Conserved Protein Domain Family
deAMP_SidD

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NF033871: deAMP_SidD 
deAMPylase SidD family protein
The founding member of this protein family, SidD from Legionella pneumophila, is a type IV secretion system effector that acts as a deAMPylase of the host protein. Homologs are found in several other Gammaproteobacteria, including several different Legionella and Coxiella species.
Statistics
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PSSM-Id: 411435
Aligned: 8 rows
Threshold Bit Score: 184.906
Created: 19-Oct-2021
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_133136422   4 LITQVCNGVLHEEVYRSRPNALDHGNSEVLASSLFihfdeEGKSIAKPKNSDDKLVIGYtQEGMA-FQIIVDGFYGGERQ 82  Legionella rowb...
OGT46836      11 ILSTTASDQVSAVAYHENSVLAQMNLGEIRAANLW-----KSNRKSSKENMDDMACIVY-HDGLP-TIIAADGAFGCEAQ 83  Gammaproteobact...
WP_059428590   4 IITQICNGVVHGHTYHSSRNDLDKGNSEIFASSLFvhlneEGKDIAKPKGSDDKIVIGYtKDGMA-FQIVVDGFYGCERQ 82  Legionella pneu...
OGV50939       4 LIVQNCNGVTAGKTYRSELSTLDEGHSQVYASSLFvrlneKGEDIAGPKETDDKIVIAYtYSGMV-FQIVTDGFYGCERL 82  Legionellales b...
PHQ80257       4 IVIQSAQGATKESPIYNQTCGFDADNSHIEAGSVFar-fyKGKEIPNKKPSDDKIIIGYlSNGLP-FQIIVDGSSHGKTN 81  Coxiella sp. (i...
WP_115302033   3 yIIQQCE--RSQTPITTRRTFIDDRHSTLQAGSCFes-vvDGEIVTKSKPSDDKIVMGYtDKGLP-FQIVVDGFFLGATQ 78  Legionella beli...
OGT34927      20 LIAQQLDGVKAGKVVKQCRNELDPLGSCLYGTSVFah-fdHGKQTEKTKDTDDKIVIGYtCDGLP-FQIVVDGFYGGETK 97  Gammaproteobact...
TAL57794       4 ILTQEHYSRSAG-TYHASKSPVDKGDSHIFAS--------RGK---GSKQSNN-IVIGYlTSGYStFQLL---FHGPKSD 67  Legionella sp.
WP_133136422  83 ATFaFIDNHVVS-LMERYSTELSTasaEKTPQD---ITEQLIHTIY-SLRLRH-AINSEFTMSLSMMYQKE--DAFYCAG 154 Legionella rowb...
OGT46836      84 HIH-FITTEIIPaILTTFISKLSIaksEAEKKA---VLESIFKAINkAVLQQYgLATASFVFSLAMIYQDKltGEIKVAG 159 Gammaproteobact...
WP_059428590  83 AVFsFIDNHVLP-LIDNFALDLAR---YPDSKK---VTKSLIHTIY-SLRSKH-APLAEFTMSLCVTYEKN--DQLFCAG 151 Legionella pneu...
OGV50939      83 TVFnFIDTYIVP-LMEEYSNELMI----KNPDR---VTSELIKRIY-TLYNKH-NHGAEFTLSIAMTYPKE--GAIRCAG 150 Legionellales b...
PHQ80257      82 QTFrAIDQYIVP-LVAKYSVALGT---ADHHKD---CIRALIDEIF-TLRENK-FRACDFTMSMAIGYKKN--EELKIAG 150 Coxiella sp. (i...
WP_115302033  79 KTHqFITDYVTT-LIDDYAKDLEIg--DANANE---VTSNFIDKIY-ELRAEY-ASDAEFTMAVAVTYEKD--GQLWCSG 148 Legionella beli...
OGT34927      98 KTFeFIDKHVTP-LMDNYAEKLSK---NNDPEE---TIKDLIRTIY-TLRATH-STGSEFTMSIAITYQKD--SRLYCAG 166 Gammaproteobact...
TAL57794      68 HNVdFIRKSILP-KIENLKL--------TDPESaffVMHNLLESIIkEHKTSH-LSGLDFKLGFAITYSYP--SHAYCTG 135 Legionella sp.
WP_133136422 155 FGIGDTGIAIKR-IDGTIEQLTYHTEV-----DGS-KDAF 187 Legionella rowbothamii
OGT46836     160 FGTGDVTIVARK-QTGEVDVLKPAQRI-----IDI-HSAY 192 Gammaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_38_11
WP_059428590 152 FGIGDTGIAIKR-NEGTIEQLVCHTEV-----DGF-KDAF 184 Legionella pneumophila
OGV50939     151 FGIGDTAIAIKR-TNGKIQQLVAHAEV-----DGF-KDAF 183 Legionellales bacterium RIFCSPHIGHO2_12_FULL_42_9
PHQ80257     151 FGIGDTGIILQRaDDHEIIPLVQTSTV-----AGFkKDAF 185 Coxiella sp. (in: Bacteria)
WP_115302033 149 FGIGDTGIAIKRkNNNQIEQLSFNQEVtynrhDPF-KDAF 187 Legionella beliardensis
OGT34927     167 FGIGDTGLILQK-SSGETQQLAYTTHV-----NRF-KDAF 199 Gammaproteobacteria bacterium RIFCSPHIGHO2_12_FULL_37_14
TAL57794     136 FSFDGIKVCIR--TKGTNKLSFNSDEP-----SRYsYTNF 168 Legionella sp.
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