Conserved Protein Domain Family
MG406_fam

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NF033688: MG406_fam 
MG406 family protein
Homologs to MG406 from Mycoplasma genitalium and MPN605 from Mycoplasma pneumoniae are about 150 amino acids long on average, highly hydrophobic, widespread in but restricted to the Mollicutes, and highly divergent there. MG406 itself appears to be an essential gene.
Statistics
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PSSM-Id: 411284
Aligned: 47 rows
Threshold Bit Score: 46.4162
Created: 24-Apr-2023
Updated: 3-May-2023
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q49431         3 NWNNRKv--AKIIT--LIIFVAWLFVLILIAVVVLTKGNNLDILFGWMLPLPFAVLNSLSVLRLASFFAS---LKNvkk- 74  Mycoplasmoides ...
OSY17843       6 LAQKWKqtnNRWLVvgLVSLMVITSLILIILITTKTTIVNWSWIIGYVVAFFCSTTALFSIYYAYKVLMR---TEN---- 78 
WP_027123886   1 MFSKKH---SKWLF--ITYGSFVLLGLVILLVVCGTNLASWGSLYGWLLSIPFAFIAIFSYTWIPRILLS---LSKkrig 72  Mycoplasmoides ...
WP_041614418   8 NWKNRFkgvECKMS--LISIIMLFGALIVLTVLYFSVDMSWNIYTGLGLGYLFSLIGFLIIIWSWWLLSI---SLN---- 78  Spiroplasma syr...
WP_047790990  10 IWKNKFkgvEYKMS--MISVIALFGILIIVTILYLTLKWSWTLYSGLMLGYLFSLIGFLIILFSGWLLSI---SLN---- 80  Spiroplasma eri...
WP_053391465  10 NWKNHFkgvEYKLS--IISLIMFLGILIVLTMIYLTLKRDWTLYTGLVLGYLFSLIGFLIICFSGWLLSI---SLN---- 80  Spiroplasma kun...
WP_033160260   1 MFNTKQ---TKWLF--LIYSGLCFIGIIVLLIICGLNLTPWGSLYGWLLVTPFAILAMISYTLIPNFLLN---YSKkkke 72  Mycoplasmoides ...
WP_027119813  18 SSTSD----LAWFFknLSYLGFALLGIIILIILGVTNTAPWGTLYAWLVGLPFGIVAVFSSTVIPKFLMSlslKLSkktn 93  Mycoplasma test...
WP_010874962   3 NWTNKKl--TKAIA--LIILVLWLVVLVGILVWALT-TQHLKVLYGWLLPFPFVALSVVGLLKLGDFFEK---FKHlsk- 73  Mycoplasmoides ...
WP_027121993   7 IIKCN--------L--IAFNALSILALIILLALIFSKIIGLQWFYSGLLTLVFCNISLVIGLIVPNLLYK---SATklnm 73  Mycoplasma imitans
Q49431        75 ---qkaVSFFA---FFFTA----RYLIYLIPVIISFVVtPSIFNTIAtiistlFfpILNLVlSFVWLPleyFFIN 139 Mycoplasmoides genit...
OSY17843      79 ------YYTYL---FLFIS----RFGLYFIPFILAVFIpGDKISVFG------V--LIGFT-PIILLP---LFQG 128
WP_027123886  73 dkskavLFLSI---SLYIL----RYIFYITPILIAAGV--NNFKIDG------VfnVIPTIvAIILIPissIALN 132 Mycoplasmoides pirum
WP_041614418  79 ------KFLFV---LLYFF----RIFIYLIPIVIFVKA-PNSFSIIT------L--AIGLV----IYPlsaLLVN 127 Spiroplasma syrphidi...
WP_047790990  81 ------KYFFV---LMYLV----RLMIYAIPIIIYAYW-DEYFNIFT------I--IIGLS----IFSfsaLFLN 129 Spiroplasma eriocheiris
WP_053391465  81 ------KYFFI---LLYLV----RLVIYAIPIVIYAEN-TSFFSIYT------I--IVGIS----LCPfssLFAN 129 Spiroplasma kunkelii
WP_033160260  73 qqnkviMSLSI---LIYIL----RYIFYALPILIAGGI--NGFKLEG------VfnVIPTIvAIILIPissIVVN 132 Mycoplasmoides alvi
WP_027119813  94 shkrgaMFFSTiggFLFIG----RYFLYIIPIIIVAAV--NNFQVDG------IfhIAGVVaVVALVPtnsIFLN 156 Mycoplasma testudinis
WP_010874962  74 ---qrvTVFFG---SFFVA----RYLLYLIPVLLAFFIrPQYFHVIAtiistlFfpLLKIViSFAWLPleyHCKN 138 Mycoplasmoides pneum...
WP_027121993  74 kqvkstRFGFF---IFGVLtlcsRIFWYVIPIVIIGVM--NQWQFQG------K--VFNVF-PAILWPlsmIGIH 134 Mycoplasma imitans
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