Conserved Protein Domain Family
SLATT_6

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NF033630: SLATT_6 
SLATT domain
The SLATT domain contains two transmembrane helices. SLATT domains are generally predicted to function as pore-forming effectors in a class of conflict systems which are reliant on the production of second messenger nucleotide or nucleotide derivatives. SLATT domains are predicted to initiate cell suicide responses upon their activation. This SLATT family associates with a SMODS nucleotide synthetase domain fused to the predicted AGS-C sensor domain. It is sometimes further coupled to R-M systems.
Statistics
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PSSM-Id: 468116
Aligned: 52 rows
Threshold Bit Score: -1
Created: 24-Apr-2023
Updated: 3-May-2023
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_041080731   1 MNK-NSLLKSIAIKGYDVGFGAKKHFATFDLVSKLPNSIALTTLTIGVIqlaFPIPDLANRIISVGLIFIGIVALLIHKY 79  Staphylococcus
WP_033008180   1 MTE-QSIKKQIAREYYNVIYGAKLNFSSFDFCEKIPSLISFFSLSLGILg--LAFAEFNSKTLAASLLIVGLVGLLLKPR 77  Vibrio harveyi
WP_009600069   1 MSE-QTTKKQIAREYYNVIYGAKLNLASLDICEKLPSIISLLSLSLGILg--LSFETFNNKSLASFLLIAGLIGLMLKPR 77  Vibrio caribbea...
WP_031823314   1 MTV-QTAKKQVTREYYNVLYSAKLHLASFDICEKLPTAISFISLSFGVLg--LAFAEFNSNALASLLLIIGIIGIALKPR 77  Vibrio parahaem...
WP_011081596   1 MTE-QTIKKQVAREYYNVLYSAKLHFASFDICEKLPTIISVVSLSFGVLg--LAFAEFNSKALAALLLIIGIIGIVLKPR 77  Vibrio vulnificus
WP_005299114   1 MTE-QTIKKQVAREYYNVLYSAKLHFASFDICEKLPTMISVISLSFGVLg--LAFAEFNSKALAALLLIIGIIGITLKPR 77  Photobacterium ...
WP_014980302   1 MNE-QKIKTQIAREYYNVIYGAKLHFASFDLCEKLPTFISVISLTFGVLg--LAFSEFNSQSLGAILLIIGIIGISLKPR 77  Alteromonas mac...
WP_029845909   1 MNEkERLKKDIADTAYNIIYGAKLNFSSYELSKNISTGVSAFSLAIGIIa--LAFVEFATKELSVALLLLGLLGLLVGKS 78  Vibrio parahaem...
KJD21721       1 MIK-EDLLRQIAENAYNIGFGAKKSFATFDIIDKIPNMLNFCSLAIGILa--LFIDELNIKIVSASLIIFGIIGIYISKY 77 
WP_021084438   1 MTK-EVLLKRIAESAYNVGFGAKKHFATYDITSKVPGIIEFLSLSIGVLa--LCFDVVSTKIVSTCLIIFGIVSIYISKY 77  Campylobacter c...
WP_041080731  80 LRDKEEYKEAGIEINKIYQGLRDLYFKVKgTDENSTDEMKELekEYKSLIESFYNTGITDQIMFSDWYAHYKFFvqL--E 157 Staphylococcus
WP_033008180  78 EAIKEQYYTAGVELTQLSKKLEIIHSEVD-ENDLTSVESARK--SLIQTQELHKEIKQPSPVLLATWFAHYKLF--SehN 152 Vibrio harveyi
WP_009600069  78 EIQKDKYCKAGGELTDISKRLELLHSEIE-PSEPESEASGRV--ELRKLQTEHKEVYQPSPVFLASWYAHYKLF--SehN 152 Vibrio caribbea...
WP_031823314  78 ELQKDHYKAIGTSLTDISKKLEDIYCQID-EQDVTSVAKART--DLRQIQQEHSSIVALPPVLLSSWYAHYKVF--SehN 152 Vibrio parahaem...
WP_011081596  78 ELQKEQYEATGISLTDISKKLERIYCEVD-IQDTNSVAKARA--DLAQVQADHRAVDTMSPVLLSSWYAHYKVF--SehN 152 Vibrio vulnificus
WP_005299114  78 ELQKGQYEATGVSLTDISKKLEHIYCEID-VQDTESVAKARA--DLAQAQADHRAVGTMPPVLMSSWYAHYKVF--SehN 152 Photobacterium ...
WP_014980302  78 ELQKDEYKATGDKLNQVGKRLENLYCEIE-EKDKDSVAKARA--ELSQLQKEHHDIGTMAPVLLSSWYAHYKLF--SehN 152 Alteromonas mac...
WP_029845909  79 PDSMVNLKNGAIKLTQYHDQLKILYSEVD-SS--STTEDIQL--RLEEIQNEARDFYSTDQLPFASWFAHHKLF--NehQ 151 Vibrio parahaem...
KJD21721      78 YDKKNIYKTSGSKITKLFNELKSLYHSVKaKPNNANFDKDIS--KMKEIEDEFYSIAISNQILFSDWYAHYKFFwqWttH 155
WP_021084438  78 NESQVEYSKVASELTQIFNNMKDLYCDVKsKEHTENLDTDIS--KLKELEERLYLISRSKQIILSDWFAHYKFFwqWrtH 155 Campylobacter c...
WP_041080731 158 TDWIEEQRRFT-RKDKIPLSLVSLIA 182 Staphylococcus
WP_033008180 153 SKWLCNELDLT-WRDKFPLSLRVAIV 177 Vibrio harveyi
WP_009600069 153 NKWFCIELGLT-WKDKIPLSLRSTVL 177 Vibrio caribbeanicus
WP_031823314 153 SDWMCAELNLG-WKDKVPLSLRMTVI 177 Vibrio parahaemolyticus
WP_011081596 153 SDWMSTELALG-FNDKVPLSLRAVVI 177 Vibrio vulnificus
WP_005299114 153 SDWMSKELELG-FNDKVPLSLRAVII 177 Photobacterium damselae
WP_014980302 153 SDWMCRELELG-FFDKVPLSLRITII 177 Alteromonas macleodii
WP_029845909 152 SEWLCNALNLTfWKDKLPSTLKLLIK 177 Vibrio parahaemolyticus
KJD21721     156 IKWLEDELKLTfWKNKIPLSFVVFVG 181
WP_021084438 156 IKWLVDELGLT-IKDKIPLSFVAICT 180 Campylobacter concisus
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