...
Q6C700   343 LRSEHEKWLAT--------------------------------------------------------------------- 353 Yarrowia lipolytica
Q8BGV0   347 LQTEHEKYLVR--------------------------------------------------------------------- 357 house mouse
Q8U4D3   304 LGADEERVLTE--------------------------------------------------------------------- 314 Pyrococcus furiosus...
Q8SQK8   320 IPDAAERYLVEv-------------------------------------------------------------------- 331 Encephalitozoon cun...
1N9W_B   291 LSEEAERLLGEya------------------------------------------------------------------- 303 Thermus thermophilus
Q97DB5   348 IDHEGEELIGRfv------------------------------------------------------------------- 360 Clostridium acetobu...
Q7SFD2   458 MSTPQEKALGAiv------------------------------------------------------------------- 470 Neurospora crassa
7AP4_B   369 epvreallqatearpgdtllfvagprkvaatalgavrlraadllglkREGFRFLWVVDFPllewdeeeeawtYMHHPFTS 448 Thermus thermophilu...
EKC34078 704 -----------------------------------------------HCGNVPVFVTDYP------------EELKPFYA 724
Q7NBK8   252 -----------------------------------------------KFKNNIIWLSNFP------------WQLVPFYQ 272 Mycoplasma gallisep...
Q6C700   354 -----------------------------------------------EYFISPVFVTDYP------------KEQKPFYM 374 Yarrowia lipolytica
Q8BGV0   358 -----------------------------------------------HCGNIPVFVINYP------------SELKPFYM 378 house mouse
Q8U4D3   315 ------------------------------------------------EFDRPFFVYGYP------------KQIKAFYM 334 Pyrococcus furiosus...
Q8SQK8   332 -----------------------------------------------VGDGCPVFLTHFL------------VGHKPFYM 352 Encephalitozoon cun...
1N9W_B   304 ---------------------------------------------keRWGSDWLFVTRYP------------RSVRPFYT 326 Thermus thermophilus
Q97DB5   361 ---------------------------------------------keKYNSDFVFLTHYS------------KDKRPMYT 383 Clostridium acetobu...
Q7SFD2   471 ---------------------------------------------rkKFNTDFYVLDKFP------------EGARPFYA 493 Neurospora crassa
7AP4_B   449 PHPEDlpllekdpgRVRALAYDLVLN-GV-EVGGGSIRIHDPRLQARVFRLLGIGeeeqrEKFGFFLEALEY-GAPPHGG 525 Thermus thermophilu...
EKC34078 725 RLNED---------HKTVAGLDLLIP-GVgELCGGTLREERYDILHQKLKSKNLL-----NTLSWYLELREF-GSCPHGG 788
Q7NBK8   273 KIEGDy-----------AINSDLLI--GIgETVGSGQRCITYKETYDSILKHKNNp----KHYDWYLKMKLE-SELETSG 334 Mycoplasma gallisep...
Q6C700   375 KQSPHd--------SQTVACFDLLMP-HIgEVIGGSVREDNYDTLLKNIETTGMDk----SALEWYLELRKQ-GSTPHGG 440 Yarrowia lipolytica
Q8BGV0   379 RENEDg-------pQNTVAAVDLLVP-GVgELFGGSLREERYHVLEQRLARSGLT-----KAYQWYLDLRKF-GSVPHGG 444 house mouse
Q8U4D3   335 KEDPNd--------PRKVLAADMLAPeGYgEIIGGSQREDDYEKLLNRILEEGMDp----KDYEWYLDLRKY-GSVPHSG 401 Pyrococcus furiosus...
Q8SQK8   353 RKDENd--------KGLTESTDLLFP-GIgEILGGSMRQDTYEDLIEGFRRENINi----DPYYWYLDMARF-GPCKHGG 418 Encephalitozoon cun...
1N9W_B   327 YPEEDg----------TTRSFDLLFR-GL-EITSGGQRIHRYEELLESLKAKGMDp----EAFHGYLEVFKY-GMPPHGG 389 Thermus thermophilus
Q97DB5   384 MPCGKn----------LTHSFDLIFR-GM-EITTGGQRINDYDMLRQSMLDKGLKv----ESFKSYLDVFKF-GMPPHGG 446 Clostridium acetobu...
Q7SFD2   494 KLDDAn--------PKVTNAFDFFLR-GQ-EILSGGQRINDPEELEARIIQKGVDpk--sAGIKDYVDVFRQaGVPAHGG 561 Neurospora crassa
7AP4_B   526 IAWGLDRLLALMTGSPSIREVIAFPKNK 553 Thermus thermophilus HB8
EKC34078 789 FGMGFDRYLQFLLGMPSIKDVTAFPRWT 816
Q7NBK8   335 FGLGLERLVLFIIDEKDIRNVQLLPRET 362 Mycoplasma gallisepticum
Q6C700   441 FGMGFERLISYATGIENIRDVTAFPRWV 468 Yarrowia lipolytica
Q8BGV0   445 FGMGFERYLQCILGVDNIKDVIPFPRFT 472 house mouse
Q8U4D3   402 FGLGVERLVAWVLKLDHIRWASLFPRTp 429 Pyrococcus furiosus DSM 3638
Q8SQK8   419 YGLGFERFLMGLMRYESVDEATLYPRKV 446 Encephalitozoon cuniculi GB-M1
1N9W_B   390 FAIGAERLTQKLLGLPNVRYARAFPRDR 417 Thermus thermophilus
Q97DB5   447 LAIGLERITIKLLNLDNIREAAFFVRDK 474 Clostridium acetobutylicum
Q7SFD2   562 GGIGLDRVVAWFLNLPSVHLAAYYPRTP 589 Neurospora crassa
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap