Oxidation of methyl fluoride and dimethyl ether by ammonia monooxygenase in Nitrosomonas europaea

M R Hyman; C L Page; D J Arp

doi:10.1128/aem.60.8.3033-3035.1994

Oxidation of methyl fluoride and dimethyl ether by ammonia monooxygenase in Nitrosomonas europaea

Appl Environ Microbiol. 1994 Aug;60(8):3033-5. doi: 10.1128/aem.60.8.3033-3035.1994.

Authors

M R Hyman¹, C L Page, D J Arp

Affiliation

¹ Laboratory for Nitrogen Fixation Research, Oregon State University, Corvallis 97331-2902.

Abstract

Methyl fluoride and dimethyl ether were previously identified as inhibitors of ammonia oxidation and N2O production in autotrophic nitrifying bacteria. We demonstrate that methyl fluoride and dimethyl ether are substrates for ammonia monooxygenase and are converted to formaldehyde and a mixture of methanol and formaldehyde, respectively.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Formaldehyde / metabolism
Hydrocarbons, Fluorinated / metabolism*
Hydrocarbons, Fluorinated / pharmacology
Methanol / metabolism
Methyl Ethers / metabolism*
Methyl Ethers / pharmacology
Nitrosomonas / enzymology*
Oxidation-Reduction / drug effects
Oxidoreductases / metabolism*

Substances

Hydrocarbons, Fluorinated
Methyl Ethers
Formaldehyde
fluoromethane
dimethyl ether
Oxidoreductases
ammonia monooxygenase
Methanol