Conserved Protein Domain Family
Hia
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COG5295: Hia (This model is not part of the current CDD release)
Type Vc autotransporter adhesin, Ata/Hia family [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures]
Type Vc autotransporter adhesin, Ata/Hia family; is part of the Pathway/BioSystem: Type V secretion system
Links
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Statistics
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PSSM-Id: 512742
Aligned: 276 rows
Threshold Bit Score: 36.3437
Created: 24-Mar-2025
Updated: 26-Mar-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_071193745    1 MKTTFSKIALIVVGVICFSAHAANTKDPSQTRLTFFGDGNVSTFSGPWASYGCTSPDSVSDIYGSYNTVNNLSCSEIMGS 80  
WP_012537331      --------------------------------------------------------------------------------     
WP_231951970  491 RVNVDQINGGTGNISRVNADQIVGGTGNISNVNADLLVAGTGNISNVNTDLLVAGTGNIARVNTDQIIAGSSEIARIDSN 570 
WP_014994499  379 GLSSIAMGDGATASGAQSISIGTGNTVSGDGSGAIGDPTTITGAGSYSVGNDNTIDADEAGVFGNRNILAATATGSRIIG 458 
WP_240313749 1185 VQNSESISKLTTDISEGVVGLVQQNSPIATITVAAMKGGEQISFAGQSGSRILTRVKRGALSTTSTDAINGSQLLTTNNE 1264
WP_164028189  132 YYGYPSSGGAIAVGLESHTIGNGAIAMGNKAQASGVKSIAIGNDARTLDITNTDGAANIDQNLKNNIKNTVDTLRKQNSP 211 
WP_049753187  520 VKLTEETKRKIDKIDNLGWKLKIAKGMGGEATNPPAEQLIKMDQTVTFTAGKNIKLEQNNGNITISTIGKLIAKTEWKDG 599 
WP_049753206  463 KIDKIDNLGWKLAITQGAGGQVTPTEHLIKMSDTATVTFTAGNNIKLEQNSGNITISTIGKLIEKTEWKNGNLQITYTDG 542 
WP_015431743 2381 LINPAETVKFIAGDNMVLTQDGNNFTYSVSHNPVFNGTVTAKEGITIGEGDNAVNMTPTTTVTTNGTTPATPAIDMNGAQ 2460
WP_011055729      --------------------------------------------------------------------------------     

WP_071193745   81 ANVVNSGDVNVMGQNNQLANTYANVFGDNNNTKNGNINAFGSGITIDGSGNGAFGFTINATGTNNITLGNELRTTGISTN 160 
WP_012537331      --------------------------------------------------------------------------------     
WP_231951970  571 VMNANQAIATTSLGVTNGPELTAAGIDAADKVISNVTAGTNSTDAVNKAQLDEKADKSTAYTFNVSNNEAALSSDALADT 650 
WP_014994499  459 NDNDVDVADAFVIGNGADVTVAEGVALGNGSLSDTGAGVAGYNPTTSAADGLDAGIAATLSTTGAVAVGDAGTGVFRQIT 538 
WP_240313749 1265 VEKNADGIEQLREEIMNGSIGLLLDNPKHGGWSTDSNSTRKTRSITLAAGHVAEEVSIEGKNGERRLIGVAPGELSPTSV 1344
WP_164028189  212 VGMEAELVGLSDEATSTIAIGDESRAIGWGSTALGTKAYALNDRATTLGDDSKTLGYAGTSVGTHAYSFGKGASALGTWA 291 
WP_049753187  600 DLLITYTDGKTDTIAKGKDGKNGEKGDRGEQGPAGPRGEAGPKGEAGPKGEAGPKGEAGPVGPAGPTGPAGAAGPKGEKG 679 
WP_049753206  543 SYDTIAKGKDGKNGEKGDRGEQGPAGPRGEAGPRGEAGPKGEAGPAGPVGPRGEPGQAGPAGPRGPQGTAGAQGPKGDKG 622 
WP_015431743 2461 LTNLSHNLPTEGVTAGDISPVVNQNNAATVQDVLNAGWNLQENGNAKDFVRPYDTVNFANGSGTTVKIDSDGKVSTVKVN 2540
WP_011055729    1 -----------------------------------MGPITSPNCNTPSIGIINTNAGQLFVGGTGAAVSGTLGPTFWTGT 45  

WP_071193745  161 LTGSYITSSGNYNNIFGYSSSVQSDGINAIGNGNTVVEATSSNIFGSNNTVKDLSATSFSSSADGTSITGNSNTVSAGSN 240 
WP_012537331    1 ---------------------------------------mstfrkkilfvavsgtfaismagggtadastvqggvglvaa 41  
WP_231951970  651 WTLEQGDSLTFGATSDLNVTTDGQGKVVYGLSDEVKSKIDTAAAANKGVNVSTKAADGKVTTHNVKSGETVAVHSGKNIA 730 
WP_014994499  539 GVAAGSEDSDAVNVAQLKASETHYYSVNDNNMISGNYANDGATGVNALAAGVDTAASGTSSVAVGDAATAYNAGGIAVGL 618 
WP_240313749 1345 DAVNGSQLLKTNNELMQNANNIAAIANSFGGGAMIDPTEDKFVSPSYIVQNREVNNVGDALSMLNDVVVLNSSDIAALKA 1424
WP_164028189  292 EALGDYSTSAGPSSSAAGDNSIAMGNGAAASGLNAIAIGSMTTDTKAWYTTGGGKQVHRSEHEVWNAVGDHSIALGTDSQ 371 
WP_049753187  680 DPGPKGEAGSTGPTGPAGPKGDPGQAGPAGPRGPAGPKGDAGPKGDTGQRGETGPAGPAGPKGEPGPKGEQGIPGPAGPA 759 
WP_049753206  623 DPGQAGPAGPRGPAGPAGPKGDTGQKGETGPAGPAGPRGEAGPAGATGPQGPQGTAGAQGPKGDKGEPGQAGPAGPRGPQ 702 
WP_015431743 2541 VNTENSDTINLAVNPATGNIAATAVTAPLDMNSNGTVVVPANQNALVSAADVAKAINGSGFDLDIDAAPNTNGKVVANDE 2620
WP_011055729   46 FATPVGTSNTATAYGMVVQSGGAYITGNTYVQGGLFLNGQKATNLAPATISSTSTDAVVGSQLYNLVQDGTRYFHANSVN 125 

WP_071193745  241 SAILGNNNTITGGEHDSGGILIGFGSQMSYADDAIGIGTTTTvkdansiaigqnanasngavai---------------- 304 
WP_012537331   42 ltqtlglgsavtqygdsnniasgpgsaagtndtavgvnatstgtnsvalgynssdggqnnvvavgsatqqrkiinvapgt 121 
WP_231951970  731 ITQNANTITVATIDNPTFAKVTADSVSVKNGPTIDSNGINMNnk------------------------------------ 774 
WP_014994499  619 NAVAGVDGSATIANDIAQGANATATGGNTVALGSNATATGADsvslgsnssasgatstalgyatqasntdttavgngaqa 698 
WP_240313749 1425 GRNKYPSNTMTQLVREDASSKKITVGKLTGGKSVDITGTEGVr------------------------------------- 1467
WP_164028189  372 ATKDNAIAMGKEAFADHDRSVALGDQSATENAKDTSQGTVNGitygnfagstsvgtvsvgnsklgetrqiknvsagdisp 451 
WP_049753187  760 GPKGDKGDTGPAGPQGPAGPTGPQGPAGPTGSQDPAGPTGNSelkgitsiangndatkangakitlsagstnktvnvnda 839 
WP_049753206  703 GTAGAQGPKGDKGEPGQAGPTGPQGPTGPTGSQDPAGPTGNSelkgitsiangndatkangakitlsagstdktvnvnda 782 
WP_015431743 2621 KAARVNPGAKVAINAGRNIEISRSGNEITVATTENPVFDSVTansvklgdtgpqisaa---------------------- 2678
WP_011055729  126 PTDSLASGLETIAVGPATVVSGDNGVGIGNTALVGAAATGGIaigfgtqvtaagataigsaaqaqgaqslalgagavtsq 205 

WP_071193745      --------------------------------------------------------------------------------     
WP_012537331  122 lsqtstdavngsqlyatdqqqltntsnisnlqnqqkidqtnishlqstvsnisnltsvagdltaikqqqqtdmsniavnt 201 
WP_231951970      --------------------------------------------------------------------------------     
WP_014994499  699 tgaqdtalgvtalasggnstavgnqaasagsnatavgatasasggqasafglgatasnvnatalgvgtqatsfastavgn 778 
WP_240313749      --------------------------------------------------------------------------------     
WP_164028189  452 tstdaingsqlyfianklteemknsqpkpipvpptvnvdtgdisvndngivvadstkg---------------------- 509 
WP_049753187  840 kitnvaagtadtdavnvsqlntkaaa------------------------------------------------------ 865 
WP_049753206  783 kitnvaagvadtdavnvsqlntkaaa------------------------------------------------------ 808 
WP_015431743      --------------------------------------------------------------------------------     
WP_011055729  206 ansialgaasintvgaqssysayaltapqasvgelgigtalgnrkitgvaagsassdavnvaqltavgdqvqqntanits 285 

WP_071193745      --------------------------------------------------------------------------------     
WP_012537331  202 sdisnlkgqqgtdvtnisnlqkqqatdvsnianntsniasntsniavntsdisnlkgqqgtdvtnisnlqkqqatdvsni 281 
WP_231951970      --------------------------------------------------------------------------------     
WP_014994499  779 qstatgqssvavgdvaqasgtnaiaigtgavasaedsisigtgnqvsgigsgaigdpttitgsgsysvgnnniidadeag 858 
WP_240313749      --------------------------------------------------------------------------------     
WP_164028189      --------------------------------------------------------------------------------     
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WP_049753206      --------------------------------------------------------------------------------     
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WP_011055729  286 lggrvttiegsmasiangggvkyfhanstqpdsvasgtnsvaigpaslasgnaalasg---------------------- 343 

WP_071193745      --------------------------------------------------------------------------------     
WP_012537331  282 anntsnisnlsnvvggltstavdltkikkqqatdvtniasntsniasntsdisnlknqqgtdvtnisnlqkqqatdvsni 361 
WP_231951970      --------------------------------------------------------------------------------     
WP_014994499  859 vfgndnilaatatgsriigngndvdvadafvigngadvtvaegvalgngaiadtgagiqgynpttgaadgldagiaatls 938 
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WP_164028189      --------------------------------------------------------------------------------     
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WP_015431743      --------------------------------------------------------------------------------     
WP_011055729      --------------------------------------------------------------------------------     

WP_071193745      --------------------------------------------------------------------------------     
WP_012537331  362 agnttniasntsdisnlknqqgtdvtnisnlqkqqatdvsniagnttniasntsdisnlknqqgtdvtniasntkdikni 441 
WP_231951970      --------------------------------------------------------------------------------     
WP_014994499  939 ttgavavgdagtgvfrqitgvaagtedsdavnvaqlkasethyysvndngviggnyandgatginalaagvdasaagdgg 1018
WP_240313749      --------------------------------------------------------------------------------     
WP_164028189      --------------------------------------------------------------------------------     
WP_049753187      --------------------------------------------------------------------------------     
WP_049753206      --------------------------------------------------------------------------------     
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WP_071193745      --------------------------------------------------------------------------------     
WP_012537331  442 ktqqatdvsniasnttniasntsdisnlktqqgtdvtniasntndiknvktqqatdvsniamntsnisqlqtivngkvat 521 
WP_231951970      --------------------------------------------------------------------------------     
WP_014994499 1019 vatgnnasavddnsvaigtsatanggntdfgavavgnmatatgdgatalgsetlaladgatavgddanalalfstalgdg 1098
WP_240313749      --------------------------------------------------------------------------------     
WP_164028189      --------------------------------------------------------------------------------     
WP_049753187      --------------------------------------------------------------------------------     
WP_049753206      --------------------------------------------------------------------------------     
WP_015431743      --------------------------------------------------------------------------------     
WP_011055729  344 ---------------------agavaigdgaaasadgsvaigqgsgdngrgvenyigkysnasntssgtvsvgntatget 402 

WP_071193745      --------------------------------------------------------------------------------     
WP_012537331  522 cqvvngglqctyaqakgtndvaagngalangtssiaigtnatatyngavaigdgaravadpataiganaqanannstaig 601 
WP_231951970      --------------------------------------------------------------------------------     
WP_014994499 1099 aevdaasisgvaigaeatasgaplgtavgtlatasalqatavgtgaaasgsqsaafgagaqatvaegvalgtgsiaataa 1178
WP_240313749      --------------------------------------------------------------------------------     
WP_164028189  510 ---------------------nlasvtdvanainnssfnittgsedggkainvtiekvkagntvaykagknmvvkqdgqn 568 
WP_049753187  866 -----------------------------------------------------skteveagknvkvtsktgangqnihnv 892 
WP_049753206  809 -----------------------------------------------------arteveagknvkvtsktgangqniynv 835 
WP_015431743      --------------------------------------------------------------------------------     
WP_011055729  403 rtvsnvadglqatdavnlrqldgiaasivvvennvsglqngtdgmfqvnnssglakpsatgansatggagsvasgnnsta 482 

WP_071193745  305 ---------------gynsvgsragsvsfgstgnerqLTNVATGTADTDAVNVKQLHDaatvalstansytdtretaint 369 
WP_012537331  602 anstanginsvalgqgstanransvsvgnastgltrqITNVAPGTTPNDVATVGQLQG---------------------- 659 
WP_231951970  775 ------------------------------------rITNVADGVEAGDAVNVRQLn----------------------- 795 
WP_014994499 1179 gvagydpltglpstdtsstwtstmgavsvggagetrqITNVAAGTNDTDAVNVAQLQA---------------------- 1236
WP_240313749 1468 ------------------------------------rISGVKAGVADNDAVNLEQLNK---------------------- 1489
WP_164028189  569 itysttdkpifdvvnanefkagdvvvnnqginagnkkITNVAEGTRDSDAVNYAQLRKt--------------------- 627 
WP_049753187  893 svsgdlsditsisngdtkvslgkdqkgnpvvnmngarITNVGDGSAEGDIVNVRQLNK---------------------- 950 
WP_049753206  836 svsgdlsditsisngdtkvslgkdqkgnpvvnmngarITNVGDGSAEGDIVNVRQLNK---------------------- 893 
WP_015431743 2679 ----------------------gdtvkvakadgsaarITNVAPGVDPTDAVNVSQL------------------------ 2712
WP_011055729  483 fgsgakataansaalgansvadransvsvgsvgnerqITNVAPATQGTDAVNFDQLKS---------------------- 540 

WP_071193745  370 rtdglmateqqarqsgntatlnsansytdtreaainqrtdslmateqqarqngntatlnsansytdtreaainqrtdslm 449 
WP_012537331      --------------------------------------------------------------------------------     
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WP_014994499      --------------------------------------------------------------------------------     
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WP_164028189      --------------------------------------------------------------------------------     
WP_049753187      --------------------------------------------------------------------------------     
WP_049753206      --------------------------------------------------------------------------------     
WP_015431743      --------------------------------------------------------------------------------     
WP_011055729      --------------------------------------------------------------------------------     

WP_071193745  450 ateqqarqsgntatlnsatsytdtretainqrtdtllateqqarqsssvstlnsatgytdireeaintrtdsllttelqa 529 
WP_012537331      --------------------------------------------------------------------------------     
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WP_014994499      --------------------------------------------------------------------------------     
WP_240313749      --------------------------------------------------------------------------------     
WP_164028189      --------------------------------------------------------------------------------     
WP_049753187      --------------------------------------------------------------------------------     
WP_049753206      --------------------------------------------------------------------------------     
WP_015431743      --------------------------------------------------------------------------------     
WP_011055729      --------------------------------------------------------------------------------     

WP_071193745  530 rqagdaatlnsakgytdareqvinsrvdtllaqeksdritgdadnlaksgnyndqqtavaistansytdareqainartd 609 
WP_012537331      --------------------------------------------------------------------------------     
WP_231951970      --------------------------------------------------------------------------------     
WP_014994499      --------------------------------------------------------------------------------     
WP_240313749      --------------------------------------------------------------------------------     
WP_164028189      --------------------------------------------------------------------------------     
WP_049753187      --------------------------------------------------------------------------------     
WP_049753206      --------------------------------------------------------------------------------     
WP_015431743      --------------------------------------------------------------------------------     
WP_011055729      --------------------------------------------------------------------------------     

WP_071193745  610 glvadeksqriagdaetlsaantytdtresainqrtdtlmateqlarqngdaatlnsaksytdnretainqrtdgmmaae 689 
WP_012537331      --------------------------------------------------------------------------------     
WP_231951970      --------------------------------------------------------------------------------     
WP_014994499      --------------------------------------------------------------------------------     
WP_240313749      --------------------------------------------------------------------------------     
WP_164028189      --------------------------------------------------------------------------------     
WP_049753187      --------------------------------------------------------------------------------     
WP_049753206      --------------------------------------------------------------------------------     
WP_015431743      --------------------------------------------------------------------------------     
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WP_071193745  690 qqardagdaatlgsaksytdtretainqrtdglmaterqardagdaatlgsaksytdtretaINqrtdglmaaeqqarqn 769 
WP_012537331      --------------------------------------------------------------------------------     
WP_231951970      --------------------------------------------------------------------------------     
WP_014994499 1237 --------------------------------------------------------------SE---------------- 1238
WP_240313749 1490 --------------------------------------------------------------TL---------------- 1491
WP_164028189      --------------------------------------------------------------------------------     
WP_049753187  951 --------------------------------------------------------------VV---------------- 952 
WP_049753206  894 --------------------------------------------------------------VV---------------- 895 
WP_015431743      --------------------------------------------------------------------------------     
WP_011055729  541 --------------------------------------------------------------IS---------------- 542 

WP_071193745  770 gdaatlnsaksytdtretvinqrtdgliaseqqaresgdARTlsgarsytdtretainkrtdkmmdteqlariegdrqtl 849 
WP_012537331      --------------------------------------------------------------------------------     
WP_231951970      --------------------------------------------------------------------------------     
WP_014994499 1239 ---------------------------------------THy-------------------------------------- 1241
WP_240313749 1492 ---------------------------------------ADMrsand--------------------------------- 1499
WP_164028189      --------------------------------------------------------------------------------     
WP_049753187  953 ---------------------------------------SSVn------------------------------------- 956 
WP_049753206  896 ---------------------------------------SSVn------------------------------------- 899 
WP_015431743      --------------------------------------------------------------------------------     
WP_011055729  543 ---------------------------------------NQTnay----------------------------------- 548 

WP_071193745  850 gsakaytdqretainsrtdslvasehdariagdantlasagnytnQRFSE---LNDRVNRNERRANAGIAGVMAL-TNIP 925 
WP_012537331  660 ----------------------------------------------AVGQ---AQHYAAQ------VGSVNAAALnAAAS 684 
WP_231951970  796 ---------------------------------------------QTRND---FDKRLNRLNKDRKAGTASAIAT-AGLL 826 
WP_014994499 1242 ---------------------------------------------ySVNDngvVQGNYAN------DGATGVNAL-AAGT 1269
WP_240313749 1500 -----------------------------------------hsvnRAIKK---LDNRLDQVKNKLTAGIASSMAM-AGIP 1534
WP_164028189  628 --------------------------------------------nNQVRQ---LENKLNRVDRKLRGGIAQAGAM-ANIP 659 
WP_049753187  957 ---------------------------------------------TGFNQ---LSRDIGRVDVNARAGIASAGAM-ANLP 987 
WP_049753206  900 ---------------------------------------------TGFNQ---LSRDIGRVDVNARAGIASAGAM-ANLP 930 
WP_015431743 2713 ------------------------------------------------NQ---VKGDLRKQDKRRKAGHASSAAS-ASLM 2740
WP_011055729  549 -------------------------------------------tnQRYSE---LKQDLRKQNSVLSAGIASAMSM-ASLT 581 

WP_071193745  926 YLTKDVDNSFGMAIGSYRGETA---IAGGIQRqLSPR--VNARVSLTWDS----SQAVGVAGGL---------AVGW 984 
WP_012537331  685 AASGQGPNTVAGGYGEYDGQSA---FAFTYQHrFNCNwqALL--TVGSNGs---GKNTEVGAGA---------SYSW 744 
WP_231951970  827 QA-PAGQSGVTAAVGQYESQSA---VAVGYSQ-SLPSg-VGVKVSFSANT----RKELGGSVGM---------GYFW 884 
WP_014994499 1270 NALATGESTVAMGNGAe--aTAirdVMIG-------Dg-------aGANAgvggRDNIAIG-GLagqgrgdngSFNv 1329
WP_240313749 1535 QAYVPDSSLLGAAVASYRGGSA---IAIGVST-VSESgkWITKLQSSNNT----QKDFGVSLGI---------GYQW 1594
WP_164028189  660 QVTRNGASGVGVGVASYRDENA---ISVGYSL-MSDNgkHIIKTSVGLDT----RGYNMVGAGY---------MYQW 719 
WP_049753187  988 QISLPGKSAISVSNAQYRGQSA---YAIGYSR-ISDNgkWLIRASVSSNT----QRDTMIGGGV---------GFVW 1047
WP_049753206  931 QISLPGKSAISVSNAQYRGQSA---YAIGYSR-ISDNgkWLIRASVSSNT----QRDTMIGGGV---------GFVW 990 
WP_015431743 2741 QAYREGQSVVTAGVGQYQGQSG---LAVGYSR-ISDNgkVGVKLHLGANT----QKELSAGASV---------GYFW 2800
WP_011055729  582 QPYTSGSSMTTIGAASYRGQSA---LSLGVSS-ISDSgrWVSKLQASSNT----QGDFGIGVGV---------GYQW 641
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