Conserved Protein Domain Family
anchor_AmaP

?
NF033218: anchor_AmaP 
alkaline shock response membrane anchor protein AmaP
The founding member of this family, AmaP (Asp23 membrane anchoring protein), is related to Asp23 through part of its length, but includes a highly hydrophobic N-terminal region that should make it an integral membrane protein. Asp23 (alkaline shock protein of 23 kDa), described in PMID:7864904, is a cytosolic protein in Staphylococcus aureus, strongly induced by a pH shift from 7 to 10, and also recruited to the membrane. AmaP appears to be the partner protein with an integral membrane segment and the ability to anchor Asp23 to the membrane. This model was built to identify full-length homologs of AmaP, while excluding Asp23. Some but not all members of this family score above the cutoffs of Pfam model version pfam03780.11, but full-length homologs of Asp23 score considerably higher. Asp23 family members previously were known as DUF322.
Statistics
?
PSSM-Id: 411105
Aligned: 109 rows
Threshold Bit Score: 69.5377
Created: 20-Oct-2021
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
WP_010355606   2 LRTVNRVLLGLAGLALLALGGSVLAIGLGadlptwwlhgdrhDALLTASQRTRWRDEgWWWPTVIGGLALIVLLALWWLT 81  Streptomyces ac...
WP_012370438   1 MNGFNRFLLVLIGLLGLVSVGLLVLGVYD-------------VPRLSPLLEQWQDQQ-WYSYTVLSIGGFLAFVFVILLF 66  Exiguobacterium
WP_016507796   1 MNGLNRFILVITGIVGLVSVGVLLLGVYD-------------VPRLSSYLERWQSQD-EYVYTVLAISIFLGIVFILMLL 66  Exiguobacterium...
WP_002838252   1 MSGFKKFVHILFSILLILFSLVMFFTVFN--------------FGQVSYNLREFMMN-EVCFYIFAIIGALVLIGAIFIM 65  Finegoldia magna
WP_017001186   3 VRRLKNFFLGLFIIVVVGTLLFMYLDISQ----------------ITSYQQELLKYN-WFQPTLIVCAGVLIFFGLLMFF 65  Mammaliicoccus ...
WP_002479521   1 MRRLKNFILGLIIVVVVGMLVFMLAKVPQ-------------IPQVETYQQQLLTFA-WFLPVLFTLAGLLIVLGIILVF 66  Staphylococcus
WP_016426387   1 MTRIKNFILGLLIVIIVGFLLFMYIDYKP----------------IKSYQDYFYQFN-WFYPLLIGLAAFLILIGLILFF 63  Staphylococcaceae
WP_000825819   1 MKRLKNFILGLLIVVIVGFLLFMYIQDGR----------------ITEYQDYFLQFE-WFQPLLISLAALLILIGLILVF 63  eubacteria
WP_010306730   1 MKRFISFLFGLFLLALIGVFTFLYVDNSN--------------IRQYQE--DLLAQN-WFEPTLLACAIVGLLIALGFVI 63  Kurthia senegal...
WP_010285989   1 MKRLFSFLYGLVLLVATATLLFLVIDQSS--------------WATYQE--QLRAYE-WFMPTVYIVVGVLIFIAIIMLI 63  Kurthia massili...
WP_010355606  82 A-NLRR---RRlGEVLINTGDGESAILRgSALENVLATETAHLDGVSHARVHLTG---RRDAPETQVHLRVEPHA---SP 151 Streptomyces ac...
WP_012370438  67 T-GLLSr-sKG-QRLLIRTGDGNITISK-ETIERTALESIRGINGVRTPSVHADIh-sKKETVALTVDCSVFGQE---GL 138 Exiguobacterium
WP_016507796  67 T-GLIAk-sKS-ERYTIQTGEGRITIST-EKIEKMVYESLKTFQGVRTPDVKVDId-sKRESVHVHIDCSVFNRD---GL 138 Exiguobacterium...
WP_002838252  66 FkAILSd-dLS-DFLISKDKDGEVMIST-DALENTVKRTVDKYEGIRTSNVNVRVnnsSEPYMNCDVEVGVRDMS---NI 139 Finegoldia magna
WP_017001186  66 --AAFKpthKK-PGLHRDYEDGHIYITR-NSIEKCVYRTIQKYDEVRQPNVIAKLy-nKKNNSYATIKADFFVVSetnGI 140 Mammaliicoccus ...
WP_002479521  67 --SLFApthRK-PGLYKFYKDGHIYISR-KSIEKVVYDTMANYEQLMQPNVVTKCy-sKKKKSYIDVKADFFLPDd-tHA 140 Staphylococcus
WP_016426387  64 --RAFKptyRK-PGLYKDYKDGHIYISR-KSIENTVYDTIAKYDAIRQPNVVSKLy-nKKNNSFIDITADFLVPSeatNV 138 Staphylococcaceae
WP_000825819  64 --SIFKpthRK-PGLYKDFDDGHVYVSR-KAVEKTAFDTVAKYDQVRQPNVVAKLy-nKKNKSYIDIKTDFFVPNn-vQV 137 eubacteria
WP_010306730  64 F-GLKPs-hKR-SGLYLKFNDGEIYMNK-KSIEKVVLHTIERYDAIRQPTVKAKLy-qKKKMSYIDISVDMLVAQt-dNV 137 Kurthia senegal...
WP_010285989  64 F-ALSPs-hKK-RNVALKYGDGDLMLNK-KAIEKNVRYTVAKYDDIRQPSVSVQMy-dKKKTSYIDIVVDVFIAQt-tNV 137 Kurthia massili...
WP_010355606 152 GEALRNFITHSLARARDSAalKALPAEVRM 181 Streptomyces acidiscabies
WP_012370438 139 PTIGKDIQERAKHAVESLLelPVTSTKVKI 168 Exiguobacterium
WP_016507796 139 PTLGKEIQTHVKERLEALLelPVTDVSLHI 168 Exiguobacterium sp. S17
WP_002838252 140 AGLGENIKEDIKLNLENLSgyKVKDITVKF 169 Finegoldia magna
WP_017001186 141 QSLTENMKNDIKQNVEHFSeiPVKNIEINV 170 Mammaliicoccus lentus
WP_002479521 141 RTLTENVRTDIKKNVEYFTeiPVRKLEVNV 170 Staphylococcus
WP_016426387 139 QSLVEQLRLDIKESVERFSelQVKTVKVNV 168 Staphylococcaceae
WP_000825819 138 QSLTEAIRSDIKKNVEYFTemPVRKLEVNV 167 eubacteria
WP_010306730 138 QSLLTSLKEDIKTQTEHFSemPVQDIKLNV 167 Kurthia senegalensis
WP_010285989 138 QTLIKTMRDDVKETTEHFSqlPVRDVKINV 167 Kurthia massiliensis
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap