7296422 4 HAFH-RPGPLKQANKAHKTgR-HRSKGAIDNAQKGKIGLRPIS---HKHKQQQRKEQRRNQMNQLRKNKREEVLEQ--KR 76 fruit fly 17533085 3 TTGH-RAGVFKKPSKPHKSwKgKRTKGEITSENRGREGVKQLTrsaHSTHRTISKDARRNQLKMARDQKMADAMERrrTS 81 Caenorhabditis elegans 19074063 -------------------------------------------------------------------------------- Encephalitozoon cun... 17438157 1 MAAH-HSSPLKMQNKAHKSgQ-HRGRGSAQQDGKGHLALKTLS---KKVRKELSRVDQRHSASQLQKQKKEVVLAEkrQL 75 human 8922496 1 MAKV-ADTILFLLDPLEG------------WDSTGDYCLSCL------------------FAQGLP------------TY 37 human 19114303 1 MAHH-HRSTFK-AKKPFKS-K-HASKSSLKEKYKNEVEPHRSGp--KNIVHTSTKADRRNTAKQIQLNKRTEVAMN--NR 72 fission yeast 6320143 1 MAGHsHRSSLKNGHKSYKS-K-HASKGALKRLYKGKVEKEPVGt--GKPDKQVSKLQRKNKAKQLRAQRILDSIEN--RK 74 baker's yeast
7296422 77 KLGGQNTAPFLVCLLPMHEQIDPMSALEilks-cdsELVVENSPSGIV--YINLPRFKQRFAFVTPpvgRGNELIALDYL 153 fruit fly 17533085 82 NAPCLVTVVSLGVGARPTEFIKKLATCD--------ETIIQTTSPSTI--DFAIPRFKSRVSFLTPd--KDNVDGVLDAI 149 Caenorhabditis elegans 19074063 -------------------------------------------------------------------------------- Encephalitozoon cun... 17438157 76 ALAVQGLS-----GLPLKKQID---------------------------------------------------------- 92 human 8922496 38 TLAVQGIS-----GLPLKKQID---------------------------------------------------------- 54 human 19114303 73 IFGGKNGAPKVITIVPLCNNVDSWNVLTnllrsidpEASLPKFDKDSIsySTTIDRFKQNLLFLLP---KREFYSLIDAC 149 fission yeast 6320143 75 LFEGKNGAAKIITIVPLVNDLDPLDILYkllkcaddEGIMVQEVDSKRifNVHIKKFKSNLKIIIPd--MTNFLNILDCA 152 baker's yeast
7296422 154 KVCDTTLLLTTAAfgddEIFDRWGQRIFNMMSAQGIPTPVVALMDLESIN--PKRRPAAKQAAQKVISKLLPEEK-IMQL 230 fruit fly 17533085 150 RASDVLCFLWPMS----AELSEWDEQLLTIIKANGLPTIVSVVPGLGSIAn-HKKKEDVRKGIEFIISKWSMSNAgVMPA 224 Caenorhabditis elegans 19074063 1 -----------------------------------------------------------MKARDRRNRTKMKSIGsIARI 21 Encephalitozoon cun... 17438157 93 ----------------------------------------------------------ARKKLSKAVEKHFLDDK-LLLL 113 human 8922496 55 ----------------------------------------------------------TRKKLSKAVEKRFPHDK-LLLL 75 human 19114303 150 KVSDYVIFVLSAV----QEVDEFGELIVRTTQGQGISSVLSMVHDLSEVDs-LKTRNEVKKSLQSFMNFFFSDQErVFAA 224 fission yeast 6320143 153 KVADFVVFGLSGVq---EVDEEFGEQIIRALELQGIASYIGVISNLSAVHekEKFQLDVKQSLESYFKHFFPSEErVYNL 229 baker's yeast
7296422 231 DTASEALNVMRRIGGQKKRILHNVANRPHLFGDVVEFKpgSDPSDDLGTLEVTGFLRGQSLNVNGLVHIPGLGDFQLSQV 310 fruit fly 17533085 225 DSVTDNLQLLRILNETKKKPLTLQARHSYML---VENLecSDKTGETCTLVAQGYLRGPEWNANNLVHLPGFGDFQISKI 301 Caenorhabditis elegans 19074063 22 KESKLPYSLPHGPYVVVSVVSLGRECEGYFDKYLHGN---GGLFYSEECKMNFLFKRTDELSEFQLGYVCRVSDIVVFFI 98 Encephalitozoon cun... 17438157 114 DTQQEAGMLLRQLANQKQWHLAFRDQQAYLFAHTADFVp-SEENNLVGTLEISGYVRGQTLNVNRLLHITGRGDFQMKHI 192 human 8922496 76 DTQQEAGMLLRQLANQKQQHLAFRDRRAYLFAHAVDFVp-SEENNLVGTLKISGYVRGQTLNVNRLLHIVGYGDFQMKQI 154 human 19114303 225 DVSQDALNVMRALCTSHPRGIHWRDSRSYLLS--------QEISYSNGNLLVRGIVRGKGLDPNRLIHIQGFGDFAINRI 296 fission yeast 6320143 230 EKNSDALNVLRTLCQRLPRSINWRDNRGYVVADFVDFV--ET-SPDSGDLVIEGTVRGIGFNANRLVHIPDFGDFQLNKI 306 baker's yeast
7296422 311 -VAPP---DPYKLDKSRDg-ENSEVRLLDRSDP-SKRTSLQSE---NIPDPMDAEQT-----WPTE----DEIAASQAET 372 fruit fly 17533085 302 -ESTV---DPHPLKAHN---KTPEAQIIAKSD--DKRQNTETE---ITPDSMDGEQT-----WPTR----EELEEA---- 356 Caenorhabditis elegans 19074063 99 dSNEIdgsKLKIIKKFIP---SCLFCISTQSLR-DAAKKFVRR---HFPKERIVEIG-----GLMD----ALSNVRIKNT 162 Encephalitozoon cun... 17438157 193 -DDPM---DPFPLNPTV---------IKSQKDP-DMAIEICAM---DTVDDMEEDLK-------CE----DE-------- 236 human 8922496 155 -DAPG---DPFPLNPRG---------IKPQKDP-DMAMEICAT---DAVDDMEEGLKvlmkaDPCR----QESLQAEVIP 213 human 19114303 297 yEAPQgiqNSRGISMDED--TNLTGGLVELCSPtQEQDSLESLg--PIIDDMDTDMDsevgkEASRgvrlDDFYYFDDEE 372 fission yeast 6320143 307 eKISEssqKRKIIKEKATdsLSLELDLQTVFESnMNRDTLDEYapeGTEDWSDYDEDfeydgLTTAr--yDDHGFLPG-R 383 baker's yeast
7296422 373 KKMKLVKRVP--------KGYSEYQAAWIPDveevedpdgkddddmsEDDDDDKEDDNEDFMSCDNKSFEDEyekrDSDT 444 fruit fly 17533085 357 D--KELRRVP--------KGTSSYQAAWILD----------------DEDDEDEEDSDEDMDDSDNEEVED-----DSEE 405 Caenorhabditis elegans 19074063 163 SVCRRPYIVPs-------NAYSDGEYFYVEGfl-------------kHGFLSDKVIVNGQYEMTIEEVFADR----AYKG 218 Encephalitozoon cun... 17438157 237 -------------------------------------------------------------------------------E 237 human 8922496 214 DPMEGEQTWPteeelseaKDFLKESSKVVKKvpkgtssyqaewildgGSQSGGEGDEYEYDDMEHEDFMEEEsqdeSSEE 293 human 19114303 373 EPVAVAKRVP--------KGTSTYQATWIPD----------------EDEESDQYSDVEDTEVIIEDQDNQEi--sNHVA 426 fission yeast 6320143 384 EQTSKKAAVP--------KGTSDYQAKWYLDdvi----------danEEEEAEQTNGKDETMMEIDDEMMVE-----QDN 440 baker's yeast
7296422 445 EEFQDTVSVAS-E---AAINDEKYDQQMDFQE-ERETLKKLQQART-DQLWPDEIDTPLDVPARERFQKYRGLESFRTSP 518 fruit fly 17533085 406 EEPMDDLKSEAgE---TTASEMMFDDGIDEDI-NMAEVEKYRKERE-NAQWPDEVDTPMDMPARIAFQKYRGLKSFRTST 480 Caenorhabditis elegans 19074063 219 EDLRVSIDAGGtFfseAEEADGECDEESLMSAcDSDDPKENDEDDE--SALDDESSAGDQPSLIDKYSEYRGIRNLSTCS 296 Encephalitozoon cun... 17438157 238 EEECETMTTR------ESVHDDLSDEKVDEEA-EAKMLEKCKQERL-EEMFPGE-------------------------- 283 human 8922496 294 EEEYETMTIG------ESVHDDLYDKKVDEEA-EAKMLEKYKQERL-EEMFPDEVDTPRDVAARIRFQKYRGLKSFRTSP 365 human 19114303 427 EEKIDSDEEETiD---DAKSEMFVDLSEEEEVrQYEEYRKKQKELQeELEFPDEVELQPNELARERFKKYRGLRSLYTSQ 503 fission yeast 6320143 441 EEVAGDEEYD------IEDNEGFEELSPEEEErQLREFRDMEKEDR---EFPDEIELEPSESAIERLKRYRGLKNLYNCD 511 baker's yeast
7296422 519 WDAKE---NLPADYARIYQFQNFDRTKRRILN--EAKEFEGv------LPGLYVTLYVINVPESRWNAFKsaqLMDNIIV 587 fruit fly 17533085 481 WDPKE---NLPLDYARIFQFANYRNTKKNVMSkiGGNDVDAdsvadkkFNGAFASVFIENVPVAVLEAYK---DAKNLVL 554 Caenorhabditis elegans 19074063 297 FRSYS----FPEHYKSLVFFDDSRRAEKLVVGk--DSVMP---------DGQMVRIKLK-YEGLIEEQIY--------VV 352 Encephalitozoon cun... 17438157 -------------------------------------------------------------------------------- human 8922496 366 WDPKE---NLPQDYARIFQFQNFTNTRKSIFKevEEKEVEGa------EVGWYVTLHVSEVPVSVVECFR---QGTPLIA 433 human 19114303 504 WDADEydpNEPREWRQLFKFENYRNLKNKFLKqpFIGEAK---------PGKAVYVELRNVPIEIFEYYNk--PWNLLVL 572 fission yeast 6320143 512 WQVDEkdpSSPAEWKRLLRIGNYKNTKNRIIKe-tKNEAQA-------IAGDRIRMFIR-FPKFLLEKIQd-pKQLLFAV 581 baker's yeast
7296422 588 YGMLPHEHQMCVMNVVLQRMPDSEVPLKSKE--QLIIQCGYRRFVVNPIYS----QHTNGDKHKFERYFRPYETVCATFY 661 fruit fly 17533085 555 FQLLPHEHKMSVLNMVLKKHPSCTIPITSDQnqKFIFYVGFRQFEANAVFS----SNTPGDKFKLERFMPTEKTFVATVY 630 Caenorhabditis elegans 19074063 353 FGCYEYEDRKTIHNFHFEG----EVPLKEES---MVVDLGHKIVDICPMIT-------KNLNQKVFKRQKELESGVISFI 418 Encephalitozoon cun... 17438157 284 --------KMSVLNMVVRHDPGSTESAKAKE--ELIFRCRSRHFRASPLFS----QHAAADKHKFQRFLTADMALAVTVY 349 human 8922496 434 FSLLPHEQKMSVLNMVVRRDPGNTEPVKAKE--ELIFHCGFRRFRASPLFS----QHTAADKHKLQRFLTADMALVATVY 507 human 19114303 573 YSLLQYENKLTVSQFTAMQHSEYEEPIESKE--ELLLQIGPRRFMVRPLYSdptaSGASNNLQKYHRYLPPKQAVIASVI 650 fission yeast 6320143 582 YGLLLHEHKNAVVNFSLQRWEQYDKPVPSQE--PIVVQYGVRRYTIQPLFSq--gSNSPNNVHKYERFLHPDTVSVATCI 657 baker's yeast
7296422 662 APIQFPPAPVLAFKVNPDS--TLALVARGRLLSCNPDRIVLKRVVLSGHPMRINRKSASIRYMFFYKEDVEYFKPVKLRT 739 fruit fly 17533085 631 APITFNPATVLCFRQDDKG--RQELVATGSILDSNPDRIVLKRTVLAGHPYKINRRAVVVRYMFFNREDIEWFKPVELYT 708 Caenorhabditis elegans 19074063 419 GPISFGLSRVLIYRKSALRelSATTLASVGMNGFMGDRVIFEEAVLQGIPFKNKKRYSLVKRMFNSKEEVMYFRNIQIYM 498 Encephalitozoon cun... 17438157 350 APTTFPPSSLLLFKQKSNG--MHNLIATGHLLLVDPNRMVIKRVVLSDPPFKICTKMAVVCYMFFNREDVQWFKPVELRT 427 human 8922496 508 APITFPPASVLLFKQKSNG--MHSLIATGHLMSVDPDRMVIKRVVLSGHPFKIFTKMAVVRYMFFNREDVLWFKPVELRT 585 human 19114303 651 SPIVFGNVPIIMFKKSSDN--SLRLAATGSYVNCDTNSVIAKRAVLTGHPFKVHKKLVTIRYMFFNPEDVIWFKPIQLFT 728 fission yeast 6320143 658 APVDFTQSPAIFFKPSPTDakNIELIGHGTFLNADHSRILAKRAILTGHPFRFHKTVVTVRYMFFRPEDVEWFKSIPLFT 737 baker's yeast
7296422 740 K-CGRLGHIKESLGTHGHMKCYFDGQLRSYDTAFMYLYKRVFPKWTY---EECLVR 791 fruit fly 17533085 709 P-SGRRGHIKEAVGTHGNMKCRFDQQLNAQDSVMLNLYKRVFPVWNYsifNRSLNP 763 Caenorhabditis elegans 19074063 499 RnRKITGFIKKPIGTKGTFKGYFSQPIKSGDKVMMSLYKRVFLENQ---------- 544 Encephalitozoon cuniculi 17438157 428 K-WSRRGHIQEPSGTHGRMKCSFDRKLKSQNTELMNLYK----------------- 465 human 8922496 586 K-WGRRGHIKEPLGTHGHMKCSFDGKLKSQDTVLMNLYKRVFPKWTY---DPYVPE 637 human 19114303 729 K-QGRTGYIKEPLGTHGYFKATFNGKITVQDTVAMSLYKRMYPLPCElfkVTDIDS 783 fission yeast 6320143 738 K-SGRSGFIKESLGTHGYFKATFDGKLSAQDVVAMSLYKRMWPMPSLp--WNGM-- 788 baker's yeast
Jiyao W et al.(2023). "The conserved domain database in 2023.",