Conserved Protein Domain Family
msp_porin

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NF033926: msp_porin 
MSP porin
Members of this HMM are MSP porins (major outer sheath proteins) in Treponema. They may play a role in immune evasion and persistence.
Statistics
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PSSM-Id: 468249
Aligned: 10 rows
Threshold Bit Score: -1
Created: 24-Apr-2023
Updated: 3-May-2023
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_010693658   2 KKILSILMILVLVGGV--AFAQL-----TP------------------------QVTASATVNWGIDLg-SGs----kA- 44  Treponema denti...
WP_138561178  34 RRFSLIFFFVVVLGRSprLWAQVs---fTP------------------------DIEGYAELAWGIAS--DG------G- 77  Treponema pallidum
WP_004266454   2 KKYLIAFSIFAFALGI--AFAQEae-aaEPaqkaaaaepakepevyaltsgakaSIEGSTKLEWGIDLg-AGkv--tkD- 74  Treponema phage...
WP_016522943   2 KKYLLVSLTILFAATF--VWAEGat-tvEPs----------------------vDIEADATLSWGFDLgsKTn------- 49  Treponema medium
WP_006188849   2 KKYLLVSLTILFAAAF--VWAADat-tvEPs----------------------vDIEAEATLSWGVNV--EGn------- 47  Treponema vince...
WP_044013922   2 KKYLLVSLTILFAATF--VWAQNaa-taEPs----------------------vDIEADATLSWGIDLgpGG-------- 48  Treponema sp. O...
WP_041610138   2 KKILSILIALVLVGGA--VFAQDapempAP------------------------VFKGSATLSWGIDLg-YGtdkygsA- 53  Treponema pedis
WP_044978071   2 KKILSILMILVLVGGV--AFAQV-----EP------------------------EVRGSATLSWGIDFgaGSetdytkGg 50  Treponema putidum
WP_002692412   2 KKILSILMILVLVGGV--AFAQV-----EP------------------------EVRGSATLSWGIDFgaGSetdytkGg 50  Treponema denti...
WP_010688700   2 KKILAILMILVLVGGV--AFAQL-----TP------------------------QVTAKASVNWGIDFg-AGk----nA- 44  Treponema denti...
WP_010693658  45 -----TPQHGFENKFVAKVIVPLY-MGKL---NSKTEGNVHMNFDI-DLNLAYrfygaksNSaspyvpwGSDAEMALwRK 114 Treponema denti...
WP_138561178  78 -----AIKHGFKTTTDFKIVFPIVaKKDF---KYRGEGNVYAEINVkALKLSL-------ES-------NGGAKFDT-KG 134 Treponema pallidum
WP_004266454  75 -----SIAHGFKNSGSWKVSFPLFeKKSL---TSKADTPVYAEVIIkDVELGI-------ESkydkdskDEDKKFHF-TG 138 Treponema phage...
WP_016522943  50 ----pDFKNGFKNEASWGVNFPLLaKANKt--STKNDVPVYGEITLkNVALNLv-----sEK-------DSGGHFTM-DG 110 Treponema medium
WP_006188849  48 -----TVKHGFKNEASWTVKFPLLkKADRt--STKSDVPVYGQVSLkDVELNVv-----sEK-------DSNGRFAL-DG 107 Treponema vince...
WP_044013922  49 ------VKHGFKNEASWSVKFPLLkKADKt--STKNDVPVYGEVSLtDVELNIl-----sEK-------DSGGHFAL-DG 107 Treponema sp. O...
WP_041610138  54 -----LISHGFLNEATASVSLPFVkSG-----SKKGEGDVYALINLdGVKLGL----------------EADLKEAKaTG 107 Treponema pedis
WP_044978071  51 adnhaVATHGFYNSNNFQIRLPFFkRQSFaggSANKEADVYADVSFkATPVAT--------------------GWTA-TG 109 Treponema putidum
WP_002692412  51 adnhaVATHGFYNTNNFQVRLPFFkRQDFaggSASKEADVYADVSFkATPVAT--------------------GWTE-SG 109 Treponema denti...
WP_010688700  45 -----KAQHGFENLLDAKVVIPLY-MGTL---NSKTEGDVRMNFDL-GVNLAYrfydqlsNSasphvawDSDAEFKLwRK 114 Treponema denti...
WP_010693658 115 TLSGMSASVHFFGGYMNVLGRPDFSTNFAKIWTAITDDG----SEARPETSGDITGFGT-KLGYASDDLAGtglkFDAGL 189 Treponema denti...
WP_138561178 135 SAKTIEATLHCYGAYLTIGKNPDFKSTFAVLWEPWTANGdyksKGDKPVYEPGFEGAGG-KLGYKQTDIAGtgltFDIAF 213 Treponema pallidum
WP_004266454 139 KVDEIVGTLYFYDAYLKIYKKPDFKVNYAQIWDTLKADDw---DKSGYKFEPGFDIAGGtTLGYKKDNIGDsgldLDAGV 215 Treponema phage...
WP_016522943 111 KVDSLAAKLVIYGAYVTVFNKPSFASNYAEIWEPADTDLy---MPEDYRFKPSFGGYGT-KIGYANKDFMD----LDVGL 182 Treponema medium
WP_006188849 108 KVDDLEAKLVVYGAYLTVYNVPDFFKNYAQIWKPIDNDKk--yRAADHRFRGAFDGYGT-KIGYANKDFMD----LDVGL 180 Treponema vince...
WP_044013922 108 KVDGLEATLFIYGAYLTVFDTPSFKANYAEIWLPVDKNKk--yRKDDYKFKPGFSGYGT-KIGYANKDFMD----LDVGL 180 Treponema sp. O...
WP_041610138 108 KIDKVEAKIVFYGAYITVYNAPEMKTKYAADATSLINDDn------fGIFNSGFGGYGT-KIGYANPDLMD----LDVGI 176 Treponema pedis
WP_044978071 110 GAASVKAALHFYGAYMTVYGQPSFEADKALGWNPINWDPn--tDDLNGWFNPAFTGFGT-KIGYKNAGLMN----LDVAL 182 Treponema putidum
WP_002692412 110 KAVSVKAILHFYGAYMTVYGKPDFKANKALGWDPINADDg---DQGKDWFNPAFTGWGT-KIGYKKADLMG----LDVGL 181 Treponema denti...
WP_010688700 115 TLSDMSASIHFFGGYMNVYGRPDFSTNYAQIWSPI-RDNgv---awGPETSGDITGFGT-KLGYASDDLAGtglkFDAGL 189 Treponema denti...
WP_010693658 190 KFGSNGSWKAKGkenaetsakkdykkvalvlgntpvagakyyp-ynaavagvntdgsfvlkdplppaqvftgagGTVA-- 266 Treponema denti...
WP_138561178 214 KFASNTDWEGKD--------------------------------------------------------------SQGK-- 229 Treponema pallidum
WP_004266454 216 KFGSNGNWETEGksdyegspqytlitgpatlakgstyvelepvygkkaeekasyimldnqhfkitsnfkqvspdKDLE-- 293 Treponema phage...
WP_016522943 183 KLGSSSNWAPDDpsaiqhmkhfdgstrleegeyiy-----------------iydpstgfwawlqgggkgtwngDPLW-- 243 Treponema medium
WP_006188849 181 KLGSSSNWDPASashtqtmkyfdgntalgns-------------------------eaiyigdvstgtgtwvtgKQVR-- 233 Treponema vince...
WP_044013922 181 KLGSSSNWKPASksqaqtmkyfdgntmldegef---------------------iyseelggwveggslhgtppAPLW-- 237 Treponema sp. O...
WP_041610138 177 KFTSNGSWKDRDgslgaeyvktvtvkanrvngt--------------------gtvhledgqelrdmsgkvverGPGWkr 236 Treponema pedis
WP_044978071 183 KLASNGSWKQDG--------------------------------------------------------------SDGT-- 198 Treponema putidum
WP_002692412 182 KLGSNGSWHQKA--------------------------------------------------------------SDGK-- 197 Treponema denti...
WP_010688700 190 KFGSNGSWKAKGttsekkeivtlaagdtvdaaakyykfd---------pslftlsadgnlvinlkgktpftfagATVA-- 258 Treponema denti...
WP_010693658 267 AAeAGDylmvtetpakpkstePPfaSKYAIGFDLSLGY--------DKWVTFDFGINATFDpikdf-gaagvDPYveDGE 337 Treponema denti...
WP_138561178 230 AP-AGV---------------TP--SKYGLGGDILFGWertredgvQEYIKVELTGNSTLS-----------SGY--APA 278 Treponema pallidum
WP_004266454 294 VK-EGKyyakvdg--ltkkaaTK--NRYGMGFYTSVAYkp----gdLKYIGFNFDINTTFC-----------SHKdwENN 353 Treponema phage...
WP_016522943 244 FPpAGDyyftat----kkgdvTV--YHYGIGFDFSMKp-------lDKMLAFALTVNSTFG-----------KQYkkVd- 298 Treponema medium
WP_006188849 234 FPdAGWyyfvkk----nsadpTT--YQYAIGFDLSMKp-------lDKMLGLAFTVNTTLS-----------KNYp---- 285 Treponema vince...
WP_044013922 238 FPePGYypfvtk---adgdskTD--FYYGLGFDLSMKp-------lDKMLAFALTVNTTLS-----------NQYd---- 290 Treponema sp. O...
WP_041610138 237 VP-SGQymiyrs---ayyryrMN--GHYGLGIDFHMAp-------vEKYLTVDANFNMTFDt---------aGSYrtDVE 294 Treponema pedis
WP_044978071 199 KPwDGTsgnk--------rreKD--SKYAFGLDFSMQp-------vEKYLGVEATVNATLGrlsnkatlnnpDDYgyNTG 261 Treponema putidum
WP_002692412 198 ---DGKrr------------eKD--SKYAFGLDFAMEp-------vEKYLGVEATINATLGkffnktplenpGDYgyNAG 253 Treponema denti...
WP_010688700 259 AGeAGQyvkvtt----tatgsAA--NKYAFGLDLSLGY--------DKWVTLDFGINATFD-----------NVKdfGKA 313 Treponema denti...
WP_010693658 338 TPSNv-------kKAYIGTGFKLGSKpVDGLALNFGMDTlmNVGN-------DSKPAFDIVFDASYK-----WVKAGVYY 398 Treponema denti...
WP_138561178 279 QPPA---------NILWDVGAKVSMK-LWGLCALAATDV--GHKKdg----aQGTVGADALLTLGYR-----WFSAGGYF 337 Treponema pallidum
WP_004266454 354 TEKGn--------YFNVSFGTKITSEpVKDLSLVLAFD---GEPFvn----gEKKFAWDMLFDTTYK-----WVGAGVYV 413 Treponema phage...
WP_016522943 299 -------------DGLLNLGFEVTSEpVDGLKLKAGFDG--KYVFd------KKAFDWDTVFTAEYK-----WVGAGVYV 352 Treponema medium
WP_006188849 286 -------------DANLNFGVEATSEpMDGLKLKAGFDG--MYDFka----aSNAFNWDTVFTAQYK-----WVGAGVYV 341 Treponema vince...
WP_044013922 291 ------------tNHNLSIGAEVTSEpMDGLKLRAAFDG--GLKYt------SRVFNWDTVFTAEYK-----WIGAGVYV 345 Treponema sp. O...
WP_041610138 295 SNFDd--------MRVMNVGAMIKSEpIDGLMFKLGFDG--GHAFkkasdasAPLFAWALGFGTEYKdsragTINAGLYV 364 Treponema pedis
WP_044978071 262 ITPTnvgg-ekgeSGMVNFGVAFTSEpIEKLTVKLGFDGvtGVTYtde-gktKETLGWDAGLSVGYK-----WVDAALYF 334 Treponema putidum
WP_002692412 254 NVPAnigg-kegkSGMVNFGLAFKSEpIEEMTVKLGFDGvtGLTYtdnegkiQETLGWDAGLSVGYK-----WVDAALYL 327 Treponema denti...
WP_010688700 314 GVHEdvaagsnpdKPYLGMGLKLGSKpVDGLALTLAMDAlmNVGT-------DSKVAFDLRFDASYK-----WVALGAYF 381 Treponema denti...
WP_010693658 399 GNELSNYagMD------KD--GKAIGDMAAML-AFSSEGSGD---------------TNFLEGLAFGVDFRLNHMLTAIS 454 Treponema denti...
WP_138561178 338 ASKASNV--FKdv--flNM--AMTAHDCAAYI-KLETKGSDPd--------------TSFLEGLDLGVDVRTYMPVYYFA 396 Treponema pallidum
WP_004266454 414 GNENTFY----------KS--NKDGVDMSIYA-KFETKGD-------------------LVKNLNAGTALYVHRLLSKPE 461 Treponema phage...
WP_016522943 353 GSAGTPIgks----lsgLP--ADNRTDMAVFA-QFATKGDKEd-------------aTNLVEGLDAGVYVGMYKLLDKAH 412 Treponema medium
WP_006188849 342 ASADTWMgn------nnTS--HANRTDMAVFA-QFATKGDKGd-------------aTNLVEGLDAGAYISMYKLLYGLS 399 Treponema vince...
WP_044013922 346 GSAGTPI--------------GNGRTDMAVFA-QFVTKGDKKd-------------aTNLVEGLDAGVYVGMYQLLGAS- 396 Treponema sp. O...
WP_041610138 365 SSDGTPYg-NAgifdpyKL--NFVPDGKGGFKeEKRPDGTRPgrgitdiaftvgysgLPAVEGLDLHARLNVFGLLSKIS 441 Treponema pedis
WP_044978071 335 AGTGTKYqgYNiagddpTKf-KNHGINMAAHL-AFVSEAEGD---------------TNLVPGLAFHATVNAYDLLAKRS 397 Treponema putidum
WP_002692412 328 CGTGTKYqgYNvagndhTKw-KNYGANMAAHL-GFVSDEEAKk-------------gTGFVDGLAFHVTINAYDLLAKRN 392 Treponema denti...
WP_010688700 382 GNDLSAYa--------gKDknNKAIGDMAAMI-AFKSAASGD---------------TNFVEGLAFGVDFRLNHLLSAVP 437 Treponema denti...
WP_010693658 455 DAD-------------------------------------------------------KKNSVIMPMGLKSWVSYKRNLT 479 Treponema denti...
WP_138561178 397 ARAra---------------------------------------------------gaAVPAIYFPVYGKVWGSYRHDMG 425 Treponema pallidum
WP_004266454 462 NEK------------------------------------------------------------TYPIGLKVYADYKYDIN 481 Treponema phage...
WP_016522943 413 ---------------------------------------------------------------KFPFFAKVWGAYTVNIN 429 Treponema medium
WP_006188849 400 DVK------------------------------------------------------------KFPLLVKVWGAYKVNLN 419 Treponema vince...
WP_044013922 397 ---------------------------------------------------------------KFPLFAKVWGAYKININ 413 Treponema sp. O...
WP_041610138 442 KEE-------------------------------------------------------RAMGELIPLGLNVGAGYKAMLT 466 Treponema pedis
WP_044978071 398 TQDmdkslrqalagllnagptati-------------piipglttatttyadllelalRSKYAQLPMGFNLGASYKYSMT 464 Treponema putidum
WP_002692412 393 SEDipeatrkanigalstydaaltayleanpnkteadfqadpanaavvnafkvakalfKTKYASIPLGLNLGVSYKYDLT 472 Treponema denti...
WP_010688700 438 TGD----------------------------------------------------------KSTLPMGISAWVNYKYALT 459 Treponema denti...
WP_010693658 480 DSMWIKPYAAVWAESNHDK---------YADGTSSSKNYFGvVYEVGTTFSPMEKVEIDAKWSHGATEDNWYEgykqqd- 549 Treponema denti...
WP_138561178 426 EYGWVKVYANLYGGTNKQAaav----pgVVPGTKWKAEYCG-YYECGVVVSPLEKVEIRLSWEQGKLQENSNV------- 493 Treponema pallidum
WP_004266454 482 DSMWLKPYASFYGETNHAE-----------------PKF-GvYYNVGLTFSPLERLELTADWEQGKVVKNKHEg------ 537 Treponema phage...
WP_016522943 430 DSMWIKPFANLWLETDHGT------------------QAVGlAYNLGVTYSPVEKVEVTAKWSHGKINTDTHNg------ 485 Treponema medium
WP_006188849 420 DAMWVKPFADVWVESDAKH-----------------GNSIGlAYDLGVKFSPVEKVEVKAAWEHGSINKNAYSsatqrky 482 Treponema vince...
WP_044013922 414 DSMWLKPFADVWLETN--H----------------GSSAVGlAYDLGVKFSPVEKVEVQAKWNHGSITKNKYLg------ 469 Treponema sp. O...
WP_041610138 467 DSIWIKPYADLWGETNSDIy-------sDDTPKSKQKLYFGlAYKVGLSVSPMERLTIDLNWSHGKAFNPDVLmgtgsm- 538 Treponema pedis
WP_044978071 465 DVMWVQPYAEFYAETNHFAqhad--tyaSDPDKVIDKLYLGmAYEIGVKFQPIEKVEVKASWEHGKLNENKYEagfn--- 539 Treponema putidum
WP_002692412 473 DSMWIKPYAEFYAETN--HykqhadtyaGDPDKMIDKLYLGmAYELGVKFQPIEKVQVKASWEHGKLNKDTYEgsfn--- 547 Treponema denti...
WP_010688700 460 DSMWVKPYANFWGETNRKS-----------IDASKTDKFFGvAYKVGATFSPAEKIEIDTYWSQGKLSWNKYEgt----- 523 Treponema denti...
WP_010693658 550 kkglhsMIKTPAnykNHNGTFVIGVKVKY 578 Treponema denticola
WP_138561178 494 ------VIEKNV---TERWQFVGACRLIW 513 Treponema pallidum
WP_004266454 538 ------FIEKSAg-kEHNGRFKLSCKVSF 559 Treponema phagedenis
WP_016522943 486 ------IIKASVidsEHRGRFVLSLKVSY 508 Treponema medium
WP_006188849 483 kkdyvsVVDHSVldsTFYGQFVLSLTLTY 511 Treponema vincentii
WP_044013922 470 ------VINKSVidgQHYGAFVLSLKVAY 492 Treponema sp. OMZ 838
WP_041610138 539 -fglgqWRSTPFqhkADNGRFVVSAKITY 566 Treponema pedis
WP_044978071 540 --ggdyMIGTPInnkSHNGTFVLSLKLTY 566 Treponema putidum
WP_002692412 548 --ggeyMIKTPLnhkMHNGTFVLSLKLTY 574 Treponema denticola
WP_010688700 524 ----egMISAPAf-dAHNGTFVIGVKVIY 547 Treponema denticola
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