15235308 1 MAPVPDPNSVGGGAKRDEATTKIPSKDSKKKDDKKEEDLSEEDLQLKQNLELYVERVQDPNPELQKIALESMRKEIRDST 80 thale cress 25348002 1 MAPTQDPNSVGGGAKKDEATLKVPSKDPKKKDEKKDEDLSEEDLELKQNLELYVERVQDPNPELQKAALESMRQEIRAST 80 thale cress 15236408 1 -------------------------------------------------------MVQDPNPDLQKAALESMRQEIRALT 25 thale cress 17542008 1 --MVATTQQTPKEA----DKKKADDKKVPEKAEPKKEEMSEEDQKLEEDLNLLVQRLSEPDTTLYKPSLETMRTLIRAST 74 Caenorhabditis el... 19074108 1 --------------------------------------------MEEGELKIIVERIQDPDIDIQNNALNMLFDVTKSSH 36 Encephalitozoon c... 19861832 8 SKSPSGNDALNDKKGTKTSETNDRNSTNNTKERDELEDLSEEDLQLKNDLELLVQAVQDATPELVGSSLTQLKEIIRTST 87 fission yeast 731642 6 DK----KQQTIDEQSQISPEKQTPNKKD--KKKEEEEQLSEEDAKLKTDLELLVERLKEDDSSLYEASLNALKESIKNST 79 baker's yeast 6174930 7 DKAPVQPQQSPAAAPGGTDEKPSGKERRDAGDKDKEQELSEEDKQLQDELEMLVERLGEKDTSLYRPALEELRRQIRSST 86 human
15235308 81 SSMTSVPKPLKFLRPHYGVLKEFHAKMAESDLKKMLADILSVLALTMSAEGERicvlwflvefdlsylllilcyailfqe 160 thale cress 25348002 81 SSMTSVPKPLKFLRPHYGTLKAFHETMADSDLKKYLSDILSVLALTMSADGERe-------------------------- 134 thale cress 15236408 26 SSMTSVPKPLKFLRPQYVTLKAFHETMADSNLKKYISDILSVLALTTLYRLHYflitrr--------------------- 84 thale cress 17542008 75 TSMTSVPKPLKFMRPHYNKMKEIFTSIVAPDVKKLCADIISVLAMTSDERTDT--------------------------- 127 Caenorhabditis el... 19074108 37 SKSIDTIN-FQYLADNLDVLEDVCKRLE-GNKKRWLCDIISAICVVDDERKLL--------------------------- 87 Encephalitozoon c... 19861832 88 SSMTAVPKPLKFLRPHYFTLVKIYDSWPQSPQKTQLADILSVLGMSYSNTSKHe-------------------------- 141 fission yeast 731642 80 SSMTAVPKPLKFLRPTYPDLCSIYDKWTDPNLKSSLADVLSILAMTYSENGKHd-------------------------- 133 baker's yeast 6174930 87 TSMTSVPKPLKFLRPHYGKLKEIYENMAPGENKRFAADIISVLAMTMSGEREC--------------------------- 139 human
15235308 161 sLNYRLNGSESDIGSWGHEYVRNLAGEIAKEYTI-RQGEES---------------------SIEDLMDLVQQIVSFHMK 218 thale cress 25348002 135 sLRFRLIGTEGDIGSWGHEYVRNLAGEIAQEYTK-RQSEEA---------------------SIDDLMELVQQIVAFHMK 192 thale cress 15236408 -------------------------------------------------------------------------------- thale cress 17542008 128 -INYRILGSHEPIGDWGHEYVRHLAMEMSEEWKK-EGTSDA---------------------RKAELLKLTQDIVSHHMK 184 Caenorhabditis el... 19074108 88 --AYRVEGNIIDLKEWGHLYVKKLIGCIADVKNN--KMDFP----------------------FAKTRDVGRECIDFLFK 141 Encephalitozoon c... 19861832 142 sLKYRLQGVTTDPSLWGHEYVRHLASEIEEEFASrQEEEAP---------------------T-DDLMELALTIVPFFLT 199 fission yeast 731642 134 sLRYRLLSDVSDFEGWGHEYIRHLALEIGEVYNDqVEKDAEdetssdgsksdgsaatsgfefSKEDTLRLCLDIVPYFLK 213 baker's yeast 6174930 140 -LKYRLVGSQEELASWGHEYVRHLAGEVAKEWQElDDAEKV---------------------QREPLLTLVKEIVPYNMA 197 human
15235308 219 HNAETEAVDLLMDVEDLDLLLEHVDNTNFRRTCNYLTSAAKYLPGPDDMLVLDIAYMIYIKFAEYPNALQIALFLDNMQY 298 thale cress 25348002 193 HNAETEAVDLLMDVEDLDLLLEHVDKTNFKRTCNYLTSAARYLPGPDDMLVLDISYMIYMKFEEYPNALQIALFLDNTQY 272 thale cress 15236408 -------------------------------------------------------------------------------- thale cress 17542008 185 HNAEVEACDLLIEIERIDLLISYVQEVDHQRVCLYLLSCAPLTPDPDNIILIRTALQLYLKFNRYLEAVRCAIMVNDIPQ 264 Caenorhabditis el... 19074108 142 HNAEFEAIDFLVEVGGIETVLDYVDTHNYNRIVLYLEDMNSFV---D---LEEVILKIYLKMGDHSRYVVGLIRRQKSKE 215 Encephalitozoon c... 19861832 200 HNAEADAIDLLQELGAIEKVVPFVELDNASRVCLYITSCVNLLPFPEDVAMLRTAHAIYRKFDQLTQALNVAIRLDDMSL 279 fission yeast 731642 214 HNGEEDAVDLLLEIESIDKLPQFVDENTFQRVCQYMVACVPLLPPPEDVAFLKTAYSIYLSQNELTDAIALAVRLGEEDM 293 baker's yeast 6174930 198 HNAEHEACDLLMEIEQVDMLEKDIDENAYAKVCLYLTSCVNYVPEPENSALLRCALGVFRKFSRFPEALRLALMLNDMEL 277 human
15235308 299 VKQVFTSCTDLVKKKQFCYMIARHGMTFELDqemvAndedKEALQDIVNNSKLSEGYLTLARDIEVMEAKTPEDIYKAHL 378 thale cress 25348002 273 VKQVFTSCTDLLKKKQFCYMIARHGITFELDdemvAddddREALQDIVNNTKLSEGYLTLARDIEVMEAKTPEDIYKAHL 352 thale cress 15236408 -------------------------------------------------------------------------------- thale cress 17542008 265 VHQIFAKASDPLLRKQMAILLGRHQIFLDY-----EgsadSDALAELNSNAHLYEYFHSLARELDIMEPKTPEGIYKSHL 339 Caenorhabditis el... 19074108 216 AIEYVRSIEDRDYKKQCLYILARCNLYYEAS---------DPEEKYILSNGYIKDVYREIGAELEIDKPSKMDAILKGFK 286 Encephalitozoon c... 19861832 280 IKEDCEAATDPLLKKQMSYMLARQQIPMDMG----D-----EELNDALNNTHLSDHFHYLGKELNLMDPKVPEDIFKTHL 350 fission yeast 731642 294 IRSVFDATSDPVMHKQLAYILAAQKTSFEY-----------EGVQDIIGNGKLSEHFLYLAKELNLTGPKVPEDIYKSHL 362 baker's yeast 6174930 278 VEDIFTSCKDVVVQKQMAFMLGRHGVFLELS----EdveeYEDLTEIMSNVQLNSNFLALARELDIMEPKVPDDIYKTHL 353 human
15235308 379 LDGR-ASSGPSVDSARQNLSATFVNAFVNAGFGQDKLMTVPSDstsgSAGNWLFKNKEHGKTSAVASLvylilldklisy 457 thale cress 25348002 353 LDGR-ASSGASVDSARQNLAATFVNAFVNAGFGQDKLMTVPSDsttgSSGNWLFKNKEHGKTSAAASL------------ 419 thale cress 15236408 -------------------------------------------------------------------------------- thale cress 17542008 340 EHSRpFGNSAQPDSTRMNLAAALVNGFVNCGFGVDKMMAETE-----EASRWFYKNKEYGMLTAAASQ------------ 402 Caenorhabditis el... 19074108 287 YDKD-------T---RQLASIGIANGFVHMGYGRDPIFLPQEGd---SRVPLDYEAILGCDVPDLISVfg---------- 343 Encephalitozoon c... 19861832 351 EVARtGLGASGVYSAKQNLANTFVNALVNAGYSNDRLILVDDE-----KTSWIYKNKESGLISATASI------------ 413 fission yeast 731642 363 DNSKsVFSSAGLDSAQQNLASSFVNGFLNLGYCNDKLIVDND--------NWVYKTKGDGMTSAVASI------------ 422 baker's yeast 6174930 354 ENNRfGGSGSQVDSARMNLASSFVNGFVNAAFGQDKLLTD-------DGNKWLYKNKDHGMLSAAASL------------ 414 human
15235308 458 vfileGMIQLWDVETGLGHLDKYFHSNDNPVVAGALLGVGIVNCGIKN-DCDPAFALLSGYIDNEDSSVRIGAIMGLGIA 536 thale cress 25348002 420 -----GMIQLWDVDSGLSQLDKYFHSNDNPIIAGALLGVGIVNCGIKN-DCDPALALLGDYIDKEDSSVRIGAIMGLGIS 493 thale cress 15236408 -------------------------------------------------------------------------------- thale cress 17542008 403 -----GLIWRWDIDTGLAQCDRFLYINDDYIKAGTLLAIGIISSGIQD-ACDPASALLLDHVQSDRSIMRVGSILGLGLA 476 Caenorhabditis el... 19074108 344 ---siGVIESWNSEKVMETLQEHIFADFSYRKTGSLLGLALSGLRNFE-ERPAILALLSNNLQSSSSIHVIATLLGIEAM 419 Encephalitozoon c... 19861832 414 -----GLLQLWNVDMGLSLLDKYLYSSEENTKAGALLGIGVTNVAVRN-EADPAMAILSEYLETGSVKLRASAILGLGLA 487 fission yeast 731642 423 -----GSIYQWNLD-GLQQLDKYLYVDEPEVKAGALLGIGISASGVHDgEVEPALLLLQDYVTNPDTKISSAAILGLGIA 496 baker's yeast 6174930 415 -----GMILLWDVDGGLTQIDKYLYSSEDYIKSGALLACGIVNSGVRN-ECDPALALLSDYVLHNSNTMRLGSIFGLGLA 488 human
15235308 537 YAGSQNDQIKi--------rLSPILNDANAP--LDVIAFAALSLGMIYVGSCNEEVAQSIIFALMDRSEAELGEALTRFL 606 thale cress 25348002 494 YAGSQNDQVLir------nkLSPILNDAKAP--LDVIAFASLSLGMIYVGSCNEEVAQSIIFALMDRSEAELGDALTRFL 565 thale cress 15236408 -------------------------------------------------------------------------------- thale cress 17542008 477 YANSKRETVTkneergvifeLKKVLSDQKPSaiPEVKGLAGLSLGLILVGTADAEAAMEMLQALMDKSETELTDPNMRFL 556 Caenorhabditis el... 19074108 420 FSGTQAEevr--------elLQPLMFSDSSE----VVFFTSFTLGSVFCGSADEDLTSLMLQTFVEKGK-ESETQFFRFL 486 Encephalitozoon c... 19861832 488 YSGANREdll--------dmLSPIVTDTDCP--MQLSCLAALSLGLIFVGTCNGDVASTILQTLMEREESAQNDQWGRFM 557 fission yeast 731642 497 FAGSKNDevl--------glLLPIAASTDLP--IETAAMASLALAHVFVGTCNGDITTSIMDNFLERTAIELKTDWVRFL 566 baker's yeast 6174930 489 YAGSNREdvl--------tlLLPVMGDSKSS--MEVAGVTALACGMIAVGSCNGDVTSTILQTIMEKSETELKDTYARWL 558 human
15235308 607 PLGLGLLYLGKQvgsqsyliiflvrESVEATAEVSKTFNEKIRKYCDMTLLSCAYAGTGNVLKVSDqfsltlqtiqtiqv 686 thale cress 25348002 566 PLGLGLLYLGKQ-------------ESVEATAEVSKTFNEKIRKYCDMTLLSCAYAGTGNVLKV---------------- 616 thale cress 15236408 -------------------------------------------------------------------------------- thale cress 17542008 557 ALGIALIFLQTQ-------------DKSDVFVESLRSLPDPFGAMVSTLVEVCAYAGTGNVLKI---------------- 607 Caenorhabditis el... 19074108 487 MLGLASLFYRRK-----------------DVECGIMEIGGALSKHESILIKGFQYVGTGDSNVIES-------------- 535 Encephalitozoon c... 19861832 558 ALGLALLFNGKQ-------------DLADATVETLKAIEGKIARQAEILVDICSYAGTGNVLHIQKll------------ 612 fission yeast 731642 567 ALALGILYMGQG-------------EQVDDVLETISAIEHPMTSAIEVLVGSCAYTGTGDVLLIQDll----------hr 623 baker's yeast 6174930 559 PLGLGLNHLGKG-------------EAIEAILAALEVVSEPFRSFANTLVDVCAYAGSGNVLKV---------------- 609 human
15235308 687 QDLLAQCGEHLVKGDIHQG------------------------------------------------------------- 705 thale cress 25348002 617 QDLLAQCGEHLEKGDIHQG------------------------------------------------------------- 635 thale cress 15236408 -------------------------------------------------------------------------------- thale cress 17542008 608 QKLLHLCSEHYETPAAEKKtaasrgprgpapaaatparpaaqpgnvnvagtpaptgtpava-----------paaprrdl 676 Caenorhabditis el... 19074108 536 ILTDSFTGDTDALLES---------------------------------------------------------------- 551 Encephalitozoon c... 19861832 613 ----hICSEPPSDDakese------------------------------------------------------------- 627 fission yeast 731642 624 LTPKNVKGEEDADEEETAEgqtnsisdflgeqvneptkneeaeievdemevdaegeevevkaeitekkngeslegeeiks 703 baker's yeast 6174930 610 QQLLHICSEHFDSKEKEEDkdkkekkdkdkk------------------------------------------------- 640 human
15235308 706 ----------------------------------PAVIGLAMVAMSEELGLDMEIRSLERVLQYGEQNIRRAVPLALGLL 751 thale cress 25348002 636 ----------------------------------PAVLGLAMVAMSEELGVDMEIRSLERMLQYGEQNIRRAVPLALGLL 681 thale cress 15236408 -------------------------------------------------------------------------------- thale cress 17542008 677 pgaasaatpgapetaaadatpappakpdlssqqaVAVLGIGLIAMGDDIGSQMALRMFGHLIRYGEPVIRRAVPLALSLL 756 Caenorhabditis el... 19074108 552 ----------------------------------LGLLSCALVSMGDETSSQMVGRIVSSSLLLDSSHLRSVLPLCYSIL 597 Encephalitozoon c... 19861832 628 -----------------------------ttiqtFAALGVATIAMGEDIGAEMVLRHFDHMMHYGEPSIRKAIPLALGLL 678 fission yeast 731642 704 eekkgkssdkdattdgknddeeeekeagivdelaYAVLGIALIALGEDIGKEMSLRHFGHLMHYGNEHIRRMVPLAMGIV 783 baker's yeast 6174930 641 -----------------------eapadmgahqgVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALI 697 human
15235308 752 CISNPKVTVMDTLSRLSHDTDSEVAMAAIISLGLIGAGTNNARIAGMLRNLSSYYYKDASLLFCVTfydfflsfhgintv 831 thale cress 25348002 682 CISNPKVTVMDTLSRLSHDTDSEVAMSAIISLGLIGAGTNNARIAGMLRNLSSYYYKDMSLLFCVR-------------- 747 thale cress 15236408 -------------------------------------------------------------------------------- thale cress 17542008 757 SVSNPQLNILETLSKFSHDSDADTAHNAIFAMGLVGAGTNNARLVAMLRNLASYHYKDQVSLMLVR-------------- 822 Caenorhabditis el... 19074108 598 YPSNPQVNVLDMLEKSLNIGETNCIISTIVSLGLIGAGTLNSRITKILDQQYSYYYKDSKVLPVLK-------------- 663 Encephalitozoon c... 19861832 679 SASNPQMRIFDTLSRYSHDNDLDVAYNAIFAMGLVGAGTSNARLAQLLRQLASYYHKESNALFMVR-------------- 744 fission yeast 731642 784 SVSDPQMKVFDTLTRFSHDADLEVSMNSIFAMGLCGAGTNNARLAQLLRQLASYYSREQDALFITR-------------- 849 baker's yeast 6174930 698 SVSNPRLNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFMVR-------------- 763 human
15235308 832 stydrlVLIVLSHnagahrsrvcaYGKGSLNSQSFPLRTALAMPTALAGIVTLLHACLDMKsIILG-KYHYVLYFLVLAM 910 thale cress 25348002 748 ------IAQGLVH-----------MGKGLLTLSPFHSERFLLSPTALAGIVTLLHACLDMKpIILG-KYHYVLYFLVLAM 809 thale cress 15236408 -------------------------------------------------------------------------------- thale cress 17542008 823 ------IAQGLTH-----------LGKGTMTLNPWHSDRQLLSPSALASLLSICFSFLDANnTILNnRQHYLLYTLVLAM 885 Caenorhabditis el... 19074108 664 ------IAQGLVS-----------LGKGLLSISPLYFDKTTFMPKNTIGLFSTVFMLLDSS-ISPLvSSHAYMFFLLCQA 725 Encephalitozoon c... 19861832 745 ------IAQGLLY-----------LGKGTMTLNPYHTERQILGQTAFAGLMTVVLAMLDAN-TFVLdTSHWLLYAITLAI 806 fission yeast 731642 850 ------LAQGLLH-----------LGKGTMTMDVFN-DAHVLNKVTLASILTTAVGLVSP--SFMLk-HHQLFYMLNAGI 908 baker's yeast 6174930 764 ------LAQGLTH-----------LGKGTLTLCPYHSDRQLMSQVAVAGLLTVLVSFLDVRnIILG-KSHYVLYGLVAAM 825 human
15235308 911 QPRMMLT-VDQSLKP-----ISVPVRVGQAVDVVGQAGRPKTITGFQTHSTPVLLAAGERAELATEKYvVPLIPLLHYpt 984 thale cress 25348002 810 QPRMMLT-VDENLKP-----LSVPVRVGQAVDVVGQAGRPKTITGFQTHSTPVLLAAGERAELATDKY-IPLSPILEG-- 880 thale cress 15236408 -------------------------------------------------------------------------------- thale cress 17542008 886 QPRMLTTlVEDEMKPgslkqLNVSVRVGQAVDVVAQAGKPKTITGFQTHTTPVLLAHGERAELANDEY-LSVTPHLEG-- 962 Caenorhabditis el... 19074108 726 CTQKYVT----CSEK-------INIRVGHPINTVGMVGEPKKLSSVQTHTSPVVLSEKIRAETDENVC----SSYIED-- 788 Encephalitozoon c... 19861832 807 RPRMLIT-LGEDGQY-----LPVSVRVGQAVDVVGQAGRPKVITGWVTHTTPVLLHHNERAELATEAY-TPLTS-LEG-- 876 fission yeast 731642 909 RPKFILA-LNDEGEP-----IKVNVRVGQAVETVGQAGRPKKITGWITQSTPVLLNHGERAELETDEY-ISYTSHIEG-- 979 baker's yeast 6174930 826 QPRMLVT-FDEELRP-----LPVSVRVGQAVDVVGQAGKPKTITGFQTHTTPVLLAHGERAELATEEF-LPVTPILEG-- 896 human
15235308 985 rnktlFYILESKKTLLL 1001 thale cress 25348002 881 -----FIILKEnpdyre 892 thale cress 15236408 ----------------- thale cress 17542008 963 -----LVILKKNPDYQP 974 Caenorhabditis elegans 19074108 789 -----VLILKKN----- 795 Encephalitozoon cuniculi 19861832 877 -----IVILKKNTEDIE 888 fission yeast 731642 980 -----VVILKKNPDYRE 991 baker's yeast 6174930 897 -----FVILRKNPNYDL 908 human
Jiyao W et al.(2023). "The conserved domain database in 2023.",