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Molecular Biology Review module of the MLA course on
Introduction to Molecular Biology Information Resources
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References


General Introductions and Primers
  • Access Excellence Graphics Gallery. Provides labeled illustrations of genetic concepts.

  • Biology Project, by the University of Arizona, features brief tutorials and corresponding problem sets on a variety of biology topics, including cell biology, human biology, Mendelian Genetics, molecular biology, and others. A sample problem in the Human Biology section is 'Web Karyotyping,' in which you play the role of a cytogenetic technician and complete three patient karyotypes, then evaluate and diagnose each patient. Another example of a feature that will be of interest is "The Cell Cycle & Mitosis Tutorial."

  • Blazing a Genetic Trail, by the Howard Hughes Medical Institute (HHMI), illustrates the significance of genetic research by recounting the discovery of the gene for cystic fibrosis. It also includes a link to a Brief Key to Basic Genetics

  • Dolan DNA Learning Center is a unit of Cold Spring Harbor Laboratory, serving to provide public genetics education to college, pre-college, and the public. The Center serves as both a clearinghouse for information on DNA science, genetic medicine and biotechnology; and provides an interactive learning environment for students. These goals are reflected in the wealth of information provided at their web site.

  • Genes and Disease web site discusses how genetic factors contribute to human disease, and provides summary information for ~60 genetic diseases with links to related databases and organizations.

  • Green Arrow Tutorials by Sandra Porter, Ph.D., of the Educational Division of Geospiza, Inc.

  • National Human Genome Research Institute (NHGRI) provides Educational Resources for students, teachers, and the general public. It includes an introduction to the human genome project, a talking glossary, fact sheets, and multimedia educational kits on "Exploring Our Molecular Selves".

  • Science Primer, an NCBI resource that explains the science behind the molecular databases at the National Center for Biotechnology Information (NCBI). Topics include bioinformatics, genome mapping, molecular modeling, SNPs, ESTs, microarray technology, molecular genetics, pharmacogenomics, and phylogenetics.

  • Understanding Gene Testing, by Access Excellence, explores how genes are linked to disease and discusses the nature and uses of genetic testing.

  • US Department of Energy's Human Genome Project Information site includes links to a wide variety of educational resources, including a glossary, science primer, and wide variety publications, teaching aids, and online animations.

Articles and Book Chapters
  • New insights as a result of the ENCODE project:
    • Barry, P. 2007. Genome 2.0: Mountains of new data are challenging old views. Science News 172(10):154 (week of Sept. 8).    full text

    • The RNA revolution: Biology's Big Bang. The Economist, Jun 14th 2007. full text

      • The article above also includes a link to:
        RNA: Really New Advances. The Economist, Jun 14th 2007. full text

    • Gerstein MB, Bruce C, Rozowsky JS, Zheng D, Du J, Korbel JO, Emanuelsson O, Zhang ZD, Weissman S, Snyder M. 2007. What is a gene, post-ENCODE? History and updated definition. Genome Research 17(6):669-81 (June).    PubMed;  full text

    • ENCODE Project Consortium. 2007. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature Jun 14;447(7146):799-816   PubMed



Texts (and links to associated glossaries, where available)
The Entrez Books database includes a wide range of texts that may be of interest. A few sample texts are listed below. Direct links to glossaries are provided below when possible.
  • Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., Walter, P. 1994. Molecular Biology of the Cell. 4th ed. New York: Garland Publishing. (online version in Entrez Books; includes glossary)

  • Lewin, B. 1997. Genes VI. New York: Oxford University Press.

  • Lodish, H., Berk, A., Zipursky, S.L., Matsudaira, P., Baltimore, D., Darnell, J.E. 1999. Molecular Cell Biology. 4th ed. New York: W.H. Freeman and Company. (online version in Entrez Books; includes glossary)

  • Strachan, T. and Read, A.P. 1999. Human Molecular Genetics, 2nd ed. New York: John Wiley & Sons. (online version in Entrez Books; includes glossary)

  • Watson, J.D., M. Gilman, J. Witkowski, M. Zoller. 1992. Recombinant DNA. 2d ed. New York: W.H. Freeman and Company, Scientific American Books.

Glossaries and Dictionaries - WWW
In addition to the glossaries associated with the online texts, listed above, you might also find these to be helpful:

Glossaries and Dictionaries - Print Resources
  • Lackie, J.M. and Dow, J.A.T., eds. 1999. Dictionary of Cell Biology. 3rd ed. London: Academic Press.

  • Smith, A.D., et al., eds. 1997. Oxford Dictionary of Biochemistry and Molecular Biology. New York: Oxford University Press.

Molecular Biology Review
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Revised 11/05/2007