Conserved Protein Domain Family
act_recrut_TARP
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NF033567: act_recrut_TARP 
type III secretion system actin-recruiting effector Tarp
The founding member of the Tarp (translocated actin-recruiting phosphoprotein) is CT456 from Chlamydia trachomatis. Tarp is a type III secretion system effector. Orthologs are found other Chlamydia, but are highly variable in length because many lack much of the repeat region.
Links
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Statistics
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PSSM-Id: 411196
Aligned: 6 rows
Threshold Bit Score: 637.791
Created: 19-Oct-2021
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_011458384   1 MTFPINNPVTTNVTTTTSTTPVVTTSTSFGGHVVSTTGTGNVETTAQTVSTAADQAVSQaeADPG-AVIFTTERNVSSTT 79  Chlamydia felis
WP_014541164   1 MTNSISGYQPTVTTSTSSTTSASGASGSLGASSVSTTANATVTQTANATNSAATSSIQT--TGET-VVNYTNSASAPTVT 77  Chlamydia trach...
WP_014541791   1 MTNSISGYQPTVTTSTSSTTSASGASGSLGASSVSTTANATVTQTANATNSAATSSIQT--TGET-VVNYTNSASAPTVT 77  Chlamydia trach...
WP_010883210   1 MAAPINQPSTTTQITQTGQTTTTTTVGSLGEHSVTTTGSGAAAQTSQTVTLIADHEMQEiaSQDGsAVSFSAEHSFSTLP 80  Chlamydia pneum...
WP_011006142   1 MTSPINNPSTTNVTTTTTSTPVVTTSTSFGGHVVSTTGTGALETTAQTVNTTAEQAVAQaeSDSG-AVIFTTQRDVSTTA 79  Chlamydia caviae
WP_014944769   1 MSSPINNQSITNVSTTTTSTPVVTTSTTFGGHVVSTKGTEAAETTSQTVNTAAEQAVSQaeSDSG-AVVFTTERSVSTTS 79  Chlamydia psittaci

WP_011458384  80 PSTGGAAATATAANLVGSRILGIGRGRTESTSSSDSSISDTSSSSSLQGA-----GGATGGT------------------ 136 Chlamydia felis
WP_014541164  78 VSTSSSSTQATATSNKTSQAVAGKITSPDTSESSETSSTSSSDHIPSDYDdvgsnSGDISNNyddvgsnngdissnydda 157 Chlamydia trach...
WP_014541791  78 VSTSSSSTQATATSNKTSQAVAGKITSPDTSESSETSSTSSSDHIPSDYDdvgsnSGDISNNyddvgsnngdissnydda 157 Chlamydia trach...
WP_010883210  81 PETGSVGATAQSAQSAGLFSLSGRTQRRDSEISSSSDG-SSISRTSSNAS-----SGETSRA------------------ 136 Chlamydia pneum...
WP_011006142  80 PTTGGSASTATAASLLGTHILGTGRARTDSTSSSDSSI-SDTSTTSSTQD-----TGATGETqdagatgetqd------- 146 Chlamydia caviae
WP_014944769  80 PSTGSVGTTATAANLLGSQILGLGRPRSDSTSSSDSDALSDISSTPSSQN-----SGDTSSIedl--------------- 139 Chlamydia psittaci

WP_011458384     --------------------------------------------------------------------------------     Chlamydia felis
WP_014541164 158 aadyepirtteniyesiggsrtsgpentsggaaaalnslrgssysnyddaaadyepirtteniyesiggsrtsgpentsg 237 Chlamydia trach...
WP_014541791 158 aady---------------------------------------------------------------------------- 161 Chlamydia trach...
WP_010883210     --------------------------------------------------------------------------------     Chlamydia pneum...
WP_011006142     --------------------------------------------------------------------------------     Chlamydia caviae
WP_014944769     --------------------------------------------------------------------------------     Chlamydia psittaci

WP_011458384 137 ----------------------------------------------QEASSDVDLGDLAGLRGSE-----ATEGAARPdG 165 Chlamydia felis
WP_014541164 238 gaaaaalnslrgssysnyddaaadyepirtteniyesiggsrtsgpENTSDGAAAAALNSLRGSSyttgpRNEGVFGP-G 316 Chlamydia trach...
WP_014541791 162 -------------------------epirtteniyesiggsrtsgpENTSDGAAAAALNSLRGSSyttgpRNEGVFGP-G 215 Chlamydia trach...
WP_010883210 137 -------------------------------------------------ESSPDLGDLDSLSGSE-----RAEGAEGPeG 162 Chlamydia pneum...
WP_011006142 147 ------------------------------------agatgeaggtQEASGDVDLGDLAGLRGSE-----AADGAERAeG 185 Chlamydia caviae
WP_014944769 140 ----------------------------------------------asASGDMDLGDLEGLRGTE-----AADGAARPdG 168 Chlamydia psittaci

WP_011458384 166 PGGLPSMALPKYDPTNKASIIKFLSTPSVQAKLQTKAGHIVFMDEARGSFIFVRNGDWNTAESIAVTNGKTKEPItDIKD 245 Chlamydia felis
WP_014541164 317 PEGLPDMSLPSYDPTNKTSLLTFLSNPHVKSKMLENSGHFVFIDTDRSSFILVPNGNWDQVCSIKVQNGKTKEDL-DIKD 395 Chlamydia trach...
WP_014541791 216 PEGLPDMSLPSYDPTNKTSLLTFLSNPHVKSKMLENSGHFVFIDTDRSSFILVPNGNWDQVCSIKVQNGKTKEDL-DIKD 294 Chlamydia trach...
WP_010883210 163 PGGLPESTIPHYDPTDKASILNFLKNPAVQQKMQTKGGHFVYVDEARSSFIFVRNGDWSTAESIKVSNAKTKENItKPAD 242 Chlamydia pneum...
WP_011006142 186 PGGLPSMALPKYDPTDKASIIKFLSTPSVQAKLQTKAGHIVFMDEARGSFIFVRNGDWSTAESIAVTNGKTKEPItDVKD 265 Chlamydia caviae
WP_014944769 169 PGGLPSMALPKYDPTNKASIIRFLSTPSVQAKLQTKAGHIVYMDEARGSFIFVRNGDWNTAESIAVTNGKTKEPItDVKD 248 Chlamydia psittaci

WP_011458384 246 LEMCIAKFCVGFESMHADWENNIQPRIAGQTGEQ--GTY-NHLLMSMKFKTTVLYGPWNSKESSGNYTPSVWRRGTKCDS 322 Chlamydia felis
WP_014541164 396 LENMCAKFCTGFSKFSGDWDSLVEPMVSAKAGVAsgGNLpNTVIINNKFKTCVAYGPWNSQEASSGYTPSAWRRGHRVDF 475 Chlamydia trach...
WP_014541791 295 LENMCAKFCTGFSKFSGDWDSLVEPMVSAKAGVAsgGNLpNTVIINNKFKTCVAYGPWNSQEASSGYTPSAWRRGHRVDF 374 Chlamydia trach...
WP_010883210 243 LEMCIAKFCVGYETIHSDWTGRVKPTMEERSGAT--GNY-NHLMLSMKFKTAVVYGPWNAKESSSGYTPSAWRRGAKVET 319 Chlamydia pneum...
WP_011006142 266 LEMCIAKFCVGYESMQADWSNNIQPRVAGQTGET--GHY-DHLLMSMKFKTTVLYGPWNSKESSSGYTPSVWRRGTKCDS 342 Chlamydia caviae
WP_014944769 249 LEMCIAKFCVGYETMQADWTNNIQPRIAGQTGET--GHY-DHLLMSMKFKTTVLYGPWNAKESSSNYTPSVWRRGTKCDS 325 Chlamydia psittaci

WP_011458384 323 GPIWGDVGGLKGINWNNFQK---PEESTAFSRETA-------SATQPQTGPYTP---PVI--NVNLGGISTNVNVT--GG 385 Chlamydia felis
WP_014541164 476 GGIFEKANDFNKINWGTQAGpssEDDGISFSNETPga----gPAAAPSPTPSSI---PIInvNVNVGGTNVNIGDTnvNT 548 Chlamydia trach...
WP_014541791 375 GGIFEKPNDFNKINWGTQAGpssEDDGISFSNETPgagpgagPAAAPSPTPSSI---PIInvNVNVGGTNVNIGDTnvNT 451 Chlamydia trach...
WP_010883210 320 GPIWDDVGGLKGINWKTT-----PAPDFSFINETPggg-ahsTSHTGPGTPVGAtvvPNV--NVNLGGIKVDLGGInlGG 391 Chlamydia pneum...
WP_011006142 343 GPIWGDVGGLKGINWNNVAK---P-DATAFSRETAa-----pA--QPQPGPYTP---PVI--NVNLGGISTNVNVT--GG 404 Chlamydia caviae
WP_014944769 326 GAIWGDVGGLKGINWNNVQR---PNEGTLFSRETPs-----pTQQQPQPIPYAQ---PVI--NVNLGGISTSVNVT--GG 390 Chlamydia psittaci

WP_011458384 386 TTTTTVSSTSSQPTDTSG--------GRVSHDQSTDTSEFDEVGTPGEDQQEvydfdevdslsttslkhEDeLFFESEGE 457 Chlamydia felis
WP_014541164 549 TNTTPTTQSTDASTDTSDi-------DDINTNNQTDDINTTDKDSDGAGGVN-----------------GD-ISETESSS 603 Chlamydia trach...
WP_014541791 452 TNTTPTTQSTDASTDTSDi-------DDINTNNQTDDINTTDKDSDGAGGVN-----------------GD-ISETESSS 506 Chlamydia trach...
WP_010883210 392 ITTNVTTEEGGGTNITST--------KSTSTDDKVSITS-----TGSQSTIE-----------------EDtIQFDDPGQ 441 Chlamydia pneum...
WP_011006142 405 TTTTTVTTSPTPDMSEVDstagfdeiDGLSTQDESTETDIDDVETQSTSTQY-----------------EDtLHYESGGE 467 Chlamydia caviae
WP_014944769 391 TTTTTVNSTTTQPTDTSG--------NGVDNDQNVDDANLDDVETESTGTQE-----------------DPsIHFFDEGN 445 Chlamydia psittaci

WP_011458384 458 GEPSLDPLPPGPPAAPqeAPPPPaappaaaqggvnisgmpvdTLKDILANARQHLDTVYD-QNGAHHEGnqdlgtvirts 536 Chlamydia felis
WP_014541164 604 GDDSGSVSSSESDKNAsvGNDGP-------------------AMKDILSAVRKHLDVVYPgENGGSTEG----------- 653 Chlamydia trach...
WP_014541791 507 GDDSGSVSSSESDKNAsvGNDGP-------------------AMKDILSAVRKHLDVVYPgENGGSTEGplpanqtlgdv 567 Chlamydia trach...
WP_010883210 442 GEDDNAIPGTNTPPPP--GPPPNlsssrl-------ltisnaSLNQVLQNVRQHLNTAYD-SNGNSVSDlnqdlgqvvkn 511 Chlamydia pneum...
WP_011006142 468 EVDNLAPA----PLPP--GPPPPakggvni------tgmpaaNLQQILNNVREHLDTVYD-QNGVHHEGnqdlgtvvrts 534 Chlamydia caviae
WP_014944769 446 GIDSLEPA------PP--GPPPPtqgsvni------tgmpkeSLQQVLQNVRQHLDTVYD-QNGEHHQGsqdlgtvvrts 510 Chlamydia psittaci

WP_011458384 537 engtyqptillnkhqadggtsvqg-----------------------------------------------------ggg 563 Chlamydia felis
WP_014541164     --------------------------------------------------------------------------------     Chlamydia trach...
WP_014541791 568 isdvenkgsaqdtklsgntgagdddptttaavgngaeeitlsdtdsgigddvsdtasssgdesggvsspssesnkntavg 647 Chlamydia trach...
WP_010883210 512 sen----------------------------------------------------------------------------- 514 Chlamydia pneum...
WP_011006142 535 engtykptvllkndqgdggrgv--------------------------------------------------------qr 558 Chlamydia caviae
WP_014944769 511 engtykptvllnnnqggggggvq------------------------------------------------------rre 536 Chlamydia psittaci

WP_011458384 564 ldndegselgnilshvrqhldvvypaggggeAISANQNLGDVIRDVQSgntpKPTQPEGVFTARRVdiggdeDTTTQGAQ 643 Chlamydia felis
WP_014541164 654 -------------------------------PLQANQTLGDIVQDMET----TGTSQETVVSPWKG------STSSTESA 692 Chlamydia trach...
WP_014541791 648 ndgpsgldilaavrkhldkvypgdnggstegPLQANQTLGDIVQDMET----TGTSQETVVSPWKG------STSSTESA 717 Chlamydia trach...
WP_010883210 515 ----------------------------------------------------------gvnfptvilpkttgDTDPSGQA 536 Chlamydia pneum...
WP_011006142 559 sndddggelgnilnrvrehldvvypesnegePIPVNQNLGDVIQAVESgntpKPTQPEGVFVAKKV------NLDGDGNI 632 Chlamydia caviae
WP_014944769 537 sndnedgelgnilgrvrehldvvypegskgeAIVVNQNLGEVIRDVEAgntpKPTQPEGIFFAKRV------NVDENGKI 610 Chlamydia psittaci

WP_011458384 644 GGEGTffaqrvnldengnivgnsRTEPGSRASRLMG---------ASSGEGP----GELEHLLQKLRAHLDNSFDQQGNL 710 Chlamydia felis
WP_014541164 693 GGSGSvqtllpspp-ptpstttlRTGTGATTTSLMMggpikadiiTTGGGGRipggGTLEKLLPRIRAHLDISFDAQGDL 771 Chlamydia trach...
WP_014541791 718 GGSGSvqtllpspp-ptpstttlRTGTGATTTSLMMggpikadiiTTGGGGRipggGTLEKLLPRIRAHLDISFDAQGDL 796 Chlamydia trach...
WP_010883210 537 TGG------------------------------------------VTEGGG---------HIRNIIQRNTQSTGQSEGAT 565 Chlamydia pneum...
WP_011006142 633 VGGNA------------------RTSSESRASNLMS---------AAGGEGA----EGLEHLLPQLRSHLDDAFDQQGNL 681 Chlamydia caviae
WP_014944769 611 VGNNS------------------RTETRSRTNNLMG---------ATSGDGP----GGLEHLLPQLRAHLDESFDPQGNL 659 Chlamydia psittaci

WP_011458384 711 ITPQNTNVGRLIKAFQERTGSGGIVGPAPmqatviassptiqql-pstetlqqpqtaetiSSNAAPDLYAAAGNVADSLS 789 Chlamydia felis
WP_014541164 772 VSTEEPQLGSIVNKFRQETGSRGILAFVE-------------------------------SAPGKPGSAQVLTGTGGDKG 820 Chlamydia trach...
WP_014541791 797 VSTEEPQLGSIVNKFRQETGSRGILAFVE-------------------------------SAPGKPGSAQVLTGTGGDKG 845 Chlamydia trach...
WP_010883210 566 PTPQ-PTIAKIVTSLRKANVSSSSVLPQPqvattitpqartaststtsigtgteststtsTGTGTGSVSTQSTGVGTPTT 644 Chlamydia pneum...
WP_011006142 682 VGAPGTNVGSLIKAFQERTGSGGIVAPLPasvvtsssapqqsa---tvsdlpkaqtaettTPGGSPDLHGAAKGVADSLS 758 Chlamydia caviae
WP_014944769 660 ITPQKTNVGNLIKAFQERTGSGGIVAPVPaqatvitsrpvqqqs-aiisvlpqaqtaetaAPLEAPDLHGAARDVASSLS 738 Chlamydia psittaci

WP_011458384 790 NLLQAATPpvgqtvtspaitqgtatsmpvag-srqtattltgespsgipqaaanVTQTLSNVTQKLLLFEKGRR-LQEAL 867 Chlamydia felis
WP_014541164 821 NLFQAAAA----------------------------------------------VTQALGNVAGKVNLAIQGQK-LSSLV 853 Chlamydia trach...
WP_014541791 846 NLFQAAAA----------------------------------------------VTQALGNVAGKVNLAIQGQK-LSSLV 878 Chlamydia trach...
WP_010883210 645 TTRSTGTSattttssastqtp---------------------qaplpsgtrhvaTISLVRNAAGRSIVLQQGGRsQSFPI 703 Chlamydia pneum...
WP_011006142 759 NLLQAATPsttsttvsspaprqetatstsvagtrgtatpttggspsgipgaaanVTATLSSVANKIALFEKGAR-LQEAL 837 Chlamydia caviae
WP_014944769 739 NLLETATLsagrqvsspapqqqvasstpvtg-srqtatltrgeapsgipeaagnVTQALGNVAKKLQMFEQGSRlLQEAL 817 Chlamydia psittaci

WP_011458384 868 NSADTPTQ--GQKLFDAAKQTTAQLSKMIYRAT 898 Chlamydia felis
WP_014541164 854 NDDGKGSV--GRDLFQAAAQTTQVLSALIDTVG 884 Chlamydia trachomatis
WP_014541791 879 NDDGKGSV--GRDLFQAAAQTTQVLSALIDTVG 909 Chlamydia trachomatis
WP_010883210 704 PPSGTGTQnmGAQLWAAASQVASTLGQVVNQAA 736 Chlamydia pneumoniae
WP_011006142 838 DSADTESTq-GKQLLEAARNTTTMLSKTLSKVT 869 Chlamydia caviae
WP_014944769 818 DSADTESTq-GKQLADAARNLTTQLSKTLSKAT 849 Chlamydia psittaci
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