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variable surface lipoprotein signal domain This HMM describes a homology domain of lipoprotein signal peptides restricted to the genus Mycoplasma, and found in paralogous families that typically are associated with antigenic phase variation, as expression of some members of the family is turned on, others turned off, by the means promoter region modifications by site-specific DNA invertases. The avg family of Mycoplasma agalactiae represents one such family of lipoproteins.
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