25370690 42 GALLKQGiaalinsyaRKSFSYAPWEVKTMLIQAMVSESAARrQAEHFAVANr-ANARSEFLPAIGYTS-HRRFSVFTEF 119 thale cress 7300484 1 MKATSCRpipfinfriVRYFYRPRRLNKYYDIYRIAALVRDR--ACLFTCQQ--ASQNLQQQQPRFYSApGRRAGFFSQF 76 fruit fly 25370689 41 EPSTPDGsntyttnhdQFHFYPQQQHYPPPYYMKAGSRFTDHkAASSPAIGAptVGARLGLLQGNGFAS-HRRFSVFSEF 119 thale cress 6016367 1 ----------------------------------MLSRICGN--GIRLTRTR--LQFQPSIVTFRDYSNpAPKRGFLNNL 42 Caenorhabditis elegans 25014073 1 MAAAALR---------SGWCRCPRRCLG-SGIQFLSSHNLPH--GSTYQMRR--PGGELPLS--KSYSS-GNRKGFLSGL 63 human 25014073 1 MAAAALR---------SGWCRCPRRCLG-SGIQFLSSHNLPH--GSTYQMRR--PGGELPLS--KSYSS-GNRKGFLSGL 63 human 6016371 1 --------------------------------MFLSRKITKN-ARTIVQCQR--------FFQTSIFSQnAAPQSPIKVF 39 fission yeast 400272 1 -------------------------MHRSTFIRTSGTSSRTLtARYRSQYTGl-LVARVLFSTSTTRAQgGNPRSPLQIF 54 baker's yeast
25370690 120 SKNIRGEAHSNPEFERTVKELKERTEEFKGVTEDLKVRTKQTTEKLYKQADALTVQVSSSvkdklsaaseEVKESFKLGK 199 thale cress 7300484 77 FDNMKAEMDKNKEIKDNIRKFREEAQKLEESDALKSARQKFNIVESEAQKSSSMLKEQLG----------AIKERVGDVL 146 fruit fly 25370689 120 SKKIRGEADSNPEFQKTVKEFKERAEELQGVKEDLKVRTKQTTEKLYKQGQGVWTEAESva--------kKVKESFKLGK 191 thale cress 6016367 43 IDNVRDEMQKNKELQEHQQQLKARMQELNESDALKDARKKFEIVEKETLKSSEVVKQKIE----------ELSDHMKKMV 112 Caenorhabditis elegans 25014073 64 LDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLG----------ELTGTVKESL 133 human 25014073 64 LDNVKQELAKNKEMKESIKKFRDEARRLEESDVLQEARRKYKTIESETVRTSEVLRKKLG----------ELTGTVKESL 133 human 6016371 40 MDTFRAELKKSQELQDSVKALQDSSGSLSESDTFKKARDAYEKARSGTTAASSFTGKTVG----------KAGAKIGSYA 109 fission yeast 400272 55 RDTFKKEWEKSQELQENIKTLQDASGKLGESEAYKKAREAYLKAQRGSTIVGKTLKKTG--------------ETMEHIA 120 baker's yeast
25370690 200 EENAESASSSGTRASQGEKQQ--SGSTEELHTFFAKFKSSLSSPKVSEVFYRLKeaKPFDIVKQALDIVKDELRGNPSRK 277 thale cress 7300484 147 EDASKSHLAKKVTE--EL-SKkaRGVSDTISDTSGKLGQTSAFQAISNTTTTIK--KEMDSASIENR-VYRAPAKLRKRV 220 fruit fly 25370689 192 EESAESASSSGTGTTEGEKQQqqSGSTEEQDTFFGKFKSSISSPKLSEAFH-----KPLDFAKKGLDIVKDELRGNPSKR 266 thale cress 6016367 113 HEIQKTEAGKKMTEAGAEALKqaRKAAEHVEKVAEKVGDTEVYKHVSTSMKTVK--DEIDNIADVRM--YSRPEALTKRT 188 Caenorhabditis elegans 25014073 134 HEVSKSDLGRKIKEGVEEAAKtaKQSAESVSKGGEKLGRTAAFRALSQGVESVK--KEIDDSVLGQTGPYRRPQRLRKRT 211 human 25014073 134 HEVSKSDLGRKIKEGVEEAAKtaKQSAESVSKGGEKLGRTAAFRALSQGVESVK--KEIDDSVLGQTGPYRRPQRLRKRT 211 human 6016371 110 QKAWESAPVQLSKKVISSt---aNTVATGVDTATKPVRETAFYKTIKQTMS-----DGSTSSRYGFYADKEQRKKLREEF 181 fission yeast 400272 121 TKAWESELGKNTRKa-------aAATAKKLDESFEPVRQTKIYKEVSEVID------DGESSRYGGFITKEQRRLKRERD 187 baker's yeast
25370690 278 KFLEHTPPPPFTGERSMRTEMVVTQTKqSKLQQKWESFREKMQGSPVFKRLS-GMSEPVVNKSQEIAEDVREIWETSDNP 356 thale cress 7300484 221 QLVMS--DSDRVVEPNTEATGMELHKD-SKFYESWENFKNNNTYVNKVLDWK-VKYDESENPVIRASRLLTDKVSDVMGG 296 fruit fly 25370689 267 KHLEYTPPPPFTGERSTRTEMVIMPTKqSKWQKKWESLREKMQGYPVFKRLS-GMSEPVVNKSQEIAEDVREKWETSDNP 345 thale cress 6016367 189 DGFDL--EKERVVEANDSATDVTLHKD-SKWYSGWKNFSESNTYYHKLLDWK-IKYDESDNMAVRMMRGVTEKIGSVFSG 264 Caenorhabditis elegans 25014073 212 EFAGDKFKEEKVFEPNEEALGVVLHKD-SKWYQQWKDFKENNVVFNRFFEMK-MKYDESDNAFIRASRALTDKVTDLLGG 289 human 25014073 212 EFAGDKFKEEKVFEPNEEALGVVLHKD-SKWYQQWKDFKENNVVFNRFFEMK-MKYDESDNAFIRASRALTDKVTDLLGG 289 human 6016371 182 ERRNRMFASSARIQPNEDVQSVVVHSN-PSWKNKVEQIKNESRLVRKIQELK-KSYQESEHPIVSSIRDMADSISGVWSR 259 fission yeast 400272 188 LASGKRHRAVKSNEDAGTAVVATNIESkESFGKKVEDFKEKTVVGRSIQSLKnKLWDESENPLIVVMR----KITNKVGG 263 baker's yeast
25370690 357 IVHKIQDMnekflketdsaSTYKEIRSRDPSFSLPDFAAEIEEVIKP-VLNAYSEGDVETLKKYCSKEVIERCTAERTAY 435 thale cress 7300484 297 LFSKTELS-----------ETMTELVKIDPSFDQKDFLRDCETDIIPnILESIVRGDLEILKDWCFESTFNIIANPIKEA 365 fruit fly 25370689 346 IVHKIQES-----------------------FSLPDFVSEIQEAIRP-VLNAYSKGDAKTLKKYCSKELIERCTAEHRAF 401 thale cress 6016367 265 ---QNEVS-----------EVLTEIHKIDANFDKQEWLRFCETKIIPnILEAFIRFDLEVLQSWCHERAYTQLSTVVKEY 330 Caenorhabditis elegans 25014073 290 LFSKTEMS-----------EVLTEILRVDPAFDKDRFLKQCENDIIPnVLEAMISGELDILKDWCYEATYSQLAHPIQQA 358 human 25014073 290 LFSKTEMS-----------EVLTEILRVDPAFDKDRFLKQCENDIIPnVLEAMISGELDILKDWCYEATYSQLAHPIQQA 358 human 6016371 260 MFSETEAS-----------QVMRRFKEIDPSFNTEHFLQYLREYIVPeVTEAYVKGDKEVLKTWLSEAPFSVYETTTKEY 328 fission yeast 400272 264 FFAETESS-----------RVYSQFKLMDPTFSNESFTRHLREYIVPeILEAYVKGDVKVLKKWFSEAPFNVYAAQQKIF 332 baker's yeast
25370690 436 QTHGVLF-DNKLLHISEVSVSVTKMMG--DSPIIIAKFQTQEIYCVRDEN-GEIQEGGQDTIHTVYHEWAMQQvETTELG 511 thale cress 7300484 366 KKAGVYL-DSKILDIENIELAMGKVME--QGPVLIITFQAQQIMCVRDQK-SQVVEGDPEKVMRVHYVWVLCR-DRNELN 440 fruit fly 25370689 402 TSQGYFF-DHKLLHVSEVDIQETKMMG--TTPVIIVRFQTQEIFCVRDQD-GKIKEGGQDTIHTVYYDWAMQQvDAAELG 477 thale cress 6016367 331 QKMHFSTkDSRIIDINKVEMATGKMME--QGPVLIISFQVYMINVTKNAD-GKVVEGDPDNPKRINHIWVLCR-DVEEYN 406 Caenorhabditis elegans 25014073 359 KALGLQF-HSRILDIDNVDLAMGKMME--QGPVLIITFQAQLVMVVRNPK-GEVVEGDPDKVLRMLYVWALCR-DQDELN 433 human 25014073 359 KALGLQF-HSRILDIDNVDLAMGKMME--QGPVLIITFQAQLVMVVRNPK-GEVVEGDPDKVLRMLYVWALCR-DQDELN 433 human 6016371 329 AKHGVVS-VGKILDIRGVDIMSQRLLQpnDIPVFIVTFRTQEVHMFKDASsGELVAGKDDRIQQCTYASVFTR-VEDELD 406 fission yeast 400272 333 KEQDVYA-DGRILDIRGVEIVSAKLLApqDIPVLVVGCRAQEINLYRKKKtGEIAAGDEANILMSSYAMVFTR-DPEQID 410 baker's yeast
25370690 512 EDAiYPIWRLREMCRNGVQALI 533 thale cress 7300484 441 P---KAAWRLMELSANSSEQFV 459 fruit fly 25370689 478 EDAiYPIWRLREMLRAGVQALI 499 thale cress 6016367 407 P---ALAWKLLEVHMQETPLAL 425 Caenorhabditis elegans 25014073 434 P---YAAWRLLDISASSTEQIL 452 human 25014073 434 P---YAAWRLLDISASSTEQIL 452 human 6016371 407 NPE-TRGWRIVDFARARAVDYF 427 fission yeast 400272 411 DDE-TEGWKILEFVRGGSRQFT 431 baker's yeast
Jiyao W et al.(2023). "The conserved domain database in 2023.",