CDD Conserved Protein Domain Family: TopG2

Sequence Alignment

include consensus sequence

Format: Row Display: Color Bits: Type Selection:

WP_082419467   37 GWEPARGVYVYSCPNCGGPVGDDRLLLGLPCPRCLPERV-------AVES----PLDAAEVLAKTGRLrqgSPLEFYARV 105 
ADM28742       18 LLKIPRGIYLGLCINCGGPIEDNRIIYRNACSKCMNSKDl-----vEVRD----LEELAKHVTSLNPN---GRLNYILTL 85  
AFH42708        3 LGLMIKAVFQSLCPSCAGPISSYRLSLGVPCNSCLPSSKldnmediSKYPlekkIRLISKSLSDNPQ----SAYHLMRDT 78  
NP_213790      16 PIIMALELIERGCPNCGGVISSDRLEKGLPCSKCLPKPT---------------EEKVCDALEELKTL---KYLKPFCDT 77  
WP_012185865    9 GSGEPLVLYHGMCPNCGGPVTSDRLRDGLPCHVCLPEGSr-----lRAAS----LRVVLSELNREGRL---VRLRDIFNY 76  
WP_013337362    1 MEKQPLVIYRRACPNCGGDITSDRLASGLPCHRCLPDVPk------KVAS----TIEVLNMLEKLGTI---NRLRSLANL 67  
WP_013537659    1 ---MKVAEFHRMCPNCGRIISDKRLKAGLPCERCLPEFL-------KWKE----REEICEAI---EEL---QNFQQICRL 60  
WP_013637986    1 ---MKLAEFHRMCPNCGGIISDERLKAGLPCEKCLPKEL-------FYTN----RKEICNAL--GNKL---QDFKKICLL 61  
WP_013908056    1 ----MLFLVAHACPNCGGTISDERLNRGLPCSKCLPVPT---------------EQDVCQALEEKGQL---KRLSLFCNA 58  
WP_015232464    1 --MSLNPIFRHLCPNCGKEITSDRLEKGLPCKVCLETEL-------EDND----PILIGEMLKKSGKL---YGYSWLYYL 64

WP_082419467  106 EREAREVEALFEKATGSRLWSAQRTWVRRVLKGKSFAAIAPTGVGKTTFGVLMAVYLA-LR--GEKSYIVVPTTPLVRMV 182 
ADM28742       86 NKFVKEFEEFFQKSIGSKPWSLEISWALRVAQHQSFAMIAPTGVGKTTFGLVMTLFLS-YKy-GKKVYIIVPTTVLVEEY 163 
AFH42708       79 FEELESFEKLFRESTGKNIWSLQKTWAHRLLLGESFAITAPTGVGKTTLLLHYAAYQL-KK--GEKVYILVPTESLLNQT 155 
NP_213790      78 DKSLERFINFFEKAVGAKPWSLQRVWAKRVFMNQSFAIVAPTGVGKTTFGLVMSLFLK------GRVLAIFPTRLLAQQA 151 
WP_012185865   77 LMKYDEFSELFRKATGTSMWGAQRFWAKRLIKGKSFAIIAPTGSGKTTFGLVASIYVA-SK--GGRVLMVFPTSTLAYQV 153 
WP_013337362   68 VNEYNEFADMFRKIIGTNMWGAQRLWARRIIKGKSFAIVAPTGSGKTTFGMIASLYVAlKR--RGRVLIVVPTSTLAYDV 145 
WP_013537659   61 DRFVKEFTEFFKEKTGFTPWSLQIMWAKRVALKKSFTMIAPTGVGKTTWGLVTSAFVK------GKVYVLVPTKLLVLQT 134 
WP_013637986   62 DEFTENYVKFFKEKTGFTPWTLQVMWARRVALSKSFTMIAPTGVGKTTWGLVTSAYLS------GKVYILVPTKLLVLQT 135 
WP_013908056   59 LSELDKFRHYFQKAVGFWPSSLQETWIKRLLLRESFAILAPTGTGKTTFGLLTSLYFA------GKVLILVPTRLLAQQI 132 
WP_015232464   65 ENSFREFKEYFEKTTGYILSSAQKSWARRLLYPESFSIVAPTGVGKSTLLMVYTAFRA-INgsDKKIMYLTPTENLVAQT 143

WP_082419467  183 EERARRLADAAGVPARIIALHSRLSQRQRRQLLQLVEEGDFDILITTSQYMIRNAETLASlrerwgR-GFRFVFVDDVDA 261 
ADM28742      164 EKRLWQFSEKLGITLKIIAASSKIHGKRKIELEESIASGSFDILITTSAFLQRNFNDVFKkmlsnnI-KMDLIFVDDVDA 242 
AFH42708      156 EEKLKEICYKMGIDAEIVVYQSRASKKKREEVLKKIEEGKFGVLITTTSFLSRRYDILKK------L-KFDLIVVDDADS 228 
NP_213790     152 GDRLSELAQKVGVNKKILIYQS------KKNIREQFLNGDWDILLGTNMFLHKNFENLIN------F-KFKLIFIDDIDS 218 
WP_012185865  154 YKRALTYRDSAAVNIKVITYNGLLSEKDKSEVLNAIKAGDFNILIVTNAFLPKGMEILSK------Y-RFDLVFVDDVDS 226 
WP_013337362  146 HRRLSDYVNKMGVNVRIVMASSILSKQELTEAMKTIEDGNFDILIVTNAFLPRHMDLLSR------Y-RFSLIFVDDVDS 218 
WP_013537659  135 VERLKKLTDK-----KVVAYTG------KKREKETIASGEFEILVTTTNFLYRNFEIIPK--------PFDFVFVDDVDS 195 
WP_013637986  136 VEKLSKLTNK-----KIVAYTG------KKSEKGTIQSGNFEILVTTTNFLYRNFEIIPK--------PFDFVFVDDVDS 196 
WP_013908056  133 GERLEEFSQKTGIKRQILAYLG------KKKDKETFASQNFDILVCTTAFFYKHLDELLD------L-DFEFVFIDDVDS 199 
WP_015232464  144 YERLKAFLND-----GIAFYYSSMPKKLKEEMTTKINNGEFKILIITPGYLMKNFNKLKE------YsPFGLIVVDDVDS 212

WP_082419467  262 VLK-SGKSVDAVLRVVGFGKEEVELGWRLLQLQRRLVWEAqraQqefnrrlqrlreamrrrgrriraedirelrkrvFEE 340 
ADM28742      243 IIK-GSKAIDMVLQLLGFSEEDISNGYKMIDLRRRLLQCEn-aR---------------------------------ESS 287 
AFH42708      229 LLK-NSVNIEKVLVLIGFDEDDVKIAERLIKCRNELFFYLg-tN---------------------------------NKE 273 
NP_213790     219 FLK-RGKNVDYLFKLLGFSGEEIKLALKENK------------------------------------------------- 248 
WP_012185865  227 VMKaSSRNIERLLQLLGVPREAIDKALEIAKISD---------------------------------------------- 260 
WP_013337362  219 VLKaSSKNIDRLLLLLGINEEALRKALTVVDLMKKLRKAIrfrA---------------------------------SEE 265 
WP_013537659  196 LLK-SAKNVDKVIMLLGFTEEDVELAMKVIDLKAKAAKS--------------------------------------SGR 236 
WP_013637986  197 LLK-SAKNVDKVIRLLGFTEEDISIAEKVLELKSLVAKF--------------------------------------GEK 237 
WP_013908056  200 FLK-RSAHIDKLFKLLGFSEREIALALKPQK------------------------------------------------- 229 
WP_015232464  213 LLR-NSKNIDRVLVLLGYSQESVEIAYELVNKKMNYGIALs-nK---------------------------------KED 257

WP_082419467  341 R----LEPLYRELREVEQRLEE--ARSRAAVLVVSSATGRP-RGSRVRLFQALLGFQAGSAGEAIRNIVDSYTFPg---P 410 
ADM28742      288 RcyidGKPIDVIYEELQKKVLE--KRERCGILIVASATGRA-RGKRIKLFRELLGFSIGTAIEVNRNVVDAYIPId--nP 362 
AFH42708      274 K----TENLKKGCEELEVSLEEakAKKKIGQLAVASATGRQ-AGSKPKLFKELLGFEIGGIHDYMRNIIDSFYLYk--eD 346 
NP_213790     249 -----TQRDYDRLARIr-------KRKRDTVLIVSSATLKP-RGKRAYLFRNLLGFDVQKAITTLRNIVDVAEPVk--dL 313 
WP_012185865  261 -----FKEREGKVSELRRi----lEGRRIGSLIVSGMLTRTrRTARAALFREILGFDVGGRAEGLRNVVDLYIKP----K 327 
WP_013337362  266 E----INKIREDIKRLNAELTNyiKSNNIGILIASGALTRMrRTARLFLFREFLGFETGGRAEGLRNVVDVYVRP----R 337 
WP_013537659  237 E----LQKLLERIKRLEKHLERr-REEIDRVLVVSSATSQP-RSKRVKLFRELLGFEVGKSATALRNVEDVLIFT----E 306 
WP_013637986  238 V----DRKLIEKLKKLENFLEKr-KSEIKNVLVVSSATSQP-KSKRVKLFRELLGFEVGKSATALRNVEDVLIYT----D 307 
WP_013908056  230 -----TEKDFEKLEAIRk------RHAGKKILLMSSATLRP-RTTRVLLFRYLLGFEVQRAVSSLRNVVDAYKDMsssdL 297 
WP_015232464  258 K----IKQLEQEISDLQMKLLLsnNEEMKGQLIIASATGRP-KGIKHLIFRELLGFEIGGGTDYLRNVIDTYKIS----- 327

WP_082419467  411 EGLEAKVVELVAKLGDGGLVYVPVDRGAEYAERLAELLREHGIAAEAFTSRNQ-EALDRFRMGETQVLVGVAVYYGVAVR 489 
ADM28742      363 AEIIDRLVSIIKILGSGGLIYVPLDLGQEYAVKLATELNSRGIRAGVVISGKS-EDLKKFIENELDVVVGVATYYGLLVR 441 
AFH42708      347 KELIEKIKEIVNNLGSGGLIFVSKDLGVNRAKELVKELEDEGIKTSLATA-GK-SVIKKLARGEVQVLVGVSSYYGVIVR 424 
NP_213790     314 EEALEKSVELIKKLGKGGLVYLSVFYGKDKVQEVKEFYRKHGINAVSYLDYKPeELYQILEKGEFDVAVGISHITNPLVR 393 
WP_012185865  328 GDLKVIILDLIRRLGDGGIIYVPTDLGREFAEELSKFLNDNGINAGLYLKPKR-KLIEGFEDGSIPVLIGLATSRSALVR 406 
WP_013337362  338 DSLISTAVDIVKRLGSGGIIYVPPDL-RDIVDELLEALNKNGVKAASYLKPSK-SLLNDFVEGKIDVLIGLATSRSSLVR 415 
WP_013537659  307 KDELQLAVETVKKFGKGVFLFVSADRGREYVDRVVETLNSNGIPAVSYEEFTP-ENQQRFVNGEIWAAVGISSYRNPLAR 385 
WP_013637986  308 KDYLEETVKIIKKYGKGVFVFISEDLGKDYVEEVVNFLNKKGISTVSYENFSS-ENQGNFIDGKIQAVVGIASYRNPLAR 386 
WP_013908056  298 AGLLQKAAELVKILGPGGLLFLSQSYGKDQVENVVEFLRAKGFKVLSYLELSPkEIMAQMETGDFDVAVGLAHLANPLVR 377 
WP_015232464  328 NSVFKDTVELVKKLGNGGIIFISQSYGKNAVKPLLEMLKENGINAIQAISNSR-RAIEKLQRNEVSVIVGLASRYGTIVR 406

WP_082419467  490 GLDLPDRIRYAVFAGVPRLKFSARFEDPHPVSMLRALAVLAEHGPRDVAERAQMLLGRLRGIVRRLSQAALARVAEELRG 569 
ADM28742      442 GIDIPERIRYAIFVGVPRHKISLTRIEYYPQTLLRLLSVLVDVVEDQMKDRVLRNIAYLRRILRRISPNRIFDIVERLKK 521 
AFH42708      425 GIDLPEVIKYAIFVGVPKNKMPLNSALFSPRRLLQALIYISDKDE-----NIKARFEDLQSKINKLNPGEQFALRIALQK 499 
NP_213790     394 GIDLPHIIRYAVFLDPPKHVFPTELTL-SPPLLHGLLLTLLNLFEGDDRLKAIQYVMYLKRYL---------TLREEQLD 463 
WP_012185865  407 GIDLPHRIRYVVFAGVPKIRFRLSLKEFNPGRYIMLLSSLRVIAPSEYKTRIDKTVSSLRNIMn-LSQDRINKIIEAIER 485 
WP_013337362  416 GIDLPQRIAYVVFVGVPRMRFRLRLEEFTPIRYLMFLFTIRNVVPQYLRNDIDRVVARLRNLTa-LNQEQINNLLKAIEE 494 
WP_013537659  386 GIDLPQAVRYALFLGVPKMEFGVKLSL-SPVKLFGLLLVLRELFSEEELPKVNGYISYLKRYL---------TLKEELLD 455 
WP_013637986  387 GIDLPQAVRYAVFLGVPKLEFNLKLSL-APVKLFGILLVLRELIE--DKTKVMSYLSYLKKYL---------SLKKELLD 454 
WP_013908056  378 GIDLPYILRYALFLGVPKHVIPTKVDL-LPRSLFNVLANIIGILDEEERLKAMADLQYLRRYL---------TLTQENLP 447 
WP_015232464  407 GIDLPEIIRYAIFIGTPARKLELKTALISPQRLLRIVMFLEEKDQ-----SFSSLRKSLESFLSKYGE-QSPLVAAVLRG 480

WP_082419467  570 E------RPlESDAAKAFAEALEWLRETMKRED-VWQAL-EEAdDIAV-VREGERAYILVPDVATYIQASGRTSRLFAGG 640 
ADM28742      522 Ge-----KV-EDELAGIITNAYKLVNELLSDSK-IIDRL-KKHeRVSI-IEEEGQLYILIPDAPTYIQASGRTSRLFMGG 592 
AFH42708      500 GttkqlsGW-LGEVADVILKTISEVTIKLDSIIpREKGAvLNLgTSLIeRGEDGSLYYINPDPLTYIQASGRTSRFLNDK 578 
NP_213790     464 N---------YPRIKERVEEIKNFLENYLKDEN-FLKKI-KESeDISL-VPKEGKLYIVVGDANSYIQASGRTSRFIAGG 531 
WP_012185865  486 Ges--lqGF-DKYASEVISNAIKLAQDLLNRDD-VREAM--SKsIVNI-QRMGDDIYVILPDSPAYIQGSGRTSRMYLGG 558 
WP_013337362  495 Nke--lsGF-DKYAADVIKEAVDLVNKLLSDPN-IRKAI-EQSnEVGL-EYRGGELYVIIPDVTTYIQGSGRTSRLYVGG 568 
WP_013537659  456 R---------YPKIKSRLQEIKEFLEAHLSNPE-FLKKI-RESeTVSL-KEKNGELVLVVGDAAGYVQASGRTSRMFAGG 523 
WP_013637986  455 K---------YPKVKEKLEEIKGFLESYLSNKE-FLEKV-RASeDISL-KEKNGELFVVVGDATGYVQASGRTSRMFAGG 522 
WP_013908056  448 K---------YPRILERLKEIKAFVDNKFKDEA-FLERL-SKSeDVFL-VKEGEELFLVVGDTATYIQASGRVSRLTAHG 515 
WP_015232464  481 Ele--akGI-LKTMKEVINNSIPKVYNAILNYVpNDGNI-IKIgSFVI-RNEKNALYLYSSDGPTYLQASGRTSRLYYGH 555

WP_082419467  641 ITRGLSVVVVDDPRLLNGLMRRTR-WLV--EAEWKRF-----------------EELDLPSLLREINRDRERVRAVLEGR 700 
ADM28742      593 ITRGLSIIFVDDTRLLRGLEERIR-VYId-DFRFQSF-----------------NEINLEEILKQIDEDRRIVNLIKRGL 653 
AFH42708      579 MTLGFCLIFEKSKEYLEVFKKKIG-NYVy-SFDPKEL-----------------SSINLKEISERLILSRMGKDGs---- 635 
NP_213790     532 MTKGLSVVYYSDPKAFYSLKKRLAlYYMtqEIEFKRL-----------------SEVDLNKLIKEIDEDRKRAREILQGK 594 
WP_012185865  559 ITHGLSVLIVDNEAVFNSLSRDLR-YRLv-DFQFINY-----------------EEFNVDALLKTINEERELIRQIMTGN 619 
WP_013337362  569 VSQGLSVLIVDNEKVFNGLIRNLR-YRLe-DVKIQDI-----------------NEVNIDDLMKRIRSERDLIRNIMLGK 629 
WP_013537659  524 LTKGVSLMVVDDVKALNSLRKRVM-LFLe-DVEFKVLetdkgkefagklglptiTEEELKAVFKQVDRDRKRVREILEGK 601 
WP_013637986  523 LTKGVSLMLVDDLKALNSLKKRLS-IFLe-DLNFKVLdydkgkelaekfgfeliDEEKLNKIFKTVDEDRKRVKEILEGK 600 
WP_013908056  516 LLKGLSVVLVEDLRAFRSLERRLR-FQLgeEFSFVPL-----------------ENLDLKELSCELTEVRQLKRNAKGa- 576 
WP_015232464  556 MTKGLSIIIDEMPELVESMSEKLR-WIs--QANFVKF-----------------EDINLDEVIKELEESRKINGG----- 610

WP_082419467  701 VKp----eFMELVKTALLVVESPNKARTIAGFFGRPSARQIGPLRVYEVSTGD------YVLLVAASGGHIYDLVKPATp 770 
ADM28742      654 LEevihipKFSFSRSILFIVESPNKARTIASFFGRPTIREIDGLRVYEVDIGN------AHLLIASSGGHVFDIVEEELs 727 
AFH42708      636 -------kSFKPAKSIMFVVESPHKAKTIAGFFGRPAKRRFGSVVVYEIPIVDqetletYLAMIVATKGHLFDLVSDN-- 706 
NP_213790     595 GVa----qIKDLFKTTLVIVESPNKARTIAGFFGKPQMRLVEDSVAYEVPLGD------RLLVITASLGHVLDLVT---- 660 
WP_012185865  620 VPqs--isQVDPLKSVLVIVESPTKARTIANFFGKPSTRVLGSLIVYEVTSGN------LLLNIIATKGHVVELATEQYa 691 
WP_013337362  630 IPnq--flEKDPLRTAFVIVESPTKARTIASFFGVPTRRNVGPLIIYEATLGN------LYLLITATKGHMWDLIPAGPa 701 
WP_013537659  602 VTp----eTKSLVTTALVVVESPNKARTIANFFGKPVRRRVKDVDAYEINIGN------KLLLLAASKGHVFDLTV---- 667 
WP_013637986  601 IKa----eTKNLVNTALIVVESPNKARTIANFFGKPVRRKVLDIDVYEINIGD------RLLLLTASKGHVFDLTV---- 666 
WP_013908056  577 --------SRDFIKTALVVVESPHKAKTIASFFGKPAVRKVGEAFVYEIPAED------KVLMITASLGHVFNLSR---- 638 
WP_015232464  611 --------KKVNIVSELIIVESPTKAKTISSFWGKPARRREGNLNIYETTTVDpltntvYLLTITASKGHVYELIVDDN- 681

WP_082419467  771 revvepgwlldllkdsvegydwesARNVHGVL--VAGDggrRFLPVYTPLARCLACGHQWAVSPEdynpvtgrgelRCPV 848 
ADM28742      728 ------------------------ENNIYGVQrtVENGk-qLFLPIYGYLKRCSVCGAQFVKG-T-----------VCPI 770 
AFH42708      707 ------------------------NIGTYGVI--KVNE---EFIPVYAPISKCLSCGRTFVSLHN-----------KCPY 746 
NP_213790     661 ------------------------DKGFFGVL--DDTY---PYLPVYDTIKICRETHEQHTEYEY-----------LKKR 700 
WP_012185865  692 qsvssdvd-------yvtkfissvTRNYYSVL--KIDG---NFIPIYSTIKRCPTCGRSFTDDVS-----------KCPF 748 
WP_013337362  702 dvkela-----------palragkIIDYYGIL--KTGN---NFVPIYGTIKRCPVGGETYTEDVD-----------VCKI 754 
WP_013537659  668 ------------------------RDGVWGVK--EEDG---HYIPVYDTIKYCTKCNEQTTEN-------------FCTK 705 
WP_013637986  667 ------------------------RDGLWGVK--EEES---SYIPVYDTIKYCTKCFEQTTEP-------------FCSK 704 
WP_013908056  639 ------------------------RRGFFGVF--KENS---RFVPMFDSIKICEPTKEQLVDPEE-----------VKTR 678 
WP_015232464  682 ------------------------TDSCYGIK--INDS---VISPLYTSIKRCLKCGYQFTQETN-----------ECPR 721

WP_082419467  849 CGSPL-VKNSWDIVEALRDLASEVDVVMIGTDPDTEGEKIGWDLASLIRPTARGIVRVEFHEITRRAILEAIHGARPFLE 927 
ADM28742      771 CGSTR-IRSSEKIINALQKIALEVDEVIIATDPDSEGEKIGYDMAIALAPYAKIIRRAEFHEVTRKAILSSLYNPRGLKL 849 
AFH42708      747 CGESFkIKSSMETVHVLRKIAMESEEIYIATDPDVEGEKIAWDVEMAIKPYNSKIIRAEFHEVTREAILEAIRNPRKIDE 826 
NP_213790     701 C-KGK-IEDKLEIIKGVREVSYEVDEVFIATDPDAEGEKIGYDLYLLSKPFNFNIKRAEFHEVTPKAFREAIQNPREVDL 778 
WP_012185865  749 DGTP--LVDSSGVIEMLRDLATEVDLVLVGTDPDSEGEKIAWDVFNMLRPFVQDIRRIEFHEVTKRAILNALANPRGVNG 826 
WP_013337362  755 HGVK--LVDAMDIVNAIRDIATEVDQVMIGTDPDAEGEKIAWDVYMMLRPYVSNIVRIEFHEVTKKAIIDAITNPRAISL 832 
WP_013537659  706 CEGRP-DVDKITVVEALRELGLEIDEVYIASDPDTEGEKIGWDVGCNLKPYQMNMKRMEFHEITKWAFLKALEEPREIDE 784 
WP_013637986  705 CSGKP-DVDKITVVRALREVGLEIDEVYIASDPDTEGEKIGWDIGTVIKPFQKKVRRMEFHEVTKWAFMEALKTPKEIDE 783 
WP_013908056  679 CPEGR-IYDKRELLESLRKLAFEIEEVYIGSDPDAEGEKIAYDLLIEMRPFNSNIRRLEFHEVTSRAFREAIKNPEEFNL 757 
WP_015232464  722 CGSSI-VVTSESILQSIKRLATEVDQILIMTDPDREGEKIAWDLYLALRPYNKNIYRSAFHEVTLNAVLEALRNPGKLNK 800

WP_082419467  928 RLVEAQIVRRVEDRWIGFTLSPVLWTRFwpwfcrwsltarhrsarrnlktatamlnameqmarlreecdrPNYNLSAGRV 1007
ADM28742      850 SLIEAQIVRRIEDRWLGFALSDYVTKRFkelk-----------------------------------lesREGRLSAGRV 894 
AFH42708      827 SQVSSQILRRVTDRWIGFPLSSRLWSEF------------------------------------------QKPWLGAGRV 864 
NP_213790     779 NLVKAQLVRRILDRWVGFTLSHILWDAF------------------------------------------GKKWLSAGRV 816 
WP_012185865  827 NMVKAQLVRRIEDRWIGFGLSSYLQRAF------------------------------------------NDRNMSAGRV 864 
WP_013337362  833 SMVGAQLVRRIEDRWIGFGLSQIVQEKF------------------------------------------GRRTLSAGRV 870 
WP_013537659  785 NLVKAQIVRRVADRWVGFSLSQHLWKVF------------------------------------------NRRWLSAGRV 822 
WP_013637986  784 NLVKAQIVRRIADRWVGFALSQHLWKVF------------------------------------------KKHWLSAGRV 821 
WP_013908056  758 NRVKAQLTRRVVDRWVGFVLSRKLWEAF------------------------------------------GRKRLSAGRV 795 
WP_015232464  801 GLVNAQISRRIDDRWVGFSTSKYLQNKY------------------------------------------SKLWLGAGRV 838

WP_082419467 1008 QTPVLGWIVEHTLGSRFlRVPLYRL--RLRGekGELELELRGDE---ASDRIRAALEeakraleealqrhnvlesleele 1082
ADM28742      895 QTPVLGRVIEIYINRLRtQRKYKIF--SIGN--ISLEIPVEDLK-----KIFGDELKri--------------------- 944 
AFH42708      865 QTPTLGWIISRHEEWKNaRGYWVRI--PLINl-FAVKLFKKDKK---EAEDLKNAII----------------------- 915 
NP_213790     817 QTPVLGWVIKRYEES-KeKKGEILL--HVND--FPLKIEIEDLM---FAKEIFKDLE----------------------- 865 
WP_012185865  865 QTPVLKWIIERYIEYRRnRVIRLIVrkRISDg-KVLEVSFDKVTngdETARVRHDLRdva-------------------- 923 
WP_013337362  871 QTPVLGWIIERYDESRRdKVYSVTM--TLSNg-VKVRLNIPPDK-----EELIKALKamhrn------------------ 924 
WP_013537659  823 QTPVLGWVIERFEES-KeKIGLLTV--ECEG--VSFTFKLEEPQ---KLKEV---------------------------- 866 
WP_013637986  822 QTPVLGWVIKRYEES-KeKKGIIVV--ETKA--GSFRFEFDNLE---EFQKI---------------------------- 865 
WP_013908056  796 QTPVLGWVIERADEA-KqKKALISF--KLFN--ETFNLTIEDLK---LARRVFEALD----------------------- 844 
WP_015232464  839 QTPVLGWIIDRYNEYKKeLGYKIKV--KLPSg-NYIYYYTKDKE---QAENAV--------------------------- 885

WP_082419467 1083 avrrrkarvirevnealergGAVRATVGDVEEWEDELKPLPPFTTDALLAEAASRLGLAAPEAMRLAQDLFELGLITYHR 1162
ADM28742      945 ------------------skERVEIVLKLLSHEIVNLNPMPPFTTDELIVEAQRQLGIDAVETMRIAQDLFELGFITYHR 1006
AFH42708      916 --------------------KSGSLKIDSYEIYEQQLLPPPPYTTDELLHDANMVYGYGAQFTMKLSQDLFEAGLITYHR 975 
NP_213790     866 -----------------------LADISLSNPQEEEKRPLPPYTTDTVLEDANEKLHLSAHKTMKILQELFEAGYITYHR 922 
WP_012185865  924 -----------------kdkKGLRIIITKLSESEEEVNPPPPFTTDSMLTEATARLRAGTEEVMRLAQELFEMGLITYHR 986 
WP_013337362  925 ----------------kstdVEVKVRVTKVGEEEEELNPAPPYTTDALLRDSANILGLSVEQTMAIAQELFESGLITYHR 988 
WP_013537659  867 --------------------KADKVKVKVREVSVTEKNPKPPFNTGELLKEAADRLKLSAERVMEVAQELFESGFITYHR 926 
WP_013637986  866 --------------------AIDKVEIKVKEKSIFEKNSLPPFNTGELLKEASNNLGISAEETMNIAQALFESGFITYHR 925 
WP_013908056  845 -----------------------ELSWEILEQKEEEKNPFPPYTTDTVLQDASQRLKFSTRETMNLLQDLFENGLITYHR 901 
WP_015232464  886 --------------------KNSKIKLKTLRIYNEEMNPLPPYTTDALIYDASQKYGFTAQITMKLAQDLFYSGLITYHR 945

WP_082419467 1163 TDSTRVSDAG-IAVAWEYLRYRYGEDRleevFQPRRW--GE--GGAHEAIRPTRPIDAETLRRLVEEGALQLARPLTQRH 1237
ADM28742     1007 TDSTRISSTG-ISIAHEYLLNKFGDLGke-lFVPRTW--GE--GGAHEAIRPTRAMDVDMIQEIIAEQLIELPIRLTNRH 1080
AFH42708      976 TDSTHVSNKG-IQIASEYLSKGIGKPEi---FYPRSW--GS--EGTHEAIRPTKALSASDLKKSIVDGTLKTYINVTEAH 1047
NP_213790     923 TDSTRVSDAGkYLVAKPYITKMFGEEY----FYPRSW--GE--GGAHECIRPTRPLEPKDLEFMITAGIAEF--EDPENA 992 
WP_012185865  987 TDSTRVSAVG-ISVAKEYLTNRFGEGV----FTAREWgmGE--EGAHECIRPTRPIDSEELRSLIDSGVLKL--KLTNRH 1057
WP_013337362  989 TDSTRVSTVG-IGIAKEYISERVGADY----FVGRAW--GGkeIGAHECIRPTRPIDSDDLRNLINTGLLQLAIRVTANH 1061
WP_013537659  927 TDSTRVSTAG-MGVAKEFITERFGPQF----VKLRPW--GE--GGAHECIRPTRPLDAEGLRTLVTVSGSTV--KMERDH 995 
WP_013637986  926 TDSTRVSTAG-MGVAKEYISQKFGAEF----IKLRSW--GD--GGAHECIRPTRPLDAESLKALVLVSGSSS--KMTKNH 994 
WP_013908056  902 TDSTRISEAGrYQVAKPYITEKFGEDY----FYPRAW--GE--GGAHEGIRPTRPRDVHEIRLMLANGLLTL--AEPERA 971 
WP_015232464  946 TDSIRISQLG-IQVAKEYLQKNNLLQY----FKPRTW--SE--EGAHEAIRTTRPLNAQELERGILERTIKVPIELTQYH 1016

WP_082419467 1238 YRLYDLIFRRFIASQMRPARVRKQRAKVVLeiRLP-GeqpkrIER-VVERTVEVLERGWLEVYPVAR----PQPRVA-P- 1309
ADM28742     1081 LRIYDIIFRRFIASQMKSAKVERNRFEAIL--KID-Gie--vAKQ-HIEIISNIVEPGYTLIYMPFK----TV-FLP-H- 1147
AFH42708     1048 IKLYDLIFRRFIASQSRPSVVEKLKLNLSI--SYNrE-----KEVfEKELILREKETGFYGLLYNINeqtqIADYIK-E- 1118
NP_213790     993 LKVYELIFKRFMASQMRPAKVITEEIILKL----P-Y-----FEW-KERVVTEVKEHGFDLMYPTFK----VF-PKK-E- 1054
WP_012185865 1058 IALYDLIFRRFMASQMQSGLVKKVKVEVKL--MRN-Gdm--lSSR-VDEFVTSVIRNGFLAIYPTIR----VT-QFP-E- 1124
WP_013337362 1062 LKVYDLIFRRFMASQMRSARVLKEKLRISI--YLN-Gan--vHEE-EVERVSKILEPGFTKVWGYIEg--rEYQELM-P- 1131
WP_013537659  996 YAVYDLIFRRFIASQMVPAEVERVKAEVKL--LPD-E-----LQK-EEEFTTKITKDGWNLILPQIE----VT-ELPfEp 1061
WP_013637986  995 FRIYDLIFKRFMASQMIPTKVEKCKLLVKL--LPV-E-----KEE-EEERIAKIVKNGWNLIQP-LN----LE-PLSvEl 1059
WP_013908056  972 LKLYDLIFKRFMASQMRPALVEKTIIRFSL----P-F-----YNW-EEEIITQILRDGFEKLYPTFK----VV-SLS-P- 1033
WP_015232464 1017 YKLYQMIFERFLASQMTSSIIEKAVVRISL----G-E-----LTI-EKDFNVSIIKDGFTLISK-PI----IENWIKkEp 1080

WP_082419467 1310 --G--EY--RLE---ELRVRVWSPVQLLTQAEVVRMMKERGIGRPSTYAKIIDTLLRRGYVVTAGR-AGSMIATSRGIGV 1379
ADM28742     1148 --G--SIalKPL---HIKTAILSDVKLPTQGDLVKWMKDVGIGRPSTYAKIVEILLRRGYTFRHRK-GSVLIPSITGIII 1219
AFH42708     1119 --G--RIpvDVS---KVEIYRGSLIPLYTQGEIVKLMKEKKIGRPSTYAKILDSLRRHGYVVISKK-RNFVIPTNTGIKV 1190
NP_213790    1055 -----KL--EIT---HKEFREVPKVYPYTQGTLIQEMKRRGLGRPSTYAQIVQTLLERHYVVEE---KGFLIPTDLGREV 1121
WP_012185865 1125 --SsmEL--PVTeedEVIVKTVHTTYPYREGDIVAEMKRRRIGRPSTYAKIIETLKRRGYVKALGS-TKVLIPTKRGVAA 1199
WP_013337362 1132 --G--EY--GITs--IDYIKKVSRTPPLREGDIIAMMKERGIGRPSTYAKIVDVILKRRYALVVGRrTRYVVPTNLGRQV 1203
WP_013537659 1062 teGe-SYylPVK---AVHKRLIPKVLPYTQGELVEEMRKRRIGRPSTYAKIVQTLLDRKYVVER---RHRLYPTKLGIEV 1134
WP_013637986 1060 kkEk-TYyfEII---SYVKKKVPKVFPYTQGELIEEMRKKEIGRPSTYAKIVQTLLDRKYIIEK---GKFLYPTKLGIEV 1132
WP_013908056 1034 -----QA--GLQ---EKGYKLVPKVELFTEGTLVQEMKRRGLGRPSTYAEIVTTLIQRKYVKVLP--GGRLTPTRLGREV 1101
WP_015232464 1081 -nAeyEI--NVD---NVIYYKGSLIEPYKNGDLVMLMKKKNIGRPSTYAKVIESNIRHGYVIESKK-QKYMIPTKNGIEI 1153

WP_082419467 1380 YDFLM----------------------K-------------------------------R-F------------------ 1387
ADM28742     1220 YNILAgtmlpsievdeeefinilqkhpSi-----------------------------rK-Ynpealrqtlaeilrnlsi 1269
AFH42708     1191 YQYLS----------------------S-------------------------------N-Y------------------ 1198
NP_213790    1122 YEYLT----------------------K-------------------------------H-F------------------ 1129
WP_012185865 1200 YICLS----------------------NdkdvaklylstrrnkvqentefesllkqcnvN-F------------------ 1238
WP_013337362 1204 YKFLT----------------------Een----------------------------kE-F------------------ 1214
WP_013537659 1135 YNYLA----------------------E-------------------------------N-F------------------ 1142
WP_013637986 1133 YNYLS----------------------E-------------------------------K-F------------------ 1140
WP_013908056 1102 YEFLR----------------------K-------------------------------N-Y------------------ 1109
WP_015232464 1154 YQDLM----------------------G-------------------------------SiF------------------ 1162

WP_082419467 1388 --GGLVSEEVTRRLQETMDRIEEGLVDYQRVLEEVLEKLREA-----LYSPESGLPE 1437
ADM28742     1270 giRNMVSVERTRMLYNKMQEIEEGRLSYINVLSELFREMCSN-----VINMISSEAI 1321
AFH42708     1199 --SSLVSEETTRKLEEDMDAIEEGKESYLALLAKLYDALTRL-----GLISEVELAA 1248
NP_213790    1130 --PEWTSEELTRKLEEAMDKIERGELDYMEVLKEVHRIKVLLkeekafkk------- 1177
WP_012185865 1239 --KCLISEDRTRMVEEHMDNIENGDEDYLTVLHELFNEAVKYg----IMPQN----- 1284
WP_013337362 1215 --SDLVSEERTRIVERHMDDVEVGERDYMDVLNELFNEAVSKg----ILKENVIT-- 1263
WP_013537659 1143 --PHYTSEEFTRELEELMDKVERGEADYQKIIEELKPVLQFA-----NVDPKQTVGE 1192
WP_013637986 1141 --PDYTSEEFTRELENIMDKVERGEEDYQKVIENLKPILEIRys------------- 1182
WP_013908056 1110 --PQYTDEALTRELEEAMDLIEEGKLDYQKVLAEAYRIRRLLsgepeEHAFEERLTT 1164
WP_015232464 1163 --KELLTEESSRVLEEQLDMIENQKISPIDFINSVYNEIFVKrlnnycr-------- 1209

Conserved Protein Domain FamilyTopG2

Conserved Protein Domain Family
TopG2