21281677   1 MCCTEgslRKRdsqrapeavlclqlwqrtvpldtlkglgtcfpsgpelRgagiaaAMERASERRTASALFAGFRALGLFS 80   human
7299761    1 MTHLRsedKPQ--------------------------------------------SEERKSVFKESSCIFRRNRALGYVS 36   fruit fly
4325344    1 ------------------------------------------------------------------MGIFEPFRAIGYIT 14   thale cress
17543478   1 -------------------------------------------------------------MKRIQSELFAPYRFLGVVT 19   Caenorhabditis ele...
19074287   1 -----------------------------------------------mGvgfpvpKICPLVMKNNESDLFKRYRVANQMA 33   Encephalitozoon cu...
3219965    1 MPFAE---KKR-------------------------------------R------TYENAVKPLRKSRIYAPFRSIGHVS 34   fission yeast
15214400   1 MSIDL---KKR-------------------------------------K------VEEDVRSRGKNSKIFSPFRIIGNVS 34   baker's yeast

21281677  81 NDIPh--vVRFSALKRRFYVTTCVGKSFHTYDVQKLSLVAVS-------NSVPQDICCMAADGRLVFAAYGNVFSAFARN 151  human
7299761   37 NQVPa--vTRYVQRRRDTLLITCIGRSFQVYTANHFRLLHVS-------GLHPDEITALATDRLHTYTASNKCIYAWRAG 107  fruit fly
4325344   15 STVP----FSVQRLGTETFVTVSVGKAFQIYNCAKLNLVIISkfflllkPKLPKKIRALASYRDYTFVAFGNEIAVFRRA 90   thale cress
17543478  20 GDVApsirSTFVAKKSALSVLCPIDNVIMQYNGKKLRAIGMS-------EPLSDKVSAVASSSTSVFAAHGTNITSLAFC 92   Caenorhabditis ele...
19074287  34 SGIP----LMVRDANGTVHITSATDTSYIVYDVRKMNVLFCG--------PMFNRIHCVHQRKDAVYVGSYRDVYVTTRG 101  Encephalitozoon cu...
3219965   35 NAVP----FDIEARGTHFLVTTSVGNTFQTYDCEKLNLLFVG-------KQLDKEITCLKSFKDFMLVAAGSKIFAYKRG 103  fission yeast
15214400  35 NGVP----FATGTLGSTFYIVTCVGKTFQIYDANTLHLLFVSe------KETPSSIVALSAHFHYVYAAYENKVGIYKRG 104  baker's yeast

21281677 152 KEIVHTFKGHK-AEIHFLQPFGDHIISVDTDGILIIWHIYS---EEE---YLQ-LTFDKSVFK--ISAILHPSTYLNKIL 221  human
7299761  108 KHIRHVYRGHQ-KDVHLLLPFGSSLIAIDRQNVLKVWNIST----EDv--YLE-VPFRSEEFQ--ITAVTHPPTYINKIV 177  fruit fly
4325344   91 -HQVATWSKHV-AKVDLLLVFGEHVLSLDVEGNMFIWAFKG---IEE---HLApIGNLQLTGKftPTSIVHPDTYLNKVL 162  thale cress
17543478  93 RDIKDSIDLGA--KIKIMTLIGTQLIAVDISSGIHVIDTSEg--------GLQmSLLMEGSDDfeITAICHPSTYLNKIV 162  Caenorhabditis ele...
19074287 102 DVVRCFTLPTGpAQSNKRVRVSEETMEGVIRQILGFGETILiltQNElfvTEDlSEIYKVEHDg-IERLFHPHTYINKVV 180  Encephalitozoon cu...
3219965  104 KIIWDIDVEQEhGTVTHLDAFGEWIIACTSSRHVYVWKHASk-ySVPe-lHT---TFLPNTNAd-ITSLLHPSTYLNKIL 177  fission yeast
15214400 105 -IEEHLLELETdANVEHLCIFGDYLCASTDDNSIFIYKKSDpqdKYPsefYTK-LTVTEIQGGe-IVSLQHLATYLNKLT 181  baker's yeast

21281677 222 LGSEQGSLQLWNVKSNKLLYTFPGWK-VGVTALQQAPAVDVVAIGLMSGQVIIHNIKFNETLMKFRQD-WGPITSISFRT 299  human
7299761  178 LGSQQGQLKILNIKKNSVVCTLSHHD-SRITCIEPSPALDVVAVGHGDGTIILLNLKFDEVLMSFQQD-WGQVTNLSFRT 255  fruit fly
4325344  163 VGSQEGPLQLWNINTKKMLYQFKGWG-SSVTSCVSSPALDVVAIGCADGKIHVHNIKLDEEIVTFEHAsRGAVTALSFST 241  thale cress
17543478 163 VGSSTGRMKIINFRTGKVIHEFQRSFdSRITIIEQTTALDVVVVGLENGEVMLFNVKMDKIITSFRHD--AKITNVAFRD 240  Caenorhabditis ele...
19074287 181 KVLKGGRMVLFNVSSRREIYVYRAFE-AMITAIEQSPVVDVVGIGLENGTVHIFNLRTDKILFSFKVD--GRVSELSFG- 256  Encephalitozoon cu...
3219965  178 LGFSDGALQIWNLRVSKRVHEFQEFFgDGITSLTQAPVLDVLAVGTISGRIVIFNLKNGSILMEFKQ--DGQVLSCSFRT 255  fission yeast
15214400 182 V-VTKSNVLLFNVRTGKLVFTSNEFP-DQITTAEPAPVLDIIALGTVTGEVIMFNMRKGKRIRTIKIP-QSRISSLSFRT 258  baker's yeast

21281677 300 DGHPVMAAGSPCGHIGLWDLEDKKLINQMRNAH---STAIAGLTFLHREPLLVTNGAD-NALRIWIFDg----pTGEG-- 369  human
7299761  256 DGPPILVSACSNGYMAFWNLEERKLAGQLQ-AH---EESVTTAICLPSEPVVFTTSPD-NSMRMFVFD------MPDGg- 323  fruit fly
4325344  242 DGRPLLASGGSFGVISIWNLNKKRLQSVIRDAH---DSSIISLNFLANEPVLMSASAD-NSLKMWIFD------TNDGd- 310  thale cress
17543478 241 DGESTMVTADKNGTMAVWDLENSPLHWITLCVS-------GFSTVQMECHVNLSAWKD-TRNHVPVSN------------ 300  Caenorhabditis ele...
19074287 257 -GNYLMAISRK-G-MFIFDLDGKKKIVAVENSA----GGPNGREECPGREVLSGRFLDgKSLVVSTKD------------ 317  Encephalitozoon cu...
3219965  256 DGTPILASSNPIGDLSFWDLSKRRIQNVTYNAH---FGSLPKIQFLNGQPILVTAGPD-NSLKEWIFD------SMDGa- 324  fission yeast
15214400 259 DGSSHLSVGTSSGDLIFYDLDRRSRIHVLKNIHresYGGVTQATFLNGQPIIVTSGGD-NSLKEYVFDpslsqgSGDVvv 337  baker's yeast

21281677 370 ---RLLRFRMGHSAPLTNIRYYGQNGQQILSASQDGTLQSFSTVHEKFNKSLGHgLINKKRVKRKGLQNTMSVRLPPITK 446  human
7299761  324 --aRQLRIREGHTKPPFCIRYHGSSGVSILSSGEDSTMRVFSTISESLNKSMGRaTYNPKATKKKNRFEHDKFGMPPILE 401  fruit fly
4325344  311 --pRLLRFRSGHSAPPLCIRFY-SNGRHILSAGQDRAFRLFSVIQEQQSRELSQ-RHISRRAKKLRLK-EEELKLKPVVS 385  thale cress
17543478 301 ---------------------LLEKITFCRPEKMDP-FRKYDVSSLTMRQKLGT----------VGQGVKLNKEVQNVAE 348  Caenorhabditis ele...
19074287 318 -------S----------LTVYEIQGYTLELIKRRRTYNDKIIGMEFIDEKNVL----LFG--PRNVFSMNMYKDEQNFM 374  Encephalitozoon cu...
3219965  325 --pRILRSRNGHYEPPSFVKFYGKSVHFLISAATDRSLRAVSLYQDSQSTELSQ-GSVISKAKKLNVR-PEELKLPEITA 400  fission yeast
15214400 338 qppRYLRSRGGHSQPPSYIAFADSQSHFMLSASKDRSLWSFSLRKDAQSQEMSQrLHKKQDGGRVGGS-TIKSKFPEIVA 416  baker's yeast

21281677 447 FAAEEARESDWDGIIACHQGKLSCSTWNYQKSTIGAYFLKPKELKK------------DDITATAVDITSCGNFAVIGLS 514  human
7299761  402 FTSDTAREKEWDNIAAIHAGVIQTTTWSFGKNRMGEHRLVPKQFQNsnr-------tnFQNETTCIVLTHCGNFVIIGYS 474  fruit fly
4325344  386 FDCAEIRERDWCNVVTCHMDTAEAYVWRLQNFVLGEHILKPCPENPtpikgvfvsrnhLLLAILACAISACGNFAVVGTA 465  thale cress
17543478 349 MAFGWQREAAWNNVFCRQVNDTKITTWQTRNNTSGAFTLEHDRFKKkv--------dfIDANATALCVSPCGNFVFIGYS 420  Caenorhabditis ele...
19074287 375 FKFKGDVEMMDVNKNIVCFGKRRLYALNFSEKNS-RFVLDKN------------------INCLAVYKDFC---CFG--- 429  Encephalitozoon cu...
3219965  401 LSSSNTREKYWDNVLTAHKNDSSARTWNWKSKTLGQHVLPTS----------------DGTSVRSVCVSCCGNFGLIGSS 464  fission yeast
15214400 417 LAIENARIGEWENIITAHKDEKFARTWDMRNKRVGRWTFDTT----------------DDGFVKSVAMSQCGNFGFIGSS 480  baker's yeast

21281677 515 SGTVDVYNMQSGIHRGSFG---------------------------KDQAHKGSVRGVAVDGLNQLTVTTGSEGLLKFWN 567  human
7299761  475 SGDIERFNIQSGLHRATYG----------------------------SPAHKMAVRGLASDNLNQTVISGCSEGLLKFWS 526  fruit fly
4325344  466 GGWIERFNLQSGISRGSYFdms----------------------ekRRYAHDGEVIGVACDSTNTLMISAGYHGDLKVWD 523  thale cress
17543478 421 TGHIDQFNAQSGRHVHSFTasttvkkskksknprkgptktngdihnDTPAADSPITSLSVDQRGKELMSTDAQGHILFWS 500  Caenorhabditis ele...
19074287 430 KDTITLMNLKSKLVHSRF-------------------------------DVSEELVDLAMDFTR--IVAATASGIHMYTT 476  Encephalitozoon cu...
3219965  465 KGVVDVYNMQSGIKRKSFG---------------------------QSSLSGKPVTAVMLDNVNRILVTASLDGILKFWD 517  fission yeast
15214400 481 NGSITIYNMQSGILRKKY------------------------------KLHKRAVTGISLDGMNRKMVSCGLDGIVGFYD 530  baker's yeast

21281677 568 FKNKI-----LIHSVSLSSSPNIMLLHRDSGILGLALDDFSISVLDIETRKIVREFSGHQGQINDMAFSPDGRWLISAAM 642  human
7299761  527 FKGKVd---kPLATLRLADGIALIRQHRESSMLAIGLETFKIFVVDMHTRVIVRKFVGHTAKLNDLTFSPDSRWLITAAM 603  fruit fly
4325344  524 FKKRE-----LKSQWDVGCSLVKIVYHRVNGLLATVADDFVIRLYDVVTLKMVREFRGHTDRITDLCFSEDGKWVISSSM 598  thale cress
17543478 501 LSTKAinakmFKKDVRLGICAPCPSNSLVALVAIAENGKESVILVDTVCHRVARAFETVGNKVNAMTFSSDGKWLLVADN 580  Caenorhabditis ele...
19074287 477 KGELV-----------SKHEQKGIVSIRLVESFVIICTLTQILFYDDG---VSRIFK-MGDEITDYSVSSDSKWIAILCK 541  Encephalitozoon cu...
3219965  518 FNKGN-----LIDSLDVGSSITHAIYQHSSDLVAVACDDFGIRIVDVQTRKIVRELWGHSNRLTSFDFSDTGRWLVTASL 592  fission yeast
15214400 531 FNKST-----LLGKLKLDAPITAMVYHRSSDLFALALDDLSIVVIDAVTQRVVRQLWGHSNRITAFDFSPEGRWIVSASL 605  baker's yeast

21281677 643 DCSIRTWDLPSGCLIDCFLLDSAPLNVSMSPTGDFLATSHVDHLGIYLWSNISLYSVV-SLRPLPADYVPSIVMLPG--- 718  human
7299761  604 DSTIKVWDIPSSYMVDHFRVEAPCVSLSMSPNGDFLATAHVGLLGIYLWANKTLFNQI-SLRSIDPLEPAPYVGLPTn-- 680  fruit fly
4325344  599 DGSLRIWDVILAKQIDGVHVDVPITALSLSPNMDVLATAHSDQNGVYLWVNQSMFSGLpSVESYASGKDVVNVKLPSvsa 678  thale cress
17543478 581 DSYIRVFDVATSQLIDVLLFSKPCISMSYNETGQYLATVHEGERAVYTWANKVLFVAHiNIRAHPADYLPSWSMISTeeg 660  Caenorhabditis ele...
19074287 542 -QKVFLYDILTMTLLDMLGLDDEAKFIRFSPNLDFLLVVSRD-NDLVLFSNKSNFQSS---------------VKPE--- 601  Encephalitozoon cu...
3219965  593 DGTIRTWDLPTGHLIDSISTPSVCTSLTFAPTGDYLATTHVDQVGISLWTNLSMFKHV-STKALRLDDV-VEVSAPS--- 667  fission yeast
15214400 606 DSTIRTWDLPTGGCIDGIIVDNVATNVKFSPNGDLLATTHVTGNGICIWTNRAQFKTV-STRTIDESEF-ARMALPS--- 680  baker's yeast

21281677 719 -TCQTQDVEVSEETV---EPS----DELI---EYDSPEQLNEQLVTLSLLPESRWKNLLNLDVIKKKNKPKEPPKVPKSA 787  human
7299761  681 -VCDAMELEDGMKELeidEEDesklGELVd-tKYETPTQLSEELITLSGLAASRWQNLLDLELIKQRNKPKAPPKAPKQA 758  fruit fly
4325344  679 lTSSEADDDMDRQVL---ENS-----EALqasSFSISQKQIPELVTLSLLPKSQWQSLINLDIIKARNKPIEPPKKPEKA 750  thale cress
17543478 661 gTCDIDDDEDDLTTL-----M----DQDI---KAMKELQIDENLVTFSGLPSSRWANLPDLALIKERNKPTDAVKKIKQA 728  Caenorhabditis ele...
19074287 602 -----------EVTL-----------------NFSEFEERNDALETVWK----RKRVSLHSELLLLRGLKSK-PEDTRAE 648  Encephalitozoon cu...
3219965  668 -VSGEKGISVVEAALn-vESNae-dEEDI---SYRTMDQLDPNLQTLSKLPRTQWQTLINLEAIKARNAPKEVPKVPEKA 741  fission yeast
15214400 681 -TSVRGNDSMLSGAL---ESNggedLNDIdfnTYTSLEQIDKELLTLSIGPRSKMNTLLHLDVIRKRSKPKEAPKKSEKL 756  baker's yeast

21281677 788 PFFIP----TIP---GLVPR---------------YAAPEQNNDPQQSKVVNLGVLAQKSDFCLKLEEGLVNNKYDTALN 845  human
7299761  759 PFFLP----TVS---GLELR---------------FDVENGQKEEDESRIRKASTLNNLTAFGQLLEETADSLDFASAVA 816  fruit fly
4325344  751 PFFLP----SIPslsGDILFkand--------seaDGENEENNKKDQNSMKNFDAL--ESPFSKHLKSSWDSKHFLDFTN 816  thale cress
17543478 729 PFFLS----ASAtldGFEFEt--------------ENIGDEMDGDSRYITSKRNLLELESSFTTLLRNAKTRDHLLDAFK 790  Caenorhabditis ele...
19074287 649 DSSLP--------------E---------------PSLEMLEKLLDEDWIKGLS-----K--EEALR----------VMD 682  Encephalitozoon cu...
3219965  742 PFFLPs--lKDQs-eATVPKq--------------PIATEISKPTAVASIKVSG-----TEFSTLLH-GN---DDDAFFE 795  fission yeast
15214400 757 PFFLQlsgeKVGd-eASVREgiahetpeeihrrdqEAQKKLDAEEQMNKFKVTGRLGFESHFTKQLREGSQSKDYSSLLA 835  baker's yeast

21281677 846 LLKESGPSGIETELRSLSp---DCGGSIEVMQSFLKMIGMMLD-------RKRDFELAQAYLALFLKLHLKML----P-S 910  human
7299761  817 HLTQLGPSMVDFEIKSLHp---EAGGTLLAMLQFLKLVKFMFG-------TNLNFELAQSYLSVFLRSHGLGLt---EfP 883  fruit fly
4325344  817 YMKSLSPSALDMELRMLEiideDVEEELIKRPEFI-LIGQLLDyfinevsCKNDFEFMQAVVKLFLKIHGETIrc-hP-- 892  thale cress
17543478 791 TLQNMSLSAIDFQIRTLN------PKTIP---IFFRMLLEVLK-------TKTNFELVQAYAATATKIHRTIMwnasEgA 854  Caenorhabditis ele...
19074287 683 LIIPHISTSMDVVQRIL-------------------------------------FSLLR------YKSHLLEP------- 712  Encephalitozoon cu...
3219965  796 YLKSLGPAKIDLEIRSL-----DAYPPYEEFILFINIMTRRLS-------KRRDFELVQACMSVFTKSHEDVLlm-hDtP 862  fission yeast
15214400 836 TLINFSPAAVDLEIRSL-----NSFEPFDEIVWFIDALTQGLK-------SNKNFELYETFMSLLFKAHGDVIha-nNkN 902  baker's yeast

21281677 911 EPv--LLEEITNLSSQVEENWTHLQSLFNQSMCILNYLKSALL 951  human
7299761  884 -D---LVKELRTVSQVQQEAWQRVEEKLIYGTGVVAALRNFAH 922  fruit fly
4325344  893 -S---LQEKAKKLLETQSLVWQKMEKLFQSTRCIVTFLSNSQF 931  thale cress
17543478 855 SEheeLTEVLEEMAQVQMESWNEMENLFVENMAVVQWIKNALL 897  Caenorhabditis elegans
19074287 713 -------EDIQIFNERFSREWDDFEENALKAMGYLEIEADGLL 748  Encephalitozoon cuniculi
3219965  863 EDtvpVFESLKAWESVHKEENQRLLDLVGYCSGILSFMRT--- 902  fission yeast
15214400 903 QD---IASALQNWEDVHKKED-RLDDLVKFCMGVAAFVTTA-- 939  baker's yeast