Conserved Protein Domain Family
AcfA_fam_omp

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NF033908: AcfA_fam_omp 
AcfA family outer membrane beta-barrel protein
AcfA (accessory colonization factor A), as discussed in Vibrio cholerae, is a porin-like outer membrane beta-barrel protein. It encoded in a locus with other proteins also termed accessory colonization factor, near the toxin-coregulated pilus genes, and its presence aids in intestinal colonization, but its molecular function is unknown. Members of the broader family, described by this HMM, are found in many species of Vibrio, Photobacterium, Aliivibrio, and related genera. The name AcfA is used also for a member of this family from Vibrio alginolyticus, that is no more than 40 percent identical in amino acid sequence, but it is unclear that all members of this family should be considered AcfA.
Statistics
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PSSM-Id: 468238
Aligned: 40 rows
Threshold Bit Score: -1
Created: 24-Apr-2023
Updated: 3-May-2023
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_115137376   2 KKRLLlpLLVMSPAVFAAPnsdveydvtavevdspngvevmavgdevqlpvksnsgiYAGLEYGIGAVEQDYHTNFAGDN 81  Shewanella cora...
WP_105061691   2 KKSVLlsLAFLSGSAVATP--------------------------------------YMGLEYGSASVKHDYQTHFLADN 43  Photobacterium ...
WP_068945989   2 KKHLLaaLLCTSSSAMAAP--------------------------------------YVGLDLGLSTFSHDYQTHFSADN 43  Photobacterium ...
OCH43078       3 KKICLmaIMLSSSSVFAST--------------------------------------YVGLEYGISSVDSKYNTYFLDDN 44 
WP_065593924   2 KKYLFllMAATSTTAFSAP--------------------------------------YVGLEYGVTNMNHDYSTTFSETA 43  unclassified Al...
WP_017021240   2 KKYVFllMAATSTTTIAAT--------------------------------------YVGLEYGVTSIDHNYSTTYSADS 43  Aliivibrio
WP_067411160   4 KALIAvpALMLSGVVMAQP--------------------------------------YVSLGYGYNALSHDNSVAFSDGT 45  Enterovibrio co...
WP_054673777   3 KLLLAlpVLAVSMAASAQP--------------------------------------YVTLGYGYNSLSHDNTVSFSDGT 44  Photobacterium ...
WP_028305116   2 KKYLPlvLLLTSPTLLAEP--------------------------------------YMQLGMGLIELDHDEDVLFSDGT 43  Oceanospirillum...
WP_068546101   2 KKIIPf--IALLSPAALANt-------------------------------------YIGIEAGTADVKSEESITSKDGA 42  Thalassotalea c...
WP_115137376  82 --VNLKPGGRTDVGGAFIGYRfDNNFGVEFGYNQYk-AKDSFGKnmGTTDHVFTEgkpgvsATHERDWSANTKAHQYIVK 158 Shewanella cora...
WP_105061691  44 --KTVVASDSSSVFGGFIGYKtENNYGFEVSYKQF--DLDGESS--Q-LLLSDKPg-----FILEREWESDLSVKQISLK 111 Photobacterium ...
WP_068945989  44 --KAVSPDDSGMVLNGYVGYR-WDEFGLELGYRHFd-ELDGSSS--QFMGNVDg-------FRHEREWDADLKVSQITLK 110 Photobacterium ...
OCH43078      45 --VSLSPSETSDSFGGFVGYK-LNTFGFELGYRQY--DADASRTqfEGITGAAPNk----qYKEETEWNADVSAKQLTFK 115
WP_065593924  44 gdVTLTPDDSNSAFGGFVGYR-FNDFGLELGYKKF--ESDDSRS--KTINYNPP-------VETEREWNADLDATQFTFK 111 unclassified Al...
WP_017021240  44 --VSLSPDDSSDTFGGFIGYR-INDFGLELGYKKF--ESDDSQS--KMINPSEQAg-----FSQEREWDADLDATQLTVK 111 Aliivibrio
WP_067411160  46 t---LTPDSSDNIWAGTLGYRfDNNFGVELGYRQFdaNDSRSKVisv-----------vnnTQTEDEWDADLKAKQFVVM 111 Enterovibrio co...
WP_054673777  45 n---LKPDSAESVAKAALGYRfENNLGVEVGYSQFdaDASKSKTvsv-----------vgtTVTEDEWDADFKAKQLTIK 110 Photobacterium ...
WP_028305116  44 a---LTPDSQESAFQITVGKRyEK-FGVEVSYRRFegDDSKDVSmySNLPALPSGvvggtpNEYEEDWDSSLKAQQLALK 119 Oceanospirillum...
WP_068546101  43 i--DITPEGSDTVIGGFIGYKfENNWAVEFSYSQFs-SE-DSITnkELNQG----------IVVEQELDAEFDANQFALK 108 Thalassotalea c...
WP_115137376 159 PVYFMPLNDKLTLKTGLGLVLTQYSYHAGSEDEFEAVTNDDLEQTI---TRAGGAHHteNAVGGIASVGLNYNVYKG--- 232 Shewanella cora...
WP_105061691 112 PVVFYSLSENIQLKSGLGLTYSHYKYTSSSHDEYEHVLNDDIEINL---PRSGGESKkdSALGIVASIGVDYNLYRN--- 185 Photobacterium ...
WP_068945989 111 PVYFYALTDRVELKTGLGLTYTQYDYRSGSSDEYELITNDDIEHNV---NRAGGENKknNEFGVIASVGVDYRIWQQ--- 184 Photobacterium ...
OCH43078     116 PVYFYKINPKLQLKTGLGLTYTQYKYKSSTHSEYEMLVNDDIEYRT---PRAGGETQkdNVFGMIASIGLEYNVIDR--- 189
WP_065593924 112 PVYFYNFNEKLQLKTGLGLTYTQYKYDSSAYTETENDLTDQESIS----DHEHGASKseSVFGAIASVGVEYMVMPS--- 184 unclassified Al...
WP_017021240 112 PVYFYNFNDKLQLKTGLGLTYTQYKYNSSSQDEFELITNDDIESTK---NRSGGESQkdTVLGGIASVGIEYMVIPN--- 185 Aliivibrio
WP_067411160 112 PVYFHDVTDKLRVKGGVGLTYTTYKTTGSVSRETENEVTDTESSIShpsISVSNGQKteNSVGMALNLGTEYEVYDG--- 188 Enterovibrio co...
WP_054673777 111 PVYFFDVTENLSIKGGLGLTYTDYKMSGSSQRETENEVTDVESSTAipgVTNP-ASKsqKELGVTASIGAEYRVYQG--- 186 Photobacterium ...
WP_028305116 120 GIYFHDLNEQITLKGGLGLTYTDYELKSSHTQSWEEDKAGPDWEYDn---VISHDKAsdTAWGGIVSLGADYVLMPEtap 196 Oceanospirillum...
WP_068546101 109 PVYFYPLSENLTLKASLGITYTQYEFSSSYEIEYDSVLDVMDIDIPv--AKSSNDDD---AFGGIVSVGLEYNVWDN--- 180 Thalassotalea c...
WP_115137376 233 -LDLGVAAQYQFDHVGNVSELLFSATYQF 260 Shewanella corallii
WP_105061691 186 -IHIGAAMEYYVDNIANGGNITVNTSYFF 213 Photobacterium angustum
WP_068945989 185 -LHIGAGVDYYADSQANAATFMLTSRYQF 212 Photobacterium damselae
OCH43078     190 -LFLGASASYQLDNMANTSSLTLTSAYYF 217
WP_065593924 185 -LALGASASYQVDSIANSTSFMLSSAYYF 212 unclassified Aliivibrio
WP_017021240 186 -LALGASASYQVDNIANSSSFMLSSAYYF 213 Aliivibrio
WP_067411160 189 -LYLGANAGFQFDDVANNTQLLgTVAYYF 216 Enterovibrio coralii
WP_054673777 187 -LFLGAEASFNHDSVANASQVLgTVTYRF 214 Photobacterium sp. JCM 19050
WP_028305116 197 nLTLGVEGSVAIDEYSTVSALLgNVGWKF 225 Oceanospirillum maris
WP_068546101 181 -LNLGANVKYQQDSIASNTQFNISASYYF 208 Thalassotalea crassostreae
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