Conserved Protein Domain Family
GrdX

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NF038093: GrdX 
GrdX family protein
GrdX is a small protein, of unknown function, encoded in grd operons for selenocysteine-dependent glycine reductase systems. A small number of GrdX proteins appear to be encoded with a UGA-encoded selenocysteine residue appearing close to the N-terminus, at sites that do not align with Cys residues in other members of the family. This arrangement suggests that the ability to complete translation of GrdX selenoproteins may have regulatory value, in addition to whatever may be the molecular function of GrdX itself.
Statistics
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PSSM-Id: 411675
Aligned: 50 rows
Threshold Bit Score: 112.649
Created: 19-Oct-2021
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_009297928   6 TLITNNELVKERYGAygkelnvEYLEDAGCLDVLIKARDAIHGGSRLETHPMAGSIKPNQNPYKTVMISDGKVDpeefQ- 84  Clostridium sp....
WP_014185112   4 LIVTNNPAVAEQRNN-------VLFVDGSVEEVLIKVRDLVHQGYELISHPLGASIRIIFSPFRSIVLGKKSARad---- 72  Desulfosporosin...
WP_005586931   4 RIVTNNPLAKKEFHN-------VCFIEGSYEDVLLKIRDLVYEGLDLISHPLGASMRMLYSPYRSIVVGQKNEAid---- 72  Schnuerera ultu...
WP_009372712   4 KIVSNNSLVKEKFDC-------VEFVDGNYIDVLIATRDLIHKGCSLVSHPLPASIRMVFSSIRSIVIEDGNGFd----- 71  Parvimonas sp. ...
WP_016648362   4 LIVSNNAFVKAKYQS-------LQFVEGDFYQVLIAARDRIHRGWRLVSHPLPASIRMMYSPIRSIILAKE--Ph----- 69  Facklamia hominis
WP_002838759   6 VIVTNNSYVINEYDN-------TINIEGEYLDVLYKVRDLTHLGYSLVTHPLAASIRMFYSPVRSVVMKKG--Fs----- 71  Finegoldia magna
WP_008902183   8 YIVITNNSIFKDRED-------TIYIEGDFIDVLKSVRDYMHKGYLAISHPLPASIRMILSPVRSVIMVDN--YsdqeLy 78  Peptoniphilus d...
WP_006700693   7 AIISNNRLIQDRFEN-------VISIDGDFRDVLLKVRDYIHLNYRPVTHPLPSSSRMFLSPIRTIILTKG--Ml----- 72  Facklamia ignava
WP_006820619   5 LIVTNNPVVAARYAGh------SLSWQANYLQVLLAARDAIHQGQKLLMHPESGSVKPGQTPYRSLLLDGKTSal--dL- 75  Yokenella regen...
WP_008522276   4 ILTNNPDAAEAALAP-------TELVKGTPLDVLTRARELIDQGYFLVTAPLAANNRLNRSPYRSVILSREKSws----- 71  Jonquetella ant...
WP_009297928  85 -EFITVMENSIMTCRKFLMekpLP-EWDEKLKKDFRYIDQSLIESAVS 130 Clostridium sp. 7_3_54FAA
WP_014185112  73 qLSVEIIEDSILKYTRHMAfrnKEtV----AGDDYQMIDLILIESALL 116 Desulfosporosinus orientis
WP_005586931  73 lFHIEIIENSIMNYRKNLEgrkIDwV----HAEDYALIDNELLKSTLE 116 Schnuerera ultunensis
WP_009372712  72 eNSTLIIEEAIDKYNLTMKnrnVDfK----NVKDYEIVDLTLVESALE 115 Parvimonas sp. oral taxon 110
WP_016648362  70 sSATLLIEQSIDSYLRTMGqrqPDyR----NLADYQTIDFELLQACIA 113 Facklamia hominis
WP_002838759  72 eRSIEIIENSIEKYINTMGvrkPDyR----NGEDYCTLDAVLLKEGIE 115 Finegoldia magna
WP_008902183  79 nKTLEIVESSIISYTNTMGirkPDyK----NIEDYKIIDKNLLYSSFD 122 Peptoniphilus duerdenii
WP_006700693  73 sDSIEVIESSIQKYDTTLGerqPDwA----HREDYELIDAELFQSSLA 116 Facklamia ignava
WP_006820619  76 -RSLEMIENALARYRHFSGtgrPLsAWSEQIKCDFQLIDLSLLREALQ 122 Yokenella regensburgei
WP_008522276  72 gDDAALLDMGISHMALQGfs-aAKd-----ADSDYRWMDLSHLKTALE 113 Jonquetella anthropi
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