Conserved Protein Domain Family
ExeM_NucH_DNase

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NF033681: ExeM_NucH_DNase 
ExeM/NucH family extracellular endonuclease
Statistics
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PSSM-Id: 468139
Aligned: 161 rows
Threshold Bit Score: -1
Created: 24-Apr-2023
Updated: 3-May-2023
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_017095849  226 VTGVVSAVTK-----SITKGFYLQALEDDYN--AKTSEGLFVe---TGSSdTGLSPGDVVCVKGKAHELFNRTQLK---S 292  Vibrio
WP_001981579  224 VKGVVSAVTT-----GLTKGFYLQSLEDDYN--PNTSEGLFVf---TNQSsSDLAPGDVVCVKGKVQEYYNLTQLK---A 290  Vibrio cholerae
WP_013855897  228 VKGVVSAITT-----GLTKGFYLQALEDDYN--LNTSEGLFVf---TDQSsSSLKPGDVVCVKGKVQEYYNLTQLK---V 294  Vibrio anguil...
WP_017083792  225 VKGVVSAVTT-----GITKGFYLQALEDDFN--SSTSEGLFIh---TNQSsSELAAGDVVCVKGKVQEYYSHTQLK---V 291  Vibrio splend...
WP_006878363  227 VKGVVSAVTT-----GLTKGFYLQALTDDYN--PETSEGLFVh---TNQSsSDLKAGDVVCVKGKVQEYYNHTQLK---A 293  Vibrio brasil...
WP_006963247  223 VKGVVSAVTT-----GLTKGFYLQALEDDYN--PKTSEGLFVh---TNQSsSDLQPGDVVCVKGKVQENYNLTQLK---A 289  Vibrio
WP_020333825  210 VTGIVTAIQTsalgnDLPVGFFLQDQYGDGN--ENTSDAIFI----RGDI-SGIEVGNTVTVQGKAYESYGWTQLIdthV 282  Vibrio natrie...
WP_019615420   56 VKGLVTAIQTkklgkDLPVGFFIQDKDGDGN--PKTSEGVFVdatyNKDTvlGLSVGDKVEVTGKVKESYSWTQIVgteD 133  Psychromonas ...
WP_019613126  214 VEGIVTTld-------yaGGFFIQDEAGDDN--PLTSDGIFV----IGST-TGLSVGDKVAVTGKIKEDYGWTKLD---S 276  Psychromonas ...
WP_014979146  243 IEAIVTG--T------RAGGFFVQEEASDYDadDATSEGLFV----EGSV--DVETGNLVRLYGEVEENYGMTTLAmdsD 308  Alteromonas m...
WP_017095849  293 DA---NSFVKQSsqaAPTAVE-FVVADSETLHqaLERYEGMNVEL-SadSKLFVTRNFSYdyaGRRNNMVLAHEKPLM-K 366  Vibrio
WP_001981579  291 EN---NQWVKQGqqaAPQAQAiEILPSDEHFAqtLERYEGMLVKTtPe-LDMRVTRTFGYdydSRRNNMVLAQ-GRINmQ 365  Vibrio cholerae
WP_013855897  295 EN---NQWLKQGeqeAPQATAiEILSTDENFEhtLERYEGMLVKT-TpeLDMRVTRTFGYdyaSRRNNMVLAQ-GRINmQ 369  Vibrio anguil...
WP_017083792  292 EN---NQWLKQGeqqAPEATAiEALDSDENFAatLERYEGMLVKT-TeaLDMRVTRTFGYdysGRRNNMVLAH-ERINmQ 366  Vibrio splend...
WP_006878363  294 EN---NNWVKQGeqaAPSATDiEILSTDANFDrtLERYEGMLVRT-TeaLDMRVTRTFGYdyaARRNNMVLAQ-GRISmQ 368  Vibrio brasil...
WP_006963247  290 EN---NNWVKQGeqsAPAATAiEVMADDANFDqtLERYEGMLVKT-TeaLDMRVTRTFGYdyaSRRNNMVVAQ-GRINmH 364  Vibrio
WP_020333825  283 NN---VEP--TQi--TITPTPlRTMDTDDSFDftLERHEGMLVEL-DeaADMHITRTFSFdydAYRYNMMASYERVNL-H 353  Vibrio natrie...
WP_019615420  134 KVgpeVKVLSSGh-eLPEARIiRVLEEDENFSvtLERHEGMLVKF-DkeSDMHVTRTYGYdfgPYRDNMVIANARVNQ-H 210  Psychromonas ...
WP_019613126  277 TL---VEGISTGn--SIAATPlRTLETDEDFDftLERHEGMLVAF-DkaADMRITRSFSYdyaGSRNNMVVAN-ERINmH 349  Psychromonas ...
WP_014979146  309 VA---ALDCGTAd--AVAAVE-LSMPYELDL----ETVEGMVVSV----TDATVTSTNNL---WRFGEIVV--SDTIKrQ 369  Alteromonas m...
WP_017095849  367 PTQVFAAE-S--AQ---ATDLAKKNAVSQVYLESDYKAASg-eIPYYPDF-AKDtdq----dgsSEnhIRLGSRVEGLQG 434  Vibrio
WP_001981579  366 PNQQHPAG-S--EQ---ASQQKLDNAQRRLFVESDAKAPDg-qIPYYPTFgRTDvdq----dgsTEdyIRIDDTVSGLEG 434  Vibrio cholerae
WP_013855897  370 PNQLFAAG-S--EQ---AKQQSIENAQRRLFIESDAKAADg-qIPYYPEFgRSDidq----ngsTEdyIRIDDSIIGLEG 438  Vibrio anguil...
WP_017083792  367 PNQLFAAG-S--ED---AKQQTEDNADRRLFVETDQKAGDg-qVPFYPDFgRTDidq----dgsTEdyIRIDDTIVGLEG 435  Vibrio splend...
WP_006878363  369 PNQNFAAG-S--EE---AKQQSIENAERRLYVESDAKAANg-eVPYYPDFgRTDvdq----dgsTEdyIRIDDTIVGLEG 437  Vibrio brasil...
WP_006963247  365 PNQNFAAG-S--DE---AKQQSTENAERRLFVESDAKAANg-tVPYYPDFgRTDadq----ngsTEdyIRIDDTIVGLEG 433  Vibrio
WP_020333825  354 MNQQNVAG-S--VE---AAAKDNENKDRRIYIESFQKAANg-vVPWYSDFlTESavpmedgtttSDdyIRIDDTINGLQG 426  Vibrio natrie...
WP_019615420  211 PNQSNVPG-S--TE---AAAQTQSNKDKRIIVESFAKAPRg-vVPWYPGF-GQDtnq----ngsADnyIRIGDRVDGLEG 278  Psychromonas ...
WP_019613126  350 PNQLNAPAaHegELdsaAEIQTDCNQDKRVVVESFAKAANg-vVPWYPDFgKESaeq----ngsTDdyLRIGDIIDGLEG 424  Psychromonas ...
WP_014979146  370 PSDVAAPL-S--EA---YTAAEEASETSLLTIEDNSSSQYpdaLNYFPTF-SYA----------NA--IRIGDSV-SAAG 429  Alteromonas m...
WP_017095849  435 VVDYSYGQYRLIATNTATKDTFVTKavdaqgntifdVTRKAAPELTNADIRIASFNVLNYF-NSh----sSIGGPlnasc 509  Vibrio
WP_001981579  435 VVSYSYNEYRLIATNTISAENLVHN-----------APRQAKPDMDEGDLRIATFNVLNYF-NS------PFGGDa---- 492  Vibrio cholerae
WP_013855897  439 VLSFGYNEYRLIVTNSLNQENFVRN-----------DPRSEKPDIDEGDLRIATFNVLNYF-NS------PFGGDa---- 496  Vibrio anguil...
WP_017083792  436 VLTYSYGEYRLVTTNQISAENFVRN-----------DPRTDKPDMDEGDLRIATFNVLNYF-NS------PFGGDa---- 493  Vibrio splend...
WP_006878363  438 VITYSYGDYRLIPTNTLTSENFIRN-----------DPRTDDIEMKEGDLRIATFNVLNYF-NS------PFGGDa---- 495  Vibrio brasil...
WP_006963247  434 VLSYSYGDYRLIATNTLTNENFVRN-----------DPRTEGIDMEEGDLRIATFNVLNYFnSPfggdanQHGDN----- 497  Vibrio
WP_020333825  427 VLGYSYSDFRLYVTNEATQDTFIHN-----------NDRTSTPDLVDGDLRVATFNVLNYF-NS------PFGGAe---- 484  Vibrio natrie...
WP_019615420  279 VITYSYNDYRLFVTNEADQDTFVREg----------TDRTEAPVIKEGDISIATFNVLNYF-NS------PFGGPe---- 337  Psychromonas ...
WP_019613126  425 VLTYSYNDYRFYVTNEATKETFVREg----------TDRTAAPVLKEGDLRVATFNVLNYF-NS------PFGGDa---- 483  Psychromonas ...
WP_014979146  430 PLNYSFGTYRINPS------DVIEVt----------SSREVNPVVTEGNLSIATFNVLNYF-NGev---dANGDVt---- 485  Alteromonas m...
WP_017095849  510 sdqadadASRGCNRGAKVNDEFLLQKAKIIKALAAMDSDIIGLMEVENNGFGDGSALKDLTDGLNATIDdvKKHYSYVEi 589  Vibrio
WP_001981579  493 -------NQHGDNRGANNLAEFEVQQAKIVNAIVRLDADIVGLMEIENNGFGEGSAIAQLVNQINSQIAdkKKHYRFVEi 565  Vibrio cholerae
WP_013855897  497 -------NQHGDNRGANNLAEFELQQAKIVNAIVRLDADIVGLMEIENNGFGAGSAIAQLVNQINSQISdkKKHYRFVAi 569  Vibrio anguil...
WP_017083792  494 -------NQHGNNRGANTITEFEMQQEKIVNAILRLDADIIGLMEIENNGFGEGSAIHQLVNQLNDRIErkKDRYTFVAv 566  Vibrio splend...
WP_006878363  496 -------NPHGDNRGANSYEEFEVQQAKIVNAILRLDADIIGLMEIENNGFGDSGAIRQLVDQLNSRIEkkKDRYDIVAi 568  Vibrio brasil...
WP_006963247  498 -------------RGANSFEEFEVQQAKIVNAILRLDADIIGLMEIENNGFGDSGAIRQLVEQLNQRIDkkKDRYDFVAv 564  Vibrio
WP_020333825  485 -------NPYGDNRGAETVDEFERQGDKIAKAIVAMDADIVGLMEIENNGFGEASAVAHLVNKINLLIEdeSDQYSYVS- 556  Vibrio natrie...
WP_019615420  338 -------NPLKQNRGAKSLDEFEVQAAKIVSAMTALDADILGLMEVENNGFGENSAIVNLVSRLNEKLDe-ADHYSISQp 409  Psychromonas ...
WP_019613126  484 -------NPTGQNRGATTAEDFEKQATKIVSAMLAIDADILGLMEIENNGFGDNSAVVDLVKRLNAELDa-ANQYSITEp 555  Psychromonas ...
WP_014979146  486 -------FDYDENRGADDEVAFELQQGRIVEAIVNLNADVVGLMEIENDGFGEDSAIQSLVSAINAELGe-TEQYSFVA- 556  Alteromonas m...
WP_017095849  590 kk---adMTKGEFFGSDAIMVAMLYRADKVVPKGkAKVIVTpeqhvpadvltrtkedgtqesnTALSKY--QRHSLLQTF 664  Vibrio
WP_001981579  566 dsngdgkTDAADSLGTDVITTGVIYRDKVVKLAQn-RVIPMpsqqape--------vidangkVIEDGKnyQRDTLAPTF 636  Vibrio cholerae
WP_013855897  570 dsnndgvTDELDSIGTDVITTGVIYREKVVKLTEn-RVIPMpsqqape--------vlddkgkVIEDGKnyQRDTLAPTF 640  Vibrio anguil...
WP_017083792  567 dsnedgvTDEMDSIGTDVITTGVIYRKKVVKLKD-SRVIAMpsqqape--------vlddsgkVIEDGKnyQRDSLAPTF 637  Vibrio splend...
WP_006878363  569 dsngdkvTDENDYIGTDVITTGVIYRPKVVKLKE-SRVIPMpsqqape--------vlddngkVIEDGKnyQRDSLAPTF 639  Vibrio brasil...
WP_006963247  565 dsngdkvTDENDSIGTDVITTGVIYRSKVAKLKE-VRVIEMpsqqape--------vldddgkVIEDGKnyQRNSLAPTF 635  Vibrio
WP_020333825  557 -------SEDYDYVGTDAITNQVIFKPAKVTLDT-YRLIEMpeqh--------------ategEDTDNY--QRDAITPTF 612  Vibrio natrie...
WP_019615420  410 as---ddLTEEGFIGSDAITSHVIFKASKVSLET-ARVIKMpeqhttr--------tddkgniVAVDSF--MRNAVTPTF 475  Psychromonas ...
WP_019613126  556 q----aeELTEGFIGTDAITTQVIFKASKVGLDT-VRIIEMpeqhapeit----ieiggkdktESGDNY--MRNAITPTF 624  Psychromonas ...
WP_014979146  557 -------TSDGSEIGTDAITVGLLYKATVVTPENdAMVVAMpe------------------qqIDEDSLarMRPSLLQSF 611  Alteromonas m...
WP_017095849  665 TAKGSTVPLSVVVNHLKSKGSHCIeqwqs---feeksDPADLQGKCNRFRTSATKVLGD--SLKSVKGDVLIIGDLNAYG 739  Vibrio
WP_001981579  637 KVKGGNEKITVAVNHFKSKGSACWedaapveqggqagKDLDYQGACENFRVAAAVALGD--ALAKIDGHKVILGDMNSYG 714  Vibrio cholerae
WP_013855897  641 KVKGGNETITVAVNHLKSKGSACWedaapveqggqggKDLDFQGACEQFRVAAAVALGE--ALQKIKGHKVILGDMNSYG 718  Vibrio anguil...
WP_017083792  638 KVKGTKEKLTVAINHFKSKGSKCWedaapveqggqggVDADKQGSCENFRVAAAVALGE--ALDGIKGHKVILGDMNSYG 715  Vibrio splend...
WP_006878363  640 KVKGTKEKITVAINHLKSKGSKCWedaapveqggqggQDLDKQGSCENFRVAAAVALGD--ALNEIDGHKVILGDLNAYG 717  Vibrio brasil...
WP_006963247  636 KIKGTDEKITVAINHFKSKGSKCWedaapvdqggqggVDADQQGSCENFRVAAAVALGD--ALKEIKGHKVILGDLNSYG 713  Vibrio
WP_020333825  613 RINGTDETITVSVNHFKSKGSTCWedvn-----lqnkQDVDGQGSCENFRVSAAQHLGT--ELAKIDGHKLILGDLNSYA 685  Vibrio natrie...
WP_019615420  476 NIVGSDEKLTIAVNHLKSKGSACWenf-------espGDLDKQGSCAAFRVSGAYHLGK--VMATIDGHKMIIGDLNSYA 546  Psychromonas ...
WP_019613126  625 SIAGSDEKLTISVNHFKSKGSACWedyal----qaggDPDK-QGQCENFRVSAAYQLGK--VMAEIEGHKLIVGDLNAYA 697  Psychromonas ...
WP_014979146  612 VHTESSKSFLVAVNHFKSKGSQCAedva-----eapsEITTIQGSCNALRVSAAITLGNalSDESLPERKVILGDLNAYS 686  Alteromonas m...
WP_017095849  740 MEDPVLTLTDYseakydreirtasfttlgkd-dagenkpyeaagsvvtkgfGYINLNTKFHGADtFSYTY-GGEQ-GNLD 816  Vibrio
WP_001981579  715 MEDPMLVLTDYtpekygktiraarntyi------agveqfgdsgaeikhsyGYLNAVAMKHPDS-WSYSF-NDEV-GALD 785  Vibrio cholerae
WP_013855897  719 MEDPMLVLTDYssekygktiraarntyi------agtpqfgddgalithnyGYLNAVAIKHPES-WSYSF-NDEV-GALD 789  Vibrio anguil...
WP_017083792  716 MEDPMLVLTDYseekygkqikaarntyi------dgveqfgdngavitknyGYINAVAQKHPDS-WSYSY-NDEV-GALD 786  Vibrio splend...
WP_006878363  718 MEDPLLVLTDYseekygktikaarntyi------dgqvqfgdegavitdsyGYINAVAKAHPNS-WSYSY-NDEV-GALD 788  Vibrio brasil...
WP_006963247  714 MEDPMLVLTDYseekygkqikaarntfi------gdteqfgdhgavitegyNYINAVAMKHPNS-WSYSY-NDEV-GALD 784  Vibrio
WP_020333825  686 SEDPILLLTELpegysvtpardtfigd---------qkmdgaqpeslsqsfGYRNVIREWHPNS-YSYSY-DDTL-GTLD 753  Vibrio natrie...
WP_019615420  547 NEDPIMVFTNRdnapedyvikaarstyiggtpdaggvqlhgddgavitesyGYANAIKNLHPSS-YSYSY-NDEV-GTLD 623  Psychromonas ...
WP_019613126  698 NEDPIMVLTNRdnapedyvlkaarntsv------ggvelhgddgavitesyGYANVIRDMHPES-HSYSY-NDEV-GTLD 768  Psychromonas ...
WP_014979146  687 AEDPVAVLTDYtpesrgytittavnt-----------gmdegssvdvessfGYHNLAEEFDAEG-FSYWFyGTEQvGSLD 754  Alteromonas m...
WP_017095849  817 HALANPSLANK-VTSITDWHINASESTMFEYSSKYTGkm------pKyADVFSASDHDPVIIALDY 875  Vibrio
WP_001981579  786 HLLVSPSLKHK-VVDATDWHINGAESTLFDYNDEFKGnl------pKyKDQFRASDHDPAVLELNI 844  Vibrio cholerae
WP_013855897  790 HLLVSKSLKGK-VVDATDWHINGGESTLFDYNSEFKGdl------pKyQDHFRASDHDPAVLELNI 848  Vibrio anguillarum
WP_017083792  787 HLLISDSLKDR-VVDATDWHINGGESTLFDYNEEFKGdl------pKyQDHFRSSDHDPAVLELRV 845  Vibrio splendidus
WP_006878363  789 HLLMSPSLEKH-FVDATDWHINGGESKLFDYNEEYKGdl------pKyNDHFRSSDHDPAVLELNM 847  Vibrio brasiliensis
WP_006963247  785 HLLISPSLKKH-FVDATDWHINGGESTLFDYNDEYKGdl------pKyNDHFRSSDHDPAVLELNM 843  Vibrio
WP_020333825  754 YILADAETAENnVVAAIDWNINSPESTYVDYTTEYSGdl------pKySDIYRASDHDPAIVVLAF 813  Vibrio natriegens
WP_019615420  624 YILVSPSLNSM-VVDGIDWNINAPESTLFEYPTKNSGdf------sKyNDAYRSSDHDPAIVVLNF 682  Psychromonas ossibalaenae
WP_019613126  769 YILASASLKDK-IVDSMDWNINSSETTLFEYPSKYTGdl------pKyDDAYSSSDHDPAIVILNF 827  Psychromonas ossibalaenae
WP_014979146  755 HVLASEAMLAD-AIDGAHWNINSVEAYQLQYDQALRYypdedgyafTdVGPFRSSDHDPFIATFDL 819  Alteromonas macleodii
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