Conserved Protein Domain Family
SMEK_N
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NF033859: SMEK_N 
SMEK domain
The SMEK domain is named for four genera in which multiple, diverse members of this uncommon family of bacterial proteins are found: Staphylococcus, Mycoplasma, Escherichia, and Klebsiella. Members of the family are highly variable in length. This domain occurs as the N-terminal region. The four scattered invariant residues in the seed alignment, which may provide a clue to function, are Glu, Asp, Gln, and Lys.
Links
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Statistics
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PSSM-Id: 411427
Aligned: 65 rows
Threshold Bit Score: 88.3465
Created: 20-Oct-2021
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_007833955   3 ESLIKNLNQDIALLQLRIERDKDAGFNDMARLLESMSIQFFKAVGIANLKSKNQIRVNFPAIDAADDDKDggIAVQVTSV 82  Variovorax sp. ...
WP_004099064  17 MKNRDKLVSFAVTLASQIKMYTRSNHNDISIAQENSLLPLINYAWGKQFENMNKVLKNHPGCDYWKPVER--LGLQMTAI 94  Klebsiella mich...
WP_000796111   1 MKNREELTSFATKLATQIKMQTSSNLNDLSTAQESSLLPLINHAWGEQFEDMNRISQNYPGLDYVQPGKR--LGLQMTAT 78  Escherichia
WP_001618761   5 KASQDNVSFGLAVLKYYLRFNSKNNLQDANVTAEELVSKLVNILKDTKFLCTAEIKSNFPGIDALDENKR--LGLQISHE 82  Enterobacteriaceae
WP_020324021   5 MQLINELEHDFSVLTSYITSQNSRGLTDINKEMEEYLLPILNVVYKANLINLNKFKYNYPAIDLGDIKSK--RCVQITST 82  Klebsiella pneu...
WP_017345796   3 DPLIRNLQSDISVLQYYINQRQKAGFHDMERMLESLTIFIFRALRKGNLENLNQIKVNFPAIDLADQENK--VAVQVTTN 80  Pantoea sp. A4
WP_001575456   3 DPLIRNLQADIALLQLYIAQRQKTGFHDMERMVEALTIFMFRALQMGELKNLNQIKANFPAIDLADNQKM--IAVQVTTN 80  Enterobacteriaceae
WP_001559332   3 APLISNLQKDIALLQLYIEQRKQTGFHDMERMIESLTIYMFRALKMGELENMNQIKVNFPAIDLADNKNM--IAVQVTTK 80  Escherichia coli
WP_000566845   3 DPLIRNLQSDIALLQLYIAQRKQAGFHDMERIIESLTIFMFRALKMGELVNMNQIKVNFPAIDLADNKNM--IAVQVTTN 80  Escherichia coli
WP_015959329   3 DALIRNLQRDIALLQLYIAQRKQAGFHDMERMIESLTIFMFRALKMGELENMNQIKVNFPAIDLADNQNM--VAVQVTTN 80  Klebsiella pneu...

WP_007833955  83 ADAKKISKTITTFEKKDAA 101 Variovorax sp. CF313
WP_004099064  95 VAKKKYQDTLEKLRNNNRL 113 Klebsiella michiganensis
WP_000796111  79 ARKVKYQKTLDKLRNNEKL 97  Escherichia
WP_001618761  83 NTSKKINETIDVIRNNNVN 101 Enterobacteriaceae
WP_020324021  83 SGKTKFDKTIEKFISHNIN 101 Klebsiella pneumoniae
WP_017345796  81 ASPSKIDKTIEALEKKNLS 99  Pantoea sp. A4
WP_001575456  81 ASPAKINKTIEAFEKKNES 99  Enterobacteriaceae
WP_001559332  81 ATPAKIKKTIAAFEKENKS 99  Escherichia coli
WP_000566845  81 ASPAKIKKTIESFEEANEI 99  Escherichia coli
WP_015959329  81 ASPTKIKKTITAFEKTNDL 99  Klebsiella pneumoniae
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