Conserved Protein Domain Family
Tet_leader_L
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NF033685: Tet_leader_L 
tetracycline resistance efflux system leader peptide
Stalling of the ribosomal translation of a tetracycline resistance system mRNA from inability to properly translate a short leader peptide can affect mRNA secondary structure, preventing early transcriptional termination and therefore inducing expression of the resistance protein. This leader peptide is found upstream of efflux transporters such as tet(L) and tet(45) (which occur in Gram-positive organisms), but on occasion may occur as a fused additional N-terminal domain of such efflux proteins.
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Statistics
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PSSM-Id: 411282
Aligned: 15 rows
Threshold Bit Score: 25.8957
Created: 24-Apr-2023
Updated: 3-May-2023
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_108308367  2 MKCNECNRVQLKEGSVSLTL 21  eubacteria
WP_013762478  1 MKCNECNRVQLKEGNVSLAL 20  eubacteria
WP_010886645  1 MKCNKMNRVQLKEGSVSMTL 20  Bacillus subtilis
AAO64466      1 MKCKKMNRVQLKEGSVSMAL 20 
WP_106503097  7 MKCKKMNRVQLKEGSVSTAL 26  Bacillus amyloliquefaciens group
WP_115940658 26 MKCEKMNRVQLKEGSVSTAL 45  Bacillus
WP_108490746  7 MKCKKMNRVQLKEGRVSMAL 26  Bacillus
AAO64463      1 MKCKKMNRVQLKHASVSMAL 20 
WP_111909810  2 MKCNKMNRVHVKEGSVSMAL 21  Bacillus tequilensis
AEM62954      1 MKCNKYNWVHLKRVSVSMTL 20
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