Effects of a high fat diet on intestinal microbiota and gastrointestinal diseases

World J Gastroenterol. 2016 Oct 28;22(40):8905-8909. doi: 10.3748/wjg.v22.i40.8905.

Abstract

Along with the rapid development of society, lifestyles and diets have gradually changed. Due to overwhelming material abundance, high fat, high sugar and high protein diets are common. Numerous studies have determined that diet and its impact on gut microbiota are closely related to obesity and metabolic diseases. Different dietary components affect gut microbiota, thus impacting gastrointestinal disease occurrence and development. A large number of related studies are progressing rapidly. Gut microbiota may be an important intermediate link, causing gastrointestinal diseases under the influence of changes in diet and genetic predisposition. To promote healthy gut microbiota and to prevent and cure gastrointestinal diseases, diets should be improved and supplemented with probiotics.

Keywords: Gastrointestinal diseases; High fat diet; Intestinal microbiota.

Publication types

  • Review

MeSH terms

  • Animals
  • Diet, High-Fat*
  • Gastrointestinal Diseases / microbiology*
  • Gastrointestinal Microbiome*
  • Humans