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SagF family protein This protein of unknown function SagF is encoded by the extended locus that includes the key proteins of streptolysin S biosynthesis. Because it is encoded just upstream of genes for ABC transporter permease and ATPase components of an ABC transporter, one group calls the protein a probable ABC transporter substrate-binding protein, designated ScfC (subcutaneous fitness C). However, the protein lacks any readily detected homology to any other ABC transporter substrate-binding protein. Additional members of the family are found in other loci producing RiPP class peptide natural products related to streptolysin S, such clostridiolysin S. |
Jiyao W et al.(2023). "The conserved domain database in 2023.",