1F60_A 1 MGKEKSHINVVVIG------------------------HVDSGKSTTTGhliYKC------------------------- 31 baker's yeast 7302084 1 MGKEKIHINIVVIG------------------------HVDSGKSTTTGhliYKC------------------------- 31 fruit fly 7303554 1 MGKEKIHINIVVIG------------------------HVDSGKSTTTGhliYKC------------------------- 31 fruit fly 19074188 40 EDDSKPRLNACFIG------------------------HVDSGKSTTVG---MLSyq----------------------- 69 Encephalitozoon cun... 30149139 -------------------------------------------------------------------------------- human 17477080 -------------------------------------------------------------------------------- human 20539466 -------------------------------------------------------------------------------- human 22043347 -------------------------------------------------------------------------------- human 22064535 1 MAMQVERRSIPLDS------------------------EWHILCTECWLtsiG--------------------------- 29 human 30157651 43 QDPGTPRPKDSILLraisrglsppegqlkpaarirshlHAKCSSETERVgcrDFKphnrhvivlylliqsetcfivlpgg 122 human
1F60_A 32 --GGI----------------DKRTIEK---FEKEAA----------------------ELGKGSFKYA-WVLDKLKAER 67 baker's yeast 7302084 32 --GGI----------------DKRTIEK---FEKEAQ----------------------EMGKGSFKYA-WVLDKLKAER 67 fruit fly 7303554 32 --GGI----------------DKRTIEK---FEKEAQ----------------------EMGKGSFKYA-WVLDKLKAER 67 fruit fly 19074188 70 -lGAV----------------DKREMEK---YEKEAA----------------------LNNKETFYLA-YLTDKTDAER 106 Encephalitozoon cun... 30149139 1 -----------------------------------------------------------------------MSEKSFLGM 9 human 17477080 1 -------------------------------------------------------------------------------M 1 human 20539466 -------------------------------------------------------------------------------- human 22043347 -------------------------------------------------------------------------------- human 22064535 30 ----L----------------SGLNAST---ACKMSA----------------------TQAPGFVIASkGRTLNCHYIP 64 human 30157651 123 rgGALihadnswnfdrlpsteDSSYSSKptaMSKEKAfiniiiighvdsgkstttgpltNVGEGSFKYA-WVLDKLRAER 201 human
1F60_A 68 ERG-IT---IDIALWKFETPKYQVTVIDAPGHRDFIKNMITG----------TSQADCAILIIAG----GVGEFEAGISK 129 baker's yeast 7302084 68 ERG-IT---IDIALWKFETSKYYVTIIDAPGHRDFIKNMITG----------TSQADCAVLIVAA----GTGEFEAGISK 129 fruit fly 7303554 68 ERG-IT---IDIALWKFETAKYYVTIIDAPGHRDFIKNMITG----------TSQADCAVLIVAA----GTGEFEAGISK 129 fruit fly 19074188 107 KRGi----tITTTLVNLPTEKFNINILDCPGHKDFVKNMVTG----------ASQADVAVVIVPA------SGFESCVGV 166 Encephalitozoon cun... 30149139 10 GVLpEHryhENHSKKPKWERKNILVNIVIIGHIDSGKSTTTGhliskcggvdKRMADCAVLIVAAg----VGEFEAGVSK 85 human 17477080 2 DLLlEHkchEKHGLKAKRGKEKTPTNIDVIGHLGSGKSTTTGhliy---rcggMVAGCAVLIVAAg----IGEFEASISK 74 human 20539466 -------------------------------------------------------------------------------- human 22043347 1 ---mNVvssLVSLLWKFETSKYYVTIIDAPGHRDVIKNMITgt----------sQADRAVLIVAAg----VGEFEAGISK 63 human 22064535 65 NLEdIRkedIESEALLGSIHLGMMLVSDVTLSTVSKLESTGV----------IIYSNLGQSTTAGhliyICGGTDKRNIE 134 human 30157651 202 ERRi----tIDISLWKFKTSTYYSIIIDAPGHRDFIMTMIRG----------TSQADCAVLFVAG------GWAEAGIFK 261 human
1F60_A 130 DGQTREHALLAFTLGVRQLIVAVNKMDSVK--WDESRFQEI-VKETSNFIKKVGYNPKTVpfvpisgwngdnmieattna 206 baker's yeast 7302084 130 NGQTREHALLAFTLGVKQLIVGVNKMDSTEppYSEARYEEI-KKEVSSYIKKIGYNPASV-------------------- 188 fruit fly 7303554 130 NGQTREHALLAFTLGVKQLIVGVNKMDSSEppYSEARYEEI-KKEVSSYIKKIGYNPAAV-------------------- 188 fruit fly 19074188 167 GGMLKTHIMISGILGCEKLIVCVNKMDEIPenKRMEKFNEVsAEMLRIVKRSHKDKNPIIipisaf-------------- 232 Encephalitozoon cun... 30149139 86 NEQTHEYALLTYTLGVKQLIVGV-KMDSTEppYSQKRHKEV-IKKISTHIKKIDYNPYplniafvpis------------ 151 human 17477080 75 NGQIQEHALLAYTLGVKQQILGVSKIDSTEplYSQKRYKEI-VKEISTFLKKIGYNldtvafvsis-------------- 139 human 20539466 1 -------------------------MDSTEspYSQKRHEGI-IKEVSMYITKIGYNPD---------------------- 32 human 22043347 64 NGQTREHALLAYTLGVKQPIVGVNKMVTLShpIARRDTRKS-LRKSALH------------------------------- 111 human 22064535 135 KAEKETAEMEKGSFK----YAWVLDKLKAEreHTASTSSNC-KPLCCLSKMSLKLAIS---------------------- 187 human 30157651 262 NPQTHELALLANWRDVTQLIVIFNEIDSTEpaYSGSRLQVItKEGQPGWR--RADHTPDSppl----------------- 322 human
1F60_A 207 pwykgweketkagvvkgktlleaidaieqpsrptdkplrlpLQDVYKIGGIGtvp--vgrVETGVIKPGMVVTFAPAGV- 283 baker's yeast 7302084 189 ------------------------------------------------------------AFVPISGWHGDNMLEPSEK- 207 fruit fly 7303554 189 ------------------------------------------------------------AFVPISGWHGDNMLEPSTN- 207 fruit fly 19074188 233 -----------------------------------kginltKKGEKFEWFKGwkekegssVIYTLEEALNYQDVPERHNd 277 Encephalitozoon cun... 30149139 152 -------------------------------vwncdsmlvpRVHMPGLKGWKvtrndgndSGTMLPEALNYILPPAHPTd 200 human 17477080 140 -------------------------------gwnggsmlkpSAHRPWFKGWKvvrkdgnaSGTTLPEALDCVLSLTCPTv 188 human 20539466 33 -----------------------------------------TVACAPLSGWN--------------------------Vd 45 human 22043347 -------------------------------------------------------------------------------- human 22064535 188 -----------------------------------------VLSLIVVTFAS--------------------------Vn 200 human 30157651 323 --------------------------------------dipKMPWFKCWKVEwkeg--namgVTLLEALNSILPTTRRVd 362 human
1F60_A 284 -TTEVKSVEMHHEQLE--------QGVPGDNVGFNVKNVSVKEIR----RGN-------VCGDAKND----------PPK 333 baker's yeast 7302084 208 -MPWFKGWSVERKEGK--------AEGKCLIDALDAILPPQRPTD----KP----------------------------- 245 fruit fly 7303554 208 -MPWFKGWKVERKEGN--------ADGKTLIDALDAILPPARPTD----KA----------------------------- 245 fruit fly 19074188 278 kPLRMPITKVCSIAG-----------VGKIFTGRVEYGTITPNLKitiqPAG-------VVGETRSVeihnkprsmiPCG 339 Encephalitozoon cun... 30149139 201 kSLRLPLQDVYNIGd--------iG---TVSMGWAETGVLKPGTVvtfaPVNvttegksVEMHHEALsealpgdnvgFDV 269 human 17477080 189 rPLHLPLQDVYRLGGTdtifvgrvGGTDTIFVGRAKPGFLKPGMVvtfaPVNiat--kdVLKCTMKL------------- 253 human 20539466 46 vTTEVKSVEMHHEASSe--------aLPGDNVGLNAKNISVKNVC----HGN-------VAGDSKND----------PSV 96 human 22043347 -------------------------------------------------------------------------------- human 22064535 201 vKTEVKSIEMHHEAPSe--------dLPGDNVGFNVKNMPVEDVH----CGN-------VAGDSKND----------PPV 251 human 30157651 363 nPLRLPLQDVYKMGGDpgl--sgaEGIGSVPVGRVEGGFFKFGIVvtfaPSN-------VTTKVKSVemhhevlaeaLWL 433 human
1F60_A 334 GCASFN---------------------------------ATVIVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRR 380 baker's yeast 7302084 246 ---------------------------------------------LRLPLQDVYKIGGIGTVPVGRVETGLLKPGMVVNF 280 fruit fly 7303554 246 ---------------------------------------------LRLPLQDVYKIGGIGTVPVGRVETGVLKPGTVVVF 280 fruit fly 19074188 340 ENCGVAlkggvigeidkvdaghvisandenkavaypgakIRTIVVGRPKGLSPGYTPQINFGNCHSPGRIAKILSKV--V 417 Encephalitozoon cun... 30149139 270 KNVSVKdvrcgnvagdsi----------ndppveavdftAQVIILNHPGHISTDCGPVLNCQTAHIACKFAELKKKTDCC 339 human 17477080 -------------------------------------------------------------------------------- human 20539466 97 GATSFT---------------------------------GQVIILHHPDQINGGYAAILDCHTVHIACSFAELRGKIDHH 143 human 22043347 -------------------------------------------------------------------------------- human 22064535 252 ETAGLT---------------------------------AQVIILNQPGQISAHCESVLDCHTTQIACKVAELKEKIDCN 298 human 30157651 434 TM------------------------------------------------------------------------------ 435 human
1F60_A 381 S----------GKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGRFAVRDMRQTVAVGVIKSVDKTEK-AAKVT 449 baker's yeast 7302084 281 A----------PVNLVTEVKSVEMHHEALTEAMPGDNVGFNVKNVSVKELRRGYVAGDSKNNPPRGAADFTAQViVLNHP 350 fruit fly 7303554 281 A----------PANITTEVKSVEMHHEALQEAVPGDNVGFNVKNVSVKELRRGYVAGDSKANPPKGAADFTAQViVLNHP 350 fruit fly 19074188 418 G----------KEVHENPENVANGENFTG-IVVFQKPLVIDKMERFQNLAKFALMDSNGVVGIGNVMEPLTRDQlLKDYG 486 Encephalitozoon cun... 30149139 340 SvllpfvgfikAVDKKGAGAGKVTKPAQKarkak---------------------------------------------- 373 human 17477080 -------------------------------------------------------------------------------- human 20539466 144 S----------DTVEDGGSPQGGAPESSSSSSRPSSSATRQSPPSAVPSPGPPSRQLSEEGAQDGEEVQIYIINtAGQED 213 human 22043347 -------------------------------------------------------------------------------- human 22064535 299 S----------GKKLEDDPKLLNADDAAILYMVPGKPISGQGKVIKGVIKAVDKKARYCQGAG-------KVCKsAQKAQ 361 human 30157651 -------------------------------------------------------------------------------- human
1F60_A 450 KAAQKAAKK 458 baker's yeast 7302084 351 GQIANGYTP 359 fruit fly 7303554 351 GQIANGYTP 359 fruit fly 19074188 487 IDLNEDPKA 495 Encephalitozoon cuniculi 30149139 --------- human 17477080 --------- human 20539466 214 YTAIKDNYF 222 human 22043347 --------- human 22064535 362 KAKQMLSLI 370 human 30157651 --------- human
Jiyao W et al.(2023). "The conserved domain database in 2023.",