WP_026654576 23 RYPVRFLFMELNNNTQDEIMDLVkSGNgELLELSDYVMQKDDGWLTKSRFMQVINTNVSKN--KDTYVVGFSEMIRFYSR 100 Butyrivibrio... WP_076004839 20 DKTPFFLFVSDGQYASAIAELSVlGLD---FVQMSSFCSGNDKLPDIDGLLSYIEAIDVNTkgNKFVVTGFGEYLALRGN 96 Dehalogenimo... WP_092467483 14 VKLPYFLIVGDRQYKDIKNKLSElGLA---SVKVSDYC-GDDKFPDIDGLFERLKTADVNAgdNKLVVIGLGEYLALRGN 89 Desulfallas ... WP_062282325 14 VSTPFFYSVSDRNYLSVREKLTEsGFS---IVKVSDYCQNDDKLPDIDGLINDLRTLDSTFvgKKVALIGLGEYLTLRGR 90 Flexilinea f... 3_ncbifamImport 1 TYYPFFITVGDENYCDIKNKLSNlGLH---FIKLSDYCKEDDKLPDLDALYEQLKTTNKMLgvNTIAILGLGEYLALCGK 77 WP_087307207 14 LHKPFFMVVGDKEYGEIINCLKSrAIS---IICVSDCCRSEDKVPDMDVLRQKLETADVSCdyNDVVLLGLGEYLALSGE 90 Lachnoclostr... CDC79182 14 KGLPFFYVIGDEDYCSVLEELKQaDIS---VVRMSEFCLKDDKFPSVDELVDYFRTSDVDYrdNKFVVIGLGEYLALRGS 90 Clostridium ... WP_037355505 22 TGFPLIIDTEDYDSFHDLIFRLRiDVA-KKFIYVSDFCKEGA-IPNIEQAYSSAFAd------GVHVLVGLSQACMLQSQ 93 Selenomonas ... SEG30118 22 TGRALLVNTENYTVYQNVKAKLEaDGN-KNCVYVSKCCPEND-LPNMDDILGKVTGs------QDYVLVGYSQAAMLRGL 93 Eubacterium ... WP_055062750 18 KRYPLIVDVQTREDLANIAEYFKvGS--NKFPAIEEFCNQDE-AIKLDELYASVSSNs-----GNTFITGLSGFLMLFGE 89 Lachnospiraceae
WP_026654576 101 keiestvvslfDIENSDIMDSEEDAARRIYFICFSMMDDVYrVLQNcfsriNLINPFINSDyELSGkYRQICFVSDDYad 180 Butyrivibrio... WP_076004839 97 n----------EAKRALSRLKDLNITRVKVVLLLRGLASQIvGLQTdp--rFDNRRYCVID-KAECnLSFTLAAPS---- 159 Dehalogenimo... WP_092467483 90 t----------EAASVFSQLKDLNIGGAKVVLLLRGVATQInSLQVdp--rFDSRRFSIID-KADCdLSFTLAPPS---- 152 Desulfallas ... WP_062282325 91 r----------EAASVLSQLKDLNLGTIKVVLLLCGIETQVkDLQSdp--rFDRRRCCLSD-ETDCnLSITLVSPA---- 153 Flexilinea f... 3_ncbifamImport 78 s----------EVNRVLTHLQAMNTSKTKVVLLLRGVSSYVnNLCSdi--rFDSSRFFCAG-STDCnLSITVSKLS---- 140 WP_087307207 91 t----------RTKDILSELVNYNLGSAQVVLLLRCVSTQVkELVKsdkrlLESGRVVFGD-DLGTaVSFKFSAPG---- 155 Lachnoclostr... CDC79182 91 a----------VADKELRRLRNTTLGNARAILLLRGVSSQAaKIIRddnkmVEQQRAYISN-NLLTnVSVTNMPED---- 155 Clostridium ... WP_037355505 94 s----------TLQEYLDRAVNETCREHTIILLMHCREYLQkKCRQdv--rLERRIRFLGN-KNQPlPQIIIERNPRYar 160 Selenomonas ... SEG30118 94 s----------YLEQMIRTLLEVPVSGHTIVLLDHCEQYVKkAFSIhp--dIPKRVILVEG-DVSVlPKIRLAVSIEEcv 160 Eubacterium ... WP_055062750 90 n----------VAKQALKTLITTSISGHVVIITYQCEKYLR-FTDPri--sESGRLVIVDG-NPDNiCNINFISPTLSdi 155 Lachnospiraceae
WP_026654576 181 -nIKYNKISKSVDWIGLWKNsqilDFSRPIWCCSASLFEWHKKASPDNAFQIDVVENTKQYLQKILDFEIGFDYKESEAI 259 Butyrivibrio... WP_076004839 160 --VGLSALSGFKVMLADLEN----GRCGNVVVNTAVDLDE------AMFTVHRISSAYEGVKFSTICFA--LPRSCGSDT 225 Dehalogenimo... WP_092467483 153 --VGLPALTGIKALLITLEN----GISGNVVVNTTVNLDN------ALLTVHKITDAYDGIKFISLGFN--LPRSCGSDV 218 Desulfallas ... WP_062282325 154 --VDITATMGFKALLMKLEN----DKTGNIAVKTVVNLND------AIATLHKISNSYEGIRLTCPKFD--LPYSCGNEQ 219 Flexilinea f... 3_ncbifamImport 141 --TSYGVLKGFKALLNELEN----GKRENIIVNTNIDLSQ------SLFTKRERSNAYDEILFILENFS--LAETCGTNE 206 WP_087307207 156 --LGIYELNGIKNVLKTLET----GVSGAIFASTVIEFKD------SILPVQRVRDSYEAISRKLNMCA--IPKECGIEE 221 Lachnoclostr... CDC79182 156 --GGLVVQTGIKYLLRAFED----GAIGNVYTSTSLVLDN------ALFPLFTLSGAYSVVKYIVGDFE--LDSGLGTEE 221 Clostridium ... WP_037355505 161 -gKTYNSIGELLSALEQMTN----ESIKDSLMISLVTKYSPTLFNKAVYSVSQGPESFDVLCQRFPVFSSGFAKENGTEE 235 Selenomonas ... SEG30118 161 gyNPLSSMKRLLAYFEGITD----EIIRRNPEVAVVTKYSPELFRNALISVSACDDIYSGICKIYPEISAGTEYRFGTDE 236 Eubacterium ... WP_055062750 156 ftDSYSGIQNIG---TAIDS----CFNRDAYIATAIDKSS---FAESVFHISQVNNSYDILRNKDSRTG-IVPQACGLPE 224 Lachnospiraceae
WP_026654576 260 YWNRLLEDIDNIAisKSLGEAISFALGVDVTkiEALAGKLFISDSnyEKWLIRNYVLVYAEES---FLSRVIKYSIQGSV 336 Butyrivibrio... WP_076004839 226 RWTELLTELNKSNgsLDEVFEKHGLGGNLESdfYARVSGNDYCN-----WLYFICLKCKADTLpngYLRFVLERTRRFED 300 Dehalogenimo... WP_092467483 219 QWAKLLTELVQNKgsLDAAFEKNGFGGTLEAdfYVRVAGLEYRN-----WLYFIALKSKSDTLsngYLRFVLDNTNRFED 293 Desulfallas ... WP_062282325 220 QWTRLLSEINQNNgsFEKIFKKYGFTNDLNIdfYNLVAGLDFRN-----WLYFIFLKIRINVSgsgYLNYVLEITSQFDK 294 Flexilinea f... 3_ncbifamImport 207 YWSELLKVLTANDnsLEAVLEKYGLTVDLELniHDKIFGREYRN-----WLFFIALKINIDRLsnsYLRLVLENTHDYKN 281 WP_087307207 222 MWRKLLSELRDKEfrINEIFSDYGFLEYQDAelYEFLYEEEYRS-----WLFYIYLRVNEKLYdgkYLGYVLGKSIGIES 296 Lachnoclostr... CDC79182 222 QWKRLLKDLNKCSkdIRAVFDKYGIDERLIDdlRSAVSGLEYRN-----WLVFLYLKLNAKQIqnyYLKLVIDETLNFED 296 Clostridium ... WP_037355505 236 QWQWLLERLEKEs-fEKIIAEEFKVFD-LEMcvGDVLENNDSNSN--LLWLYWLAIR-IQG-SnnsYLNKAVKDIKNQLE 309 Selenomonas ... SEG30118 237 QWMYLKERIAECGtlSSTAKNMFGSTDNLAShiGEVVEEGESNK----LWFLWLCMK-IFNNPfnkYLYRVMQNSVNVND 311 Eubacterium ... WP_055062750 225 QWDYVLHQMGKSGtwTTVIVDNFGSENNLLHviREYPKFDVEKR-----WLYYIALL-ICGVKnndYLKLALNKTSKSSE 298 Lachnospiraceae
WP_026654576 337 K-DFLLNVWLQGYKISNLSMLEERLriiteinkyansyipEESIQEEIVNDLSRVISVPIsngANKYGVnfieigksngl 415 Butyrivibrio... WP_076004839 301 FvGNVLNTIIEIKHSDTRFVAFYRE---------------RKMLVEKFPES--DIADFVV---NNRKVE----------- 349 Dehalogenimo... WP_092467483 294 FkTNVLNAIIEVPHIDKRFRMFYAE---------------RKLLVEKFPES--DIADFVV---NNRKNI----------- 342 Desulfallas ... WP_062282325 295 FkDNVLNAIIEINHTDNRFHSFYLE---------------RKALVDNFPES--EIANFVI---NNRKNI----------- 343 Flexilinea f... 3_ncbifamImport 282 LkLNLLNYIINISHTDKKHNTLYLE---------------RKDLIRDFPEP--DIAEFII---RNRKNL----------- 330 WP_087307207 297 FkYNVKNAIIDIPHEAPTFPTFYKE---------------RKKLLSNYPEP--EMASFVS---KNRVNE----------- 345 Lachnoclostr... CDC79182 297 FkTNLMVKITEFSHQDRYFRLLYDE---------------RKKLLRNFPEE--DIAVFVK---TNEIDP----------- 345 Clostridium ... WP_037355505 310 LeKTIYFSILSVDVNEKNFQQYYRE---------------RKKLLDKLKDNKRIAVQFCN---EIGQKG----------- 360 Selenomonas ... SEG30118 312 FeEHAYLDILSIDHNDSIFRQCYIE---------------RKRLLDMLSENVMLTDLFCS---KIGIYQ----------- 362 Eubacterium ... WP_055062750 299 LiKNIFRSVLDIDWKSENYQKLYRQ---------------RKSLISELKKPLPETIDFCK---ILSTKG----------- 349 Lachnospiraceae
WP_026654576 416 aeeemkirvgeyfsRIFKPAYTGLSYAEKEFLINLHAy------gFLDRGDMQIMYPSYYSYLYGVGDNlv--------- 480 Butyrivibrio... WP_076004839 350 --------------SESIYKLTDSTKSEREEIIAWLSq-------nGMITQIESIYPALAAYLKRYVFKcp--------- 399 Dehalogenimo... WP_092467483 343 --------------AESVYKLTDGTKTEREEVIAWVSq-------nGVIPQIADIYPALTAYLKKYVFNcg--------- 392 Desulfallas ... WP_062282325 344 --------------NESIYKLTDNTRTEREEIISWVVk-------nGIPSCLTLVYPALSSYLERYEFKcd--------- 393 Flexilinea f... 3_ncbifamImport 331 --------------SESIYKLTDNTIVEREEIIAWVSq-------nGIIEEIAEIYPVLNTYLKKFVFNcg--------- 380 WP_087307207 346 --------------KESVYKLTDNTLVERQEIIIWIAc-------hGIPDNLAVIYPDLALYMKKYSFSgknl-----dp 399 Lachnoclostr... CDC79182 346 --------------DESIYRLTDNTLLEKKTIVKWVVs-------nGISEAIAYVYPALDEYLKKYIFDcp--------- 395 Clostridium ... WP_037355505 361 --------------RKAIFYLTDHTSDEQICAMKCLSyyd--ytqKEISEILQRTLPQVYLYMDTFAFNesiiqv--dde 422 Selenomonas ... SEG30118 363 --------------RNSVYYLTNLSEKEELAFMQCLEkyd--ysrDELMRITEGAFPSIYSYLKRFVFDvtntkvpagee 426 Eubacterium ... WP_055062750 350 --------------EDEIYYLTDLTQPEKEKIIKWLSnygvkyskDELVSILMNVYPDLAYYLSSYRYRn---------- 405 Lachnospiraceae
WP_026654576 481 kgLEGYKLYLKEYKKSKATNKDTSYIRDYYNNGCANASNLFEMYYAIEKQDVLVEKLTderTDIYVIDGVGAEYLSLIVD 560 Butyrivibrio... WP_076004839 400 emADLLSDYFEAYKQQKISNRLEPGFLEKVDELAHSPRKFNRLPTRNEIIDGLD-KTD---TYLYWLDALGVEYLALIEA 475 Dehalogenimo... WP_092467483 393 dlSNLLTEYFDAYKRQKVSNTLETDFMEKVEKLAKS-REYNRLPTRNEIIDGLN-KDD---TYLYWLDALGVEYLAFILE 467 Desulfallas ... WP_062282325 394 glSTLLTDYFEAYKKQKVSNKLDNEFLTKVEEFAQS-RKYNRLPTRNEIIERLV-KTD---TYLLWVDALGVEYLAFISE 468 Flexilinea f... 3_ncbifamImport 381 dlSDLLTNYFSNYKEQKVSNKLNKEFIDQIEVLAEN-RIYNRLPTRNEIIDKLE-KSD---SHLYWLDALGVEYLSFFSE 455 WP_087307207 400 dfAARLTTYFERYKELKLRNLITEDFLNEVDKLARE-RIYNRLPSRDELVKKTY-SKS---TQLFWIDALGVEYLSYIIE 474 Lachnoclostr... CDC79182 396 vlSDELTEYFDLYKKQKVSNHISDEFIKLVEKYADG-ISYAQLPTRDNAIKAVSSKNN---AFLYWIDSLGVEYLSYITA 471 Clostridium ... WP_037355505 423 slADELTDYFIEYKKQKVSNKIQTEFLVKVDKIAEERPYN-RLLGRIATFKNLQCRD----DSPYFIDALGVEYLSYIKN 497 Selenomonas ... SEG30118 427 slRVVMTEYFEKYKVQKLTNKIYPEFLEEVERISTERPYN-KLQARSAVVSKMDKKN----AQLYFFDALGVEYLGYIQE 501 Eubacterium ... WP_055062750 406 ---eFLNTYFENYKYQKITNRILPSFDKVVEEQAIKMDFVTILKPRTAYVDKLDTQN----AQVFFVDAMGVEYLSFIQQ 478 Lachnospiraceae
WP_026654576 561 LLNrNsYDVEICGIATAHLPTITEVNKTYLSRLPIk----KWYLDFDRDVVHGDlYHTTCn-------LRKAFDVIEKII 629 Butyrivibrio... WP_076004839 476 LAQ-KrGLSVRVNIARAELPTITSMNRDFFDAWPGr---kEKNNELDDTKHNDVgGYNFTnnel-pihLAKEIAIIEAMI 550 Dehalogenimo... WP_092467483 468 LVR-IrGLSISINIARAELPTITSINRDFYDTWQGgr--kEKSDKLDDTKHNDKgGYNFEnnvl-pihLAKELEIISGVI 543 Desulfallas ... WP_062282325 469 LAR-SlGLSLSIYIARSELPTITIKNRGFFDDWQEsg--kEKNEELDTIKHKEAgGYNFEnnel-pihLARELEIITNVL 544 Flexilinea f... 3_ncbifamImport 456 MAR-EyGLYISIKIARAELPTITSINRNFFDDWQGns--kEKDNKLDDIKHSDEgGYNYDnnvl-pihLAKELEIIETVI 531 WP_087307207 475 LAK-RyGLKIQVEIGRALLPTITCENSDFFRNWPEdl-rhSKEEELDDIKHNDKgGYYYSsknpypihLAKELEIIERAM 552 Lachnoclostr... CDC79182 472 LAK-KkGLSIHTDIVRSDLPTITSINKQFYEQWMGgk--kYKEEQLDNIKHKDKgGYFFTddea-pihIPAELEVIEKAL 547 Clostridium ... WP_037355505 498 RCK-EyGLITEIRIAHSELPSITSLNKDYIDYFSDv---cKNTKELDEIKHG-VnYYDYEkikq-pihLLNELAVIDNVL 571 Selenomonas ... SEG30118 502 RCK-QyGLVIEISVAHCELPSITEKNKEFLHYFPQg---vLDIKELDELKHH-SqVVDYEqcke-pvhLFRELQIIDGVL 575 Eubacterium ... WP_055062750 479 KCS-EyGLSANISCARCELPSLTVFNKEFVDVLKDkgcliSDIKDLDDIKHHGKdSFDYEkekt-piyLIKELEIIDDLL 556 Lachnospiraceae
WP_026654576 630 KEIVS---ESYGKRIIITADHGATARAr-WVETPKkyGYSQSDHEGRCCKISSKNGYENNEDYIAYVdevnPEISYLISL 705 Butyrivibrio... WP_076004839 551 GKAATdlaLRHCKRFLIVSDHGASRLAvlRCKEE---QYETDTKGTHSGRCCKLFQPYDLP-FAAe----eNGYLVLADY 622 Dehalogenimo... WP_092467483 544 DKAATelaLRHYKRFLIVSDHGASRLAvlRRKEE---QYETDTKGEHSGRCCKLFEPYDLP-FAAe----eNGYLVLADY 615 Desulfallas ... WP_062282325 545 DKAATelaLRHYKRILIASDHGASRLAvlRRKEE---KYETDTKGEHSGRCCKYFEPYDLP-FAAe----eNGYLVLADY 616 Flexilinea f... 3_ncbifamImport 532 KKAATalkLRKFKRFLVVSDHGASRLAvlMKKEE---KYETNTKGEHSGRCCKLFEPYDLP-FAAe----eNGYLVLADY 603 WP_087307207 553 NDIATnlgLGKYERVVITSDHGSSRLAvlRNKEE---KYETDTKGEHSGRCCKFFPDCDLP-FAISEe--eRGYIVLADY 626 Lachnoclostr... CDC79182 548 NTAAVelgMHNCKSFIIASDHGASRLAviKKQEV---PYETDTKGEHSGRCCKSFDGCDVP-YKVe----eNGYIILSDY 619 Clostridium ... WP_037355505 572 KDIRMklsQGIIKRAIIFSDHGASRLAviNESENG--MIELEEKGKHSGRCCPVDEEPQIP-YVTYe----NGYAVLANY 644 Selenomonas ... SEG30118 576 KKIQSrlrQGQCEKAVIVSDHGASRLAviYEQENE--KLELEEKGKHSGRCCPAKEDPNIP-YVSYw----NGFAVLANY 648 Eubacterium ... WP_055062750 557 TKIKAsilAGSYNKAIIISDHGASRLAvlHETEN---IWNMETKGEHSGRCCKISEIDDKPDFAIEe----SGYWILANY 629 Lachnospiraceae
WP_026654576 706 NETSLYNRPKYEDHGGATIEEMLVPVIVanlQGSRNK-------IKYKVMDEKIQVSGLDKIVRFVINPEPESAFLIEAD 778 Butyrivibrio... WP_076004839 623 GRFKGSRAANVEVHGGASLEEVIVPIIE---LSLKNGnvt-vklVN-EVVIVDFRTGTEVILFFN--SPVQDVSVVLDG- 694 Dehalogenimo... WP_092467483 616 GRFKGSRAANVEVHGGASLEEVVVPIIE---LTLKDSnii-vemVE-KFVTVDFRTGTEMTLFFN--SPLKNVSVVLNG- 687 Desulfallas ... WP_062282325 617 GRFKGSRAANVEVHGGASLEEVVVPVIE---LKLKNEnid-islVE-PTATVDFRDGTAITLFSK--SEFEDVSIVLKG- 688 Flexilinea f... 3_ncbifamImport 604 GRFKGSRAANVEVHGGAALEEVIVPIIE---LTLKDDsgvvvelDDSKLITVDYRTGTEIILFIN--YSQDEVSVIFNN- 677 WP_087307207 627 GRFKGSRAANVEVHGGASLEEVVVPLIT---LSLNDSsie-isiVDGEKIKADPKIGIKILLFVN--KEVQDILTLSYGS 700 Lachnoclostr... CDC79182 620 GRFRGSRPANVEVHGGASLEEIVVPVIT---LTLKKQvgvkitvMHSDDITADRHEGVTLNLYISDVESPDNISLVIED- 695 Clostridium ... WP_037355505 645 ERFKGGHKAEVEVHGGATLEEVLVPIIA---ITTKSDrltyafeN--DSIERKGSEPTKLVLFCN--KEMTNPQLRVKNK 717 Selenomonas ... SEG30118 649 ERFKGGRKANVEVHGGATLEEVVVPIIF---LSKKPTdidicfvD--PVIILKGKEPATIIVFSN--IPLSEPKLVVNEK 721 Eubacterium ... WP_055062750 630 DRFRGSRRANVEVHGGASMEEVAVPIIE---ITQKASnieafivDESRVLTLGAKEYAIIKIYVG--IRSNNISIKLDGN 704 Lachnospiraceae
WP_026654576 779 GTRHELCKDGKLYTTELV 796 Butyrivibrio sp. AE3003 WP_076004839 695 KPHPATQIDANHYAVKLP 712 Dehalogenimonas formicexedens WP_092467483 688 ERYSASPLDGNHYKVALP 705 Desulfallas arcticus WP_062282325 689 KRYPAVKIDANHYSVTLF 706 Flexilinea flocculi 3_ncbifamImport 678 KRYFAEQIDNNHYKVELT 695 WP_087307207 701 MRYPSEKVDDNHYVVKIP 718 Lachnoclostridium sp. An138 CDC79182 696 KPYQAKSEDATHFTFALT 713 Clostridium sp. CAG:964 WP_037355505 718 FYSGKLIMDNKHAEFILD 735 Selenomonas sp. FC4001 SEG30118 722 VYVGEFCEDNKHAKFVMP 739 Eubacterium ruminantium WP_055062750 705 YYNAEETAEPYIYSIELK 722 Lachnospiraceae
Lu S et al.(2020). "CDD/SPARCLE: the conserved domain database in 2020.",