Emerging technologies for diagnostics and drug delivery in the fight against COVID-19 and other pandemics

Expert Rev Med Devices. 2020 Oct;17(10):1007-1012. doi: 10.1080/17434440.2020.1792287. Epub 2020 Jul 17.

Abstract

Introduction: A pandemic is the worst-case scenario in the field of infectious diseases. Innovative technologies have the potential to address the challenges associated with the manufacture of personalized drug delivery systems, biosensors, and medical devices during a pandemic. 3D-Printing, microfluidics, and Microelectromechanical systems (MEMS) can provide an important part on this fight, as are cheap, easy to be operated, capable to provide rapid detection and monitoring of a disease, and deliver medicines.

Areas covered: This manuscript answers the question of how these emerging technologies can save lives during a pandemic by avoiding supply chain delays and also by providing rapid diagnostics, disease monitoring, or by offering personalized treatments. The manuscript covers recent approaches in the topic with a focus in manuscripts published in the last year and by emphasising recent regulatory considerations by regulatory agencies in the manufacturing of 3DP systems or other medical devices during COVID.

Expert opinion: New manufacturing techniques are emerging with the ability to address the challenges associated with the development of medical devices or diagnostics, during a pandemic. Are many challenges in order to achieve this and especially in short times that are required under a pandemic attack, which will also be covered in this manuscript.

Keywords: 3D-printing; COVID-19; MEMS devices; diagnostics; disease monitoring; drug delivery; microfluidics; pandemic; personalized treatment.

Publication types

  • Review

MeSH terms

  • COVID-19 / epidemiology*
  • COVID-19 Drug Treatment*
  • Drug Delivery Systems / methods*
  • Humans
  • Micro-Electrical-Mechanical Systems
  • Microfluidics
  • Pandemics*
  • SARS-CoV-2 / physiology