7A5O,7A5O,7A5O


Conserved Protein Domain Family
VWD

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pfam00094: VWD 
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von Willebrand factor type D domain
Swiss:P17554 contains a vwd domain. Its function is unrelated but the similarity is very strong by several methods.
Statistics
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PSSM-Id: 459671
Aligned: 40 rows
Threshold Bit Score: 87.8111
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
7A5O_I   17 CSTWGNFHYKTFDGDVFRFPGLCDYNfaSDCR-GSYKeFAVHLKRGPGQAEAPAG-VESILLTIK----DDTIYLTR--- 87   human
P98167 1010 CRASGAPHYVTFDGLALTFPGACEYL--LVREaSGQ----FMVSAQNLPCGASGLtCTKALTVRLq---GTVVHMLRg-- 1078 cattle
P98092 1621 CNMTGR-TFNTFDGMEYKYDV-C-FHm-LARDnKFD--AWLIIVRKNCRLDGCTN----ELIVMQd---DQLIQVKPn-- 1685 domestic silkworm
P87498 1642 CEVSKG-DFKTFDRMSFTCSFNKSCNvvVAQDcTEHP--KFIITTRKVDHQSLSR----EVHINTs---SANITICPaad 1711 chicken
P02845 1581 CSVSYN-KIKTFNEVKFNYSMPANCYhiLVQDcSSE--LKFLVMMKSAGEATNLK----AINIKIg---SHEIDMHPvn- 1649 chicken
P06125 1308 CKVDQS-EVSTFDNVIYRAPLTT-CYslVAKDcSEQ--PRFAVLAKKINKNSEEL----LVKVVRr---EEEIVVKKsd- 1375 Caenorhabditis elegans
P55155 1312 CKVQKN-QIRTFDDVLYNTPLTT-CYslIAKDcSEE--PTFAVLSKKTEKNSEEM----IIKVIRg---EQEIVAQLqn- 1379 Caenorhabditis elegans
O55225  139 CRTWGQHHVETFDGLYYYFSGKGSYTlvGHHEpEGQS-FSIQVHNDPQCGSAHYT-CPRSVSLFLs--gEREICLAKe-- 212  house mouse
Q28295   35 CSLFGGDFINTFDESMYSFAGDCSYL--LAGDcQEHS-VSLIGG-FQNGK-R------VSLSVYLg--eFFDIHLFVn-- 99   dog
Q28295  388 CLVTGQSHFKSFDNRYFTFSGVCHYL--LAQDcQDHT-FSVVIETVQCADDLDAV-CTRSVTVRLpghhNSLVKLKHg-- 461  dog
7A5O_I   88 --HLAVLNGAVVST----PHYSPGL--LIEKSD--AYT-KVYS-RAGLTLM-WNRED--ALMLELDTKFRNHTCGLCGDY 152  human
P98167 1079 --RAVMVNGVSVTP----PKVYSGP--GLSLHT--AGl-FLLL-STRLGLT-LLWDGgtRVPVQLSPQLRGRVAGLCGDF 1145 cattle
P98092 1686 --MMVTYNNYEYTIeqtkKICFQKNsfDVDRLG--NGIsITSR-KYNFTVL-FNKEG--DVKIGVLKKHMGGVDGLCGAY 1757 domestic silkworm
P87498 1712 ssLLVTCNKESVLSd--sGVSEYEKd-NIKIYK--NGKtVIVE-APIHGLKnVNFDGe-ILKVTVASWMRGKTCGVCGNN 1784 chicken
P02845 1650 gqVKLLVDGAESPTan-iSLISAGA--SLWIHNenQGFaLAAPgHGIDKLY-FDGKT--ITIQVPLWMA-GKTCGICGKY 1722 chicken
P06125 1376 dkFLVKVDGKKVN-----PTELEQY--NIEILG---DNlIVIR-LPQGEVR-FDGYT--VKTNMPSVASQNQLCGLCGNN 1441 Caenorhabditis elegans
P55155 1380 eeIRVKVDGKKIL-----SE--DYS--AHQIER--LGEsDIVIeLPEGEVR-FDGYT--IKTQLPSYSRKNQLCGLCGNN 1445 Caenorhabditis elegans
O55225  213 ----VTHGGVRVQL----PQVVGGV--QLQQLA---GYvIARH-PSAFTL---AWDGisAIYIKMSPEFLGWTHGLCGNN 275  house mouse
Q28295  100 --GTMLQGTQSISM----PYASNGL--YLEAEA--GYYkLSSE-AYGFVA---RIDGngNFQVLLSDRYFNKTCGLCGNF 165  dog
Q28295  462 --GGVSMDGQDIQI----PLLQGDL--RIQHTV--MASvRLSY-GEDLQM---DWDGrgRLLVTLSPAYAGKTCGLCGNY 527  dog
7A5O_I  153 NGLQSYSEFLSDGV 166  human
P98167 1146 DGDASNDLRSRQGv 1159 cattle
P98092 1758 DGSLANERRLPDGR 1771 domestic silkworm
P87498 1785 DREKHNELLMPNHK 1798 chicken
P02845 1723 DAECEQEYRMPNGY 1736 chicken
P06125 1442 DGERDNEFMTADNY 1455 Caenorhabditis elegans
P55155 1446 DDESTNEFYTSDNT 1459 Caenorhabditis elegans
O55225  276 NADPQDDLVTSYGK 289  house mouse
Q28295  166 NIFAEDDFRTQEGT 179  dog
Q28295  528 NGNRGDDFVTPAGL 541  dog
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