Conserved Protein Domain Family
POL12

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COG5214: POL12 
DNA polymerase alpha-primase complex, polymerase-associated subunit B [DNA replication, recombination, and repair]
Statistics
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PSSM-Id: 227539
Aligned: 3 rows
Threshold Bit Score: 634.325
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
585063     9 THFgPdADKPEIITALENLTKLHALSVEDLYIKWEQFSNQRRQT-HTDLTSknIDEFKQFLQLQMEKranQISSSSKVNt 87  baker's yeast
19074717     --------------------------------------------------------------------------------     Encephalitozoon cun...
6015008    1 MEF-P-IDDEELLDERNKLLQICNMDEQTMFYKWESWCLQRGNTpKLDLDT--FKAFAKDMKFQMER---QVKATLKQN- 72  fission yeast
585063    88 sTKKpviKkSLNSSPlfGLSIpktptlkkrklhgpfslsDSkqtyNVGseaetnekgnssLKLEFTpgmaedAVGDSApL 167 baker's yeast
19074717     --------------------------------------------------------------------------------     Encephalitozoon cun...
6015008   73 -PER---K-SIKQIP--GMNI------------------DS----ILG------------LPVKTT------ASGDSL-M 104 fission yeast
585063   168 SHAKssdaktPGSSTFQTPTTntpttsrqNvpAGEILDSLNPENIEISSGNPNVgllsteePSyNQVKVEPFyDAKKYKF 247 baker's yeast
19074717   1 -------------------------------------MDFDRQVFKTLSRRSYV-------R--SDIRMAPK----PRVS 30  Encephalitozoon cun...
6015008  105 QESK------PSTETFELNSS--------D--AGRVLEVLNKE-LKIVTSKPSA-------PS-KLVIVANF-DLKAFNY 158 fission yeast
585063   248 RTMRQNLQEASDVLDDQIESFTKIIQNHYKLSPNDFADPTIQSQSEIYAVGRIVPDSPTYDKFLNPESLSLETSRMGGVG 327 baker's yeast
19074717  31 NFY---LRKKDKYEYVRHRLISMKPYFLELLGIEDFKPVNNVSDSSFYTYGIITNP---FGHKLDSESVFIASSIDGSND 104 Encephalitozoon cun...
6015008  159 RIMYQKLYDSSEVLDDRIELFSALTCRKYNISDEDLANPSELTQEPVVVVGRIVVESTNLGGRLNQNSILLESSRRLGAG 238 fission yeast
585063   328 RRVRLDLSQVNELSFFLGQIVAFKGKNANGDYFTVNSILPLP-YPNSPVSTSQELQEFQANLEGSSLKVIVTCGPYFAND 406 baker's yeast
19074717 105 VAVRLNLAHLQRYSVFPGQIVAVKGKNTDGGKMTVEALHCIPvVDINVAKDGEEKKYMQP------T-IVAFSGPYGP-- 175 Encephalitozoon cun...
6015008  239 VRVRLKVDDLPSYSIFPGQIVSVKGSNPSGNMFIAKEILPIPpLP-FPSSSKQEHATFVANTNNQPISIYIASGPWSLRD 317 fission yeast
585063   407 NFSLELLQEFIDSIN-NEVKphVLIMFGPFIDITHPLIASGKLPNfpqfkTQPKTLDELFLKLFTPILKTIS-PhiQTVL 484 baker's yeast
19074717 176 ---G-PEFDALDRVLaEDAD--VLILIGPFIGP----RQYGATQS------PDSMMKEVFIPRIRGWLDRNAgS--KAVL 237 Encephalitozoon cun...
6015008  318 DLSFSPLKSMISYVNkNPVD--LVILCGPFLDINHILIRTGNITG-----TSATSLEELFKERVTPILSQLTcP---CIL 387 fission yeast
585063   485 IPSTKDAISNHAAYPQASLIRKALQLPkRNFKCMANPSSFQINEIYFGCSNVDTFKDL--KEVIKGG-----------TT 551 baker's yeast
19074717 238 VPSTNDMT-CLNVFPQGPIGVNDERIV-----CTGNPCEFFVNEILVAISSLDTPLEIssEECFHDSgmecsddacgkLL 311 Encephalitozoon cun...
6015008  388 IPHINDAASDHPAWPQDAFNRVALGLP-SNFKCFPNPCMFSINDVVFGVSTNDILLHTsrEELFR-------------LP 453 fission yeast
585063   552 SSRYRLDRVSEHILQQRRYYPIFPGSIRTRIKPkdvstkketndmeskeekvyehisgADLDVSYLGLTEFVGG-FSPDI 630 baker's yeast
19074717 312 FGGDRLGRISYHLIFQRTFLPVFP-----------------------------------SMNVVSYSVPESMSMdTAPDI 356 Encephalitozoon cun...
6015008  454 SHGNLFARLVSHVLHQRHFYPLFPGGSLEKCNP-------------------------SNLDIAHLKLGEFLN--TMPDI 506 fission yeast
585063   631 MIIPSELQHFARVVQNVVVINPGRFIRATgNRGSYAQITVQcPdLEDGKLTlvEGEEPVYLHNVWKRARVDLIAS 705 baker's yeast
19074717 357 YIVASKLKHFCRDVGPSIVVNIGLQAKET--EKIACHIRLP----EAGEKK--KPTVEFVGHPDPARNRK----- 418 Encephalitozoon cuniculi
6015008  507 LILPSDLRYFVKNVENVVSLNPGKATKGI-NLGTFAKLTIA-P-LELG--D--NGSSNHYSHRVWLRTKAEILKL 574 fission yeast
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