Echocardiography in Confirmed and Highly Suspected Symptomatic COVID-19 Patients and Its Impact on Treatment Change

Nadia Benyounes; Clélie Van Der Vynckt; Séverine Tibi; Alexandra Iglesias; Laurence Salomon; Olivier Gout; Thierry Tibi

doi:10.1155/2020/4348598

Echocardiography in Confirmed and Highly Suspected Symptomatic COVID-19 Patients and Its Impact on Treatment Change

Cardiol Res Pract. 2020 Sep 16:2020:4348598. doi: 10.1155/2020/4348598. eCollection 2020.

Authors

Nadia Benyounes¹, Clélie Van Der Vynckt¹, Séverine Tibi², Alexandra Iglesias³, Laurence Salomon⁴, Olivier Gout⁵, Thierry Tibi¹

Affiliations

¹ Cardiology Unit, Rothschild Foundation Hospital, Paris, France.
² British Library, London, UK.
³ Alsacienne School, Paris, France.
⁴ Clinical Research Department, Rothschild Foundation Hospital, Paris, France.
⁵ Neurology Department, Rothschild Foundation Hospital, Paris, France.

Abstract

Background: COVID-19 interacts at multiple levels with the cardiovascular system. The prognosis of COVID-19 infection is known to be worse for patients with underlying cardiovascular diseases. Furthermore, the virus is responsible for many cardiovascular complications. Myocardial injury may affect up to 20% of the critically ill patients. However, echocardiography's impact on the management of patients affected by COVID-19 remains unknown.

Objectives: To explore echocardiography's impact on the management of COVID-19 patients.

Methods: This study was conducted from March 24^th to April 14^th, 2020, in a single center at Adolphe de Rothschild Foundation Hospital, Paris, France. All consecutive inpatients with laboratory and/or CT COVID-19 diagnosis were included in this study. Patients' characteristics (clinical, biological, and imaging) and treatment change induced by echocardiography were collected and analyzed. Patients with and without treatment change induced by echocardiography were compared.

Results: A total of 56 echocardiographies in 42 patients with highly suspected or confirmed COVID-19 were included in the final analyses. The median age was 66 (IQR 60.5-74). Echocardiography induced a treatment change in 9 cases (16%). The analyzed clinical data were not associated with any treatment change induced by echocardiography. D-dimer and Troponin levels were the only biological predictors of the induced treatment change. On echocardiography, higher systolic pulmonary arterial pressure and documented cardiac thrombi were associated with treatment changes in these patients.

Conclusions: Echocardiography may be useful for the management of selected COVID-19 patients, especially those with elevated D-Dimer and Troponin levels, in up to 16% of patients.