15603226 73 GYQSDKEATSTFGALELAKRGFVVLAIDHFgHGYSTKLPASNKNMSGanngyqylKTLPFVDNTRLGLFGHSTGALnair 152 Pasteurella multocida 15806084 1 --------MNTTDHATPLTEGHPYRVERAVlAGVPCLLELPPKDS----------DVRGVCLVYHGAWAAKEGKLG---- 58 Deinococcus radiodu... 15807240 55 VMRRLIAWVLALLLGLAAYIFLTQPQEAGVkLPSLPPLTGPPQTGQPspspessvPHWDDALLRQSVDAQPITIAAlrar 134 Deinococcus radiodu... 15829520 53 RLMWIWRGIDPREILDVQARIVMSDAERTD-DDLYDTVIGYRGGNWI--------YEWATQAMVWQQKACAEEDPQl--- 120 Escherichia coli O1... 20141165 53 RLMWIWRGVDPREILDVQARIVMSDAERTD-DDLYDTVIGYRGGNWI--------YEWAKQAMDWQQKACQEQDAMr--- 120 Salmonella typhimurium 15642274 54 RLQWIWQGVDPVEQEEILARIASSKHSRTH-DEWLDTVMGYRSGNWT--------YEWTRVGMLHQKQAAERQGEEa--- 121 Vibrio cholerae 15790431 42 DAFSAGLQFGELDAEDALEEFRYGLYGQYGeSAGVGDVTTDDGEVSVelvfadgsQHLDLRVADGEVADFALPSEYep-- 119 Halobacterium sp. N... 16123383 53 RLMWTWRGIDPLEIEEVLSRIACSKAEHSN-NELLDTVVGYRNGNWI--------YEWANQGMMWQQKAMEETDPGs--- 120 Yersinia pestis 15799944 53 RLMWIWRGIDPREILDVQARIVMSDAERTD-DDLYDTVIGYRGGNWI--------YEWATQAMVWQQKACAEEDPQl--- 120 Escherichia coli O1... 17865775 53 RLMWIWRGIDPREILDVQARIVMSDAERTD-DDLYDTVIGYRGGNWI--------YEWATQAMVWQQKACAEDDPQl--- 120 Escherichia coli 15806084 1 --------MNTTDHATPLTEGHPYRVERAVlAGVPCLLELPPKDS----------DVRGVCLVYHGAWAAKEGKLG---- 58 Deinococcus radiodu... 15807240 55 VMRRLIAWVLALLLGLAAYIFLTQPQEAGVkLPSLPPLTGPPQTGQPspspessvPHWDDALLRQSVDAQPITIAAlrar 134 Deinococcus radiodu... 15829520 53 RLMWIWRGIDPREILDVQARIVMSDAERTD-DDLYDTVIGYRGGNWI--------YEWATQAMVWQQKACAEEDPQl--- 120 Escherichia coli O1... 20141165 53 RLMWIWRGVDPREILDVQARIVMSDAERTD-DDLYDTVIGYRGGNWI--------YEWAKQAMDWQQKACQEQDAMr--- 120 Salmonella typhimurium 15642274 54 RLQWIWQGVDPVEQEEILARIASSKHSRTH-DEWLDTVMGYRSGNWT--------YEWTRVGMLHQKQAAERQGEEa--- 121 Vibrio cholerae 15790431 42 DAFSAGLQFGELDAEDALEEFRYGLYGQYGeSAGVGDVTTDDGEVSVelvfadgsQHLDLRVADGEVADFALPSEYep-- 119 Halobacterium sp. N... 16123383 53 RLMWTWRGIDPLEIEEVLSRIACSKAEHSN-NELLDTVVGYRNGNWI--------YEWANQGMMWQQKAMEETDPGs--- 120 Yersinia pestis 15799944 53 RLMWIWRGIDPREILDVQARIVMSDAERTD-DDLYDTVIGYRGGNWI--------YEWATQAMVWQQKACAEEDPQl--- 120 Escherichia coli O1... 17865775 53 RLMWIWRGIDPREILDVQARIVMSDAERTD-DDLYDTVIGYRGGNWI--------YEWATQAMVWQQKACAEDDPQl--- 120 Escherichia coli
15603226 153 vaklnpdhkavNGLSSNGGEMTLNNYLLtQGlYEEIGGYRERTfpvkslIHHPNRLKAFGLGENETLQWDHTYGDfntgs 232 Pasteurella multocida 15806084 59 -----------VYSALTTHGIAVVIPDA------ALHGERQGDt-----PPGLNAREYVWDSVRRTVVEAPALLD----- 111 Deinococcus radiodu... 15807240 135 kypgsalsvirTLSPGAGYSRQVVSYQSeGLkIHALLTVPSGTpppggwPAIVFNHGYIPPAEYRTTERYVAYQDafara 214 Deinococcus radiodu... 15829520 121 ----------sGRHWLHAATLYNIAAYP-HL-KGDDLAEQAQA------LSNRAYEEAAQRLPGTMRQMEFTVPGgapit 182 Escherichia coli O1... 20141165 121 ----------sGRYWLHASTLYNIAAYP-HL-KGDELAEQAQA------LANRAYEEAAQRLPGSLREMEFAVPGgspvt 182 Salmonella typhimurium 15642274 122 ----------aDQMFA-AALYYSIAGYP-HL-RNDNLALQAQV------LANNAYQEAAKLTGFVVKRLEFSYQNkkiag 182 Vibrio cholerae 15790431 120 ---------paYADTDAFTERDVTVDAGdVA-LDGTLAVPDGDgp---fAGVVLVHGAGIHDPDGTADESKLLQDfawgl 186 Halobacterium sp. N... 16123383 121 ----------aGQFWLNAANLYSIASYP-HL-KGDELSEQAEV------LSNRAYEEAAKYLPYTLKELTFPISDggsls 182 Yersinia pestis 15799944 121 ----------sGRHWLHAATLYNIAAYP-HL-KGDDLAEQAQA------LSNRAYEEAAQRLPGTMRQMEFTVPGgapit 182 Escherichia coli O1... 17865775 121 ----------sGRHWLHAATLYNIAAYP-HL-KGDDLAEQAQA------LSNRAYEEAAQRLPGTMRQMEFTVPGgapit 182 Escherichia coli 15806084 59 -----------VYSALTTHGIAVVIPDA------ALHGERQGDt-----PPGLNAREYVWDSVRRTVVEAPALLD----- 111 Deinococcus radiodu... 15807240 135 kypgsalsvirTLSPGAGYSRQVVSYQSeGLkIHALLTVPSGTpppggwPAIVFNHGYIPPAEYRTTERYVAYQDafara 214 Deinococcus radiodu... 15829520 121 ----------sGRHWLHAATLYNIAAYP-HL-KGDDLAEQAQA------LSNRAYEEAAQRLPGTMRQMEFTVPGgapit 182 Escherichia coli O1... 20141165 121 ----------sGRYWLHASTLYNIAAYP-HL-KGDELAEQAQA------LANRAYEEAAQRLPGSLREMEFAVPGgspvt 182 Salmonella typhimurium 15642274 122 ----------aDQMFA-AALYYSIAGYP-HL-RNDNLALQAQV------LANNAYQEAAKLTGFVVKRLEFSYQNkkiag 182 Vibrio cholerae 15790431 120 ---------paYADTDAFTERDVTVDAGdVA-LDGTLAVPDGDgp---fAGVVLVHGAGIHDPDGTADESKLLQDfawgl 186 Halobacterium sp. N... 16123383 121 ----------aGQFWLNAANLYSIASYP-HL-KGDELSEQAEV------LSNRAYEEAAKYLPYTLKELTFPISDggsls 182 Yersinia pestis 15799944 121 ----------sGRHWLHAATLYNIAAYP-HL-KGDDLAEQAQA------LSNRAYEEAAQRLPGTMRQMEFTVPGgapit 182 Escherichia coli O1... 17865775 121 ----------sGRHWLHAATLYNIAAYP-HL-KGDDLAEQAQA------LSNRAYEEAAQRLPGTMRQMEFTVPGgapit 182 Escherichia coli
15603226 233 arraamvdgthlgvmiasqsnkeailwfnQALQHGEKgadwiDPDQQTYWYKELTGLFALACALLAtlcfasgllkttyf 312 Pasteurella multocida 15806084 112 ------------------------------ALAGRFGa----GPVLAVGSSMGGYVVQTLLQTEPR-------------- 143 Deinococcus radiodu... 15807240 215 gf---------------------vtlksdYRGHGDSEge-arGGYNDPGYTVDVLNAAASLKKDAR-------------- 258 Deinococcus radiodu... 15829520 183 gflhmpkgdgpf-ptvlmcggldamqtdyYSLYERYF-----APRGIAMLTIDMPSVGFSSKWKLtqdsc--------ll 248 Escherichia coli O1... 20141165 183 aflhmpkgdgpf-ptvlmcggldamqtdyYTLYERYF-----APRGIAMLTLDMPSVGFSSKWKLtqdss--------ll 248 Salmonella typhimurium 15642274 183 ylhlrntdspk--pvvlvsagldslqtdmWRLFRDYL-----AKRDIAMLTIDMPSLGASSHWPLtedss--------cl 247 Vibrio cholerae 15790431 187 ateg----------------iaalryekrLHDHDVAPe----EHTLDTVVVDDAVAALDELASADTvdedalf---vagh 243 Halobacterium sp. N... 16123383 183 gflhmptvgsapfptvlmcggldtlqsdyHRLFRDYL-----EPKGIAMLTIDLPSVGASSRWKLtqdts--------yl 249 Yersinia pestis 15799944 183 gflhmpkgdgpf-ptvlmcggldamqtdyYSLYERYF-----APRGIAMLTIDMPSVGFSSKWKLtqdsc--------ll 248 Escherichia coli O1... 17865775 183 gflhmpkgdgpf-ptvlmcggldamqtdyYSLYERYF-----APRGIAMLTIDMPSVGFSSKWKLtqdss--------ll 248 Escherichia coli 15806084 112 ------------------------------ALAGRFGa----GPVLAVGSSMGGYVVQTLLQTEPR-------------- 143 Deinococcus radiodu... 15807240 215 gf---------------------vtlksdYRGHGDSEge-arGGYNDPGYTVDVLNAAASLKKDAR-------------- 258 Deinococcus radiodu... 15829520 183 gflhmpkgdgpf-ptvlmcggldamqtdyYSLYERYF-----APRGIAMLTIDMPSVGFSSKWKLtqdsc--------ll 248 Escherichia coli O1... 20141165 183 aflhmpkgdgpf-ptvlmcggldamqtdyYTLYERYF-----APRGIAMLTLDMPSVGFSSKWKLtqdss--------ll 248 Salmonella typhimurium 15642274 183 ylhlrntdspk--pvvlvsagldslqtdmWRLFRDYL-----AKRDIAMLTIDMPSLGASSHWPLtedss--------cl 247 Vibrio cholerae 15790431 187 ateg----------------iaalryekrLHDHDVAPe----EHTLDTVVVDDAVAALDELASADTvdedalf---vagh 243 Halobacterium sp. N... 16123383 183 gflhmptvgsapfptvlmcggldtlqsdyHRLFRDYL-----EPKGIAMLTIDLPSVGASSRWKLtqdts--------yl 249 Yersinia pestis 15799944 183 gflhmpkgdgpf-ptvlmcggldamqtdyYSLYERYF-----APRGIAMLTIDMPSVGFSSKWKLtqdsc--------ll 248 Escherichia coli O1... 17865775 183 gflhmpkgdgpf-ptvlmcggldamqtdyYSLYERYF-----APRGIAMLTIDMPSVGFSSKWKLtqdss--------ll 248 Escherichia coli
15603226 313 gvmNQAVTEKTAISSKQWWGFTLINIVLTLllyplftqwgganepiaaklsfmpLEMGNGIILWLVVSGLVGSllfglwq 392 Pasteurella multocida 15806084 144 ---LTRARCAHHLGCLAGTAGAGAGAAGVSg------------------------SAPAPDPRLARGPHATADre----- 191 Deinococcus radiodu... 15807240 259 ----VNRQRLGVWGHSMGGQLSLRAMLVDPe-----------------------LKAASLWAGVVASYDVLATd------ 305 Deinococcus radiodu... 15829520 249 hqrVLKALPNVPWVDHTRVAAFGFRFGANVavrlay------------lesprlKAVACLGPVVHTLLSDFKCq------ 310 Escherichia coli O1... 20141165 249 hqhVLKALPNVPWVDHTRVAAFGFRFGANVavrlay------------leaprlKAVACLGPVVHALLSDPQRq------ 310 Salmonella typhimurium 15642274 248 hqaVLNQLADLPWVDHFRIGLIGFRFGGNAmarlaf------------lesdkvKACVSLGAPIHDIFTSPNKl------ 309 Vibrio cholerae 15790431 244 sqgGLAAPRIADRHGGVAGVVSLDGPSGTEpdpddvrhl-------ryflepdgDLDEDQEALLAQQQETAPRlvd---- 312 Halobacterium sp. N... 16123383 250 hqqVLQALADVPWVDHQRVSVFGFRFGANVavrlgy------------lepqrvRAVACLGPIVHHLLCNSDSl------ 311 Yersinia pestis 15799944 249 hqrVLKALPNVPWVDHTRVAAFGFRFGANVavrlay------------lesprlKAVACLGPVVHTLLSDFKCq------ 310 Escherichia coli O1... 17865775 249 hqhVLKALPNVPWVDHTRVAAFGFRFGANVavrlay------------lesprlKAVACLGPVVHTLLSDFKCq------ 310 Escherichia coli 15806084 144 ---LTRARCAHHLGCLAGTAGAGAGAAGVSg------------------------SAPAPDPRLARGPHATADre----- 191 Deinococcus radiodu... 15807240 259 ----VNRQRLGVWGHSMGGQLSLRAMLVDPe-----------------------LKAASLWAGVVASYDVLATd------ 305 Deinococcus radiodu... 15829520 249 hqrVLKALPNVPWVDHTRVAAFGFRFGANVavrlay------------lesprlKAVACLGPVVHTLLSDFKCq------ 310 Escherichia coli O1... 20141165 249 hqhVLKALPNVPWVDHTRVAAFGFRFGANVavrlay------------leaprlKAVACLGPVVHALLSDPQRq------ 310 Salmonella typhimurium 15642274 248 hqaVLNQLADLPWVDHFRIGLIGFRFGGNAmarlaf------------lesdkvKACVSLGAPIHDIFTSPNKl------ 309 Vibrio cholerae 15790431 244 sqgGLAAPRIADRHGGVAGVVSLDGPSGTEpdpddvrhl-------ryflepdgDLDEDQEALLAQQQETAPRlvd---- 312 Halobacterium sp. N... 16123383 250 hqqVLQALADVPWVDHQRVSVFGFRFGANVavrlgy------------lepqrvRAVACLGPIVHHLLCNSDSl------ 311 Yersinia pestis 15799944 249 hqrVLKALPNVPWVDHTRVAAFGFRFGANVavrlay------------lesprlKAVACLGPVVHTLLSDFKCq------ 310 Escherichia coli O1... 17865775 249 hqhVLKALPNVPWVDHTRVAAFGFRFGANVavrlay------------lesprlKAVACLGPVVHTLLSDFKCq------ 310 Escherichia coli
15603226 393 rkaqfcwaefgvLSQSASLTTAQLIgRYLLLSLLLFAGLYFLVNliyqyfhvelrflwpllKPLTTERFnlfivyWLPIL 472 Pasteurella multocida 15806084 192 -----------rGGRPGVFARRAPSaDGGGLPRSLRGRDGRFRG-----------------TEFSRRRP-------LHQR 236 Deinococcus radiodu... 15807240 306 -----------wAPPGGEKRQLDDLnRRYLRLLSPNASLADLRG-----------------RPLQLHQG------TGDKE 351 Deinococcus radiodu... 15829520 311 -----------qQVPEMYLDVLASR----LGMHDASDEALRVELn----------------RYSLKVQGllg-rrCPTPM 358 Escherichia coli O1... 20141165 311 -----------sTVPEMYLDVLASR----LGMHDASDEALRVELn----------------RYSLKVQGllg-rrCPTPM 358 Salmonella typhimurium 15642274 310 -----------aAMPKMYLDVLASR----LGKNVVDVRSLSGQLm----------------AWSLKVQGfmsgrrTKTPI 358 Vibrio cholerae 15790431 313 ----------rdYEPDEVLRDKPGRwWDSVLDYDPGALAESID------------------APVFALKTgradpeAQPEL 364 Halobacterium sp. N... 16123383 312 -----------rKVPDMYMDVMASR----LGMADSTDETLNTEMn----------------RYSLKTQGllg-rrCQTPM 359 Yersinia pestis 15799944 311 -----------qQVPEMYLDVLASR----LGMHDASDEALRVELn----------------RYSLKVQGllg-rrCPTPM 358 Escherichia coli O1... 17865775 311 -----------qQVPEMYLDVLASR----LGMHDASDEALRVELn----------------RYSLKVQGllg-rrCPTPM 358 Escherichia coli 15806084 192 -----------rGGRPGVFARRAPSaDGGGLPRSLRGRDGRFRG-----------------TEFSRRRP-------LHQR 236 Deinococcus radiodu... 15807240 306 -----------wAPPGGEKRQLDDLnRRYLRLLSPNASLADLRG-----------------RPLQLHQG------TGDKE 351 Deinococcus radiodu... 15829520 311 -----------qQVPEMYLDVLASR----LGMHDASDEALRVELn----------------RYSLKVQGllg-rrCPTPM 358 Escherichia coli O1... 20141165 311 -----------sTVPEMYLDVLASR----LGMHDASDEALRVELn----------------RYSLKVQGllg-rrCPTPM 358 Salmonella typhimurium 15642274 310 -----------aAMPKMYLDVLASR----LGKNVVDVRSLSGQLm----------------AWSLKVQGfmsgrrTKTPI 358 Vibrio cholerae 15790431 313 ----------rdYEPDEVLRDKPGRwWDSVLDYDPGALAESID------------------APVFALKTgradpeAQPEL 364 Halobacterium sp. N... 16123383 312 -----------rKVPDMYMDVMASR----LGMADSTDETLNTEMn----------------RYSLKTQGllg-rrCQTPM 359 Yersinia pestis 15799944 311 -----------qQVPEMYLDVLASR----LGMHDASDEALRVELn----------------RYSLKVQGllg-rrCPTPM 358 Escherichia coli O1... 17865775 311 -----------qQVPEMYLDVLASR----LGMHDASDEALRVELn----------------RYSLKVQGllg-rrCPTPM 358 Escherichia coli
15603226 473 VFFFVFNGLIVSVQMKqkVASSFTATLLIwsfktalfatggliilwlfHFVPGfmqigpgfdvvglpqfggrwmmmlavi 552 Pasteurella multocida 15806084 237 GPARRGAGVLVGEIG---CWRNRLLRE----------------------------------------------------- 260 Deinococcus radiodu... 15807240 352 VPYSFQVDLANDLRAAgqPFTAYKYEGDN-------------------HNLSG--------------------------- 385 Deinococcus radiodu... 15829520 359 LSGYWKNDPFSPEEDS--RLITSSSADGKl-----------------lEIPFN--------------------------- 392 Escherichia coli O1... 20141165 359 LSGFWKNDPFSPEEES--RLITTSSSDGKl-----------------iEIPFN--------------------------- 392 Salmonella typhimurium 15642274 359 LALGLEGDPVSPYSDN--QLVALFSQGGQa-----------------kKVKSK--------------------------- 392 Vibrio cholerae 15790431 365 VEMHRELLADWRDLDLgeAGRVAFYDGLGhyf-------------qtgHEPSTmth------------------------ 407 Halobacterium sp. N... 16123383 360 LAGFWENDPFSPKEEA--KLICSSSADGKl-----------------lAIPSK--------------------------- 393 Yersinia pestis 15799944 359 LSGYWKNDPFSPEEDS--RLITSSSADGKl-----------------lEIPFN--------------------------- 392 Escherichia coli O1... 17865775 359 LSGYWKNDPFSPEEDS--RLITSSSADGKl-----------------lEIPFN--------------------------- 392 Escherichia coli 15806084 237 GPARRGAGVLVGEIG---CWRNRLLRE----------------------------------------------------- 260 Deinococcus radiodu... 15807240 352 VPYSFQVDLANDLRAAgqPFTAYKYEGDN-------------------HNLSG--------------------------- 385 Deinococcus radiodu... 15829520 359 LSGYWKNDPFSPEEDS--RLITSSSADGKl-----------------lEIPFN--------------------------- 392 Escherichia coli O1... 20141165 359 LSGFWKNDPFSPEEES--RLITTSSSDGKl-----------------iEIPFN--------------------------- 392 Salmonella typhimurium 15642274 359 LALGLEGDPVSPYSDN--QLVALFSQGGQa-----------------kKVKSK--------------------------- 392 Vibrio cholerae 15790431 365 VEMHRELLADWRDLDLgeAGRVAFYDGLGhyf-------------qtgHEPSTmth------------------------ 407 Halobacterium sp. N... 16123383 360 LAGFWENDPFSPKEEA--KLICSSSADGKl-----------------lAIPSK--------------------------- 393 Yersinia pestis 15799944 359 LSGYWKNDPFSPEEDS--RLITSSSADGKl-----------------lEIPFN--------------------------- 392 Escherichia coli O1... 17865775 359 LSGYWKNDPFSPEEDS--RLITSSSADGKl-----------------lEIPFN--------------------------- 392 Escherichia coli
15603226 553 ipqfivftviNHWCYLKTGYIYLGVFFTSLLM 584 Pasteurella multocida 15806084 -------------------------------- Deinococcus radiodurans 15807240 386 -----------NLG---LALRRSVQFFKDTL- 402 Deinococcus radiodurans 15829520 393 ----------PVYRNFDKGLQEITDWIEKRLC 414 Escherichia coli O157:H7 20141165 393 ----------PVYRNFDRALQEITDWINHRLC 414 Salmonella typhimurium 15642274 393 ----------TISQGYEQSLDLAINWLEDELC 414 Vibrio cholerae 15790431 408 --------lqFADNVAEHAVRDVAEWVRGVAD 431 Halobacterium sp. NRC-1 16123383 394 ----------PLYENFHRALLQTSEWLEDKMR 415 Yersinia pestis 15799944 393 ----------PVYRNFDKGXQEITDWIEKRLC 414 Escherichia coli O157:H7 EDL933 17865775 393 ----------PVYRNFDKGLQEITDWIEKRLC 414 Escherichia coli 15806084 -------------------------------- Deinococcus radiodurans 15807240 386 -----------NLG---LALRRSVQFFKDTL- 402 Deinococcus radiodurans 15829520 393 ----------PVYRNFDKGLQEITDWIEKRLC 414 Escherichia coli O157:H7 20141165 393 ----------PVYRNFDRALQEITDWINHRLC 414 Salmonella typhimurium 15642274 393 ----------TISQGYEQSLDLAINWLEDELC 414 Vibrio cholerae 15790431 408 --------lqFADNVAEHAVRDVAEWVRGVAD 431 Halobacterium sp. NRC-1 16123383 394 ----------PLYENFHRALLQTSEWLEDKMR 415 Yersinia pestis 15799944 393 ----------PVYRNFDKGXQEITDWIEKRLC 414 Escherichia coli O157:H7 EDL933 17865775 393 ----------PVYRNFDKGLQEITDWIEKRLC 414 Escherichia coli
Lu S et al.(2020). "CDD/SPARCLE: the conserved domain database in 2020.",